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RXRB Gene

protein-coding GIFtS: 69

GC06M033270

retinoid X receptor, beta
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DAUDI6 ^²
H-2RIIBP ^¹, ²
MGC1831 ^²
NR2B2 ^¹, ², ³
RCoR-1 ^¹, ²

Descriptions
MHC class I promoter binding protein ^²
Nuclear receptor subfamily 2 group B member 2 ^³
Retinoid X receptor beta ^³
retinoid X receptor, beta ^²

External Ids
HGNC: 10478¹
Entrez Gene: 6257²
UniProtKB: P28702³
Ensembl: ENSG00000204231⁷

Search outside databases for aliases for RXRB gene

Previous GC identifers: GC06M033164 GC06M033208

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for RXRB:

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are

involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the

retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and

transcriptional function on their respective response elements. The gene lies within the major

histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced

transcript variant has been described, but its full length sequence has not been determined.

[provided by RefSeq]

UniProtKB/Swiss-Prot: RXRB_HUMAN, P28702

Function: Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis

retinoic acid (9C-RA)

Gene Wiki entry for RXRB (Retinoid_X_receptor_beta)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the RXRB gene

Entrez Gene cytogenetic band: 6p21.3 Ensembl cytogenetic band: 6p21.32 HGNC cytogenetic band: 6p21.3

RXRB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M033270: (about GC identifiers)

Start:	33,269,343 bp from pter
End:	33,276,410 bp from pter
Size:	7,068 bases
Orientation:	minus strand

2 alternative locations:

Chr6-,c6_QBL 33,233,043-33,240,144

Chr6-,c6_COX 33,230,071-33,237,136

RefSeq DNA sequence:

NC_000006.10 NT_007592.14 NT_113891.1 NT_113897.1

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: RXRB_HUMAN, P28702 (See protein sequence)

Recommended Name: Retinoic acid receptor RXR-beta

Size: 533 amino acids; 56922 Da

Subcellular location: Nucleus

PDB structure from and Proteopedia :

1H9U (3D)

1UHL (3D)

Secondary accessions: P28703

REFSEQ proteins: NP_068811.1

ENSEMBL proteins:

ENSP00000378607 ENSP00000363813 ENSP00000363815 ENSP00000363812 ENSP00000363817

Human Recombinant Proteins

	Invitrogen human recombinant proteins for RXRB
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Enzo Life Sciences proteins for RXRB
	Recombinant Proteins from Abcam (Retinoid X Receptor beta)
	Human Recombinant Proteins from Abnova (RXRB)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	7990953

About this table

Antibodies for RXRB:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of RXRB
	Sigma-Aldrich Antibodies for RXRB
	R&D Systems Antibodies for RXRB (RXR beta/NR2B2)
	Antibodies from Abcam (Retinoid X Receptor beta), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (RXRB)
	Novus Biologicals Antibodies for RXRB

Assays for RXRB:

	Invitrogen Assays for RXRB
	Millipore Kits and Assays for the Analysis of RXRB
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P28702

ProtoNet protein and cluster: P28702

2 Blocks protein families:

IPB000003 Retinoic acid receptor signature

IPB001723 Steroid hormone receptor signature

UniProtKB/Swiss-Prot: RXRB_HUMAN, P28702

Domain: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a

C-terminal steroid-binding domain

Similarity: Belongs to the nuclear hormone receptor family. NR2 subfamily

Similarity: Contains 1 nuclear receptor DNA-binding domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (RXRB)
		Millipore RNAi Products for the Analysis of RXRB Gene knock-down
		Abnova Chimera RNAi Products for Gene knock-down (RXRB)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_021976

Applied Biosystems Silencer® siRNAs for RXRB

Sigma-Aldrich siRNA and siRNA Panels for RXRB

Sigma-Aldrich shRNA Panels and shRNA for RXRB

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for RXRB
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_021976
Myc/DDK tagged cDNA clone in CMV expression vector: NM_021976
untagged cDNA clone in CMV expression vector: NM_021976

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_021976

UniProtKB/Swiss-Prot: RXRB_HUMAN, P28702

Function: Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis

retinoic acid (9C-RA)

Genatlas biochemistry entry for RXRB:

retinoic acid X receptor binding and activated by 9-cis-retinoic acid,only (9-cis-RA),beta

subunit,obligate member of heterodimeric nuclear receptors,steroid/thyroid/retinoic receptor

superfamily

15/19 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Rxrb) (see all 19 ):

	behavior/neurological	cellular	craniofacial	embryogenesis
endocrine/exocrine gland	growth/size	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism
immune system	lethality-prenatal/perinatal	liver/biliary system	muscle	nervous system

5/9 Gene Ontology (GO) molecular function terms (links to tree view) (see all 9 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	NAS	1662118
GO:0003706	ligand-regulated transcription factor activity	IDA	7990953
GO:0003707	steroid hormone receptor activity	IEA	--
GO:0003713	transcription coactivator activity	TAS	1662118
GO:0004886	retinoid-X receptor activity	TAS	1662118

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/9 Sigma-Aldrich "Your Favorite Gene" Pathways for RXRB (Your Favorite Gene powered by Ingenuity) (see all 9 )

Non-Small Cell Lung Cancer Signaling
TR/RXR Activation
Thyroid Cancer Signaling
Aryl Hydrocarbon Receptor Signaling
Small Cell Lung Cancer Signaling

GeneDecks RXRB for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for RXRB

5/26 Interacting proteins for RXRB (P28702² ENSP00000363817³) via UniProtKB, MINT, and/or STRING (see all 26 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RARA	P10276²	MINT-67313
SPOP	O43791²	MINT-67766
NR1H3	ENSP00000342470³	STRING (score=.916)
ABCA1	ENSP00000363868³	STRING (score=.888)
GTF2B	ENSP00000359531³	STRING (score=.884)

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006350	transcription	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for RXRB

Sigma-Aldrich Small Molecules for RXRB:

Activator Antagonist Ligand

Compounds for RXRB available from Tocris Bioscience

Compound	Action	CAS number
Liarozole hydrochloride	Blocks retinoic acid metabolism	[145858-50-0]
Fenretinide	Synthetic retinoid. Potent anti-cancer agent	[65646-68-6]
Retinoic acid	Endogenous retinoic acid receptor agonist. Also modulates PPARdelta	[302-79-4]

About this table

1 Novoseek chemical compound relationship for RXRB gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
oligonucleotide	2.63	1	15585599 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (RXRB)
		Millipore RNAi Products for the Analysis of RXRB Gene knock-down
		Abnova Chimera RNAi Products for Gene knock-down (RXRB)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_021976

Sigma-Aldrich siRNA and siRNA Panels for RXRB

Sigma-Aldrich shRNA Panels and shRNA for RXRB

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_021976

REFSEQ mRNAs for RXRB gene:

NM_021976.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_021976

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_021976
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_021976
                                 untagged cDNA clone in CMV expression vector: NM_021976

Additional cDNA sequence:

AB209244.1 AK225842.1 AK295759.1 AK300402.1 AK301096.1 AK302125.1 BC001167.1 BT007280.1

CR618812.1 M84820.1 U00961.1 X63522.1 X65463.1 X66424.1

15 DOTS entries:

DT.118619 DT.100811035 DT.91841173 DT.118621 DT.100798333 DT.100029702 DT.100811028 DT.448809

DT.95145990 DT.100798335 DT.75187712 DT.100767296 DT.100798340 DT.121346999 DT.100830297

24/297 AceView cDNA sequences (see all 297 ):

AA336809 BM549884 BI906740 AI888632 CR618812 AW008891 BE328430 BX103701

BM014020 F13008 NM_021976 BQ063317 AU105238 AW026020 CK903550 BF875011

BU726451 BG680532 AI669725 BI962866 AI003461 AU099317 BI962952 AA195311

highest scoring ESTs for RXRB:

M84820 AA010151 AL044221 AU099317 BC001167 BE242137 BE260279 BE882266 BF311397 BG912551

Unigene Cluster for RXRB:

Retinoid X receptor, beta

Hs.388034 [show with all ESTs]

Unigene Representative Sequence: NM_021976

GeneLoc Exon Structure

5 Ensembl transcripts including schematic representations:

ENST00000395178 ENST00000374681 ENST00000374683 ENST00000374680 ENST00000374685

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

RXRB expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for RXRB

¹ / ² / ³

8 probe-sets matching RXRB gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
37763_at²^{, 3}	U95-A	2	1.00	0.50	0.89	1.14	AL031228	0.20	0.08	0.15	1
1362_s_at²^{, 3}	U95-A	2	1.00	0.50	0.90	0.86	M84820	1.00	1.00	1.00	1
209148_at²^{, 3}	U133-A	2	1.00	0.50	--	--	BC001167	0.80	1.00	0.91	1
215099_s_at²^{, 3}	U133-A	2	1.00	0.50	--	--	BF337038	0.40	1.00	0.76	1
215098_at²^{, 3}	U133-A	1	0.82	1.00	--	--	BF337038	0.40	1.00	0.76	1
209148_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--
215099_s_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--
215098_at²	U133Plus2	1	0.82	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ATTTTTGCCC

SOURCE GeneReport for Unigene cluster: Hs.388034
Expression variation in blood from EXPOLDB for RXRB
UniProtKB/Swiss-Prot: RXRB_HUMAN, P28702
Tissue specificity: Expressed in a variety of tumor cell lines

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for RXRB gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	RXRB¹	--	retinoid X receptor, beta	95.11(n) 98.68(a)	481735 XM_857634.1 XP_862727.1
chimpanzee (Pan troglodytes)	RXRB¹	--	retinoid X receptor, beta	99.75(n) 100(a)	462601 XM_001168893.1 XP_001168893.1
cow (Bos taurus)	RXRB¹	--	retinoid X receptor, beta	93.3(n) 98.68(a)	504943 XM_877602.2 XP_882695.1
rat (Rattus norvegicus)	Rxrb¹	--	retinoid X receptor beta	91.38(n) 97.68(a)	361801 NM_206849.2 NP_996731.2
mouse (Mus musculus)	Rxrb^{1, 5}	17 (18.49 cM)⁵	retinoid X receptor beta^{1, 5}	91.67(n)¹ 97.12(a)¹	20182¹ NM_011306.3¹ NP_035436.1¹ AF100956⁵ AK013718⁵ (see all 19)

About this table Species with no ortholog for RXRB

ENSEMBL Gene Tree for RXRB

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for RXRB gene

RXRG² RXRA²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/39 NCBI SNPs in RXRB are shown (see all 39 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 74)

AB	SNP ID	Valid	Chr 6 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs6531^1,2	A,C,F,H	33271429(-)	`TCCTTT/CTCACA`	1	F/F	syn¹ trp³		11		MN EU EA WA NA	1130
--	rs3117040^1,2	A,C,F,H	33272713(-)	`GAATGG/TTAAAA`	1	--	int¹		5		EU EA WA MN	512
	rs2076310^1,2	A,C,F,H	33274012(-)	`TATCAC/TCACCT`	1	--	int¹		22		EA MN CSAM EU WA NS NA	2836
	rs2744527^1,2	C	33273912(-)	`GACGCG/CATTGG`	1	--	int¹		5		MN CSAM EA	404
	rs2982274^1,2	C	33273968(-)	`AGCAAG/TTGACC`	1	--	int¹		5		MN CSAM EA	404
	rs2744528^1,2	C	33273840(-)	`ACTGGA/TTCATC`	1	--	int¹		5		MN CSAM EA	404
	rs2982273^1,2	C	33273972(-)	`TCAGAG/CCAAGT`	1	--	int¹		5		MN CSAM EA	404
	rs2744526^1,2	C	33273924(-)	`GCTGAG/AATGTA`	1	--	int¹		5		MN CSAM EA	404
--	rs10548957^1,2	C	33271618(+)	`CAAAG-/AGGGGTC`	1	--	int¹		0	--	--	--	--
--	rs17215168^1,2	F	33272668(+)	`AAAAAT/ATTTTT`	1	--	int¹		1		MN	92

About this table

HapMap Linkage Disequilibrium images for RXRB (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 180246

3 Novoseek disease relationships for RXRB gene

Disease	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
breast cancer	2	12767074 (1)
tumors	2	8180126 (1)
schizophrenia	2	11840500 (2)

About this table

Genetic Association Database: RXRB
Human Genome Epidemiology Navigator: RXRB (11 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/93 PubMed articles for RXRB gene (see all 93 ):

Mutation analysis of the retinoid X receptor beta, nuclear-related receptor 1, and peroxisome proliferator-activated receptor alpha genes in schizophrenia and alcohol dependence: possible haplotype association of nuclear-related receptor 1 gene to alcohol dependence. (PubMed id 11840500)^{1, 3, 6} Ishiguro H....Arinami T. (2002)
Cloning and chromosome mapping of human retinoid X receptor beta: selective amino acid sequence conservation of a nuclear hormone receptor in mammals. (PubMed id 8381386)^{1, 3, 4} Fleischhauer K.... Yang S.Y. (1993)
Isolation of a full-length cDNA clone encoding a N-terminally variant form of the human retinoid X receptor beta. (PubMed id 1315958)^{1, 3, 4} Fleischhauer K....Yang S.Y. (1992)
Mapping of RXRB to human chromosome 6p21.3. (PubMed id 8257090)^{1, 2, 3} Fitzgibbon J....Povey S. (1993)
Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. (PubMed id 1310259)^{1, 3, 4} Leid M....Chambon P. (1992)
Structural variants in the retinoid receptor genes in patients with schizophrenia and other psychiatric diseases. (PubMed id 15635645)^{3, 6} Feng J....Sommer S.S. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{3, 4} Mungall A.J.... Beck S. (2003)
The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12. (PubMed id 11782480)^{3, 4} Love J.D....Schwabe J.W. (2002)
Linkage disequilibrium between HLA-DPB1 alleles and retinoid X receptor beta haplotypes. (PubMed id 12175732)^{1, 3} Rajsbaum R....Awdeh Z.L. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 6257	HGNC: 10478	AceView: RXRB	Ensembl:ENSG00000204231	euGenes: HUgn6257
ECgene: RXRB	H-InvDB: RXRB

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for RXRB	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for RXRB
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for RXRB:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for RXRB-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for RXRB		Antibodies for RXRB
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for RXRB		Small molecules for RXRB
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (RXRB)
	Antibodies (RXRB)
	Chimera RNAi (RXRB)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Retinoid X Receptor beta)
	Antibodies (Retinoid X Receptor beta)

Search OriGene for RXRB

Tocris compounds for RXRB

	Drugs/Proteins for RXRB
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for RXRB

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

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RXRB Gene at Home site.
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RXRB Gene

protein-coding GIFtS: 69

Aliases &
Descriptions
for RXRB

Summaries
for RXRB

Genomic Location
for RXRB

Proteins
for RXRB

Protein Domains/
Families
for RXRB

Gene Function
for RXRB

Pathways & Interactions
for RXRB

Drugs & Compounds
for RXRB

Transcripts
for RXRB

Expression
for RXRB

Orthologs
for RXRB

Paralogs
for RXRB

SNPs/Variants
for RXRB

Disorders & Mutations
for RXRB

Medical News
for RXRB

Publications
for RXRB

Search for RXRB

Genome Databases showing RXRB

Other Databases showing RXRB

Specialized Databases showing RXRB

Licensable Technologies
for RXRB

Services
for RXRB

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

RXRB Gene

protein-coding GIFtS: 69

Aliases & Descriptionsfor RXRB

Summariesfor RXRB

Genomic Locationfor RXRB

Proteinsfor RXRB

Protein Domains/Familiesfor RXRB

Gene Functionfor RXRB

Pathways & Interactionsfor RXRB

Drugs & Compoundsfor RXRB

Transcriptsfor RXRB

Expression for RXRB

Orthologsfor RXRB

Paralogsfor RXRB

SNPs/Variantsfor RXRB

Disorders & Mutationsfor RXRB

Medical Newsfor RXRB

Publicationsfor RXRB

Search for RXRB

Genome Databases showing RXRB

Other Databases showing RXRB

Specialized Databases showing RXRB

Licensable Technologiesfor RXRB

Servicesfor RXRB

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for RXRB

Summaries
for RXRB

Genomic Location
for RXRB

Proteins
for RXRB

Protein Domains/
Families
for RXRB

Gene Function
for RXRB

Pathways & Interactions
for RXRB

Drugs & Compounds
for RXRB

Transcripts
for RXRB

Expression
for RXRB

Orthologs
for RXRB

Paralogs
for RXRB

SNPs/Variants
for RXRB

Disorders & Mutations
for RXRB

Medical News
for RXRB

Publications
for RXRB

Licensable Technologies
for RXRB

Services
for RXRB