Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RSL24D1 Gene

protein-coding   GIFtS: 57
GCID: GC15M055473

Ribosomal L24 Domain Containing 1

(Previous name: chromosome 15 open reading frame 15)
(Previous symbol: C15orf15)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ribosomal L24 Domain Containing 11 2     L302
C15orf151 2 3     RPL242
Ribosomal L24 Domain-Containing Protein 12 3     TVAS32
RPL24L2 3     Homolog Of Yeast Ribosomal Like Protein 242
RLP242 5     My024 Protein2
Chromosome 15 Open Reading Frame 151     Probable Ribosome Biogenesis Protein RLP242
60S Ribosomal Protein L30 Isolog2     Ribosomal Protein L24-Like3
HRP-L30-iso2     

External Ids:    HGNC: 184791   Entrez Gene: 511872   Ensembl: ENSG000001378767   OMIM: 6132625   UniProtKB: Q9UHA33   

Export aliases for RSL24D1 gene to outside databases

Previous GC identifers: GC15M053261 GC15M032299


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RSL24D1 Gene:
This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although
this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it
is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein
L30) and RPL30. The protein encoded by this gene localizes to the nucleolus and is thought to play a role in the
biogenesis of the 60S ribosomal subunit. The precise function of this gene is currently unknown. This gene
utilizes alternative polyadenylation signals and has multiple pseudogenes. (provided by RefSeq, Jul 2012)

GeneCards Summary for RSL24D1 Gene: 
RSL24D1 (ribosomal L24 domain containing 1) is a protein-coding gene. Diseases associated with RSL24D1 include diamond-blackfan anemia, and acne, and among its related super-pathways are Viral mRNA Translation.

UniProtKB/Swiss-Prot: RLP24_HUMAN, Q9UHA3
Function: Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S
particles (By similarity)

Gene Wiki entry for RSL24D1 (C15orf15) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.2  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RSL24D1 gene promoter:
         Elk-1   STAT1   STAT1beta   CUTL1   XBP-1   c-Ets-1   STAT1alpha   MEF-2A   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRSL24D1 promoter sequence
   Search SABiosciences Chromatin IP Primers for RSL24D1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RSL24D1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q21   Ensembl cytogenetic band:  15q21.3   HGNC cytogenetic band: 15q21

RSL24D1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RSL24D1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M055473:  view genomic region     (about GC identifiers)

Start:
55,473,004 bp from pter      End:
55,489,265 bp from pter
Size:
16,262 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RLP24_HUMAN, Q9UHA3 (See protein sequence)
Recommended Name: Probable ribosome biogenesis protein RLP24  
Size: 163 amino acids; 19621 Da
Subunit: Associated with nucleolar and cytoplasmic pre-60S particles. At the end of biogenesis it dissociates from
cytoplasmic pre-60S particles and is likely to be exchanged for its ribosomal homolog, RPL24 (By similarity)
Subcellular location: Nucleus, nucleolus
Secondary accessions: B2RD72 Q561V8 Q8N6S8 Q96B04 Q96C76 Q96HJ1

Explore the universe of human proteins at neXtProt for RSL24D1: NX_Q9UHA3

Explore proteomics data for RSL24D1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UHA3

  • RSL24D1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RSL24D1 Protein Expression
    REFSEQ proteins: NP_057388.1  
    ENSEMBL proteins: 
     ENSP00000260443   ENSP00000455291   ENSP00000454492  

    Human Recombinant Protein Products for RSL24D1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for RSL24D1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for RSL24D1
    GenScript Custom Purified and Recombinant Proteins Services for RSL24D1
    Novus Biologicals RSL24D1 Protein
    Novus Biologicals RSL24D1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RSL24D1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--

    RSL24D1 for ontologies           About GeneDecksing



    RSL24D1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for RSL24D1
    GenScript Custom Superior Antibodies Services for RSL24D1
    Novus Biologicals RSL24D1 Antibodies
    Abcam antibodies for RSL24D1
    Cloud-Clone Corp. Antibodies for RSL24D1 
    Search ThermoFisher Antibodies for RSL24D1
    LSBio Antibodies in human, mouse, rat for RSL24D1 

    Assay Products for RSL24D1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RSL24D1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RSL24D1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RSL24D1 
    Cloud-Clone Corp. CLIAs for RSL24D1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5 InterPro protein domains:
     IPR023441 Ribosomal_L24e_dom
     IPR023442 Ribosomal_L24e_CS
     IPR000988 Ribosomal_L24e_rel
     IPR024546 Ribosome_biogen_RLP24
     IPR011017 TRASH_dom

    Graphical View of Domain Structure for InterPro Entry Q9UHA3

    ProtoNet protein and cluster: Q9UHA3

    2 Blocks protein domains:
    IPB000988 Ribosomal protein L24E
    IPB011017 TRASH


    UniProtKB/Swiss-Prot: RLP24_HUMAN, Q9UHA3
    Similarity: Belongs to the ribosomal protein L24e family


    RSL24D1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RLP24_HUMAN, Q9UHA3
    Function: Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S
    particles (By similarity)

    Phenotypes:
         3 GenomeRNAi human phenotypes for RSL24D1:

     Decreased TP53 protein express  Increased Hepatitis C virus re  Increased S DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RSL24D1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RSL24D1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RSL24D1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RSL24D1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RSL24D1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate RSL24D1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RSL24D1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RSL24D1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RSL24D1
    Sirion Biotech Customized adenovirus for overexpression of RSL24D1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for RSL24D1 (see all 7)
    OriGene ORF clones in mouse, rat for RSL24D1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RSL24D1 (NM_016304)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RSL24D1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RSL24D1
    Sirion Biotech Customized lentivirus for stable overexpression of RSL24D1 
                         Customized lentivirus expression plasmids for stable overexpression of RSL24D1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RSL24D1
    Search LifeMap BioReagents cell lines for RSL24D1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RSL24D1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RSL24D1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Viral mRNA Translation
    Ribosome0.59

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for RSL24D1):
        Ribosome


    RSL24D1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RSL24D1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/147 Interacting proteins for RSL24D1 (Q9UHA32, 3 ENSP000002604434) via UniProtKB, MINT, STRING, and/or I2D (see all 147)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0042254ribosome biogenesis IEA--

    RSL24D1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RSL24D1 (RLP24)

    3 DrugBank Compounds for RSL24D1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    ANISOMYCIN-- --target--10592235
    Alpha-Hydroxy-Beta-Phenyl-Propionic Acid-- --target--10592235
    PUROMYCIN-- --target--10592235

    Search CenterWatch for drugs/clinical trials and news about RSL24D1 / RLP24

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RSL24D1 gene: 
    NM_016304.2  

    Unigene Cluster for RSL24D1:

    Ribosomal L24 domain containing 1
    Hs.274772  [show with all ESTs]
    Unigene Representative Sequence: BF244626
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000260443(uc002acn.3) ENST00000562993 ENST00000564344 ENST00000569386
    ENST00000565854 ENST00000562895
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RSL24D1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate RSL24D1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RSL24D1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RSL24D1
    Clone
    Products:
         
    OriGene clones in human, mouse for RSL24D1 (see all 7)
    OriGene ORF clones in mouse, rat for RSL24D1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RSL24D1 (NM_016304)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RSL24D1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RSL24D1
    Sirion Biotech Customized lentivirus for stable overexpression of RSL24D1 
                         Customized lentivirus expression plasmids for stable overexpression of RSL24D1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RSL24D1
    OriGene qSTAR qPCR primer pairs in human, mouse for RSL24D1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RSL24D1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RSL24D1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RSL24D1

    Additional mRNA sequence: 

    AB462502.1 AF060926.1 AF165521.1 AF201949.1 AF212226.1 AK055713.1 AK315431.1 BC005344.1 
    BC008409.1 BC008422.1 BC008449.1 BC008499.1 BC009593.1 BC009604.1 BC012913.1 BC014576.1 
    BC016312.1 BC016331.1 BC016725.1 BC016777.1 BC026266.1 BC026267.1 BC028672.1 BC035995.1 
    BC093067.1 CR457179.1 

    24/28 DOTS entries (see all 28):

    DT.92365361  DT.92470594  DT.100735712  DT.97860927  DT.100861119  DT.91794755  DT.92470571  DT.75146805 
    DT.91948152  DT.92470524  DT.95193401  DT.99926643  DT.120929646  DT.121028285  DT.40106713  DT.91644787 
    DT.91792935  DT.91892396  DT.91998103  DT.92060863  DT.92368002  DT.92470609  DT.95193522  DT.100011944 

    24/1387 AceView cDNA sequences (see all 1387):

    CA446566 BP376707 AI573041 AI766125 CA442954 AV715418 BM972346 BC016331 
    BX404157 BP338625 BF590325 AI689518 BM310822 BM761460 AI805098 CR457179 
    AA431846 BG257536 CB158420 AA828194 CR591767 BM310514 AW614180 AI539174 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RSL24D1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b
    SP1:              -           -                                 
    SP2:              -                                             
    SP3:                          -                                 


    ECgene alternative splicing isoforms for RSL24D1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RSL24D1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTAGTGATG
    RSL24D1 Expression
    About this image


    See RSL24D1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RSL24D1

    SOURCE GeneReport for Unigene cluster: Hs.274772
        SABiosciences Custom PCR Arrays for RSL24D1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for RSL24D1
    OriGene qSTAR qPCR primer pairs in human, mouse for RSL24D1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RSL24D1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RSL24D1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RSL24D1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RSL24D1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RSL24D1 gene from 10/28 species (see all 28)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rsl24d11 , 5 ribosomal L24 domain containing 11, 5 87.86(n)1
    98.77(a)1
      9 (40.10 cM)5
    2252151  NM_198609.21  NP_941011.11 
     731134265 
    chicken
    (Gallus gallus)
    Aves LOC7689111 probable ribosome biogenesis protein RLP24-like 80.95(n)
    90.68(a)
      768911  XM_001232072.2  XP_001232073.2 
    lizard
    (Anolis carolinensis)
    Reptilia RSL24D16
    Uncharacterized protein
    86(a)
    1 ↔ 1
    AAWZ02036658(3402-9934)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480383742   -- 80.83(n)    48038374 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa95d022 Danio rerio mRNA similar to chromosome 15 open reading more 75.44(n)    BC051780.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL24-like1 Ribosomal protein L24-like 58.49(n)
    60.38(a)
      41372  NM_141816.3  NP_650073.1 
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-24.21 Protein RPL-24.2 57.68(n)
    55.32(a)
      172815  NM_060171.3  NP_492572.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RLP24(YLR009W)4
    RLP241
    Essential protein with similarity to Rpl24Ap and Rpl24Bp, more4
    Rlp24p1
    55.28(n)1
    54.66(a)1
      12(166537-167136)4
    8506951, 4  NP_013109.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G448601 large subunit ribosomal protein L24e 59.38(n)
    59.6(a)
      819095  NM_130050.4  NP_182013.1 
    rice
    (Oryza sativa)
    Liliopsida Os.21202 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 78.63(n)    AK073707.1 


    ENSEMBL Gene Tree for RSL24D1 (if available)
    TreeFam Gene Tree for RSL24D1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RSL24D1 gene
    1 SIMAP similar gene for RSL24D1 using alignment to 3 protein entries:     RLP24_HUMAN (see all proteins):
    RPL24

    RSL24D1 for paralogs           About GeneDecksing


    5/19 Pseudogenes.org Pseudogenes for RSL24D1 (see all 19)
    PGOHUM00000242367 PGOHUM00000239490 PGOHUM00000239903 PGOHUM00000248205 PGOHUM00000249124


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/414 SNPs in RSL24D1 are shown (see all 414)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1454477081,2
    --55473042(+) AATACA/GGTATG 1 -- ds50010--------
    rs601054181,2
    C,F--55473157(+) CCACAT/CTGGAA 1 -- ds50012Minor allele frequency- C:0.04WA 120
    rs1895942691,2
    --55473184(+) CTTGGC/TCCAGG 1 -- ds50010--------
    rs611914951,2
    C,F--55473187(+) GGTCCA/GGGGAC 1 -- ds50012Minor allele frequency- G:0.07WA 120
    rs37598611,2
    C,F,A,H--55473192(+) AGGGAC/TTGGTC 1 -- ds500124Minor allele frequency- T:0.22EA NA NS WA CSA 3726
    rs129173621,2
    C,F,H--55473306(+) ACCATT/AATGCA 1 -- ds50015Minor allele frequency- A:0.00NS EA NA 422
    rs1851330801,2
    --55473312(+) ATGCAA/TACTGA 1 -- ds50010--------
    rs1908232931,2
    --55473357(+) TAAACA/GATGTA 1 -- ds50010--------
    rs1819615781,2
    --55473359(+) AACAAC/TGTAAA 1 -- ds50010--------
    rs1149877791,2
    C,F--55473391(+) AGTATC/ATATTT 1 -- ds50011Minor allele frequency- A:0.09WA 118

    HapMap Linkage Disequilibrium report for RSL24D1 (55473004 - 55489265 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for RSL24D1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv525768CNV Loss19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RSL24D1
    DNA2.0 Custom Variant and Variant Library Synthesis for RSL24D1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613262    OMIM disorders: --

    6 diseases for RSL24D1:    About MalaCards
    diamond-blackfan anemia    acne    vasculitis    anemia
    hepatitis b    hepatitis


    RSL24D1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RSL24D1
    Human Genome Epidemiology (HuGE) Navigator: RSL24D1 (1 document)

    Export disorders for RSL24D1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RSL24D1 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with RSL24D1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Sequential protein association with nascent 60S ribosomal particles. (PubMed id 12808088)1, 3 Saveanu C....Fromont-Racine M. (2003)
    4. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
    5. Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps. (PubMed id 11707418)1, 3 Saveanu C....Fromont-Racine M. (2001)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women. (PubMed id 21507922)1 Ramsuran V....Ndung'u T. (2011)
    10. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51187 HGNC: 18479 AceView: C15orf15 Ensembl:ENSG00000137876 euGenes: HUgn51187
    ECgene: RSL24D1 Kegg: 51187 H-InvDB: RSL24D1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RSL24D1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RSL24D1 gene:
    Search GeneIP for patents involving RSL24D1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for RSL24D1  
     OriGene qPCR primer pairs and template standards for RSL24D1   OriGene Protein Over-expression Lysate for RSL24D1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for RSL24D1  
     OriGene qSTAR qPCR primer pairs in human, mouse for RSL24D1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for RSL24D1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RSL24D1   OriGene Custom Protein Services for RSL24D1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RSL24D1
     QIAGEN SeqTarget long-range PCR primers for resequencing RSL24D1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RSL24D1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RSL24D1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RSL24D1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RSL24D1
     GenScript Custom Purified and Recombinant Proteins Services for RSL24D1 GenScript cDNA clones with any tag delivered in your preferred vector for RSL24D1
     GenScript Custom Assay Services for RSL24D1 GenScript Custom Superior Antibodies Services for RSL24D1
     GenScript Custom overexpressing Cell Line Services for RSL24D1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in RSL24D1 promoter
     Search Chromatin IP Primers for RSL24D1
     RT2 qPCR Primer Assay in human, mouse, rat RSL24D1
     Search GNC Networks for RSL24D1
     SABiosciences Custom PCR Arrays for RSL24D1
     Search Tocris compounds for RSL24D1 (RLP24)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     RSL24D1 antibodies
     RSL24D1 proteins
     RSL24D1 lysates
     Antibodies for RSL24D1
     See all of Abcam's Antibodies, Kits and Proteins for RSL24D1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for RSL24D1
     Antibodies for RSL24D1
     ELISAs for RSL24D1
     CLIAs for RSL24D1
     Search LifeMap BioReagents cell lines for RSL24D1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RSL24D1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for RSL24D1
     SwitchGear Promoter luciferase reporter plasmids for RSL24D1
     Search ThermoFisher Antibodies for RSL24D1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RSL24D1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for RSL24D1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RSL24D1
    Customized:
     lentivirus for stable overexpression of RSL24D1
     lentivirus expression plasmids for stable overexpression of RSL24D1
     adenovirus for overexpression of RSL24D1
     LSBio Antibodies in human, mouse, rat for RSL24D1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RSL24D1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4