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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RTN4RL1 Gene

protein-coding GIFtS: 50
GCID: GC17M001786

reticulon 4 receptor-like 1

Explore 1 disease affiliated with
RTN4RL1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Reticulon 4 Receptor-Like 1¹ ²		Nogo-66 Receptor-Related Protein 3² ³
NGRH2¹ ² ³		DKFZp547J144¹
NgR3¹ ² ³		Reticulon-4 Receptor-Like 1²
Nogo Receptor-Like 2² ³		NGRL2³
Nogo-66 Receptor Homolog 2² ³

External Ids:	HGNC: 21329¹	Entrez Gene: 146760²	Ensembl: ENSG00000185924⁷	OMIM: 610461⁵	UniProtKB: Q86UN2³

Export aliases for RTN4RL1 gene to outside databases

Previous GC identifers: GC17M002046 GC17M001734

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: R4RL1_HUMAN, Q86UN2

Function: May play a role in regulating axonal regeneration and plasticity in the adult central nervous system

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NC_018928.1 NT_010718.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RTN4RL1 gene promoter:
c-Fos Max1 NF-1 NCX/Ncx SREBP-1c SREBP-1b GATA-2 SREBP-1a Chx10 c-Myc
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RTN4RL1 promoter sequence

Search SABiosciences Chromatin IP Primers for RTN4RL1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RTN4RL1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.3 Ensembl cytogenetic band: 17p13.3 HGNC cytogenetic band: 17p13.3

RTN4RL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RTN4RL1 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M001786: view genomic region (about GC identifiers)

Start:	1,837,971 bp from pter	End:	1,928,178 bp from pter
Size:	90,208 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: R4RL1_HUMAN, Q86UN2 (See protein sequence)

Recommended Name: Reticulon-4 receptor-like 1 precursor

Size: 441 amino acids; 49065 Da

Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor. Note=Localized to the surface of neurons, including

axons

Secondary accessions: A1A5E3 Q8ND46

Explore the universe of human proteins at neXtProt for RTN4RL1: NX_Q86UN2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q86UN2

RTN4RL1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_848663.1

ENSEMBL proteins:

ENSP00000330631

Human Recombinant Protein Products for RTN4RL1:

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	Uscn Proteins for RTN4RL1

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0009897	external side of plasma membrane	IEA	--
GO:0009986	cell surface	IDA	--
GO:0045121	membrane raft	IEA	--
GO:0046658	anchored to plasma membrane	IDA	12694398

RTN4RL1 for ontologies About GeneDecksing

RTN4RL1 Antibody Products:

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	Uscn ELISAs and CLIAs for RTN4RL1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RTN4RL1 for domains About GeneDecksing

4 InterPro domains/families:

IPR000483 Cys-rich_flank_reg_C

IPR000372 LRR-contain_N

IPR001611 Leu-rich_rpt

IPR003591 Leu-rich_rpt_typical-subtyp

Graphical View of Domain Structure for InterPro Entry Q86UN2

ProtoNet protein and cluster: Q86UN2

2 Blocks protein families:

IPB000372 Cysteine-rich flanking region

IPB000483 Cysteine-rich flanking region

UniProtKB/Swiss-Prot: R4RL1_HUMAN, Q86UN2

Similarity: Belongs to the Nogo receptor family

Similarity: Contains 8 LRR (leucine-rich) repeats

Similarity: Contains 1 LRRCT domain

Similarity: Contains 1 LRRNT domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: R4RL1_HUMAN, Q86UN2

Function: May play a role in regulating axonal regeneration and plasticity in the adult central nervous system

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004872	receptor activity	IDA	12694398

RTN4RL1 for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for RTN4RL1:

Decreased G3BP1 protein expres

Decreased Salmonella enterica

3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Rtn4rl1):

endocrine/exocrine gland

liver/biliary system

nervous system

RTN4RL1 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RTN4RL1

miRNA Products:		OriGene 3'-UTR Clone: RTN4RL1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RTN4RL1
		8/26 QIAGEN miScript miRNA Assays for microRNAs that regulate RTN4RL1 (see all 26):
		hsa-miR-448 hsa-miR-200a hsa-miR-4305 hsa-miR-374a hsa-miR-500a hsa-miR-340 hsa-miR-410 hsa-miR-449a

		SwitchGear 3'UTR luciferase reporter plasmid: RTN4RL1 3' UTR sequence

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Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RTN4RL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RTN4RL1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RTN4RL1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RTN4RL1

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for RTN4RL1 (Q86UN2³ ENSP00000330631⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
OMG	P23515³, ENSP00000247271⁴	I2D: score=1 STRING: ENSP00000247271

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0031103	axon regeneration	TAS	14664809

RTN4RL1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RTN4RL1
Search CenterWatch for drugs/clinical trials and news about RTN4RL1 / R4RL1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RTN4RL1 gene:

NM_178568.2

Unigene Cluster for RTN4RL1:

Reticulon 4 receptor-like 1

Hs.22917 [show with all ESTs]

Unigene Representative Sequence: NM_178568

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000331238(uc002ftp.3)

miRNA Products:		OriGene 3'-UTR Clone: RTN4RL1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RTN4RL1
		8/26 QIAGEN miScript miRNA Assays for microRNAs that regulate RTN4RL1 (see all 26):
		hsa-miR-448 hsa-miR-200a hsa-miR-4305 hsa-miR-374a hsa-miR-500a hsa-miR-340 hsa-miR-410 hsa-miR-449a

		SwitchGear 3'UTR luciferase reporter plasmid: RTN4RL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		Sirion Biotech Custom design and validation of potent shRNA sequences against RTN4RL1

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		GenScript: all cDNA clones in your preferred vector: RTN4RL1 (NM_178568)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RTN4RL1
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RTN4RL1

Additional cDNA sequence:

AF532859.1 AL834409.1 AY250219.1 BC023311.1 BC128608.1

1 DOTS entry:

DT.111911

24/43 AceView cDNA sequences (see all 43):

CA429077 BM692581 BM826920 BQ445827 BU618906 R20190 BM976284 BU740371

AA453794 AF532859 AY250219 BQ771530 AI278851 BM709737 BM680479 BC023311

AI693887 BK001305 BM663803 CA454639 NM_178568 AL834409 AI680692 BM718025

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RTN4RL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

RTN4RL1 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Inner Nuclear Layer

Type1 Off Cone Bipolar Cells

Bipolar, Retina

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See RTN4RL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RTN4RL1

SOURCE GeneReport for Unigene cluster: Hs.22917

UniProtKB/Swiss-Prot: R4RL1_HUMAN, Q86UN2

Tissue specificity: Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland,

placenta, salivary gland, skeletal muscle and spleen

SABiosciences Custom PCR Arrays for RTN4RL1

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for RTN4RL1 gene from 3/13 species (see all 13) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	RTN4RL1¹	reticulon 4 receptor-like 1	74.28(n) 74.13(a)		427828 XM_425402.3 XP_425402.3
lizard (Anolis carolinensis)	Reptilia	RTN4RL1⁶	--	60(a)	1 ↔ 1	GL343393.1(4196-5458)
zebrafish (Danio rerio)	Actinopterygii	rtn4rl1b¹	reticulon 4 receptor-like 1b	62.11(n) 61.15(a)		403308 NM_203480.1 NP_982347.1

ENSEMBL Gene Tree for RTN4RL1 (if available)
TreeFam Gene Tree for RTN4RL1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RTN4RL1 gene

NYX² LRRC53² RTN4R² LRRC70² RTN4RL2²

2 SIMAP similar genes for RTN4RL1 using alignment to 1 protein entry: R4RL1_HUMAN:

RTN4RL2 RTN4R

RTN4RL1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs150501705^1,2		--	1837492(+)	`GAGACA/GTGTGC`	1	--	int¹		0	--	--	--	--
rs8080549^1,2	C,F,A,H	--	1837525(+)	`TGTCCG/TGGTGG`	1	--	int¹		12		NA EA WA CSA	732
rs8080578^1,2	C,F,A,H	--	1837606(+)	`CAGCCG/ACCTGC`	1	--	int¹		8		NA WA CSA EA	370
rs191172228^1,2		--	1837613(+)	`CTGCCA/GGGCGC`	1	--	int¹		0	--	--	--	--
rs183076471^1,2		--	1837696(+)	`TCCTCC/TGGGGA`	1	--	int¹		0	--	--	--	--
rs149688823^1,2		--	1837732(+)	`GGGCAG/TTCAGA`	1	--	int¹		0	--	--	--	--
rs187071580^1,2		--	1837756(+)	`ATCATC/GATCTG`	1	--	int¹		0	--	--	--	--
rs190386260^1,2		--	1837764(+)	`CTGTGC/TGGGCA`	1	--	int¹		0	--	--	--	--
rs144516741^1,2		--	1837785(+)	`CACGAA/GACGGA`	1	--	int¹		0	--	--	--	--
rs140918392^1,2		--	1837787(+)	`CGAAAC/TGGAGC`	1	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for RTN4RL1 (1837971 - 1928178 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for RTN4RL1
4 CNVs: 102382 67104 7142 72767
1 Indel: 45512
Human Gene Mutation Database (HGMD): RTN4RL1

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RTN4RL1

DNA2.0 Custom Variant and Variant Library Synthesis for RTN4RL1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RTN4RL1 for disorders           About GeneDecksing

OMIM gene information: 610461    OMIM disorders: --

1 disease for RTN4RL1:    About MalaCards

neuronitis

Export disorders for RTN4RL1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RTN4RL1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RTN4RL1)

Utopia: connect your pdf to the dynamic
world of online information

Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins. (PubMed id 12839991)^{1, 2, 9} Barton W.A.... Nikolov D.B. (2003)
Two novel mammalian nogo receptor homologs differentially expressed in the central and peripheral nervous systems. (PubMed id 14664809)^{1, 2, 9} Lauren J.... Timmusk T. (2003)
Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo-66 receptor. (PubMed id 12694398)^{1, 2} Pignot V.... Frentzel S. (2003)
Nogo receptor 3, a paralog of Nogo-66 receptor 1 (NgR1 ), may function as a NgR1 co-receptor for Nogo-66. (PubMed id 22133682)¹ Zhang L....Zhang J. (2011)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. (PubMed id 12068310)¹ Wang K.C....He Z. (2002)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 146760	HGNC: 21329	AceView: RTN4RL1	Ensembl:ENSG00000185924	euGenes: HUgn146760
ECgene: RTN4RL1	H-InvDB: RTN4RL1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for RTN4RL1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RTN4RL1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for RTN4RL1 gene:
Search GeneIP for patents involving RTN4RL1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	EMD Millipore Custom Antibody & Bulk Services
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	Antibodies for RTN4RL1 (NgR3/NgRH2)		Browse Cell Culture Products
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	Browse OriGene Antibodies		OriGene shRNA RFP for RTN4RL1
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RTN4RL1		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RTN4RL1
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	OriGene siRNA for RTN4RL1		OriGene 3'-UTR Clone for RTN4RL1
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RTN4RL1
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	GenScript Custom Purified and Recombinant Proteins Services for RTN4RL1		GenScript cDNA clones with any tag delivered in your preferred vector for RTN4RL1
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	Regulatory tfbs in RTN4RL1 promoter
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	SABiosciences Custom PCR Arrays for RTN4RL1

Search Tocris compounds for RTN4RL1

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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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Browse ProSpec Recombinant Proteins

RTN4RL1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for RTN4RL1

	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RTN4RL1

	SwitchGear 3'UTR luciferase reporter plasmids for RTN4RL1
	SwitchGear Promoter luciferase reporter plasmids for RTN4RL1

ThermoFisher Antibody for RTN4RL1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RTN4RL1

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RTN4RL1

Sirion Biotech Customized:

	stable knockdown cell line services for RTN4RL1
	inducible knockdown cell line services for RTN4RL1
	design and validation of potent shRNA sequences against RTN4RL1
	adenovirus for potent knockdown of RTN4RL1
	adenovirus for overexpression of RTN4RL1
	stable overexpressing cell line services for RTN4RL1
	inducible overexpressing cell line services for RTN4RL1

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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RTN4RL1 Gene

reticulon 4 receptor-like 1

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RTN4RL1 Gene

reticulon 4 receptor-like 1

Aliasesfor RTN4RL1 gene

Summariesfor RTN4RL1 gene

Genomic Viewsfor RTN4RL1 gene

Proteinsfor RTN4RL1 gene

Protein Domains /Familiesfor RTN4RL1 gene

Functionfor RTN4RL1 gene

Pathways & Interactionsfor RTN4RL1 gene

Drugs & Compoundsfor RTN4RL1 gene

Transcriptsfor RTN4RL1 gene

Expression for RTN4RL1 gene

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Paralogsfor RTN4RL1 gene

Genomic Variantsfor RTN4RL1 gene

Disorders / Diseasesfor RTN4RL1 gene

Publicationsfor RTN4RL1 gene

External Searches for RTN4RL1 gene

Genome Databases showing RTN4RL1 gene

Other Databases showing RTN4RL1 gene

Specialized Databases showing RTN4RL1 gene

Intellectual Propertyfor RTN4RL1 gene

Productsfor RTN4RL1 gene

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Aliases
for RTN4RL1 gene

Summaries
for RTN4RL1 gene

Genomic Views
for RTN4RL1 gene

Proteins
for RTN4RL1 gene

Protein Domains /
Families
for RTN4RL1 gene

Function
for RTN4RL1 gene

Pathways & Interactions
for RTN4RL1 gene

Drugs & Compounds
for RTN4RL1 gene

Transcripts
for RTN4RL1 gene

Expression
for RTN4RL1 gene

Orthologs
for RTN4RL1 gene

Paralogs
for RTN4RL1 gene

Genomic Variants
for RTN4RL1 gene

Disorders / Diseases
for RTN4RL1 gene

Publications
for RTN4RL1 gene

Intellectual Property
for RTN4RL1 gene

Products
for RTN4RL1 gene