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CLIP1 Gene

protein-coding GIFtS: 53

GC12M121322

CAP-GLY domain containing linker protein 1
(Previous name: restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: RSN)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CLIP ^¹, ²
CLIP-170 ^¹, ², ³
CLIP170 ^¹, ²
CYLN1 ^¹, ², ³
MGC131604 ^²
RSN ^², ³
Restin ^³
restin ^²

Descriptions
CAP-GLY domain containing linker protein 1 ^²
Cytoplasmic linker protein 1 ^³
Cytoplasmic linker protein 170 alpha-2 ^³
Reed-Steinberg cell-expressed intermediate filament-associated protein ^²
Reed-Sternberg intermediate filament-associated protein ^³
cytoplasmic linker 1 ^²
restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) ^¹, ²

External Ids
HGNC: 10461¹
Entrez Gene: 6249²
UniProtKB: P30622³
Ensembl: ENSG00000130779⁷

Search outside databases for aliases for CLIP1 gene

Previous GC identifer: GC12M121205

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CLIP1_HUMAN, P30622

Function: Seems to be a intermediate filament associated protein that links endocytic vesicles to

microtubules

Gene Wiki entry for CLIP1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.3 Ensembl cytogenetic band: 12q24.31 HGNC cytogenetic band: 12q24.3

CLIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M121322: (about GC identifiers)

Start:	121,321,934 bp from pter
End:	121,473,069 bp from pter
Size:	151,136 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000012.10 NT_009755.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: CLIP1_HUMAN, P30622 (See protein sequence)

Recommended Name: CAP-Gly domain-containing linker protein 1

Size: 1427 amino acids; 160990 Da

Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with the cytoskeleton

PDB structures from and Proteopedia :

2CP5 (3D)

2CP6 (3D)

2E3H (3D)

2E3I (3D)

2E4H (3D)

2HQH (3D)

2QK0 (3D)

3E2U (3D)

Alternative splicing: 2 isoforms: P30622-1 P30622-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_002947.1 NP_937883.1

ENSEMBL proteins:

ENSP00000303585 ENSP00000351665 ENSP00000355314 ENSP00000376252

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (CLIP170)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000776	kinetochore	TAS	15928712
GO:0005737	cytoplasm	IEA	--
GO:0005768	endosome	TAS	1356075
GO:0005874	microtubule	IEA	--
GO:0005882	intermediate filament	TAS	1600942

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Antibodies for CLIP1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for CLIP1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (CLIP170), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for CLIP1

Assays for CLIP1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P30622

ProtoNet protein and cluster: P30622

2 Blocks protein families:

IPB000938 CAP-Gly domain

IPB001878 C2HC-type zinc-finger signature

UniProtKB/Swiss-Prot: CLIP1_HUMAN, P30622

Similarity: Contains 2 CAP-Gly domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CLIP1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (RSN)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_198240

Applied Biosystems Silencer® siRNAs for CLIP1

Sigma-Aldrich siRNA for CLIP1

Sigma-Aldrich shRNA Panels and shRNA for CLIP1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_002956
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_002956
untagged cDNA clones in CMV expression vector (see all 2): NM_002956

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002956

UniProtKB/Swiss-Prot: CLIP1_HUMAN, P30622

Function: Seems to be a intermediate filament associated protein that links endocytic vesicles to

microtubules

2 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Clip1):

cellular

reproductive system

5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003676	nucleic acid binding	IEA	--
GO:0005515	protein binding	IPI	11940666
GO:0008017	microtubule binding	TAS	10052454
GO:0008270	zinc ion binding	IEA	--
GO:0042803	protein homodimerization activity	TAS	15928712

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for CLIP1

5/108 Interacting proteins for CLIP1 (ENSP00000351665³ P30622²) via UniProtKB, MINT, and/or STRING (see all 108 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TUBA4A	P68366²	STRING (score=.863) MINT-1789920 MINT-1781370 MINT-1781342
DCTN1	Q14203²	STRING (score=.993) MINT-2738062
MAPRE1	Q15691²	STRING (score=.997) MINT-1781393
CLASP2	ENSP00000327760³	STRING (score=.997)
IQGAP1	ENSP00000268182³	STRING (score=.996)

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1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007067	mitosis	TAS	15928712

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CLIP1
5 Novoseek chemical compound relationships for CLIP1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
gtp	24.33	2	16120651 (1)
ionomycin	17.62	1	10620705 (1)
hydrogen	0.00	1	7667280 (1)
calcium	0.00	2	16369480 (2)
zinc	0.00	6	17563362 (2), 11940666 (2), 17828277 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CLIP1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (RSN)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_198240

Sigma-Aldrich siRNA for CLIP1

Sigma-Aldrich shRNA Panels and shRNA for CLIP1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002956 NM_198240

REFSEQ mRNAs for CLIP1 gene (2 alternative transcripts):

NM_002956.2 NM_198240.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002956 NM_198240

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_002956
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_002956
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_002956

Additional cDNA sequence:

AB209115.1 AF045652.1 AF045653.1 AK126990.1 AY563000.1 BC047895.1 BC062543.1 BC114213.1

BC117209.1 BC126305.1 M97501.1 X64838.1

21 DOTS entries:

DT.217772 DT.101983195 DT.99941429 DT.95371234 DT.97822056 DT.95371227 DT.92068744 DT.95305617

DT.121159268 DT.121159305 DT.304362 DT.97845116 DT.100788755 DT.91721355 DT.91749921 DT.91885310

DT.100788754 DT.86841094 DT.95156652 DT.92012465 DT.99975989

24/283 AceView cDNA sequences (see all 283 ):

BU192156 BM856968 BU788009 BX646973 AI913555 NM_002956 CA395393 BQ278921

AA307304 BF431741 AL596826 BX477400 NM_198240 AA069706 AW950144 CA314875

H12584 BP364071 AA313570 AL713517 BC047895 AI583719 BU784341 BE349309

highest scoring ESTs for CLIP1:

X64838 AL603324 AL713517 AW008377 AW270831 AW294721 AW451194 BF849789 M97501 AA069706

Unigene Cluster for CLIP1:

CAP-GLY domain containing linker protein 1

Hs.524809 [show with all ESTs]

Unigene Representative Sequence: NM_002956

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for CLIP1 (see all 9 )

ExUns:	1	^	2	^	3	^	4	^	5a	·	5b	^	6a	·	6b	^	7	^	8	^	9	^	10	^	11a	·	11b	·	11c	^	12	^	13	^	14	^	15a	·	15b	^	16a	·	16b	^	17a	·	17b	^	18	^	19	^
SP1:											-				-						-																										-
SP2:											-				-						-		-																								-
SP3:											-		-		-
SP4:
SP5:

ExUns:	20	^	21	^	22a	·	22b	^	23	^	24a	·	24b	^	25	^	26a	·	26b	^	27a	·	27b	·	27c	·	27d
SP1:					-								-		-
SP2:					-								-		-
SP3:
SP4:													-		-		-
SP5:

About this scheme

ECgene alternative splicing isoforms for CLIP1

4 Ensembl transcripts including schematic representations:

ENST00000302528 ENST00000358808 ENST00000361654 ENST00000392458

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CLIP1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CLIP1

¹ / ² / ³

11 probe-sets matching CLIP1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
75192_at²^{, 3}	U95-D	1	1.00	1.00	0.78	1.41	AW008377	0.80	1.00	0.91	1
34350_at²^{, 3}	U95-A	1	1.00	1.00	0.93	1.07	X64838	1.00	1.00	1.00	1
84437_r_at²^{, 3}	U95-E	1	1.00	1.00	0.56	0.49	AA976356	0.60	1.00	0.82	1
76751_at²^{, 3}	U95-D	1	0.50	1.00	0.79	1.06	AA868722	0.60	1.00	0.82	1
210716_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	M97501	0.80	1.00	0.91	1
201975_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002956	0.60	1.00	0.82	1
242287_at²^{, 3}	U133-B	1	0.73	1.00	--	--	AI090487	0.20	1.00	0.72	1
210716_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1558924_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
201975_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
242287_at²	U133Plus2	1	0.73	1.00	--	--	--	--	--	--	--

GeneDecks CLIP1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TAAAGCAGTA

SOURCE GeneReport for Unigene cluster: Hs.524809
UniProtKB/Swiss-Prot: CLIP1_HUMAN, P30622
Tissue specificity: Highly expressed in the Reed-Sternberg cells of Hodgkin's disease

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for CLIP1 gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	CLIP1¹	--	CAP-GLY domain containing linker protein 1	89.96(n) 91.66(a)	477461 XM_854226.1 XP_859319.1
chimpanzee (Pan troglodytes)	CLIP1¹	--	CAP-GLY domain containing linker protein 1	99.53(n) 99.51(a)	467147 XM_001167353.1 XP_001167353.1
cow (Bos taurus)	CLIP1¹	--	CAP-GLY domain containing linker protein 1	89.65(n) 92.15(a)	534624 XM_614458.3 XP_614458.2
mouse (Mus musculus)	Clip1^{1, 5}	5⁵	CAP-GLY domain containing linker protein 1^{1, 5}	87.11(n)¹ 89.79(a)¹	56430¹ NM_019765.3¹ NP_062739.2¹ AA667101⁵ AF185286⁵ (see all 20)
chicken (Gallus gallus)	CLIP1¹	--	CAP-GLY domain containing linker protein 1	75.74(n) 74.68(a)	395784 NM_204942.1 NP_990273.1

About this table Species with no ortholog for CLIP1

ENSEMBL Gene Tree for CLIP1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for CLIP1 gene

CLIP2² TBCB²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/899 NCBI SNPs in CLIP1 are shown (see all 899 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 129)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs10270^1,2	A,C,F,H	121322295(-)	`TAATTT/CTGGAT`	2	--	ut3¹ ese³		9		MN NA EU EA WA	928
	rs1129167^1,2	A,C,F,H	121378456(-)	`GCCGAC/GAAAGC`	2	D/E	mis¹		19		EA NA NS EU WA	3379
--	rs7388^1,2	C,F,H,O	121322137(-)	`ACTTCT/AATAAT`	2	--	ut3¹ ese³		9		MN NA EU EA WA	926
	rs1803290^1,2	C,F,H	121430982(-)	`AGGCAA/GAGGAG`	2	--	ut5¹ ese³ trp³		6		NA EA WA	426
	rs3741447^1,2	C,F,H	121391366(+)	`TTTCCG/AAAGTG`	2	W/R	mis¹		9		EA EU WA	2328
	rs7963597^1,2	A,H	121428062(+)	`GGTGGA/GGGGGG`	2	S/P	mis¹ trp³		4		EU EA WA	414
	rs11057808^1,2	C,H	121428412(+)	`ATGGAG/CTGCTT`	2	S/T	mis¹		4		EU EA WA	418
--	rs7964911^1,2	A,C	121321497(+)	`ttgggC/Tggccg`	2	--	ng5¹		0	--	--	--	--
	rs17883517^1,2	C,F	121383533(+)	`AGAAGA/GGTTAT`	2	S/P	mis¹		6		NS NA EU EA WA	899
	rs1046800^1,2	C	121322636(-)	`TTTGGA/GAAAAA`	2	--	ut3¹		0	--	--	--	--

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HapMap Linkage Disequilibrium images for CLIP1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 179838

5 Novoseek disease relationships for CLIP1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
hla-do	91.59	3	9382849 (2), 16191436 (1)
familial adenomatous polyposis	29.77	3	18560734 (1), 17085436 (1), 16355537 (1)
hodgkin disease	15.85	2	9746762 (1), 8222754 (1)
autoimmunity	0.00	2	9550430 (1), 11739539 (1)
autoimmune diseases	0.00	1	16181341 (1)

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/130 PubMed articles for CLIP1 gene (see all 130 ):

Localization of the gene (RSN) coding for restin, a marker for Reed-Sternberg cells in Hodgkin's disease, to human chromosome band 12q24.3 and YAC cloning of the locus. (PubMed id 8222754)^{1, 2, 3} Hilliker C....Van den Berghe H. (1994)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{3, 4} Beausoleil S.A.... Gygi S.P. (2006)
Phosphoproteome analysis of the human mitotic spindle. (PubMed id 16565220)^{3, 4} Nousiainen M.... Koerner R. (2006)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
Global phosphoproteome of HT-29 human colon adenocarcinoma cells. (PubMed id 16083285)^{3, 4} Kim J.-E.... White F.M. (2005)
Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)^{3, 4} Beausoleil S.A....Gygi S.P. (2004)
Restin: a novel intermediate filament-associated protein highly expressed in the Reed-Sternberg cells of Hodgkin's disease. (PubMed id 1600942)^{3, 4} Bilbe G.... Shipman R. (1992)
CLIP-170 links endocytic vesicles to microtubules. (PubMed id 1356075)^{3, 4} Pierre P.... Kreis T.E. (1992)
CLIP-170 facilitates the formation of kinetochore-microtubule attachments. (PubMed id 16362039)^{1, 3} Tanenbaum M.E....Medema R.H. (2006)
Interactions between CLIP-170, tubulin, and microtubules: implications for the mechanism of Clip-170 plus-end tracking behavior. (PubMed id 16120651)^{1, 3} Folker E.S....Goodson H.V. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 6249	HGNC: 10461	AceView: RSN	Ensembl:ENSG00000130779	euGenes: HUgn6249
ECgene: CLIP1	H-InvDB: CLIP1

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for CLIP1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for CLIP1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CLIP1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for CLIP1		Antibodies for CLIP1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for CLIP1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
CLIP1 Gene at Home site.
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CLIP1 Gene

protein-coding GIFtS: 53

Aliases &
Descriptions
for CLIP1

Summaries
for CLIP1

Genomic Location
for CLIP1

Proteins
for CLIP1

Protein Domains/
Families
for CLIP1

Gene Function
for CLIP1

Pathways & Interactions
for CLIP1

Drugs & Compounds
for CLIP1

Transcripts
for CLIP1

Expression
for CLIP1

Orthologs
for CLIP1

Paralogs
for CLIP1

SNPs/Variants
for CLIP1

Disorders & Mutations
for CLIP1

Medical News
for CLIP1

Publications
for CLIP1

Search for CLIP1

Genome Databases showing CLIP1

Other Databases showing CLIP1

Specialized Databases showing CLIP1

Licensable Technologies
for CLIP1

Services
for CLIP1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CLIP1 Gene

protein-coding GIFtS: 53

Aliases & Descriptionsfor CLIP1

Summariesfor CLIP1

Genomic Locationfor CLIP1

Proteinsfor CLIP1

Protein Domains/Familiesfor CLIP1

Gene Functionfor CLIP1

Pathways & Interactionsfor CLIP1

Drugs & Compoundsfor CLIP1

Transcriptsfor CLIP1

Expression for CLIP1

Orthologsfor CLIP1

Paralogsfor CLIP1

SNPs/Variantsfor CLIP1

Disorders & Mutationsfor CLIP1

Medical Newsfor CLIP1

Publicationsfor CLIP1

Search for CLIP1

Genome Databases showing CLIP1

Other Databases showing CLIP1

Specialized Databases showing CLIP1

Licensable Technologiesfor CLIP1

Servicesfor CLIP1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CLIP1

Summaries
for CLIP1

Genomic Location
for CLIP1

Proteins
for CLIP1

Protein Domains/
Families
for CLIP1

Gene Function
for CLIP1

Pathways & Interactions
for CLIP1

Drugs & Compounds
for CLIP1

Transcripts
for CLIP1

Expression
for CLIP1

Orthologs
for CLIP1

Paralogs
for CLIP1

SNPs/Variants
for CLIP1

Disorders & Mutations
for CLIP1

Medical News
for CLIP1

Publications
for CLIP1

Licensable Technologies
for CLIP1

Services
for CLIP1