Aliases for RTN4IP1 Gene
External Ids for RTN4IP1 Gene
Previous GeneCards Identifiers for RTN4IP1 Gene
This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, mental retardation, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
GeneCards Summary for RTN4IP1 Gene
RTN4IP1 (Reticulon 4 Interacting Protein 1) is a Protein Coding gene. Diseases associated with RTN4IP1 include Spinal Cord Injury. GO annotations related to this gene include oxidoreductase activity and transferase activity, transferring acyl groups other than amino-acyl groups. An important paralog of this gene is CRYZ.
UniProtKB/Swiss-Prot for RTN4IP1 Gene
Appears to be a potent inhibitor of regeneration following spinal cord injury.