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Aliases for S100A16 Gene

Aliases for S100A16 Gene

  • S100 Calcium Binding Protein A16 2 3
  • Aging-Associated Gene 13 Protein 3 4
  • S100 Calcium-Binding Protein A16 3 4
  • Protein S100-F 3 4
  • S100F 3 4
  • Aging-Associated Protein 13 3
  • Protein S100-A16 3
  • DT1P1A7 3
  • AAG13 3

External Ids for S100A16 Gene

Previous GeneCards Identifiers for S100A16 Gene

  • GC01M9A0123
  • GC01M9A0392
  • GC01M150393
  • GC01M151845
  • GC01M124942

Summaries for S100A16 Gene

GeneCards Summary for S100A16 Gene

S100A16 (S100 Calcium Binding Protein A16) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding and protein homodimerization activity.

UniProtKB/Swiss-Prot for S100A16 Gene

  • Calcium-binding protein. Binds one calcium ion per monomer.

Gene Wiki entry for S100A16 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for S100A16 Gene

Genomics for S100A16 Gene

Regulatory Elements for S100A16 Gene

Genomic Location for S100A16 Gene

153,606,886 bp from pter
153,613,145 bp from pter
6,260 bases
Minus strand

Genomic View for S100A16 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for S100A16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for S100A16 Gene

Proteins for S100A16 Gene

  • Protein details for S100A16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein S100-A16
    Protein Accession:
    Secondary Accessions:
    • A8K439
    • D3DV52
    • Q5RHS6

    Protein attributes for S100A16 Gene

    103 amino acids
    Molecular mass:
    11801 Da
    Quaternary structure:
    • Homodimer.

    Three dimensional structures from OCA and Proteopedia for S100A16 Gene

neXtProt entry for S100A16 Gene

Proteomics data for S100A16 Gene at MOPED

Post-translational modifications for S100A16 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for S100A16 Gene

Antibody Products

No data available for DME Specific Peptides for S100A16 Gene

Domains for S100A16 Gene

Gene Families for S100A16 Gene

  • EFHAND :EF-hand domain containing
  • S100 :S100 calcium binding proteins

Suggested Antigen Peptide Sequences for S100A16 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q96FQ6
  • Contains 2 EF-hand domains.
  • Belongs to the S-100 family.
genes like me logo Genes that share domains with S100A16: view

Function for S100A16 Gene

Molecular function for S100A16 Gene

UniProtKB/Swiss-Prot Function: Calcium-binding protein. Binds one calcium ion per monomer.

Gene Ontology (GO) - Molecular Function for S100A16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding IDA 17030513
GO:0005515 protein binding IPI 16189514
GO:0042803 protein homodimerization activity IPI 17030513
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with S100A16: view

Animal Model Products

CRISPR Products

miRNA for S100A16 Gene

miRTarBase miRNAs that target S100A16

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for S100A16

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for S100A16 Gene

Localization for S100A16 Gene

Subcellular locations from UniProtKB/Swiss-Prot for S100A16 Gene

Nucleus, nucleolus. Cytoplasm. Note=Primarily nucleolar. Translocates from the nucleolus to the cytoplasm in response to an increase of intracellular calcium levels.

Subcellular locations from

Jensen Localization Image for S100A16 Gene COMPARTMENTS Subcellular localization image for S100A16 gene
Compartment Confidence
cytosol 5
nucleus 5
plasma membrane 4
cytoskeleton 1
extracellular 1

Gene Ontology (GO) - Cellular Components for S100A16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005730 nucleolus IDA 17030513
GO:0005737 cytoplasm IDA --
GO:0005829 cytosol IDA 17030513
GO:0005886 plasma membrane IDA --
genes like me logo Genes that share ontologies with S100A16: view

Pathways for S100A16 Gene

SuperPathways for S100A16 Gene

No Data Available

Gene Ontology (GO) - Biological Process for S100A16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0051592 response to calcium ion IEA --
genes like me logo Genes that share ontologies with S100A16: view

No data available for Pathways by source for S100A16 Gene

Transcripts for S100A16 Gene

Unigene Clusters for S100A16 Gene

S100 calcium binding protein A16:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for S100A16

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for S100A16 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e · 7f · 7g ^ 8
SP1: - -
SP2: - - - - -
SP3: - - - -
SP4: - - - -
SP5: - -
SP6: - - - - - - - -
SP7: -

Relevant External Links for S100A16 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for S100A16 Gene

mRNA expression in normal human tissues for S100A16 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for S100A16 Gene

This gene is overexpressed in Esophagus - Mucosa (14.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for S100A16 Gene

SOURCE GeneReport for Unigene cluster for S100A16 Gene Hs.515714

genes like me logo Genes that share expressions with S100A16: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for S100A16 Gene

Orthologs for S100A16 Gene

This gene was present in the common ancestor of chordates.

Orthologs for S100A16 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia S100A16 35
  • 99.68 (n)
  • 99.03 (a)
S100A16 36
  • 99 (a)
(Bos Taurus)
Mammalia S100A16 35
  • 89.64 (n)
  • 90.29 (a)
S100A16 36
  • 90 (a)
(Canis familiaris)
Mammalia S100A16 35
  • 90.61 (n)
  • 90.29 (a)
S100A16 36
  • 90 (a)
(Mus musculus)
Mammalia S100a16 35
  • 83.82 (n)
  • 84.47 (a)
S100a16 16
S100a16 36
  • 72 (a)
(Monodelphis domestica)
Mammalia S100A16 36
  • 84 (a)
(Rattus norvegicus)
Mammalia S100a16 35
  • 87.33 (n)
  • 87 (a)
(Gallus gallus)
Aves S100A16 35
  • 73.05 (n)
  • 68.09 (a)
S100A16 36
  • 61 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.3327 35
Species with no ortholog for S100A16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for S100A16 Gene

Gene Tree for S100A16 (if available)
Gene Tree for S100A16 (if available)

Paralogs for S100A16 Gene

Selected SIMAP similar genes for S100A16 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with S100A16: view

No data available for Paralogs for S100A16 Gene

Variants for S100A16 Gene

Sequence variations from dbSNP and Humsavar for S100A16 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs9660389 -- 153,609,591(+) GGCCA(A/G)TGTAT intron-variant, upstream-variant-2KB
rs9660416 -- 153,609,788(+) TGACC(A/G)CCTTT intron-variant, upstream-variant-2KB
rs9660679 -- 153,609,782(+) CGTCC(C/T)TGACC intron-variant, upstream-variant-2KB
rs9699949 -- 153,611,510(+) ACCTG(C/G)AATTC intron-variant
rs9700179 -- 153,613,108(+) GGCTC(A/G)GTGGG upstream-variant-2KB

Relevant External Links for S100A16 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for S100A16 Gene

Disorders for S100A16 Gene

No disorders were found for S100A16 Gene.

No data available for UniProtKB/Swiss-Prot for S100A16 Gene

Publications for S100A16 Gene

  1. Mapping and characterization of novel (CAG)n repeat cDNAs from adult human brain derived by the oligo capture method. (PMID: 9417904) Reddy P.H. … Tagle D.A. (Genomics 1997) 2 3
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. S100A16, a novel calcium-binding protein of the EF-hand superfamily. (PMID: 17030513) Sturchler E. … Heizmann C.W. (J. Biol. Chem. 2006) 3 4
  4. Structural characterization of human S100A16, a low-affinity calcium binder. (PMID: 21046186) Babini E. … Parigi G. (J. Biol. Inorg. Chem. 2011) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for S100A16 Gene

  • antibodies-online proteins for S100A16
  • antibodies-online antibodies for S100A16
  • antibodies-online kits for S100A16

Sources for S100A16 Gene

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