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S100A11 Gene

protein-coding   GIFtS: 60
GCID: GC01M152004

S100 Calcium Binding Protein A11

(Previous names: S100 calcium-binding protein A11 (calgizzarin), S100 calcium...)
  Search for S100A11
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
S100 Calcium Binding Protein A111 2     S100 Calcium Binding Protein A11 (Calgizzarin)1
S100 Calcium-Binding Protein A11 (Calgizzarin)1 2     HEL-S-432
Metastatic Lymph Node Gene 70 Protein2 3     calgizzarin2
Protein S100-C2 3     Epididymis Secretory Protein Li 432
MLN702 3     Protein S100-A112
S100C2 3     Calgizzarin3
MLN 702 3     S100 Calcium-Binding Protein A113

External Ids:    HGNC: 104881   Entrez Gene: 62822   Ensembl: ENSG000001631917   OMIM: 6031145   UniProtKB: P319493   

Export aliases for S100A11 gene to outside databases

Previous GC identifers: GC01M149845 GC01M147787 GC01M148780 GC01M149221 GC01M148818 GC01M150271 GC01M123382


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for S100A11 Gene:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding
motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the
regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes
include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in
motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene
have been implicated in tumor metastasis. (provided by RefSeq, Jul 2008)

GeneCards Summary for S100A11 Gene:
S100A11 (S100 calcium binding protein A11) is a protein-coding gene. GO annotations related to this gene include calcium-dependent protein binding and calcium ion binding. An important paralog of this gene is S100A6.

UniProtKB/Swiss-Prot: S10AB_HUMAN, P31949
Function: Facilitates the differentiation and the cornification of keratinocytes

Gene Wiki entry for S100A11 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the S100A11 gene promoter:
         NF-1   Sp1   E4BP4   LCR-F1   RORalpha2   AREB6   CREB   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidS100A11 promoter sequence
   Search Chromatin IP Primers for S100A11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat S100A11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21

S100A11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
S100A11 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M152004:  view genomic region     (about GC identifiers)

Start:
152,004,982 bp from pter      End:
152,020,383 bp from pter
Size:
15,402 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: S10AB_HUMAN, P31949 (See protein sequence)
Recommended Name: Protein S100-A11  
Size: 105 amino acids; 11740 Da
Subunit: Homodimer; disulfide-linked
Miscellaneous: Binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins (By
similarity)
3 PDB 3D structures from and Proteopedia for S100A11:
1V4Z (3D)        1V50 (3D)        2LUC (3D)    
Secondary accessions: Q5VTK0

Explore the universe of human proteins at neXtProt for S100A11: NX_P31949

Explore proteomics data for S100A11 at MOPED

Post-translational modifications: 

  • Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with
    NCL/nucleolin which induces nuclear translocation1
  • Ubiquitination2 at Lys27, Lys55
  • Modification sites at PhosphoSitePlus

  • See S100A11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005611.1  
    ENSEMBL proteins: 
     ENSP00000271638  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    EFHAND: EF-hand domain containing
    S100: S100 calcium binding proteins

    Selected InterPro protein domains (see all 6):
     IPR011992 EF-hand-dom_pair
     IPR002048 EF_hand_dom
     IPR013787 S100_Ca-bd_sub
     IPR018247 EF_Hand_1_Ca_BS
     IPR028482 S100A11

    Graphical View of Domain Structure for InterPro Entry P31949

    ProtoNet protein and cluster: P31949

    1 Blocks protein domain: IPB001751 Calcium-binding protein

    UniProtKB/Swiss-Prot: S10AB_HUMAN, P31949
    Similarity: Belongs to the S-100 family
    Similarity: Contains 2 EF-hand domains


    Find genes that share domains with S100A11           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S10AB_HUMAN, P31949
    Function: Facilitates the differentiation and the cornification of keratinocytes

         Genatlas biochemistry entry for S100A11:
    S100 calcium-binding protein A11,bovine CAAF1 homolog,expressed in polynuclear leukocytes,esophagus,epidermal
    diffentiation complex

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding IPI10913138
    GO:0042803protein homodimerization activity IDA10913138
    GO:0044548S100 protein binding IPI10913138
    GO:0048306calcium-dependent protein binding IDA10913138
         
    Find genes that share ontologies with S100A11           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for S100a11):
     reproductive system 

    Find genes that share phenotypes with S100A11           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out S100a11tm1Wen for S100A11

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for S100A11
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    S10AB_HUMAN, P31949: Cytoplasm. Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3
    cytoskeleton2
    extracellular1
    plasma membrane1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001726ruffle IDA10913138
    GO:0005615extracellular space IDA--
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm TAS16130169
    GO:0070062extracellular vesicular exosome IDA19199708

    Find genes that share ontologies with S100A11           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for S100A11
    Interactions:

        GeneGlobe Interaction Network for S100A11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for S100A11 (P319491, 3 ENSP000002716384) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    S100BP042711, 3, ENSP000002917004EBI-701862,EBI-458391 I2D: score=4 STRING: ENSP00000291700
    NCLP193383, ENSP000003181954I2D: score=3 STRING: ENSP00000318195
    ACTBP607093, ENSP000003499604I2D: score=2 STRING: ENSP00000349960
    ANXA1P040833, ENSP000002574974I2D: score=3 STRING: ENSP00000257497
    EGFRP005333, ENSP000002754934I2D: score=1 STRING: ENSP00000275493
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction TAS16130169
    GO:0008156negative regulation of DNA replication TAS10851017
    GO:0008285negative regulation of cell proliferation TAS10851017

    Find genes that share ontologies with S100A11           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for S100A11 (S10AB)

    1 HMDB Compound for S100A11    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    1 DrugBank Compound for S100A11    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Phosphonothreonine-- --target----

    3 Novoseek inferred chemical compound relationships for S100A11 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 36.1 8 9599666 (1), 10913138 (1), 12645011 (1), 18385759 (1) (see all 6)
    glyceraldehyde 3-phosphate 26.6 1 16220529 (1)
    atp 0 1 16220529 (1)



    Find genes that share compounds with S100A11           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for S100A11 gene: 
    NM_005620.1  

    Unigene Cluster for S100A11:

    S100 calcium binding protein A11
    Hs.417004  [show with all ESTs]
    Unigene Representative Sequence: BQ683841
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000271638(uc001ezn.3) ENST00000478109
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat S100A11
      QuantiFast Probe-based Assays in human, mouse, rat S100A11

    Additional mRNA sequence: 

    AK312184.1 BC001410.2 BC014354.1 BT009912.1 D38583.1 D49355.1 D50374.1 X80201.1 

    21 DOTS entries:

    DT.120297  DT.99948256  DT.100893660  DT.85104134  DT.101987311  DT.100893645  DT.120299  DT.121459358 
    DT.121459337  DT.121459388  DT.95138982  DT.101986010  DT.101987309  DT.92048261  DT.100045727  DT.100837566 
    DT.95139080  DT.100033341  DT.120668866  DT.91768417  DT.91982121 

    Selected AceView cDNA sequences (see all 774):

    BM691349 BM856273 AI085736 AA831260 AW836325 AI754798 BM043391 AW583803 
    BI259539 BG109722 BM708266 N39986 BE881861 AI360287 CD671964 AA363879 
    D50374 BQ233247 AA385146 BM458145 BM840377 BQ549827 CB149858 AW604799 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    S100A11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGGCCCCAC
    S100A11 Expression
    About this image


    S100A11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 24) fully expand
     
     Epithelial Cells
             Intermediate Keratinocytes Embryonic Epidermis
     
     Epidermis (Integumentary System)    fully expand to see all 3 entries
             Intermediate Keratinocytes Embryonic Epidermis
     
     Hair
             Primary Hair Placode Cells Hair Follicle
     
     Ovary (Reproductive System)
             Oviduct
     
     Peripheral Nervous System (Nervous System)
             Schwann Precursor Cells Peripheral Nerve Domain
    S100A11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    S100A11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.417004
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for S100A11 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia S100a115
    Gm50681
    S100 calcium binding protein A11 (calgizzarin)5
    predicted gene 50681
    81.25(n)1
    85.42(a)1
      3 (40.51 cM)5
    2770891  XM_006516427.11  XP_006516490.11 
     935204885 
    chicken
    (Gallus gallus)
    Aves S100A111 S100 calcium binding protein A11 71.04(n)
    74.75(a)
      396075  NM_205166.1  NP_990497.1 
    lizard
    (Anolis carolinensis)
    Reptilia S100A116
    S100 calcium binding protein A11
    56(a)
    1 ↔ 1
    GL344049.1(72436-84522)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia s100a111 S100 calcium binding protein A11 62.15(n)
    55.21(a)
      549460  NM_001016706.2  NP_001016706.1 
    zebrafish
    (Danio rerio)
    Actinopterygii s100a10a6
    s100a10b6
    S100 calcium binding protein A10b
    44(a)
    41(a)
    many ↔ many
    many ↔ many
    19(9229419-9230809) ENSDARG00000037425
    16(25637078-25638777) ENSDARG00000025254


    ENSEMBL Gene Tree for S100A11 (if available)
    TreeFam Gene Tree for S100A11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for S100A11 gene
    S100A62  S100A12  S100A122  S100B2  S100A42  S100A32  S100A102  S100Z2  
    S100P2  S100A52  S100A22  S100A92  
    Selected SIMAP similar genes for S100A11 using alignment to 1 protein entry:     S10AB_HUMAN(see all similar genes):
    S100A1    S100A4    S100B    S100Z    S100A10    S100P
    S100A6    S100A12    TCHH    HRNR    S100A2    S100A9
    S100G    S100A13    S100A5    S100A3    FLG    RPTN

    Find genes that share paralogs with S100A11           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for S100A11 (see all 13)
    PGOHUM00000242351 PGOHUM00000242634 PGOHUM00000239828 PGOHUM00000244632 PGOHUM00000233106


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for S100A11 (see all 137)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs788981311,2
    --152004514(+) CTCTTA/GAAATG 1 -- ds50010--------
    rs1833126401,2
    --152004598(+) AGTGCC/TCTCTT 1 -- ds50010--------
    rs30076751,2
    C,H--152004634(+) tgtaaT/Actgtc 1 -- ds50015Minor allele frequency- A:0.00NS EA WA 496
    rs121239751,2
    C,F,A,H--152004804(+) ATAACA/GATAAG 1 -- ds500130Minor allele frequency- G:0.26NA NS EA WA 2956
    rs1865241201,2
    --152004979(+) CTCTCC/TAGTTC 1 -- ds50010--------
    rs1906184881,2
    --152004984(+) TAGTTC/TATGTT 1 -- ut310--------
    rs30883811,2
    C,H--152005100(-) CCTTTC/TC 1 -- ut31 trp35Minor allele frequency- T:0.14MN NS EA 602
    rs1836003871,2
    --152005110(+) GGGGTA/GGGTTT 1 -- ut310--------
    rs2000479721,2
    C--152005145(+) AGGTCC/TGCTTC 2 Q R mis10--------
    rs1502036041,2
    C,F--152005146(+) GGTCCA/C/GCTTCT 3 R G W mis11NA 4530

    HapMap Linkage Disequilibrium report for S100A11 (152004982 - 152020383 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for S100A11:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv872441CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing S100A11
    DNA2.0 Custom Variant and Variant Library Synthesis for S100A11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603114    OMIM disorders: --


    Find genes that share disorders with S100A11           About GenesLikeMe

    6 Novoseek inferred disease relationships for S100A11 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    astrocytoma 22.4 1 10913138 (1)
    colorectal cancer 16.6 8 18340452 (6), 7889529 (1)
    primary tumor 16.4 1 19048101 (1)
    tumors 4.92 5 18340452 (2), 15668896 (2), 9920419 (1)
    cancer 2.64 9 15720411 (4), 15668896 (3)
    metastasis 0 3 19048101 (2), 17523080 (1)

    Genetic Association Database (GAD): S100A11
    Human Genome Epidemiology (HuGE) Navigator: S100A11 (1 document)

    Export disorders for S100A11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for S100A11 gene, integrated from 10 sources (see all 118):
    (articles sorted by number of sources associating them with S100A11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The structure of S100A11 fragment explains a local structural change induced by phosphorylation. (PubMed id 18618420)1, 2, 9 Kouno T.... Kawano K. (J. Pept. Sci. 2008)
    2. Human calgizzarin; one colorectal cancer-related gene selected by a large scale random cDNA sequencing and northern blot analysis. (PubMed id 7889529)1, 2, 9 Tanaka M.... Itakura M. (Cancer Lett. 1995)
    3. Characterization of the human S100A12 (calgranulin C, p6, CAAF1, CGRP) gene, a new member of the S100 gene cluster on chromosome 1q21. (PubMed id 8985590)1, 3, 9 Wicki R.... Heizmann C.W. (Cell Calcium 1996)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17. (PubMed id 7490069)1, 2 Tomasetto C.L.... Rio M.-C. (Genomics 1995)
    8. Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. (PubMed id 1286667)1, 2 Rasmussen H.H....Vandekerckhove J. (Electrophoresis 1992)
    9. Subcellular localization of S100A11 (S100C) in LLC-PK1 renal cells: Calcium- and protein kinase c-dependent association of S100A11 with S100B and vimentin intermediate filaments. (PubMed id 12645011)1, 9 Bianchi R....Donato R. (Microsc. Res. Tech. 2003)
    10. Inhibition of S100A11 gene expression impairs keratinocyte response against vaccinia virus through downregulation of the IL-10 receptor 2 chain. (PubMed id 19577285)1, 9 Bin L....Leung D.Y. (J. Allergy Clin. Immunol. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6282 HGNC: 10488 AceView: S100A11 Ensembl:ENSG00000163191 euGenes: HUgn6282
    ECgene: S100A11 H-InvDB: S100A11

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for S100A11 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for S100A11 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for S100A11 gene:
    Search GeneIP for patents involving S100A11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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