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Aliases for RRS1 Gene

Aliases for RRS1 Gene

  • RRS1 Ribosome Biogenesis Regulator Homolog (S. Cerevisiae) 2 3
  • KIAA0112 4
  • C9orf4 6
  • FRRS1L 6
  • CG6 6
  • RRR 4

External Ids for RRS1 Gene

Previous GeneCards Identifiers for RRS1 Gene

  • GC08P067280
  • GC08P067064
  • GC08P067391
  • GC08P067503
  • GC08P067341
  • GC08P062831

Summaries for RRS1 Gene

GeneCards Summary for RRS1 Gene

RRS1 (RRS1 Ribosome Biogenesis Regulator Homolog (S. Cerevisiae)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for RRS1 Gene

  • Involved in ribosome biogenesis.

Gene Wiki entry for RRS1 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RRS1 Gene

Genomics for RRS1 Gene

Regulatory Elements for RRS1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for RRS1 Gene

66,429,028 bp from pter
66,430,733 bp from pter
1,706 bases
Plus strand

Genomic View for RRS1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RRS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RRS1 Gene

Proteins for RRS1 Gene

  • Protein details for RRS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ribosome biogenesis regulatory protein homolog
    Protein Accession:
    Secondary Accessions:
    • Q9BUX8

    Protein attributes for RRS1 Gene

    365 amino acids
    Molecular mass:
    41193 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA04948.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for RRS1 Gene

Proteomics data for RRS1 Gene at MOPED

Post-translational modifications for RRS1 Gene

Other Protein References for RRS1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RRS1 Gene

Domains for RRS1 Gene

Protein Domains for RRS1 Gene

Suggested Antigen Peptide Sequences for RRS1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q15050
  • Belongs to the RRS1 family.
genes like me logo Genes that share domains with RRS1: view

No data available for Gene Families for RRS1 Gene

Function for RRS1 Gene

Molecular function for RRS1 Gene

UniProtKB/Swiss-Prot Function: Involved in ribosome biogenesis.

Gene Ontology (GO) - Molecular Function for RRS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RRS1: view
genes like me logo Genes that share phenotypes with RRS1: view

Animal Model Products

CRISPR Products

miRNA for RRS1 Gene

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RRS1 Gene

Localization for RRS1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RRS1 Gene

Nucleus, nucleolus.

Subcellular locations from

Jensen Localization Image for RRS1 Gene COMPARTMENTS Subcellular localization image for RRS1 gene
Compartment Confidence
nucleus 5
cytosol 2
endoplasmic reticulum 2

Gene Ontology (GO) - Cellular Components for RRS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000794 condensed nuclear chromosome IDA 19465021
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
GO:0005783 endoplasmic reticulum IEA --
genes like me logo Genes that share ontologies with RRS1: view

Pathways for RRS1 Gene

SuperPathways for RRS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RRS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002244 hematopoietic progenitor cell differentiation IEA --
GO:0007080 mitotic metaphase plate congression IMP 19465021
GO:0042254 ribosome biogenesis IEA --
genes like me logo Genes that share ontologies with RRS1: view

No data available for Pathways by source for RRS1 Gene

Transcripts for RRS1 Gene

mRNA/cDNA for RRS1 Gene

(133) Selected AceView cDNA sequences:
(4) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RRS1 Gene

RRS1 ribosome biogenesis regulator homolog (S. cerevisiae):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RRS1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RRS1 Gene

No ASD Table

Relevant External Links for RRS1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RRS1 Gene

mRNA expression in normal human tissues for RRS1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RRS1 Gene

SOURCE GeneReport for Unigene cluster for RRS1 Gene Hs.71827

genes like me logo Genes that share expressions with RRS1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RRS1 Gene

Orthologs for RRS1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RRS1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RRS1 35
  • 94.41 (n)
  • 91.47 (a)
RRS1 36
  • 93 (a)
(Bos Taurus)
Mammalia RRS1 35
  • 89.77 (n)
  • 93.7 (a)
RRS1 36
  • 94 (a)
(Canis familiaris)
Mammalia RRS1 35
  • 90.41 (n)
  • 94.25 (a)
RRS1 36
  • 94 (a)
(Mus musculus)
Mammalia Rrs1 35
  • 87.95 (n)
  • 90.68 (a)
Rrs1 16
Rrs1 36
  • 91 (a)
(Monodelphis domestica)
Mammalia RRS1 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia RRS1 36
  • 70 (a)
(Rattus norvegicus)
Mammalia Rrs1 35
  • 87.12 (n)
  • 91.51 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15190 35
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.641 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2989 35
(Danio rerio)
Actinopterygii rrs1 35
  • 63.59 (n)
  • 65.61 (a)
rrs1 36
  • 62 (a)
wufj66c04 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP006808 35
  • 51.84 (n)
  • 43.18 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG32409 35
  • 54.05 (n)
  • 46.6 (a)
CG32409 36
  • 44 (a)
(Caenorhabditis elegans)
Secernentea rrbs-1 35
  • 50.86 (n)
  • 47.81 (a)
rrbs-1 36
  • 41 (a)
C15H11.9 37
  • 45 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ABL014C 35
  • 55.56 (n)
  • 46.2 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RRS1 35
  • 48.34 (n)
  • 43.86 (a)
RRS1 36
  • 37 (a)
RRS1 38
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0B13046g 35
  • 50.99 (n)
  • 43.45 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G37990 35
  • 46.91 (n)
  • 40.73 (a)
(Oryza sativa)
Liliopsida Os04g0685100 35
  • 48.96 (n)
  • 41.39 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU08121 35
  • 51.88 (n)
  • 45.97 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes rrs1 35
  • 47.01 (n)
  • 45.52 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.984 36
  • 47 (a)
Species with no ortholog for RRS1:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RRS1 Gene

Gene Tree for RRS1 (if available)
Gene Tree for RRS1 (if available)

Paralogs for RRS1 Gene

No data available for Paralogs for RRS1 Gene

Variants for RRS1 Gene

Sequence variations from dbSNP and Humsavar for RRS1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
VAR_020484 -
VAR_051887 -
VAR_051888 -

Relevant External Links for RRS1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RRS1 Gene

Disorders for RRS1 Gene

No disorders were found for RRS1 Gene.

No data available for UniProtKB/Swiss-Prot for RRS1 Gene

Publications for RRS1 Gene

  1. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 7788527) Nagase T. … Nomura N. (DNA Res. 1995) 2 3 4
  2. RRS1, a conserved essential gene, encodes a novel regulatory protein required for ribosome biogenesis in Saccharomyces cerevisiae. (PMID: 10688653) Tsuno A. … Mizuta K. (Mol. Cell. Biol. 2000) 2 3
  3. Functional proteomic analysis of human nucleolus. (PMID: 12429849) Scherl A. … Diaz J.-J. (Mol. Biol. Cell 2002) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Nucleolar proteome dynamics. (PMID: 15635413) Andersen J.S. … Mann M. (Nature 2005) 3

Products for RRS1 Gene

Sources for RRS1 Gene

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