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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

S100A10 Gene

protein-coding   GIFtS: 62
GCID: GC01M151955

S100 calcium binding protein A10

(Previous names: S100 calcium-binding protein A10 (annexin II ligand, calpactin...)
(Previous symbols: ANX2LG, CAL1L)
 Explore 19 diseases affiliated with
S100A10 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for S100A10    

Aliases
for S100A10 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
S100 Calcium Binding Protein A101 2     ANX2L2
CAL1L1 2 3 5     Ca[1]2
ANX2LG1 2 3     GP112
CLP111 2 3     Annexin II Ligand, Calpactin I, Light Polypeptide2
42C1 2     Annexin II Tetramer (AIIt) P11 Subunit2
P111 2     P101
S100 Calcium Binding Protein A10 (Annexin II Ligand, Calpactin I, Light
Polypeptide (P11))1 2
     Protein S100-A102
S100 Calcium-Binding Protein A10 (Annexin II Ligand, Calpactin I, Light
Polypeptide (P11))1 2
     P10 Protein3
Calpactin I Light Chain2 3     P111 2
Calpactin-1 Light Chain2 3     S100 Calcium-Binding Protein A103
Cellular Ligand Of Annexin II2 3     

External Ids:    HGNC: 104871   Entrez Gene: 62812   Ensembl: ENSG000001977477   OMIM: 1140855   UniProtKB: P609033   

Export aliases for S100A10 gene to outside databases

Previous GC identifers: GC01M149796 GC01M147738 GC01M148730 GC01M149171 GC01M148768 GC01M150224 GC01M123333


Summaries
for S100A10 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for S100A10:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding
motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the
regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at
least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and
endocytosis. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: S10AA_HUMAN, P60903
Function: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein
phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase

Gene Wiki entry for S100A10


Genomic Views
for S100A10 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the S100A10 gene promoter:
         Sox5   FOXF2   AML1a   ATF-2   Bach2   AP-4   E47   FOXO4   Hand1   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: S100A10 promoter sequence
   Search SABiosciences Chromatin IP Primers for S100A10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat S100A10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21

S100A10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
S100A10 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M151955:  view genomic region     (about GC identifiers)

Start:
 151,955,386 bp from pter      End:
 151,966,866 bp from pter
Size:
 11,481 bases      Orientation:
 minus strand

Proteins
for S100A10 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: S10AA_HUMAN, P60903 (See protein sequence)
Recommended Name: Protein S100-A10  
Size: 97 amino acids; 11203 Da
Subunit: Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A
(By similarity)
Miscellaneous: Does not appear to bind calcium. Contains 2 ancestral calcium site related to EF-hand domains that have
lost their ability to bind calcium
4 PDB 3D structures from and Proteopedia for S100A10:
1A4P (3D)        1BT6 (3D)        4DRW (3D)        4FTG (3D)    
Secondary accessions: A8K4V8 P08206 Q5T1C5

Explore the universe of human proteins at neXtProt for S100A10: NX_P60903

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P60903

    • S100A10 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002957.1  
    ENSEMBL proteins: 
     ENSP00000357801   ENSP00000357799  

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    ProSpec Recombinant Protein for S100A10
    Uscn Proteins for S100A10

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019897extrinsic to plasma membrane IEA--


    S100A10 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for S100A10

    Protein Domains /
    Families
    for S100A10 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    S100A10 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR011992 EF-hand-like_dom
     IPR013787 S100_Ca-bd_sub
     IPR001751 S100/CaBP-9k_CS

    Graphical View of Domain Structure for InterPro Entry P60903

    ProtoNet protein and cluster: P60903

    1 Blocks protein family: IPB001751 Calcium-binding protein

    UniProtKB/Swiss-Prot: S10AA_HUMAN, P60903
    Similarity: Belongs to the S-100 family


    Function
    for S100A10 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: S10AA_HUMAN, P60903
    Function: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein
    phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase

         Genatlas biochemistry entry for S100A10:
    S100 calcium binding protein A10,epidermal differentiation complex

    miRNA
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    hsa-miR-590-5p hsa-miR-767-3p hsa-miR-551b* hsa-miR-548c-3p hsa-miR-3616-3p hsa-miR-21
    SwitchGear 3'UTR luciferase reporter plasmid: S100A10 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005102receptor binding NAS1831433
    GO:0005509calcium ion binding IEA--


    S100A10 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out S100a10tm1Pggd for S100A10
         4 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for S100a10):
     behavior/neurological  homeostasis/metabolism  integument  nervous system 

    S100A10 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for S100A10 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Prostaglandin Synthesis and Regulation
    		Prostaglandin Synthesis and Regulation1.00
    2wtCFTR and deltaF508 traffic / Membrane expression (norm and CF)
    		Regulation of CFTR activity (norm and CF)0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for S100A10
        Regulation of CFTR activity (norm and CF)

    1 BioSystems Pathway for S100A10 
        Prostaglandin Synthesis and Regulation


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for S100A10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/20 Interacting proteins for S100A10 (P609032, 3 ENSP000003577994) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COPS6Q7L5N12, 3MINT-63928 I2D: score=4 
    SETDB1Q150472, 3MINT-63927 I2D: score=4 
    ANXA2P073553, ENSP000003460324I2D: score=3 STRING: ENSP00000346032
    KCNK3O146493, ENSP000003062754I2D: score=3 STRING: ENSP00000306275
    BADQ929343, ENSP000003091034I2D: score=2 STRING: ENSP00000309103
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction NAS1831433
    GO:0051099positive regulation of binding IEA--
    GO:0071229cellular response to acid IEA--


    S100A10 for ontologies           About GeneDecksing



    Drugs & Compounds
    for S100A10 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    S100A10 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for S100A10

    1 HMDB Compound for S100A10    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    5 Novoseek chemical compound relationships for S100A10 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    arachidonic acid 34.8 10 12163506 (4), 11076800 (2), 12645529 (1)
    phospholipid 25.4 3 18065419 (1)
    calcium 21.7 4 12645529 (1), 8682860 (1), 12163506 (1)
    tyrosine 12.8 10 12645529 (1), 15302870 (1), 1533380 (1), 1831433 (1) (see all 5)
    lysine 9.08 3 11939791 (2)

    Search CenterWatch for drugs/clinical trials and news about S100A10 / S10AA 

    Transcripts
    for S100A10 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for S100A10 gene: 
    NM_002966.2  

    Unigene Cluster for S100A10:

    S100 calcium binding protein A10
    Hs.143873  [show with all ESTs]
    Unigene Representative Sequence: CD388106
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368811(uc001ezl.3) ENST00000368809 ENST00000478574 ENST00000478348


    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate S100A10:
    hsa-miR-590-5p hsa-miR-767-3p hsa-miR-551b* hsa-miR-548c-3p hsa-miR-3616-3p hsa-miR-21
    SwitchGear 3'UTR luciferase reporter plasmid: S100A10 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for S100A10 (see all 7)
    OriGene shRNA RFP: S100A10
    OriGene siRNA: S100A10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat S100A10
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat S100A10
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat S100A10

    Additional cDNA sequence: 

    AK291073.1 BC015973.1 BC105786.1 CR542162.1 D28387.1 M38591.1 M81457.1 

    17 DOTS entries:

    DT.454560  DT.99982891  DT.100705295  DT.100803818  DT.121459339  DT.91951004  DT.40208585  DT.421628 
    DT.40208575  DT.121459332  DT.95261042  DT.100753245  DT.121459342  DT.121459360  DT.87078284  DT.95261112 
    DT.75138673 

    24/552 AceView cDNA sequences (see all 552):

    AW338591 AA376850 BM995883 AA373194 AV705359 AA360215 BM785208 BU146694 
    BM842212 BQ929540 BE620998 BM672556 AA326781 W17136 BM842132 AW273757 
    AI587380 AI720908 N92309 BQ953124 AI144406 BM855142 BM700204 BE122797 

    GeneLoc Exon Structure


    Expression
    for S100A10 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    S100A10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGCAGATCAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    S100A10 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    10 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    PancreasDorsal Pancreatic BudImmature Beta Progenitor CellsPancreas
    PancreasVentral Pancreatic BudImmature Beta Progenitor CellsPancreas
    Skeletal MuscleHyoid Arch MusclesMononuclear MyocytesSkeletal Muscle
    Skeletal MuscleMandibular Arch MusclesMononuclear MyocytesSkeletal Muscle
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    BrainMedulla OblongataBrain
    EyeRetinaEye
    Intermediate MesodermIntermediate MesodermIntermediate Mesoderm
    Neural TubeMetencephalonNeural Tube
    Spinal CordSpinal Ventral ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See S100A10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for S100A10

    SOURCE GeneReport for Unigene cluster: Hs.143873
        SABiosciences Custom PCR Arrays for S100A10
    Primer
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    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for S100A10

    Orthologs
    for S100A10 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for S100A10 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves S100A101 S100 calcium binding protein A10 78.69(n)
    89.69(a)    		   396506  NM_205506.1  NP_990837.1 
    lizard
    (Anolis carolinensis)    		 Reptilia S100A106
    		 --
    		 68(a)
    		 1 ↔ 1
    		 GL344049.1(38461-39863)
    African clawed frog
    (Xenopus laevis)    		 Amphibia BC041295.12   -- 72.89(n)    BC041295.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii s100a10b1 S100 calcium binding protein A10b 57.73(n)
    52.58(a)    		   406276  NM_213003.1  NP_998168.1 


    ENSEMBL Gene Tree for S100A10 (if available)
    TreeFam Gene Tree for S100A10 (if available) 

    Paralogs
    for S100A10 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for S100A10 gene
    S100A112  S100A62  S100A12  S100A122  S100A82  S100B2  S100A42  S100A32  
    S100Z2  S100A22  S100P2  S100A52  S100A92  
    18/24 SIMAP similar genes for S100A10 using alignment to 3 protein entries:     S10AA_HUMAN (see all proteins) (see all similar genes):
    S100Z    S100P    S100A11    S100A16    S100B    S100A1
    S100A4    S100A9    S100A14    S100A12    S100A5    S100A13
    TCHH    HRNR    S100A7L2    S100A6    FLG2    S100G

    S100A10 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for S100A10
    PGOHUM00000237107


    Genomic Variants
    for S100A10 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/206 NCBI SNPs in S100A10 are shown (see all 206)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs13878351,2
    		C,F,A,H,--151954892(-) GCAGTG/ACACTT 1 -- ds500136Minor allele frequency- A:0.12EA NS NA WA CSA 3260
    rs741267631,2
    		C,--151954905(+) CGTGTA/GTAAGT 1 -- ds50012Minor allele frequency- G:0.04WA 120
    rs1499549131,2
    		--151954950(+) ACTTAA/GTAGAT 1 -- ds50010--------
    rs66786721,2
    		C,F,H,--151955009(+) TGGTTC/TTCCTA 1 -- ds500133Minor allele frequency- T:0.27NS EA NA CSA WA 3017
    rs13878341,2
    		C,F,O,H,--151955052(-) ATCCAT/ATTTTC 1 -- ds500138Minor allele frequency- A:0.07NS EA NA WA CSA 3028
    rs1440851061,2
    		--151955057(+) TTGGAC/TTCAGA 1 -- ds50010--------
    rs65876401,2
    		C,F,A,H,--151955230(+) GAAGTC/TAGACT 1 -- ds500135Minor allele frequency- T:0.39NS NA EA WA CSA 3013
    rs767874951,2
    		C,--151955279(+) TCTGTA/GANNNN 1 -- ds50010--------
    rs1486512521,2
    		--151955464(+) TATCTC/GGTATT 1 -- ut310--------
    rs1828623101,2
    		--151955501(+) TGAGAA/GTTAGA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for S100A10 (151955386 - 151966866 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for S100A10: --

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    Disorders / Diseases
    for S100A10 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    S100A10 for disorders           About GeneDecksing

    OMIM gene information: 114085    OMIM disorders: --

    19 diseases for S100A10:    About MalaCards
    major depressive disorder    irritable bowel syndrome    borna disease    atopic dermatitis
    renal cell carcinoma    cystic fibrosis    alcoholic hepatitis    dermatitis
    liver disease    fibrosis    alcoholism    colorectal cancer
    lung cancer    breast cancer    hepatitis    hypoxia
    thyroiditis    carcinoma    anaplastic carcinoma

    1 disease from the University of Copenhagen DISEASES database for S100A10:
    Borna disease

    3 Novoseek disease relationships for S100A10 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    metastasis 0 5 15574370 (2), 18608216 (1), 20085458 (1), 17695432 (1)
    tumors 0 5 18608216 (2), 17083565 (2)
    cancer 0 6 15574370 (3), 14570893 (2), 20085458 (1)

    Human Genome Epidemiology (HuGE) Navigator: S100A10 (5 documents)
    Tumor Gene Database (TGDB): S100A10

    Export disorders for S100A10 gene to outside databases

    Publications
    for S100A10 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for S100A10 gene, integrated from 9 sources (see all 112):
    (articles sorted by number of sources associating them with S100A10)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Primary structure of human, chicken, and Xenopus laevis p11, a cellular ligand of the Src-kinase substrate, annexin II. (PubMed id 1831433)1, 2, 9 Kube E.... Gerke V. (1991)
    2. Cloning and characterization of the human gene encoding p11: structural similarity to other members of the S-100 gene family. (PubMed id 1533380)1, 2, 9 Harder T.... Gerke V. (1992)
    3. cDNA sequence of human p11 calpactin I light chain. (PubMed id 1386341)1, 2, 9 Dooley T.P.... Simon M. (1992)
    4. Physical mapping of a functional cluster of epidermal differentiation genes on chromosome 1q21. (PubMed id 8276421)1, 3, 9 Volz A....Mischke D. (1993)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. The crystal structure of a complex of p11 with the annexin II N- terminal peptide. (PubMed id 9886297)1, 2 Rety S.... Lewit-Bentley A. (1999)
    8. Interferon-gamma induces p11 gene and protein expression in human epithelial cells through interferon-gamma-activated sequences in the p11 promoter. (PubMed id 12645529)1, 9 Huang X.L....Shelhamer J.H. (2003)
    9. S100A10, annexin A2, and annexin a2 heterotetramer as candidate plasminogen receptors. (PubMed id 15574370)1, 9 Kwon M....Waisman D.M. (2005)
    10. Epidermal growth factor induces p11 gene and protein expression and down-regulates calcium ionophore-induced arachidonic acid release in human epithelial cells. (PubMed id 12163506)1, 9 Huang X.L....Shelhamer J.H. (2002)

    External Searches for S100A10 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing S100A10 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6281 HGNC: 10487 AceView: S100A10 Ensembl:ENSG00000197747 euGenes: HUgn6281
    ECgene: S100A10 H-InvDB: S100A10

    Other Databases showing S100A10 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing S100A10 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for S100A10 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for S100A10 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for S100A10 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for S100A10 gene:
    Search GeneIP for patents involving S100A10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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