RSPH10B Gene
protein-coding GIFtS: 39
GCID: GC07M005935
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radial spoke head 10 homolog B (Chlamydomonas)
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Aliases
for RSPH10B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Radial Spoke Head 10 Homolog B (Chlamydomonas)1 2 | | Radial Spoke Head 10 Homolog B2 | | Radial Spoke Head 10 Homolog B22 |
Export aliases for RSPH10B gene to outside databases |
Summaries
for RSPH10B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for RSPH10B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RSPH10B gene promoter:
GR Max1 AP-1 GR-beta E4BP4 E47 COMP1 GR-alpha c-Myc Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for RSPH10B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RSPH10B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p22.1 Ensembl cytogenetic band: 7p22.1 HGNC cytogenetic band: 7p22.2RSPH10B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M005935: view genomic region
(about GC identifiers)
Start:
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5,965,177 bp from pter |
End:
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6,010,314 bp from pter |
Size:
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45,138 bases |
Orientation:
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minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 6,012,122-6,056,659 |
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Proteins
for RSPH10B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: R10B1_HUMAN, P0C881 (See
protein sequence)Recommended Name: Radial spoke head 10 homolog B Size: 870 amino acids; 100635 Da
Secondary accessions: A6NMW7 Q86ST9 Q8NE68Explore the universe of human proteins at neXtProt for RSPH10B: NX_P0C881
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P0C881
RSPH10B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_775836.3
ENSEMBL proteins: ENSP00000440914 ENSP00000385443 ENSP00000384097 ENSP00000444512 ENSP00000390326 ENSP00000338556 ENSP00000400988 ENSP00000445203
Human Recombinant Protein Products for RSPH10B:
RSPH10B Antibody Products:
Assay Products for RSPH10B: |
Protein
Domains /
Families
for RSPH10B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RSPH10B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P0C881ProtoNet protein and cluster: P0C881 UniProtKB/Swiss-Prot: R10B1_HUMAN, P0C881Similarity: Contains 10 MORN repeats |
Function
for RSPH10B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RSPH10B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RSPH10B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RSPH10B (NM_173565) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RSPH10B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RSPH10B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RSPH10B |
|
Pathways & Interactions
for RSPH10B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RSPH10B
|
Drugs & Compounds
for RSPH10B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RSPH10B
Search CenterWatch for drugs/clinical trials and news about RSPH10B / R10B1
|
Transcripts
for RSPH10B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RSPH10B gene: NM_173565.3 Unigene Cluster for RSPH10B: Radial spoke head 10 homolog B (Chlamydomonas) Hs.442339 [show with all ESTs]Unigene Representative Sequence: BC03449512 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000538522(uc021zze.1) ENST00000405415(uc010ktd.1) ENST00000404406(uc003sph.1)
ENST00000535104(uc011jwk.2) ENST00000541997 ENST00000477641 ENST00000539630
ENST00000542644 ENST00000455618 ENST00000337579(uc003spg.1) ENST00000441023
ENST00000539903
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RSPH10B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RSPH10B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RSPH10B (NM_173565) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RSPH10B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RSPH10B |
Additional cDNA sequence: BC034495.1 BC157864.1 BC157871.1 7 DOTS entries: DT.95258690 DT.121095965 DT.95255883 DT.121096044 DT.97809241 DT.121128032 DT.121128023 16 AceView cDNA sequences: BG722304 AA382672 CB241675 AX748110 NM_173565 AK093411 AW474289 AA844689 BC034495 BI460936 BG717722 AA383246 AW872691 AA868223 AA021610 AA021177
GeneLoc Exon Structure
|
Expression
for RSPH10B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RSPH10B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTGGATTAC
About this image
See RSPH10B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RSPH10B
SOURCE GeneReport for Unigene cluster: Hs.442339
SABiosciences Custom PCR Arrays for RSPH10B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RSPH10B
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat RSPH10B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RSPH10B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RSPH10B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RSPH10B |
Orthologs
for RSPH10B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for RSPH10B gene from 4/17 species (see all 17) About this table
ENSEMBL Gene Tree for RSPH10B (if available)
TreeFam Gene Tree for RSPH10B (if available) |
Paralogs
for RSPH10B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RSPH10B gene
- RSPH10B21 2 JPH22 JPH42 MORN42 JPH12 ALS2CL2 JPH32 MORN12
- RSPH12 ALS22 MORN32
5 SIMAP similar genes for RSPH10B using alignment to 3 protein entries: R10B1_HUMAN (see all proteins):RSPH10B2 MORN2 MORN4 LOC118812 MORN1
RSPH10B for paralogs About GeneDecksing
|
Genomic Variants
for RSPH10B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RSPH10B (5965177 - 6010314 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for RSPH10B
5 CNVs: 2673 8546 31331 81858 7643
1 Inversion: 37290 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RSPH10B |
|
Disorders
/ Diseases
for RSPH10B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RSPH10B for disorders About GeneDecksing
2  diseases for RSPH10B: About MalaCardspneumonia malaria
Export disorders for RSPH10B gene to outside databases
|
Publications
for RSPH10B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RSPH10B gene integrated from 9 sources:
(articles sorted by number of sources associating them with RSPH10B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Radial spoke proteins of Chlamydomonas flagella. (PubMed id 16507594)1, 3 Yang P....Witman G.B. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for RSPH10B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RSPH10B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RSPH10B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RSPH10B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RSPH10B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RSPH10B gene:
Search GeneIP for patents involving RSPH10B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RSPH10B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RSPH10B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RSPH10B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RSPH10B | | | OriGene Protein Over-expression Lysate for RSPH10B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RSPH10B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RSPH10B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RSPH10B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RSPH10B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RSPH10B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RSPH10B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RSPH10B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RSPH10B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RSPH10B |
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 |  |  |  | |
| | | | Search Tocris compounds for RSPH10B |
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 | | | RSPH10B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RSPH10B |
|  |  |  |  | | | | Search ThermoFisher Antibodies for RSPH10B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RSPH10B |
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