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Aliases for RRP36 Gene

Aliases for RRP36 Gene

  • Ribosomal RNA Processing 36 Homolog (S. Cerevisiae) 2 3
  • C6orf153 3 4 6
  • Ribosomal RNA Processing Protein 36 Homolog 3
  • Chromosome 6 Open Reading Frame 153 2
  • RNA Processing Factor 3
  • DJ20C7.4 3

External Ids for RRP36 Gene

Previous HGNC Symbols for RRP36 Gene

  • C6orf153

Previous GeneCards Identifiers for RRP36 Gene

  • GC06P042993
  • GC06P042706
  • GC06P042995
  • GC06P043000
  • GC06P043002
  • GC06P043009

Summaries for RRP36 Gene

Entrez Gene Summary for RRP36 Gene

  • RRP36 functions at an early stage in the processing of 35S preribosomal RNA into the mature 18S species (Gerus et al., 2010 [PubMed 20038530]).[supplied by OMIM, Jul 2010]

GeneCards Summary for RRP36 Gene

RRP36 (Ribosomal RNA Processing 36 Homolog (S. Cerevisiae)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for RRP36 Gene

  • Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RRP36 Gene

Genomics for RRP36 Gene

Genomic Location for RRP36 Gene

Start:
43,021,645 bp from pter
End:
43,034,156 bp from pter
Size:
12,512 bases
Orientation:
Plus strand

Genomic View for RRP36 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RRP36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RRP36 Gene

No data available for Regulatory Elements for RRP36 Gene

Proteins for RRP36 Gene

  • Protein details for RRP36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96EU6-RRP36_HUMAN
    Recommended name:
    Ribosomal RNA processing protein 36 homolog
    Protein Accession:
    Q96EU6
    Secondary Accessions:
    • Q9BRF6
    • Q9P0C8

    Protein attributes for RRP36 Gene

    Size:
    259 amino acids
    Molecular mass:
    29823 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Meningioma antigen
    SequenceCaution:
    • Sequence=AAH06293.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for RRP36 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RRP36 Gene

Proteomics data for RRP36 Gene at MOPED

Post-translational modifications for RRP36 Gene

  • Ubiquitination at Lys225
  • Modification sites at PhosphoSitePlus

Other Protein References for RRP36 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RRP36 Gene

Domains for RRP36 Gene

Protein Domains for RRP36 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for RRP36 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96EU6

UniProtKB/Swiss-Prot:

RRP36_HUMAN :
  • Q96EU6
Family:
  • Belongs to the RRP36 family.
genes like me logo Genes that share domains with RRP36: view

No data available for Gene Families for RRP36 Gene

Function for RRP36 Gene

Molecular function for RRP36 Gene

UniProtKB/Swiss-Prot Function: Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA.

Gene Ontology (GO) - Molecular Function for RRP36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RRP36: view

Animal Model Products

CRISPR Products

miRNA for RRP36 Gene

miRTarBase miRNAs that target RRP36

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RRP36

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for RRP36 Gene

Localization for RRP36 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RRP36 Gene

Nucleus, nucleolus. Note=Concentrated in the fibrillar region of the nucleolus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RRP36 Gene COMPARTMENTS Subcellular localization image for RRP36 gene
Compartment Confidence
nucleus 5
cytosol 1

Gene Ontology (GO) - Cellular Components for RRP36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
GO:0030686 90S preribosome IBA --
genes like me logo Genes that share ontologies with RRP36: view

Pathways for RRP36 Gene

SuperPathways for RRP36 Gene

No Data Available

Interacting Proteins for RRP36 Gene

Gene Ontology (GO) - Biological Process for RRP36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA --
GO:0006364 rRNA processing IDA 20038530
GO:0042274 ribosomal small subunit biogenesis IDA 20038530
genes like me logo Genes that share ontologies with RRP36: view

No data available for Pathways by source for RRP36 Gene

Transcripts for RRP36 Gene

mRNA/cDNA for RRP36 Gene

Unigene Clusters for RRP36 Gene

Ribosomal RNA processing 36 homolog (S. cerevisiae):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RRP36

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RRP36 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b
SP1: -
SP2: - - - -
SP3:
SP4:

Relevant External Links for RRP36 Gene

GeneLoc Exon Structure for
RRP36
ECgene alternative splicing isoforms for
RRP36

Expression for RRP36 Gene

mRNA expression in normal human tissues for RRP36 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RRP36 Gene

SOURCE GeneReport for Unigene cluster for RRP36 Gene Hs.309231

genes like me logo Genes that share expressions with RRP36: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RRP36 Gene

Orthologs for RRP36 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RRP36 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RRP36 35
  • 98.84 (n)
  • 98.84 (a)
RRP36 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RRP36 35
  • 85.79 (n)
  • 85.25 (a)
dog
(Canis familiaris)
Mammalia RRP36 35
  • 89.8 (n)
  • 88.79 (a)
mouse
(Mus musculus)
Mammalia Rrp36 35
  • 83.41 (n)
  • 85.78 (a)
Rrp36 16
Rrp36 36
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RRP36 36
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rrp36 35
  • 85.56 (n)
  • 88.02 (a)
chicken
(Gallus gallus)
Aves LOC100858699 35
  • 59.82 (n)
  • 55.8 (a)
RRP36 36
  • 52 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RRP36 36
  • 59 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3045 35
zebrafish
(Danio rerio)
Actinopterygii rrp36 35
  • 58.41 (n)
  • 49.56 (a)
rrp36 36
  • 35 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002333 35
  • 44.92 (n)
  • 34.29 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8461 35
  • 49.53 (n)
  • 38.32 (a)
CG8461 36
  • 29 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea T22H9.1 36
  • 14 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RRP36 38
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G12650 35
  • 48.48 (n)
  • 43.03 (a)
rice
(Oryza sativa)
Liliopsida Os09g0525200 35
  • 47.12 (n)
  • 37.02 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 34 (a)
OneToOne
Species with no ortholog for RRP36:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RRP36 Gene

ENSEMBL:
Gene Tree for RRP36 (if available)
TreeFam:
Gene Tree for RRP36 (if available)

Paralogs for RRP36 Gene

No data available for Paralogs for RRP36 Gene

Variants for RRP36 Gene

Sequence variations from dbSNP and Humsavar for RRP36 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs942044 -- 43,023,470(+) gtggg(C/T)ggatc intron-variant
rs1138141 -- 43,027,473(+) CTGAA(A/G)AAATG reference, synonymous-codon
rs2395959 -- 43,022,619(+) gtaga(A/G)acaag intron-variant
rs3077952 -- 43,022,587(+) ggttt(A/G)tttat intron-variant
rs3749903 - 43,025,087(-) TAGAA(C/G)CTTGT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for RRP36 Gene

Variant ID Type Subtype PubMed ID
nsv462927 CNV Loss 19166990
nsv462930 CNV Loss 19166990
nsv885839 CNV Loss 21882294

Relevant External Links for RRP36 Gene

HapMap Linkage Disequilibrium report
RRP36

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RRP36 Gene

Disorders for RRP36 Gene

No disorders were found for RRP36 Gene.

No data available for UniProtKB/Swiss-Prot for RRP36 Gene

Publications for RRP36 Gene

  1. Evolutionarily conserved function of RRP36 in early cleavages of the pre-rRNA and production of the 40S ribosomal subunit. (PMID: 20038530) Gerus M. … Henras A.K. (Mol. Cell. Biol. 2010) 2 3 4
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Complex humoral immune response against a benign tumor: frequent antibody response against specific antigens as diagnostic targets. (PMID: 15983380) Comtesse N. … Meese E. (Proc. Natl. Acad. Sci. U.S.A. 2005) 3 4
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4

Products for RRP36 Gene

Sources for RRP36 Gene

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