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Aliases for RSL24D1 Gene

Aliases for RSL24D1 Gene

  • Ribosomal L24 Domain Containing 1 2 3
  • Ribosomal L24 Domain-Containing Protein 1 3 4
  • C15orf15 3 4
  • RPL24L 3 4
  • RLP24 3 6
  • Homolog Of Yeast Ribosomal Like Protein 24 3
  • Probable Ribosome Biogenesis Protein RLP24 3
  • Chromosome 15 Open Reading Frame 15 2
  • 60S Ribosomal Protein L30 Isolog 3
  • Ribosomal Protein L24-Like 4
  • My024 Protein 3
  • HRP-L30-Iso 3
  • RPL24 3
  • TVAS3 3
  • L30 3

External Ids for RSL24D1 Gene

Previous HGNC Symbols for RSL24D1 Gene

  • C15orf15

Previous GeneCards Identifiers for RSL24D1 Gene

  • GC15M053261
  • GC15M055473
  • GC15M032299

Summaries for RSL24D1 Gene

Entrez Gene Summary for RSL24D1 Gene

  • This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The protein encoded by this gene localizes to the nucleolus and is thought to play a role in the biogenesis of the 60S ribosomal subunit. The precise function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals and has multiple pseudogenes. [provided by RefSeq, Jul 2012]

GeneCards Summary for RSL24D1 Gene

RSL24D1 (Ribosomal L24 Domain Containing 1) is a Protein Coding gene. Among its related pathways are Disease and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein.

UniProtKB/Swiss-Prot for RSL24D1 Gene

  • Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity).

Gene Wiki entry for RSL24D1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RSL24D1 Gene

Genomics for RSL24D1 Gene

Regulatory Elements for RSL24D1 Gene

Genomic Location for RSL24D1 Gene

55,180,806 bp from pter
55,197,067 bp from pter
16,262 bases
Minus strand

Genomic View for RSL24D1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RSL24D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RSL24D1 Gene

Proteins for RSL24D1 Gene

  • Protein details for RSL24D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Probable ribosome biogenesis protein RLP24
    Protein Accession:
    Secondary Accessions:
    • B2RD72
    • Q561V8
    • Q8N6S8
    • Q96B04
    • Q96C76
    • Q96HJ1

    Protein attributes for RSL24D1 Gene

    163 amino acids
    Molecular mass:
    19621 Da
    Quaternary structure:
    • Associated with nucleolar and cytoplasmic pre-60S particles. At the end of biogenesis it dissociates from cytoplasmic pre-60S particles and is likely to be exchanged for its ribosomal homolog, RPL24 (By similarity).

neXtProt entry for RSL24D1 Gene

Proteomics data for RSL24D1 Gene at MOPED

Post-translational modifications for RSL24D1 Gene

  • Ubiquitination at Lys27, Lys73, and Lys88
  • Modification sites at PhosphoSitePlus

Other Protein References for RSL24D1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RSL24D1 Gene

Domains for RSL24D1 Gene

Suggested Antigen Peptide Sequences for RSL24D1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9UHA3
  • Belongs to the ribosomal protein L24e family.
genes like me logo Genes that share domains with RSL24D1: view

No data available for Gene Families for RSL24D1 Gene

Function for RSL24D1 Gene

Molecular function for RSL24D1 Gene

UniProtKB/Swiss-Prot Function: Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity).

Gene Ontology (GO) - Molecular Function for RSL24D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003735 structural constituent of ribosome IEA --
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with RSL24D1: view
genes like me logo Genes that share phenotypes with RSL24D1: view

miRNA for RSL24D1 Gene

miRTarBase miRNAs that target RSL24D1

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RSL24D1 Gene

Localization for RSL24D1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RSL24D1 Gene

Nucleus, nucleolus.

Subcellular locations from

Jensen Localization Image for RSL24D1 Gene COMPARTMENTS Subcellular localization image for RSL24D1 gene
Compartment Confidence
nucleus 5
cytosol 3
mitochondrion 2
extracellular 1

Gene Ontology (GO) - Cellular Components for RSL24D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
GO:0005840 ribosome IEA --
genes like me logo Genes that share ontologies with RSL24D1: view

Pathways for RSL24D1 Gene

genes like me logo Genes that share pathways with RSL24D1: view

Pathways by source for RSL24D1 Gene

1 KEGG pathway for RSL24D1 Gene
1 GeneGo (Thomson Reuters) pathway for RSL24D1 Gene

Gene Ontology (GO) - Biological Process for RSL24D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006412 translation IEA --
GO:0042254 ribosome biogenesis IEA --
genes like me logo Genes that share ontologies with RSL24D1: view

Compounds for RSL24D1 Gene

(3) Drugbank Compounds for RSL24D1 Gene

Compound Synonyms Cas Number Type Actions PubMed IDs
Alpha-Hydroxy-Beta-Phenyl-Propionic Acid
genes like me logo Genes that share compounds with RSL24D1: view

Transcripts for RSL24D1 Gene

Unigene Clusters for RSL24D1 Gene

Ribosomal L24 domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RSL24D1 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b
SP1: - -
SP2: -
SP3: -

Relevant External Links for RSL24D1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RSL24D1 Gene

mRNA expression in normal human tissues for RSL24D1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RSL24D1 Gene

SOURCE GeneReport for Unigene cluster for RSL24D1 Gene Hs.274772

genes like me logo Genes that share expressions with RSL24D1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RSL24D1 Gene

Orthologs for RSL24D1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RSL24D1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RSL24D1 35
  • 99.59 (n)
  • 100 (a)
RSL24D1 36
  • 100 (a)
(Bos Taurus)
Mammalia RSL24D1 35
  • 90.95 (n)
  • 96.91 (a)
RSL24D1 36
  • 96 (a)
(Canis familiaris)
Mammalia RSL24D1 35
  • 92.96 (n)
  • 98.76 (a)
RSL24D1 36
  • 98 (a)
(Mus musculus)
Mammalia Rsl24d1 35
  • 87.86 (n)
  • 98.77 (a)
Rsl24d1 16
Rsl24d1 36
  • 98 (a)
(Monodelphis domestica)
Mammalia RSL24D1 36
  • 93 (a)
(Ornithorhynchus anatinus)
Mammalia RSL24D1 36
  • 82 (a)
(Rattus norvegicus)
Mammalia Rsl24d1 35
  • 87.86 (n)
  • 98.15 (a)
(Gallus gallus)
Aves LOC768911 35
  • 80.95 (n)
  • 90.68 (a)
(Anolis carolinensis)
Reptilia RSL24D1 36
  • 86 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rsl24d1 35
  • 79.63 (n)
  • 88.27 (a)
(Danio rerio)
Actinopterygii rsl24d1 35
  • 74.95 (n)
  • 79.5 (a)
rsl24d1 36
  • 80 (a)
wufa95d02 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001545 35
  • 58.02 (n)
  • 59.26 (a)
fruit fly
(Drosophila melanogaster)
Insecta RpL24-like 35
  • 58.49 (n)
  • 60.38 (a)
RpL24-like 36
  • 51 (a)
(Caenorhabditis elegans)
Secernentea rpl-24.2 35
  • 57.68 (n)
  • 55.32 (a)
rpl-24.2 36
  • 48 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ADR346W 35
  • 56.31 (n)
  • 54.04 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RLP24 35
  • 58.02 (n)
  • 60.74 (a)
RLP24 36
  • 43 (a)
RLP24 38
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E09439g 35
  • 54.45 (n)
  • 54.04 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G44860 35
  • 59.91 (n)
  • 60.14 (a)
(Hordeum vulgare)
Liliopsida Hv.3722 35
(Zea mays)
Liliopsida Zm.7161 35
(Oryza sativa)
Liliopsida Os.2120 35
Os01g0514000 35
  • 55.28 (n)
  • 49.07 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU05235 35
  • 51.47 (n)
  • 47.79 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8868 36
  • 57 (a)
Species with no ortholog for RSL24D1:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RSL24D1 Gene

Gene Tree for RSL24D1 (if available)
Gene Tree for RSL24D1 (if available)

Paralogs for RSL24D1 Gene

Selected SIMAP similar genes for RSL24D1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with RSL24D1: view

No data available for Paralogs for RSL24D1 Gene

Variants for RSL24D1 Gene

Sequence variations from dbSNP and Humsavar for RSL24D1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs9300 -- 55,196,867(-) TATTT(C/T)TGTTC reference, synonymous-codon
rs10438 -- 55,181,607(+) CAGAA(G/T)GGTTA utr-variant-3-prime
rs13733 -- 55,196,906(-) GGGGT(C/T)ACACG utr-variant-5-prime
rs2277595 -- 55,196,999(+) AAGGC(A/G)AGCGT utr-variant-5-prime
rs3759861 -- 55,180,994(+) AGGGA(C/T)TGGTC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for RSL24D1 Gene

Variant ID Type Subtype PubMed ID
nsv525768 CNV Loss 19592680

Relevant External Links for RSL24D1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RSL24D1 Gene

Disorders for RSL24D1 Gene

Relevant External Links for RSL24D1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with RSL24D1: view

No data available for UniProtKB/Swiss-Prot for RSL24D1 Gene

Publications for RSL24D1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps. (PMID: 11707418) Saveanu C. … Fromont-Racine M. (EMBO J. 2001) 2 3
  3. Functional proteomic analysis of human nucleolus. (PMID: 12429849) Scherl A. … Diaz J.-J. (Mol. Biol. Cell 2002) 3 4
  4. Sequential protein association with nascent 60S ribosomal particles. (PMID: 12808088) Saveanu C. … Fromont-Racine M. (Mol. Cell. Biol. 2003) 2 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4

Products for RSL24D1 Gene

Sources for RSL24D1 Gene

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