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Aliases for RSRC2 Gene

Aliases for RSRC2 Gene

  • Arginine/Serine-Rich Coiled-Coil 2 2 3

External Ids for RSRC2 Gene

Summaries for RSRC2 Gene

GeneCards Summary for RSRC2 Gene

RSRC2 (Arginine/Serine-Rich Coiled-Coil 2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RSRC2 Gene

Genomics for RSRC2 Gene

Genomic Location for RSRC2 Gene

Start:
122,503,458 bp from pter
End:
122,527,013 bp from pter
Size:
23,556 bases
Orientation:
Minus strand

Genomic View for RSRC2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RSRC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RSRC2 Gene

Regulatory Elements for RSRC2 Gene

Proteins for RSRC2 Gene

  • Protein details for RSRC2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7L4I2-RSRC2_HUMAN
    Recommended name:
    Arginine/serine-rich coiled-coil protein 2
    Protein Accession:
    Q7L4I2
    Secondary Accessions:
    • Q6N040
    • Q6NW16
    • Q9H864

    Protein attributes for RSRC2 Gene

    Size:
    434 amino acids
    Molecular mass:
    50560 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14755.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=EAW98327.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for RSRC2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RSRC2 Gene

Proteomics data for RSRC2 Gene at MOPED

Post-translational modifications for RSRC2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for RSRC2 Gene

Domains for RSRC2 Gene

Protein Domains for RSRC2 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

RSRC2_HUMAN
Family:
  • Belongs to the RSRC2 family.:
    • Q7L4I2
genes like me logo Genes that share domains with RSRC2: view

No data available for Gene Families for RSRC2 Gene

Function for RSRC2 Gene

Gene Ontology (GO) - Molecular Function for RSRC2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0044822 poly(A) RNA binding IDA 22681889
genes like me logo Genes that share ontologies with RSRC2: view

Phenotypes for RSRC2 Gene

GenomeRNAi human phenotypes for RSRC2:
genes like me logo Genes that share phenotypes with RSRC2: view

miRNA for RSRC2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RSRC2 Gene

Localization for RSRC2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RSRC2 Gene COMPARTMENTS Subcellular localization image for RSRC2 gene
Compartment Confidence
nucleus 3
cytosol 2
cytoskeleton 1

No data available for Gene Ontology (GO) - Cellular Components for RSRC2 Gene

Pathways for RSRC2 Gene

SuperPathways for RSRC2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RSRC2 Gene

None

No data available for Pathways by source for RSRC2 Gene

Transcripts for RSRC2 Gene

Unigene Clusters for RSRC2 Gene

Arginine/serine-rich coiled-coil 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RSRC2 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11a ·
SP1: - - - - - - - - -
SP2: - - - - - - - -
SP3: - - - - - - - - - - -
SP4: - - - - - - - - - -
SP5: - - - - - - -
SP6: - - - - - - - - - -
SP7: - - - - - -
SP8: - - - -
SP9: - - - - - - - - - - - - - -
SP10: - - - - - - -
SP11: - - - - - - - - - - - - -
SP12: - - - - - - - - - -
SP13: - - - -
SP14: - - - - - -

ExUns: 11b ^ 12 ^ 13 ^ 14a · 14b · 14c
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:

Relevant External Links for RSRC2 Gene

GeneLoc Exon Structure for
RSRC2
ECgene alternative splicing isoforms for
RSRC2

Expression for RSRC2 Gene

mRNA expression in normal human tissues for RSRC2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RSRC2 Gene

SOURCE GeneReport for Unigene cluster for RSRC2 Gene Hs.432996

genes like me logo Genes that share expressions with RSRC2: view

Orthologs for RSRC2 Gene

This gene was present in the common ancestor of animals.

Orthologs for RSRC2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RSRC2 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RSRC2 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RSRC2 37
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rsrc2 16
Rsrc2 37
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RSRC2 37
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RSRC2 37
  • 96 (a)
OneToOne
chicken
(Gallus gallus)
Aves RSRC2 37
  • 89 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RSRC2 37
  • 91 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia flj11021-prov 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.10041 36
zebrafish
(Danio rerio)
Actinopterygii rsrc2 37
  • 69 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG6340 37
  • 23 (a)
OneToOne
Species with no ortholog for RSRC2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RSRC2 Gene

ENSEMBL:
Gene Tree for RSRC2 (if available)
TreeFam:
Gene Tree for RSRC2 (if available)

Paralogs for RSRC2 Gene

Selected SIMAP similar genes for RSRC2 Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for RSRC2 Gene

genes like me logo Genes that share paralogs with RSRC2: view

No data available for Paralogs for RSRC2 Gene

Variants for RSRC2 Gene

Sequence variations from dbSNP and Humsavar for RSRC2 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs10998 -- 122,504,865(-) ACTTA(C/T)TAAAA utr-variant-3-prime, nc-transcript-variant
rs14519 -- 122,505,264(+) CAGCT(C/T)TTATA utr-variant-3-prime, nc-transcript-variant
rs1115154 -- 122,505,495(+) AGTCT(A/G)TAAGT utr-variant-3-prime, nc-transcript-variant
rs1499681 -- 122,504,232(-) TGGCT(C/T)TCCTT downstream-variant-500B
rs1532578 -- 122,511,674(-) GGTTT(C/G)CTTGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RSRC2 Gene

Variant ID Type Subtype PubMed ID
nsv899570 CNV Gain 21882294
esv2574323 CNV Deletion 19546169
esv2279643 CNV Deletion 18987734
esv1004502 CNV Deletion 20482838
esv5088 CNV Deletion 18987735
esv2746498 CNV Deletion 23290073
esv993685 CNV Deletion 20482838
esv2501949 CNV Deletion 19546169
esv9727 CNV Loss 19470904
esv1035767 CNV Deletion 17803354
nsv53703 CNV Loss 16902084

Relevant External Links for RSRC2 Gene

HapMap Linkage Disequilibrium report
RSRC2

Disorders for RSRC2 Gene

No disorders were found for RSRC2 Gene.

No data available for UniProtKB/Swiss-Prot for RSRC2 Gene

Publications for RSRC2 Gene

  1. A novel gene, RSRC2, inhibits cell proliferation and affects survival in esophageal cancer patients. (PMID: 17203224) Kurehara H. … Kuwabara Y. (Int. J. Oncol. 2007) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. A protein interaction framework for human mRNA degradation. (PMID: 15231747) Lehner B. … Sanderson C.M. (Genome Res. 2004) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PMID: 16713569) Lim J. … Zoghbi H.Y. (Cell 2006) 3

Products for RSRC2 Gene

Sources for RSRC2 Gene

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