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Aliases for RSBN1L Gene

Aliases for RSBN1L Gene

  • Round Spermatid Basic Protein 1 Like 2 3 5
  • Round Spermatid Basic Protein 1-Like 2

External Ids for RSBN1L Gene

Previous GeneCards Identifiers for RSBN1L Gene

  • GC07P076970
  • GC07P077163
  • GC07P077325
  • GC07P071928

Summaries for RSBN1L Gene

GeneCards Summary for RSBN1L Gene

RSBN1L (Round Spermatid Basic Protein 1 Like) is a Protein Coding gene. An important paralog of this gene is RSBN1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RSBN1L Gene

Genomics for RSBN1L Gene

Regulatory Elements for RSBN1L Gene

Enhancers for RSBN1L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F077719 0.9 Ensembl ENCODE 13.3 +24.2 24175 1.6 ZNF362 ZNF146 RAD21 OSR2 ZFHX2 GLIS1 PRDM10 ZNF600 PRDM1 SP7 APTR PTPN12 RSBN1L PHTF2 TMEM60
GH07F077717 0.6 Ensembl 13.3 +21.5 21475 0.2 KLF1 RSBN1L APTR PHTF2 TMEM60 PTPN12
GH07F077718 0.6 Ensembl 13.3 +22.5 22475 0.2 ZNF335 SCRT2 ZBTB17 RSBN1L APTR PHTF2 TMEM60 PTPN12
GH07F077722 0.5 Ensembl 13.3 +26.0 25975 0.4 HDGF USF1 BMI1 ZIC2 POLR2A EED ZNF143 ETV6 CREM STAT1 APTR RSBN1L PHTF2 TMEM60 PTPN12
GH07F077723 0.7 Ensembl 13.3 +26.6 26575 0.4 TRIM22 NBN ZNF18 GABPA APTR RSBN1L PHTF2 TMEM60 PTPN12
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around RSBN1L on UCSC Golden Path with GeneCards custom track

Promoters for RSBN1L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for RSBN1L Gene

77,696,426 bp from pter
77,783,022 bp from pter
86,597 bases
Plus strand

Genomic View for RSBN1L Gene

Genes around RSBN1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RSBN1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RSBN1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RSBN1L Gene

Proteins for RSBN1L Gene

  • Protein details for RSBN1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Round spermatid basic protein 1-like protein
    Protein Accession:
    Secondary Accessions:
    • C9K0P1
    • Q6ZS58
    • Q6ZVI9
    • Q86X48

    Protein attributes for RSBN1L Gene

    846 amino acids
    Molecular mass:
    94870 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH46353.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAC85872.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for RSBN1L Gene


neXtProt entry for RSBN1L Gene

Post-translational modifications for RSBN1L Gene

  • Ubiquitination at Lys 548
  • Modification sites at PhosphoSitePlus

Other Protein References for RSBN1L Gene

No data available for DME Specific Peptides for RSBN1L Gene

Domains & Families for RSBN1L Gene

Protein Domains for RSBN1L Gene


Suggested Antigen Peptide Sequences for RSBN1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the round spermatid basic protein 1 family.
  • Belongs to the round spermatid basic protein 1 family.
genes like me logo Genes that share domains with RSBN1L: view

No data available for Gene Families for RSBN1L Gene

Function for RSBN1L Gene

genes like me logo Genes that share phenotypes with RSBN1L: view

Animal Model Products

miRNA for RSBN1L Gene

miRTarBase miRNAs that target RSBN1L

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RSBN1L Gene

Localization for RSBN1L Gene

Subcellular locations from UniProtKB/Swiss-Prot for RSBN1L Gene

Subcellular locations from

Jensen Localization Image for RSBN1L Gene COMPARTMENTS Subcellular localization image for RSBN1L gene
Compartment Confidence
nucleus 5
cytosol 2
plasma membrane 2

Gene Ontology (GO) - Cellular Components for RSBN1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with RSBN1L: view

Pathways & Interactions for RSBN1L Gene

SuperPathways for RSBN1L Gene

No Data Available

Gene Ontology (GO) - Biological Process for RSBN1L Gene


No data available for Pathways by source and SIGNOR curated interactions for RSBN1L Gene

Transcripts for RSBN1L Gene

Unigene Clusters for RSBN1L Gene

Round spermatid basic protein 1-like:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RSBN1L Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c
SP1: -
SP2: - -

Relevant External Links for RSBN1L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RSBN1L Gene

mRNA expression in normal human tissues for RSBN1L Gene

Protein differential expression in normal tissues from HIPED for RSBN1L Gene

This gene is overexpressed in Lung (54.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RSBN1L Gene

Protein tissue co-expression partners for RSBN1L Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of RSBN1L Gene:


SOURCE GeneReport for Unigene cluster for RSBN1L Gene:

genes like me logo Genes that share expression patterns with RSBN1L: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RSBN1L Gene

Orthologs for RSBN1L Gene

This gene was present in the common ancestor of animals.

Orthologs for RSBN1L Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RSBN1L 34 35
  • 99.64 (n)
(Canis familiaris)
Mammalia RSBN1L 34 35
  • 94.51 (n)
(Bos Taurus)
Mammalia RSBN1L 34 35
  • 92.17 (n)
(Monodelphis domestica)
Mammalia RSBN1L 35
  • 89 (a)
(Ornithorhynchus anatinus)
Mammalia RSBN1L 35
  • 86 (a)
(Mus musculus)
Mammalia Rsbn1l 34 16 35
  • 85.62 (n)
(Rattus norvegicus)
Mammalia Rsbn1l 34
  • 84.83 (n)
(Gallus gallus)
Aves RSBN1L 34 35
  • 81.94 (n)
(Anolis carolinensis)
Reptilia RSBN1L 35
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rsbn1l 34
  • 72.61 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG10600 35
  • 16 (a)
(Caenorhabditis elegans)
Secernentea dpy-21 35
  • 11 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.789 35
  • 54 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.8474 34
Species where no ortholog for RSBN1L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for RSBN1L Gene

Gene Tree for RSBN1L (if available)
Gene Tree for RSBN1L (if available)

Paralogs for RSBN1L Gene

Paralogs for RSBN1L Gene

(1) SIMAP similar genes for RSBN1L Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with RSBN1L: view

Variants for RSBN1L Gene

Sequence variations from dbSNP and Humsavar for RSBN1L Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10215847 -- 77,701,040(+) atagt(C/T)tcagc intron-variant
rs10216002 -- 77,699,012(+) TAACA(A/C)GTGGT intron-variant, upstream-variant-2KB
rs10224930 -- 77,772,874(+) AGGTA(A/T)AGATT intron-variant
rs10225586 -- 77,752,055(+) ACTAT(C/G)TAATA intron-variant
rs10233055 -- 77,747,005(+) ttgag(G/T)gcttg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RSBN1L Gene

Variant ID Type Subtype PubMed ID
nsv1140809 CNV deletion 24896259
nsv365896 CNV insertion 16902084
nsv831039 CNV gain 17160897

Variation tolerance for RSBN1L Gene

Residual Variation Intolerance Score: 16.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.53; 55.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RSBN1L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RSBN1L Gene

Disorders for RSBN1L Gene

Relevant External Links for RSBN1L

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RSBN1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RSBN1L Gene

Publications for RSBN1L Gene

  1. New loci associated with kidney function and chronic kidney disease. (PMID: 20383146) KAPttgen A. … Fox C.S. (Nat. Genet. 2010) 3 46 64
  2. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 3 64
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64

Products for RSBN1L Gene

Sources for RSBN1L Gene

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