Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RSPH10B2 Gene

Aliases for RSPH10B2 Gene

  • Radial Spoke Head 10 Homolog B2 2 3 5
  • Radial Spoke Head 10 Homolog B2 (Chlamydomonas) 2

External Ids for RSPH10B2 Gene

Previous GeneCards Identifiers for RSPH10B2 Gene

  • GC07P006761

Summaries for RSPH10B2 Gene

GeneCards Summary for RSPH10B2 Gene

RSPH10B2 (Radial Spoke Head 10 Homolog B2) is a Protein Coding gene. An important paralog of this gene is RSPH10B.

Gene Wiki entry for RSPH10B2 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RSPH10B2 Gene

Genomics for RSPH10B2 Gene

Regulatory Elements for RSPH10B2 Gene

Enhancers for RSPH10B2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F006792 1 Ensembl ENCODE 0.3 +38.6 38551 0.9 SAP130 MLX FOXA3 ARID4B MXD4 MNT RARA FOXK2 SMAD4 BCL6 PIR61703 RSPH10B2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around RSPH10B2 on UCSC Golden Path with GeneCards custom track

Promoters for RSPH10B2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001888932 92 401

Genomic Location for RSPH10B2 Gene

6,754,108 bp from pter
6,799,365 bp from pter
45,258 bases
Plus strand

Genomic View for RSPH10B2 Gene

Genes around RSPH10B2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RSPH10B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RSPH10B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RSPH10B2 Gene

Proteins for RSPH10B2 Gene

  • Protein details for RSPH10B2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Radial spoke head 10 homolog B2
    Protein Accession:
    Secondary Accessions:
    • A6NMW7
    • B2RXI4
    • B2RXJ0
    • Q86ST9
    • Q8NE68

    Protein attributes for RSPH10B2 Gene

    870 amino acids
    Molecular mass:
    100547 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAG37482.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for RSPH10B2 Gene


neXtProt entry for RSPH10B2 Gene

Post-translational modifications for RSPH10B2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for RSPH10B2 Gene

Domains & Families for RSPH10B2 Gene

Protein Domains for RSPH10B2 Gene


Suggested Antigen Peptide Sequences for RSPH10B2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 10 MORN repeats.
  • Contains 10 MORN repeats.
genes like me logo Genes that share domains with RSPH10B2: view

No data available for Gene Families for RSPH10B2 Gene

Function for RSPH10B2 Gene

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RSPH10B2 Gene

Localization for RSPH10B2 Gene

Subcellular locations from

Jensen Localization Image for RSPH10B2 Gene COMPARTMENTS Subcellular localization image for RSPH10B2 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RSPH10B2 Gene

Pathways & Interactions for RSPH10B2 Gene

SuperPathways for RSPH10B2 Gene

No Data Available

Interacting Proteins for RSPH10B2 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000297186 B2RC85-R10B2_HUMAN for RSPH10B2 Gene via STRING IID

Gene Ontology (GO) - Biological Process for RSPH10B2 Gene


No data available for Pathways by source and SIGNOR curated interactions for RSPH10B2 Gene

Transcripts for RSPH10B2 Gene

mRNA/cDNA for RSPH10B2 Gene

(6) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(11) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RSPH10B2 Gene

Radial spoke head 10 homolog B2 (Chlamydomonas):
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RSPH10B2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c · 10d ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14
SP1: -
SP2: - -
SP3: -
SP5: -

Relevant External Links for RSPH10B2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RSPH10B2 Gene

mRNA expression in normal human tissues for RSPH10B2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RSPH10B2 Gene

This gene is overexpressed in Testis (x26.2).

NURSA nuclear receptor signaling pathways regulating expression of RSPH10B2 Gene:


SOURCE GeneReport for Unigene cluster for RSPH10B2 Gene:

genes like me logo Genes that share expression patterns with RSPH10B2: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RSPH10B2 Gene

Orthologs for RSPH10B2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RSPH10B2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC738574 34
  • 98.68 (n)
-- 35
  • 98 (a)
(Canis familiaris)
Mammalia RSPH10B 34
  • 81.36 (n)
-- 35
  • 76 (a)
(Bos Taurus)
Mammalia RSPH10B 34
  • 79.52 (n)
-- 35
  • 74 (a)
(Rattus norvegicus)
Mammalia Rsph10b 34
  • 76.84 (n)
(Mus musculus)
Mammalia Rsph10b 34 16 35
  • 76.42 (n)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 67 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 63 (a)
(Gallus gallus)
Aves RSPH10B 34
  • 60.76 (n)
-- 35
  • 46 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 59 (a)
-- 35
  • 49 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rsph10b 34
  • 59.47 (n)
(Danio rerio)
Actinopterygii zgc:153062 34
  • 56.75 (n)
RSPH10B 35
  • 42 (a)
Species where no ortholog for RSPH10B2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RSPH10B2 Gene

Gene Tree for RSPH10B2 (if available)
Gene Tree for RSPH10B2 (if available)

Paralogs for RSPH10B2 Gene

Paralogs for RSPH10B2 Gene

(5) SIMAP similar genes for RSPH10B2 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with RSPH10B2: view

Variants for RSPH10B2 Gene

Sequence variations from dbSNP and Humsavar for RSPH10B2 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10225697 -- 6,794,117(+) CATGC(A/T)CACCT intron-variant
rs10234394 -- 6,781,401(+) TATCT(C/T)GCTTA reference, synonymous-codon
rs10265755 -- 6,793,885(+) ACTTT(C/T)CCCTC intron-variant
rs10266030 -- 6,794,093(+) CTAGG(C/T)ATCTT intron-variant
rs10266262 -- 6,794,241(+) TTTTG(C/T)TCCAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RSPH10B2 Gene

Variant ID Type Subtype PubMed ID
dgv1864e212 CNV loss 25503493
dgv1865e212 CNV loss 25503493
dgv1866e212 CNV loss 25503493
dgv1867e212 CNV loss 25503493
dgv6241n100 CNV gain 25217958
dgv6243n100 CNV loss 25217958
esv2752174 CNV gain 17911159
esv2759504 CNV loss 17122850
esv2762647 CNV gain 21179565
esv33385 CNV gain 17666407
esv3571591 CNV loss 25503493
esv3571605 CNV loss 25503493
nsv1017061 CNV loss 25217958
nsv1034916 CNV gain 25217958
nsv1074069 CNV deletion 25765185
nsv1077484 CNV duplication 25765185
nsv1141527 CNV duplication 24896259
nsv1147398 CNV duplication 26484159
nsv1153955 CNV duplication 26484159
nsv436904 CNV insertion 17901297
nsv7392 OTHER inversion 18451855
nsv8037 CNV gain 18304495
nsv8040 CNV gain 18304495
nsv830892 CNV loss 17160897
nsv830894 CNV loss 17160897
nsv966754 CNV duplication 23825009
nsv970789 CNV duplication 23825009

Variation tolerance for RSPH10B2 Gene

Gene Damage Index Score: 6.01; 74.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RSPH10B2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RSPH10B2 Gene

Disorders for RSPH10B2 Gene

Relevant External Links for RSPH10B2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RSPH10B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RSPH10B2 Gene

Publications for RSPH10B2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4 64

Products for RSPH10B2 Gene

Sources for RSPH10B2 Gene

Loading form....