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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RRS1 Gene

protein-coding   GIFtS: 51
GCID: GC08P067341

RRS1 Ribosome Biogenesis Regulator Homolog (S. Cerevisiae)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RRS1 Ribosome Biogenesis Regulator Homolog (S. Cerevisiae)1 2     Ribosome Biogenesis Regulatory Protein RRS1 Homolog2
Homolog Of Yeast Ribosome Biogenesis Regulator2     KIAA01123
Homolog Of Yeast Ribosome Biogenesis Regulatory Protein RRS12     RRR3
Ribosome Biogenesis Regulatory Protein Homolog2     FSDR25

External Ids:    HGNC: 170831   Entrez Gene: 232122   Ensembl: ENSG000001790417   OMIM: 6115785   UniProtKB: Q150503   

Export aliases for RRS1 gene to outside databases

Previous GC identifers: GC08P066460 GC08P067280 GC08P067064 GC08P067391 GC08P067503 GC08P062831


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RRS1 Gene: 
RRS1 (RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with RRS1 include salpingitis, and pelvic inflammatory disease. GO annotations related to this gene include molecular_function.

UniProtKB/Swiss-Prot: RRS1_HUMAN, Q15050
Function: Involved in ribosome biogenesis (By similarity)

Gene Wiki entry for RRS1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_008183.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RRS1 gene promoter:
         HEN1   GR   NRF-2   AML1a   GR-beta   Nkx2-5   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRRS1 promoter sequence
   Search SABiosciences Chromatin IP Primers for RRS1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RRS1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q13.1   Ensembl cytogenetic band:  8q13.1   HGNC cytogenetic band: 8q12.3

RRS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RRS1 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P067341:  view genomic region     (about GC identifiers)

Start:
67,341,263 bp from pter      End:
67,342,968 bp from pter
Size:
1,706 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RRS1_HUMAN, Q15050 (See protein sequence)
Recommended Name: Ribosome biogenesis regulatory protein homolog  
Size: 365 amino acids; 41193 Da
Subcellular location: Nucleus, nucleolus
Sequence caution: Sequence=BAA04948.1; Type=Erroneous initiation;
Secondary accessions: Q9BUX8

Explore the universe of human proteins at neXtProt for RRS1: NX_Q15050

Explore proteomics data for RRS1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q15050

  • RRS1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RRS1 Protein Expression
    REFSEQ proteins: NP_055984.1  
    ENSEMBL proteins: 
     ENSP00000322396  

    Human Recombinant Protein Products for RRS1: 
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    Novus Biologicals RRS1 Protein
    Novus Biologicals RRS1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RRS1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000794condensed nuclear chromosome IDA19465021
    GO:0005634nucleus ----
    GO:0005730nucleolus IDA19465021
    GO:0005783endoplasmic reticulum IEA--

    RRS1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. ELISAs for RRS1 
    Cloud-Clone Corp. CLIAs for RRS1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR007023 Ribosom_reg

    Graphical View of Domain Structure for InterPro Entry Q15050

    ProtoNet protein and cluster: Q15050

    1 Blocks protein domain: IPB007023 Ribosomal biogenesis regulatory protein

    UniProtKB/Swiss-Prot: RRS1_HUMAN, Q15050
    Similarity: Belongs to the RRS1 family


    RRS1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RRS1_HUMAN, Q15050
    Function: Involved in ribosome biogenesis (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding ----
         
    RRS1 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for RRS1:
     Decreased TP53 protein express  High actin ratio cells  Nuclear 60S biogenesis defects  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RRS1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RRS1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RRS1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RRS1 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RRS1
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate RRS1:
    hsa-miR-299-5p hsa-miR-3143 hsa-miR-548c-3p hsa-miR-3714
    SwitchGear 3'UTR luciferase reporter plasmidRRS1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for RRS1
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    GenScript: all cDNA clones in your preferred vector: RRS1 (NM_015169)
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RRS1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RRS1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/43 Interacting proteins for RRS1 (Q150502, 3 ENSP000003223964) via UniProtKB, MINT, STRING, and/or I2D (see all 43)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APPBP2Q926242, 3, ENSP000000831824MINT-67461 I2D: score=5 STRING: ENSP00000083182
    LYARQ9NX583, ENSP000003459174I2D: score=1 STRING: ENSP00000345917
    GABARAPO951663I2D: score=1 
    KBTBD7Q8WVZ93I2D: score=1 
    ULK2Q8IYT83I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007080mitotic metaphase plate congression IMP19465021
    GO:0042254ribosome biogenesis IEA--

    RRS1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RRS1

    Search CenterWatch for drugs/clinical trials and news about RRS1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RRS1 gene: 
    NM_015169.3  

    Unigene Cluster for RRS1:

    RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
    Hs.71827  [show with all ESTs]
    Unigene Representative Sequence: NM_015169
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000320270(uc003xwa.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RRS1
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate RRS1:
    hsa-miR-299-5p hsa-miR-3143 hsa-miR-548c-3p hsa-miR-3714
    SwitchGear 3'UTR luciferase reporter plasmidRRS1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RRS1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RRS1
    Clone
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    OriGene clones in human, mouse for RRS1 (see all 7)
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    GenScript: all cDNA clones in your preferred vector: RRS1 (NM_015169)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RRS1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RRS1
    Sirion Biotech Customized lentivirus for stable overexpression of RRS1 
                         Customized lentivirus expression plasmids for stable overexpression of RRS1 
    Primer
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    OriGene qPCR primer pairs and template standards for RRS1
    OriGene qSTAR qPCR primer pairs in human, mouse for RRS1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RRS1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RRS1

    Additional mRNA sequence: 

    AK024716.1 BC001811.2 BC013043.2 D25218.1 

    5 DOTS entries:

    DT.412746  DT.97843905  DT.100701289  DT.99934485  DT.121477851 

    24/133 AceView cDNA sequences (see all 133):

    AI190957 CR592451 BM555759 CR625499 AI332995 CA431075 BP338492 AW471485 
    CR622558 D25218 BM849202 BF939144 AW614528 BQ001335 BC001811 BP341220 
    BC013043 H22075 BU163897 BF058145 CA422798 AI674449 AL531971 BG109137 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RRS1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACAGCAAGA
    RRS1 Expression
    About this image


    See RRS1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RRS1

    SOURCE GeneReport for Unigene cluster: Hs.71827
        SABiosciences Custom PCR Arrays for RRS1
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RRS1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RRS1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RRS1 gene from 8/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rrs11 , 5 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)1, 5 87.95(n)1
    90.68(a)1
      1 (2.08 cM)5
    590141  NM_021511.21  NP_067486.21 
     95454085 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.151902 Xenopus laevis transcribed sequence with weak similarity more 74.85(n)    BQ731831.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj66c042 wufj66c04 74.19(n)   337399  BC055615.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG324091 CG32409 52.75(n)
    45.35(a)
      318016  NM_168144.2  NP_729108.2 
    worm
    (Caenorhabditis elegans)
    Secernentea C15H11.93
    rrbs-11
    Human HA0609 protein like3
    Protein RRBS-11
    45(a)3
    49.62(n)1
    43.73(a)1
      V(14426493-14427601)3
    1799421  NM_074172.31  NP_506573.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RRS1(YOR294W)4
    RRS11
    Essential protein that binds ribosomal protein L11; more4
    Rrs1p1
    48.73(n)1
    43.86(a)1
      15(868340-868951)4
    8544691, 4  NP_014937.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G379901 ribosome biogenesis regulatory protein-like protein 47.08(n)
    40.88(a)
      818377  NM_129356.3  NP_565878.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g06851001 hypothetical protein 48.39(n)
    40.5(a)
      4337459  NM_001060850.1  NP_001054315.1 


    ENSEMBL Gene Tree for RRS1 (if available)
    TreeFam Gene Tree for RRS1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    3 SNPs in RRS1 are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0204844
    ----see VAR_0204842 R L mis40--------
    VAR_0518874
    ----see VAR_0518872 Q H mis40--------
    VAR_0518884
    ----see VAR_0518882 K R mis40--------

    HapMap Linkage Disequilibrium report for RRS1 (67341263 - 67342968 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RRS1: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RRS1
    DNA2.0 Custom Variant and Variant Library Synthesis for RRS1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611578    OMIM disorders: --

    3 diseases for RRS1:    About MalaCards
    salpingitis    pelvic inflammatory disease    huntington's disease


    RRS1 for disorders           About GeneDecksing


    Export disorders for RRS1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RRS1 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with RRS1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7788527)1, 2, 3 Nagase T....Kotani H. (1995)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
    4. RRS1, a conserved essential gene, encodes a novel regulatory protein required for ribosome biogenesis in Saccharomyces cerevisiae. (PubMed id 10688653)1, 3 Tsuno A....Mizuta K. (2000)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    7. A catalogue of putative HIV-1 protease host cell subst rates. (PubMed id 22944692)1 Impens F....Gevaert K. (2012)
    8. Integrative analysis of the ubiquitin proteome isolat ed using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (2011)
    9. Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (2011)
    10. Quantitative nanoproteomics for protein complexes (QNa noPX) related to estrogen transcriptional action. (PubMed id 19805454)1 Cheng P.C....Chen S.H. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23212 HGNC: 17083 AceView: RRS1 Ensembl:ENSG00000179041 euGenes: HUgn23212
    ECgene: RRS1 H-InvDB: RRS1

    (According to HUGE)
    About This Section
    HUGE: KIAA0112

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RRS1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RRS1 gene:
    Search GeneIP for patents involving RRS1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
    transforming growth factor, beta 1
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