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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RUFY2 Gene

protein-coding   GIFtS: 52
GCID: GC10M070100

RUN And FYVE Domain Containing 2

Alzheimer's & Parkinson's Diseases Congress
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RUN And FYVE Domain Containing 21 2     RUN And FYVE Domain-Containing 22
Rab4-Interacting Protein Related2 3     RUN And FYVE Domain-Containing Protein 22
RABIP4R2 3     Run- And FYVE-Domain Containing Protein2
ZFYVE132     KIAA15373
Antigen MU-RMS-40.172     

External Ids:    HGNC: 197611   Entrez Gene: 556802   Ensembl: ENSG000002041307   OMIM: 6103285   UniProtKB: Q8WXA33   

Export aliases for RUFY2 gene to outside databases

Previous GC identifers: GC10M069186 GC10M069993 GC10M069445 GC10M069770 GC10M064103


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RUFY2 Gene: 
RUFY2 (RUN and FYVE domain containing 2) is a protein-coding gene. Diseases associated with RUFY2 include alzheimer's disease. GO annotations related to this gene include metal ion binding. An important paralog of this gene is RUNDC3A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RUFY2 gene promoter:
         CHOP-10   SRY   Elk-1   NCX/Ncx   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRUFY2 promoter sequence
   Search SABiosciences Chromatin IP Primers for RUFY2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RUFY2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q21.3   Ensembl cytogenetic band:  10q21.3   HGNC cytogenetic band: 10q22.2

RUFY2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RUFY2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M070100:  view genomic region     (about GC identifiers)

Start:
70,100,864 bp from pter      End:
70,167,051 bp from pter
Size:
66,188 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RUFY2_HUMAN, Q8WXA3 (See protein sequence)
Recommended Name: RUN and FYVE domain-containing protein 2  
Size: 655 amino acids; 75055 Da
Subunit: Interacts with BMX
Subcellular location: Nucleus (By similarity)
Sequence caution: Sequence=CAI17232.1; Type=Erroneous gene model prediction;
Secondary accessions: B3KXB2 Q5TC48 Q8IW33 Q96P51 Q9P1Z1
Alternative splicing: 4 isoforms:  Q8WXA3-1   Q8WXA3-2   Q8WXA3-3   Q8WXA3-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RUFY2: NX_Q8WXA3

Explore proteomics data for RUFY2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WXA3

  • RUFY2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RUFY2 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001035882.1  NP_001265154.1  NP_060457.4  

    ENSEMBL proteins: 
     ENSP00000433197   ENSP00000474574   ENSP00000473462   ENSP00000265865   ENSP00000341727  
     ENSP00000373420   ENSP00000382151   ENSP00000404986  

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    Cloud-Clone Corp. Proteins for RUFY2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    RUFY2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZFYVE: Zinc fingers, FYVE domain containing

    5 InterPro protein domains:
     IPR000306 Znf_FYVE
     IPR017455 Znf_FYVE-rel
     IPR013083 Znf_RING/FYVE/PHD
     IPR004012 Run
     IPR011011 Znf_FYVE_PHD

    Graphical View of Domain Structure for InterPro Entry Q8WXA3

    ProtoNet protein and cluster: Q8WXA3

    1 Blocks protein domain: IPB000306 Zn-finger

    UniProtKB/Swiss-Prot: RUFY2_HUMAN, Q8WXA3
    Similarity: Contains 1 FYVE-type zinc finger
    Similarity: Contains 1 RUN domain


    RUFY2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0046872metal ion binding IEA--
         
    RUFY2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RUFY2 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RUFY2 
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    SwitchGear 3'UTR luciferase reporter plasmidRUFY2 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RUFY2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/11 Interacting proteins for RUFY2 (Q8WXA32, 3 ENSP000003734204) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DUSP23Q9BVJ72, 3MINT-8254732 I2D: score=2 
    SF3B3Q153932, 3, ENSP000003057904MINT-8270308 I2D: score=2 STRING: ENSP00000305790
    BMXP518133, ENSP000003087744I2D: score=2 STRING: ENSP00000308774
    EPHA3P293203, ENSP000003374514I2D: score=1 STRING: ENSP00000337451
    CHIAENSP000003418284STRING: ENSP00000341828
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RUFY2

    Search CenterWatch for drugs/clinical trials and news about RUFY2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RUFY2 gene (3 alternative transcripts): 
    NM_001042417.1  NM_001278225.1  NM_017987.4  

    Unigene Cluster for RUFY2:

    RUN and FYVE domain containing 2
    Hs.653144  [show with all ESTs]
    Unigene Representative Sequence: NM_017987
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000466493(uc001jnz.1) ENST00000484083 ENST00000463210 ENST00000466187
    ENST00000602465 ENST00000265865 ENST00000473398 ENST00000491118 ENST00000472394
    ENST00000342616(uc001joe.1) ENST00000388768(uc001joa.3 uc001job.3)
    ENST00000399200(uc001joc.3 uc010qiw.2 uc001jod.1 uc009xpv.1)
    ENST00000454950

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    8/40 QIAGEN miScript miRNA Assays for microRNAs that regulate RUFY2 (see all 40):
    hsa-let-7d hsa-miR-106a hsa-miR-578 hsa-miR-218 hsa-miR-519a hsa-let-7g hsa-let-7a hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidRUFY2 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Additional mRNA sequence: 

    AB040970.1 AF411980.1 AF461266.1 AK055646.1 AK091629.1 AK294211.1 AY528716.1 BC020659.2 
    BC041092.1 BC062660.1 

    14 DOTS entries:

    DT.95263919  DT.100678426  DT.409243  DT.92419375  DT.95155659  DT.99942629  DT.97838276  DT.92008348 
    DT.95230056  DT.40113994  DT.40198251  DT.75109463  DT.75180673  DT.92424344 

    24/87 AceView cDNA sequences (see all 87):

    CB995997 CA422079 BQ723438 AF461266 AA251609 BC062660 AW337129 AI221958 
    AB040970 AF411980 BQ776460 NM_017987 BC041092 BG707400 AU117462 AW271465 
    BQ776772 H61603 AW014452 AA258119 AK055646 BX486877 BI546055 AI039928 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RUFY2 expression in normal human tissues (normalized intensities)      RUFY2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGCCAGGGA
    RUFY2 Expression
    About this image


    RUFY2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Uterus (Reproductive System)
             endometrial endothelial cell   
     
     Eye (Sensory Organs)
             nGnG Amacrine Cells Inner Nuclear Layer

    See RUFY2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RUFY2

    SOURCE GeneReport for Unigene cluster: Hs.653144

    UniProtKB/Swiss-Prot: RUFY2_HUMAN, Q8WXA3
    Tissue specificity: Expressed in brain, lung and testis

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RUFY2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RUFY2 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rufy21 , 5 RUN and FYVE domain-containing 21, 5 86.96(n)1
    94.88(a)1
      10 (32.51 cM)5
    704321  NM_027425.31  NP_081701.21 
     629802235 
    chicken
    (Gallus gallus)
    Aves RUFY21 RUN and FYVE domain containing 2 81.68(n)
    89.6(a)
      423687  XM_421568.3  XP_421568.2 
    lizard
    (Anolis carolinensis)
    Reptilia RUFY26
    Uncharacterized protein
    80(a)
    1 ↔ 1
    GL343215.1(1526247-1551938)
    zebrafish
    (Danio rerio)
    Actinopterygii rufy21 RUN and FYVE domain containing 2 71.58(n)
    79.23(a)
      569096  NM_001105681.1  NP_001099151.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG310641 CG31064 51.26(n)
    46.75(a)
      43277  NM_170324.2  NP_733203.1 


    ENSEMBL Gene Tree for RUFY2 (if available)
    TreeFam Gene Tree for RUFY2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RUFY2 gene
    RUNDC3A2  RUFY32  RUNDC3B2  RUFY12  
    3 SIMAP similar genes for RUFY2 using alignment to 6 protein entries:     RUFY2_HUMAN (see all proteins):
    RUFY3    RUFY1    RUNDC3A

    RUFY2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1324 SNPs in RUFY2 are shown (see all 1324)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs172974391,2
    C,F,H--70103461(+) ATCACG/AAAATA 1 -- ut3121Minor allele frequency- A:0.10NA NS EA WA 2482
    rs1848425451,2
    --70103477(+) TGTTAA/GAAGTC 1 -- ut310--------
    rs1904177441,2
    C--70103497(+) AAAAAC/TCCAAA 1 -- ut310--------
    rs1484363431,2
    C--70103501(+) TCCAA-/AGTT  
            
    AGTTA
    1 -- ut310--------
    rs1482160391,2
    --70103508(+) GTTAGA/TATAGT 1 -- ut310--------
    rs1397899201,2
    C--70103564(+) CTGCC-/TTAAAA 1 -- ut310--------
    rs11627551,2
    C,F,A,H--70103566(-) TTTTTA/TAGGCA 1 -- ut315Minor allele frequency- T:0.17NA WA 12
    rs348117011,2
    F--70103590(+) AAAAAG/AGCAAG 1 -- ut311Minor allele frequency- A:0.50NA 4
    rs11627541,2
    C,F,H--70103597(-) TGACTT/GACTTG 1 -- ut3116Minor allele frequency- G:0.01MN NS EA NA WA CSA 957
    rs1412182571,2
    C--70103616(+) ACATGA/GGTTTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for RUFY2 (70100864 - 70167051 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for RUFY2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2670140CNV Deletion23128226
    nsv6988CNV Insertion18451855
    nsv895691CNV Loss21882294
    nsv895690CNV Loss21882294
    nsv895692CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610328    OMIM disorders: --

    2 diseases for RUFY2:    About MalaCards
    alzheimer's disease    


    RUFY2 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): RUFY2
    Human Genome Epidemiology (HuGE) Navigator: RUFY2 (1 document)

    Export disorders for RUFY2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RUFY2 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with RUFY2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Interaction between tyrosine kinase Etk and a RUN-domain and FYVE- domain containing protein RUFY1. A possible role of Etk in regulation of vesicle trafficking. (PubMed id 11877430)1, 2, 3 Yang J.... Qiu Y. (2002)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    5. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2 Nagase T.... Ohara O. (2000)
    6. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    9. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55680 HGNC: 19761 AceView: RUFY2 Ensembl:ENSG00000204130 euGenes: HUgn55680
    ECgene: RUFY2 H-InvDB: RUFY2

    (According to HUGE)
    About This Section
    HUGE: KIAA1537

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RUFY2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RUFY2 gene:
    Search GeneIP for patents involving RUFY2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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