Aliases for RUBCNL Gene
External Ids for RUBCNL Gene
Previous HGNC Symbols for RUBCNL Gene
This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients. [provided by RefSeq, Mar 2017]
GeneCards Summary for RUBCNL Gene
RUBCNL (RUN And Cysteine Rich Domain Containing Beclin 1 Interacting Protein Like) is a Protein Coding gene. An important paralog of this gene is RUBCN.
UniProtKB/Swiss-Prot for RUBCNL Gene
May act as a tumor suppressor.