Aliases for RXFP4 Gene
External Ids for RXFP4 Gene
Previous HGNC Symbols for RXFP4 Gene
Previous GeneCards Identifiers for RXFP4 Gene
GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008]
GeneCards Summary for RXFP4 Gene
RXFP4 (Relaxin/Insulin-Like Family Peptide Receptor 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and angiotensin type II receptor activity. An important paralog of this gene is ACKR3.
UniProtKB/Swiss-Prot for RXFP4 Gene
High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation.