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Aliases for RTN4 Gene

Aliases for RTN4 Gene

  • Reticulon 4 2 3 5
  • Neuroendocrine-Specific Protein C Homolog 3 4
  • Neurite Outgrowth Inhibitor 3 4
  • Foocen 3 4
  • RTN-X 3 4
  • NOGO 3 4
  • NSP 3 4
  • Neuroendocrine-Specific Protein 4
  • Neurite Growth Inhibitor 220 3
  • My043 Protein 3
  • Nogo Protein 4
  • Human NogoA 3
  • Reticulon 5 3
  • Reticulon-4 3
  • Reticulon-5 4
  • NI220/250 3
  • Nbla00271 3
  • Nbla10545 3
  • KIAA0886 4
  • RTN4-B1 3
  • RTN4-B2 3
  • NSP-CL 3
  • RTN4-A 3
  • RTN4-C 3
  • ASY 3

External Ids for RTN4 Gene

Previous GeneCards Identifiers for RTN4 Gene

  • GC02M055237
  • GC02M055386
  • GC02M055173
  • GC02M055110
  • GC02M055199

Summaries for RTN4 Gene

Entrez Gene Summary for RTN4 Gene

  • This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

GeneCards Summary for RTN4 Gene

RTN4 (Reticulon 4) is a Protein Coding gene. Diseases associated with RTN4 include Demyelinating Disease and Pedophilia. Among its related pathways are p75 NTR receptor-mediated signalling and Spinal Cord Injury. An important paralog of this gene is RTN1.

UniProtKB/Swiss-Prot for RTN4 Gene

  • Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex (By similarity). Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing. Induces the formation and stabilization of endoplasmic reticulum (ER) tubules (PubMed:25612671, PubMed:24262037, PubMed:27619977). Regulates membrane morphogenesis in the ER by promoting tubular ER production (PubMed:27619977). Influences NE expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins (PubMed:26906412).

Gene Wiki entry for RTN4 Gene

Additional gene information for RTN4 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RTN4 Gene

Genomics for RTN4 Gene

GeneHancer (GH) Regulatory Elements for RTN4 Gene

Promoters and enhancers for RTN4 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I055045 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 583.6 +63.2 63181 8.2 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ZNF263 SP3 RTN4 RPS27A PRORSD1P RNU6-433P ENSG00000272156 CLHC1 EML6 GC02P055039 LOC105374662
GH02I055005 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 590.1 +102.7 102657 8.2 HDGF FOXA2 ATF1 ARNT ZFP64 ZSCAN4 FEZF1 RAD21 RFX5 YY1 RTN4 CLHC1 GC02M055015 GC02M054976
GH02I054975 Enhancer 1 Ensembl ENCODE dbSUPER 44 +135.6 135571 2.2 PKNOX1 JUNB ELF1 ATF2 IKZF1 NBN ETV6 IKZF2 BCLAF1 SPI1 GC02M054976 RTN4 EML6 GC02M055015
GH02I055133 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 26.8 -21.5 -21529 2.1 PKNOX1 ATF1 FOXA2 ARNT YY1 NCOA2 ZNF766 RUNX3 RXRA CAVIN1 RTN4 CLHC1 RNU6-433P PPP4R3B CCDC88A GC02P055128 GC02M055160
GH02I054954 Enhancer 1.3 Ensembl ENCODE dbSUPER 32.5 +156.6 156635 2.3 FOXA2 CLOCK ATF1 YY1 TCF12 POLR2B ZNF766 GATA2 CAVIN1 NCOA1 RTN4 CLHC1 GC02P054967 GC02P054931 EML6
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RTN4 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RTN4 gene promoter:

Genomic Locations for RTN4 Gene

Genomic Locations for RTN4 Gene
chr2:54,972,187-55,112,621
(GRCh38/hg38)
Size:
140,435 bases
Orientation:
Minus strand
chr2:55,199,325-55,339,757
(GRCh37/hg19)

Genomic View for RTN4 Gene

Genes around RTN4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RTN4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RTN4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RTN4 Gene

Proteins for RTN4 Gene

  • Protein details for RTN4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NQC3-RTN4_HUMAN
    Recommended name:
    Reticulon-4
    Protein Accession:
    Q9NQC3
    Secondary Accessions:
    • O94962
    • Q7L7Q5
    • Q7L7Q6
    • Q7L7Q8
    • Q8IUA4
    • Q96B16
    • Q9BXG5
    • Q9H212
    • Q9H3I3
    • Q9UQ42
    • Q9Y293
    • Q9Y2Y7
    • Q9Y5U6

    Protein attributes for RTN4 Gene

    Size:
    1192 amino acids
    Molecular mass:
    129931 Da
    Quaternary structure:
    • Binds to RTN4R. Interacts with Bcl-xl and Bcl-2. Isoform 2 binds to NGBR and RTN3. Isoform 2 and isoform 3 interact with BACE1 and BACE2. Interacts with RTN4IP1. Interacts with ATL1. Interacts with TMEM170A (PubMed:26906412). Isoform 3 interacts with TMEM33 (PubMed:25612671).
    SequenceCaution:
    • Sequence=AAD39920.1; Type=Frameshift; Positions=1149, 1156; Evidence={ECO:0000305}; Sequence=AAG43160.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAG43160.1; Type=Frameshift; Positions=684, 700; Evidence={ECO:0000305}; Sequence=BAA74909.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for RTN4 Gene

    Alternative splice isoforms for RTN4 Gene

neXtProt entry for RTN4 Gene

Post-translational modifications for RTN4 Gene

  • Ubiquitination at posLast=10901090 and isoforms=2, 3, 4, 5, 61171

No data available for DME Specific Peptides for RTN4 Gene

Domains & Families for RTN4 Gene

Gene Families for RTN4 Gene

Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for RTN4 Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q9NQC3

UniProtKB/Swiss-Prot:

RTN4_HUMAN :
  • Three regions, residues 59-172, 544-725 and the loop 66 amino acids, between the two transmembrane domains, known as Nogo-66 loop, appear to be responsible for the inhibitory effect on neurite outgrowth and the spreading of neurons. This Nogo-66 loop, mediates also the binding of RTN4 to its receptor (By similarity).
Domain:
  • Three regions, residues 59-172, 544-725 and the loop 66 amino acids, between the two transmembrane domains, known as Nogo-66 loop, appear to be responsible for the inhibitory effect on neurite outgrowth and the spreading of neurons. This Nogo-66 loop, mediates also the binding of RTN4 to its receptor (By similarity).
genes like me logo Genes that share domains with RTN4: view

Function for RTN4 Gene

Molecular function for RTN4 Gene

UniProtKB/Swiss-Prot Function:
Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex (By similarity). Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing. Induces the formation and stabilization of endoplasmic reticulum (ER) tubules (PubMed:25612671, PubMed:24262037, PubMed:27619977). Regulates membrane morphogenesis in the ER by promoting tubular ER production (PubMed:27619977). Influences NE expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins (PubMed:26906412).

Phenotypes From GWAS Catalog for RTN4 Gene

Gene Ontology (GO) - Molecular Function for RTN4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding HDA 22658674
GO:0005515 protein binding IPI 11126360
GO:0031625 ubiquitin protein ligase binding IPI 27353365
GO:0045296 cadherin binding IDA 25468996
genes like me logo Genes that share ontologies with RTN4: view
genes like me logo Genes that share phenotypes with RTN4: view

Animal Models for RTN4 Gene

MGI Knock Outs for RTN4:

Animal Model Products

CRISPR Products

Clone Products

  • Addgene plasmids for RTN4

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RTN4 Gene

Localization for RTN4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RTN4 Gene

Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Anchored to the membrane of the endoplasmic reticulum (ER) through 2 putative transmembrane domains. Localizes throughout the ER tubular network (PubMed:27619977). Co-localizes with TMEM33 at the ER sheets. {ECO:0000269 PubMed:25612671, ECO:0000269 PubMed:27619977}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RTN4 gene
Compartment Confidence
plasma membrane 5
extracellular 5
nucleus 5
endoplasmic reticulum 5
cytoskeleton 2
cytosol 2
mitochondrion 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for RTN4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IMP 14644040
GO:0005635 nuclear envelope IDA 11126360
GO:0005783 endoplasmic reticulum IEA,NAS 11126360
GO:0005789 endoplasmic reticulum membrane IEA,IDA 25612671
GO:0005886 plasma membrane TAS --
genes like me logo Genes that share ontologies with RTN4: view

Pathways & Interactions for RTN4 Gene

genes like me logo Genes that share pathways with RTN4: view

Pathways by source for RTN4 Gene

1 KEGG pathway for RTN4 Gene
1 GeneGo (Thomson Reuters) pathway for RTN4 Gene
1 Qiagen pathway for RTN4 Gene

SIGNOR curated interactions for RTN4 Gene

Activates:
Other effect:

Gene Ontology (GO) - Biological Process for RTN4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006915 apoptotic process NAS 11126360
GO:0007399 nervous system development IEA --
GO:0007413 axonal fasciculation IBA,ISS --
GO:0010634 positive regulation of epithelial cell migration IMP 27353365
GO:0021801 cerebral cortex radial glia guided migration ISS --
genes like me logo Genes that share ontologies with RTN4: view

Drugs & Compounds for RTN4 Gene

(1) Additional Compounds for RTN4 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with RTN4: view

Transcripts for RTN4 Gene

Unigene Clusters for RTN4 Gene

Reticulon 4:
Representative Sequences:

CRISPR Products

Clone Products

  • Addgene plasmids for RTN4

Alternative Splicing Database (ASD) splice patterns (SP) for RTN4 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15a · 15b · 15c · 15d ^ 16 ^
SP1: - - - - - - - - - - - - - - - -
SP2: - - - - - - - - - - - - -
SP3: - - - - - - - - - - -
SP4: - - - - - - - - -
SP5: - - - - - - - -
SP6: - - - - - - -
SP7: - - - - - -
SP8: - - - - - - - - - - - -
SP9: - - - - - - - - - - - - -
SP10: - - - - - - - - - - -
SP11: - - - -
SP12: - - -
SP13: - - - - -
SP14: - - - - - -
SP15: - -
SP16:
SP17:
SP18:

ExUns: 17a · 17b · 17c · 17d
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:

Relevant External Links for RTN4 Gene

GeneLoc Exon Structure for
RTN4
ECgene alternative splicing isoforms for
RTN4

Expression for RTN4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RTN4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RTN4 Gene



Protein tissue co-expression partners for RTN4 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of RTN4 Gene:

RTN4

SOURCE GeneReport for Unigene cluster for RTN4 Gene:

Hs.637850

mRNA Expression by UniProt/SwissProt for RTN4 Gene:

Q9NQC3-RTN4_HUMAN
Tissue specificity: Isoform 1 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 is widely expressed except for the liver. Isoform 3 is expressed in brain, skeletal muscle and adipocytes. Isoform 4 is testis-specific.

Evidence on tissue expression from TISSUES for RTN4 Gene

  • Muscle(5)
  • Nervous system(5)
  • Liver(4.7)
  • Blood(4.5)
  • Skin(4.5)
  • Eye(4.4)
  • Kidney(4.3)
  • Lung(4.3)
  • Pancreas(4.1)
  • Heart(2.8)
  • Adrenal gland(2.6)
  • Intestine(2.4)
  • Bone(2.2)
  • Gall bladder(2.1)
genes like me logo Genes that share expression patterns with RTN4: view

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for RTN4 Gene

Orthologs for RTN4 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RTN4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RTN4 34
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RTN4 33 34
  • 91 (n)
dog
(Canis familiaris)
Mammalia RTN4 33 34
  • 88.51 (n)
mouse
(Mus musculus)
Mammalia Rtn4 33 16 34
  • 83.56 (n)
rat
(Rattus norvegicus)
Mammalia Rtn4 33
  • 83.28 (n)
oppossum
(Monodelphis domestica)
Mammalia RTN4 34
  • 69 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RTN4 34
  • 65 (a)
OneToOne
chicken
(Gallus gallus)
Aves RTN4 34
  • 73 (a)
OneToOne
LOC101749579 33
  • 60.49 (n)
lizard
(Anolis carolinensis)
Reptilia RTN4 34
  • 45 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia rtn4 33
  • 58.06 (n)
Str.386 33
African clawed frog
(Xenopus laevis)
Amphibia MGC68489 33
zebrafish
(Danio rerio)
Actinopterygii rtn4a 34
  • 51 (a)
OneToOne
Dr.24718 33
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.8546 33
fruit fly
(Drosophila melanogaster)
Insecta Rtnl1 34
  • 27 (a)
ManyToMany
Rtnl2 34
  • 22 (a)
ManyToMany
CG42853 34
  • 18 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea ret-1 34
  • 7 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RTN2 36
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10170 34
  • 33 (a)
OneToMany
Species where no ortholog for RTN4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RTN4 Gene

ENSEMBL:
Gene Tree for RTN4 (if available)
TreeFam:
Gene Tree for RTN4 (if available)

Paralogs for RTN4 Gene

Paralogs for RTN4 Gene

genes like me logo Genes that share paralogs with RTN4: view

Variants for RTN4 Gene

Sequence variations from dbSNP and Humsavar for RTN4 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
VAR_035904 A colorectal cancer sample p.Leu429Val
rs1000037017 -- 54,975,267(-) A/C intron_variant
rs1000041744 -- 55,118,021(-) G/A genic_upstream_transcript_variant, intron_variant
rs1000052566 -- 55,081,909(-) C/T genic_upstream_transcript_variant, intron_variant
rs1000064918 -- 55,035,168(-) A/G genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for RTN4 Gene

Variant ID Type Subtype PubMed ID
esv2474783 CNV deletion 19546169
esv2517082 CNV deletion 19546169
esv2720078 CNV deletion 23290073
esv3340657 CNV insertion 20981092
nsv582029 CNV loss 21841781
nsv834069 CNV loss 17160897
nsv953127 CNV duplication 24416366

Variation tolerance for RTN4 Gene

Residual Variation Intolerance Score: 35.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.11; 80.53% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RTN4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RTN4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RTN4 Gene

Disorders for RTN4 Gene

MalaCards: The human disease database

(15) MalaCards diseases for RTN4 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
demyelinating disease
  • demyelinating disorder
pedophilia
  • paedophilia
alzheimer disease
  • ad
disease of mental health
  • mental health
amyotrophic lateral sclerosis 1
  • als1
- elite association - COSMIC cancer census association via MalaCards
Search RTN4 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for RTN4

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with RTN4: view

No data available for UniProtKB/Swiss-Prot and Genatlas for RTN4 Gene

Publications for RTN4 Gene

  1. Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein. (PMID: 10667797) GrandPré T … Strittmatter SM (Nature 2000) 2 3 4 22 58
  2. The association between dilated cardiomyopathy and RTN4 3'UTR insertion/deletion polymorphisms. (PMID: 18948092) Zhou B … Zhang L (Clinica chimica acta; international journal of clinical chemistry 2009) 3 22 44 58
  3. Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells. (PMID: 16835300) Miao RQ … Sessa WC (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 4 22 58
  4. CAA insertion polymorphism in the 3'UTR of Nogo gene on 2p14 is not associated with schizophrenia. (PMID: 15661375) Xiong L … Joober R (Brain research. Molecular brain research 2005) 3 22 44 58
  5. Nogo CAA 3'UTR Insertion polymorphism is not associated with Schizophrenia nor with bipolar disorder. (PMID: 15820318) Gregório SP … Dias-Neto E (Schizophrenia research 2005) 3 22 44 58

Products for RTN4 Gene

Sources for RTN4 Gene

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