Aliases for RTN4R Gene
External Ids for RTN4R Gene
Previous GeneCards Identifiers for RTN4R Gene
This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. [provided by RefSeq, Jul 2008]
GeneCards Summary for RTN4R Gene
RTN4R (Reticulon 4 Receptor) is a Protein Coding gene. Diseases associated with RTN4R include Schizophrenia and Spinal Cord Injury. Among its related pathways are Spinal Cord Injury and Guidance Cues and Growth Cone Motility. GO annotations related to this gene include receptor activity. An important paralog of this gene is TPBGL.
UniProtKB/Swiss-Prot for RTN4R Gene
Receptor for RTN4, OMG and MAG. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LINGO1 in regulating neuronal precursor cell motility during cortical development.