Aliases for RSRP1 Gene
Aliases for RSRP1 Gene
External Ids for RSRP1 Gene
- HGNC: 25234
- Entrez Gene: 57035
- Ensembl: ENSG00000117616
- UniProtKB: Q9BUV0
Previous HGNC Symbols for RSRP1 Gene
- C1orf63
Previous GeneCards Identifiers for RSRP1 Gene
- GC01M025569
Summaries for RSRP1 Gene
GeneCards Summary for RSRP1 Gene
RSRP1 (Arginine And Serine Rich Protein 1) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RSRP1 Gene
Genomics for RSRP1 Gene
GeneHancer (GH) Regulatory Elements for RSRP1 Gene
Promoters and enhancers for RSRP1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around RSRP1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for RSRP1 Gene
Genomic Locations for RSRP1 Gene
- chr1:25,242,237-25,338,213
- (GRCh38/hg38)
- Size:
- 95,977 bases
- Orientation:
- Minus strand
- chr1:25,568,728-25,664,704
- (GRCh37/hg19)
Genomic View for RSRP1 Gene
Genes around RSRP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.11 by Ensembl
- 1p36.11 by Entrez Gene
- 1p36.11 by HGNC
RSRP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RSRP1 Gene
Proteins for RSRP1 Gene
-
Protein details for RSRP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BUV0-RSRP1_HUMAN
- Recommended name:
- Arginine/serine-rich protein 1
- Protein Accession:
- Q9BUV0
- A8K917
- Q49AA4
- Q5TH71
- Q9GZP6
Protein attributes for RSRP1 Gene
- Size:
- 290 amino acids
- Molecular mass:
- 33613 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for RSRP1 Gene
- Ubiquitination at isoforms=2, 3188
Other Protein References for RSRP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for RSRP1
- Novus Biologicals Antibodies for RSRP1
- Invitrogen Antibodies for RSRP1
- GeneTex RSRP1 antibody for RSRP1
Protein Products
-
OriGene Purified Proteins for RSRP1
- Search Origene for MassSpec and Protein Over-expression Lysates for RSRP1
- Origene Custom Protein Services for RSRP1
- Novus Biologicals proteins for RSRP1
- Search GeneTex for Proteins for RSRP1
Assay Products
No data available for DME Specific Peptides for RSRP1 Gene
Domains & Families for RSRP1 Gene
Gene Families for RSRP1 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for RSRP1 Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for RSRP1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9BUV0- Family:
-
- Belongs to the RSRP family.
Function for RSRP1 Gene
Phenotypes From GWAS Catalog for RSRP1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16189514 |
Phenotypes for RSRP1 Gene
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for RSRP1 gene
-
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CRISPR Products
-
OriGene CRISPR knockouts for RSRP1
- genomics-online: gRNA clones - Search results for 38 available C1orf63 gene related products
- Overview of 38 available C1orf63 gene related products
- Applied Biological Materials CRISPR for RSRP1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RSRP1
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miRNA for RSRP1 Gene
- miRTarBase miRNAs that target RSRP1
miRNA Products
- Search ViGene Biosciences for RSRP1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for RSRP1
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- genomics-online: shRNA clones - Search results for 38 available C1orf63 gene related products
- Overview of 38 available C1orf63 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for RSRP1 gene
Clone Products
- Sino Biological Human cDNA Clone for RSRP1
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RSRP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for RSRP1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for RSRP1
-
ViGene Biosciences adenoviral particle packaged cDNA for RSRP1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for RSRP1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RSRP1 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RSRP1 Gene
Localization for RSRP1 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 1 |
- Nucleoplasm (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RSRP1 Gene
Pathways & Interactions for RSRP1 Gene
No Data Available
Interacting Proteins for RSRP1 Gene
Selected Interacting proteins:
Q9BUV0-RSRP1_HUMAN
ENSP00000243189
for RSRP1 Gene via
IID
UniProtKB
STRING
MINT
No data available for Pathways by source and SIGNOR curated interactions for RSRP1 Gene
Transcripts for RSRP1 Gene
mRNA/cDNA for RSRP1 Gene
- (3) REFSEQ mRNAs :
- (414) Selected AceView cDNA sequences:
- (22) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for RSRP1
- genomics-online: gRNA clones - Search results for 38 available C1orf63 gene related products
- Overview of 38 available C1orf63 gene related products
- Applied Biological Materials CRISPR for RSRP1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RSRP1
- GenScript: Design CRISPR guide RNA sequences for RSRP1
miRNA Products
- Search ViGene Biosciences for RSRP1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for RSRP1
- Browse OriGene Inhibitory RNA Products For RSRP1
- genomics-online: shRNA clones - Search results for 38 available C1orf63 gene related products
- Overview of 38 available C1orf63 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for RSRP1 gene
Clone Products
- Sino Biological Human cDNA Clone for RSRP1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RSRP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RSRP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for RSRP1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: |
Expression for RSRP1 Gene
NURSA nuclear receptor signaling pathways regulating expression of RSRP1 Gene:
RSRP1Evidence on tissue expression from TISSUES for RSRP1 Gene
- Nervous system(4.7)
- Lung(3.7)
- Intestine(2.4)
Primer Products
-
OriGene qPCR primer pairs for RSRP1
-
OriGene qPCR primer pairs and template standards for RSRP1
- genomics-online: primer clones - Search results for 38 available C1orf63 gene related products
- Overview of 38 available C1orf63 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RSRP1 Gene
Orthologs for RSRP1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C1ORF63 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | D4Wsu53e 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | C1orf63 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | C1orf63 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | C1orf63 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany |
- Species where no ortholog for RSRP1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for RSRP1 Gene
No data available for Paralogs for RSRP1 Gene
Variants for RSRP1 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1053355 | not-provided, Weak RhD expression | 25,301,061(-) | C/G | genic_downstream_transcript_variant, genic_upstream_transcript_variant, intron_variant | |
| rs1053356 | not-provided, Weak RhD expression | 25,301,552(-) | T/G | genic_downstream_transcript_variant, genic_upstream_transcript_variant, intron_variant | |
| rs1053359 | not-provided, Weak RhD expression | 25,301,582(-) | G/A/C | genic_downstream_transcript_variant, genic_upstream_transcript_variant, intron_variant | |
| rs1053362 | not-provided, Weak RhD expression | 25,301,629(-) | C/T | genic_downstream_transcript_variant, genic_upstream_transcript_variant, intron_variant | |
| rs121912762 | pathogenic, RhD category D-VII | 25,284,753(-) | T/C | genic_downstream_transcript_variant, genic_upstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv132n100 | CNV | gain | 25217958 |
| dgv133n100 | CNV | gain | 25217958 |
| dgv134n100 | CNV | gain | 25217958 |
| dgv135n100 | CNV | gain | 25217958 |
| esv3576582 | CNV | gain | 25503493 |
| nsv1160388 | CNV | duplication | 26073780 |
| nsv232 | CNV | deletion | 15895083 |
| nsv545825 | CNV | loss | 21841781 |
| nsv7298 | CNV | deletion | 18451855 |
Residual Variation Intolerance Score:
65% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.06;
68.81% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RSRP1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RSRP1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RSRP1 Gene
Disorders for RSRP1 Gene
Additional Disease Information for RSRP1
No disorders were found for RSRP1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RSRP1 Gene
Publications for RSRP1 Gene
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
- Elevated C1orf63 expression is correlated with CDK10 and predicts better outcome for advanced breast cancers: a retrospective study. (PMID: 26209438) Hong CQ … Cui YK (BMC cancer 2015) 3 58
Products for RSRP1 Gene
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
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- OriGene qPCR primer pairs and template standards for RSRP1
- OriGene qPCR primer pairs for RSRP1
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- GenScript: Design CRISPR guide RNA sequences for RSRP1
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- CloneReady with Over 120,000 Genes
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- Cloud-Clone Corp. disease models service
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- Invitrogen Antibodies for RSRP1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for RSRP1
- VectorBuilder custom plasmid, inducible vectors for RSRP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RSRP1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- GeneTex RSRP1 antibody for RSRP1
- Search GeneTex for Proteins for RSRP1
- ViGene Biosciences adenoviral particle packaged cDNA for RSRP1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for RSRP1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for RSRP1 gene
- Search ViGene Biosciences for RSRP1
- Horizon Cell Lines for RSRP1
- genomics-online: cdna clones - Search results for 38 available C1orf63 gene related products
- Overview of 38 available C1orf63 gene related products
- orf clones - Search results for 38 available C1orf63 gene related products
- Overview of 38 available C1orf63 gene related products
- genomics-online: gRNA clones - Search results for 38 available C1orf63 gene related products
- Overview of 38 available C1orf63 gene related products
- genomics-online: primer clones - Search results for 38 available C1orf63 gene related products
- Overview of 38 available C1orf63 gene related products
- genomics-online: shRNA clones - Search results for 38 available C1orf63 gene related products
- Overview of 38 available C1orf63 gene related products
Sources for RSRP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew