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RRP1B Gene

protein-coding   GIFtS: 53
GCID: GC21P045079

Ribosomal RNA Processing 1B

(Previous names: KIAA0179, ribosomal RNA processing 1 homolog B (S. cerevisiae))
(Previous symbol: KIAA0179)
  Search for RRP1B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal RNA Processing 1B1 2     Nnp12
KIAA01791 2 3 5     RRP12
RRP1-Like Protein B2 3     Ribosomal RNA Processing 1 Homolog B2
NNP1L2 5     Ribosomal RNA Processing Protein 1 Homolog B2
Ribosomal RNA Processing 1 Homolog B (S. Cerevisiae)1     

External Ids:    HGNC: 238181   Entrez Gene: 230762   Ensembl: ENSG000001602087   OMIM: 6106545   UniProtKB: Q146843   

Export aliases for RRP1B gene to outside databases

Previous GC identifers: GC21P043904 GC21P030447


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RRP1B Gene:
RRP1B (ribosomal RNA processing 1B) is a protein-coding gene. An important paralog of this gene is RRP1.

Gene Wiki entry for RRP1B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000021.8  NC_018932.2  NT_011512.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the RRP1B gene promoter:
         c-Fos   AP-1   Brachyury   Bach2   AP-4   Nkx5-1   HEN1   c-Jun   ATF   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRRP1B promoter sequence
   Search Chromatin IP Primers for RRP1B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RRP1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.3   Ensembl cytogenetic band:  21q22.3   HGNC cytogenetic band: 21q22.3

RRP1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RRP1B gene location

GeneLoc information about chromosome 21         GeneLoc Exon Structure

GeneLoc location for GC21P045079:  view genomic region     (about GC identifiers)

Start:
45,079,429 bp from pter      End:
45,115,960 bp from pter
Size:
36,532 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RRP1B_HUMAN, Q14684 (See protein sequence)
Recommended Name: Ribosomal RNA processing protein 1 homolog B  
Size: 758 amino acids; 84428 Da
Sequence caution: Sequence=BAA11496.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q8TBZ4
Alternative splicing: 2 isoforms:  Q14684-1   Q14684-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RRP1B: NX_Q14684

Explore proteomics data for RRP1B at MOPED

Post-translational modifications: 

  • Citrullinated by PADI4 (By similarity)1
  • Ubiquitination2 at Lys652
  • Modification sites at PhosphoSitePlus

  • See RRP1B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055871.1  
    ENSEMBL proteins: 
     ENSP00000339145  

    RRP1B Human Recombinant Protein Products:

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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for RRP1B

     
    Search eBioscience for Proteins for RRP1B 

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    LSBio Antibodies in human, mouse, rat for RRP1B

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    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for RRP1B
    Cloud-Clone Corp. CLIAs for RRP1B
    Search eBioscience for ELISAs for RRP1B 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR010301 Nop52

    Graphical View of Domain Structure for InterPro Entry Q14684

    ProtoNet protein and cluster: Q14684

    1 Blocks protein domain: IPB010301 Nucleolar

    UniProtKB/Swiss-Prot: RRP1B_HUMAN, Q14684
    Similarity: Belongs to the RRP1 family


    Find genes that share domains with RRP1B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with RRP1B           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for RRP1B:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RRP1B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RRP1B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RRP1B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RRP1B

    miRNA
    Products:
        
    miRTarBase miRNAs that target RRP1B:
    hsa-mir-484 (MIRT042232), hsa-mir-505-3p (MIRT041010), hsa-mir-196b-5p (MIRT042696), hsa-mir-615-3p (MIRT040297), hsa-mir-34a-5p (MIRT025330), hsa-mir-10a-5p (MIRT047655), hsa-mir-1296-5p (MIRT036131), hsa-mir-455-3p (MIRT037837), hsa-mir-125a-5p (MIRT045704), hsa-let-7b-5p (MIRT005231), hsa-mir-98-5p (MIRT027588), hsa-mir-331-3p (MIRT043565), hsa-mir-186-5p (MIRT045276), hsa-mir-940 (MIRT036605)

    Block miRNA regulation of human, mouse, rat RRP1B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RRP1B (see all 44):
    hsa-miR-4328 hsa-let-7d hsa-let-7a-2* hsa-miR-218 hsa-miR-519a hsa-let-7g hsa-let-7a hsa-miR-4274
    SwitchGear 3'UTR luciferase reporter plasmidRRP1B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RRP1B
    Predesigned siRNA for gene silencing in human, mouse, rat RRP1B

    Gene Editing
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RRP1B (NM_015056)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RRP1B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RRP1B

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for RRP1B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RRP1B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RRP1B_HUMAN, Q14684: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus5
    golgi apparatus1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000791euchromatin IEA--
    GO:0000792heterochromatin IEA--
    GO:0005634nucleus IDA16780588
    GO:0005730nucleolus IDA--
    GO:0005829cytosol IDA16780588

    Find genes that share ontologies with RRP1B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RRP1B
    Interactions:

        Search GeneGlobe Interaction Network for RRP1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RRP1B (Q146841, 3 ENSP000003391454) via UniProtKB, MINT, STRING, and/or I2D (see all 204)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LSM1O151161, 3, ENSP000003105964EBI-372051,EBI-347619 I2D: score=2 STRING: ENSP00000310596
    C7orf55-LUC7L2Q9Y3833, ENSP000003470054I2D: score=1 STRING: ENSP00000347005
    ALYREFQ86V813, ENSP000003318174I2D: score=1 STRING: ENSP00000331817
    APOA1P026473, ENSP000002368504I2D: score=1 STRING: ENSP00000236850
    DDX21Q9NR303, ENSP000003461204I2D: score=1 STRING: ENSP00000346120
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364rRNA processing IEA--
    GO:0010923negative regulation of phosphatase activity IDA19389623

    Find genes that share ontologies with RRP1B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RRP1B



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RRP1B gene: 
    NM_015056.2  

    Unigene Cluster for RRP1B:

    Ribosomal RNA processing 1 homolog B (S. cerevisiae)
    Hs.565725  [show with all ESTs]
    Unigene Representative Sequence: NM_015056
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000340648(uc002zdk.3) ENST00000470886(uc002zdl.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RRP1B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RRP1B (see all 44):
    hsa-miR-4328 hsa-let-7d hsa-let-7a-2* hsa-miR-218 hsa-miR-519a hsa-let-7g hsa-let-7a hsa-miR-4274
    SwitchGear 3'UTR luciferase reporter plasmidRRP1B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RRP1B
    Predesigned siRNA for gene silencing in human, mouse, rat RRP1B
    Clone
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    OriGene clones in human, mouse for RRP1B (see all 7)
    OriGene ORF clones in mouse, rat for RRP1B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RRP1B (NM_015056)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RRP1B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RRP1B
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for RRP1B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RRP1B
      QuantiTect SYBR Green Assays in human, mouse, rat RRP1B
      QuantiFast Probe-based Assays in human, mouse, rat RRP1B

    Additional mRNA sequence: 

    AK056263.1 BC014005.2 BC028386.2 D80001.1 

    16 DOTS entries:

    DT.100787145  DT.441385  DT.450248  DT.101980843  DT.99939879  DT.114909  DT.95169126  DT.97760082 
    DT.97846476  DT.100761039  DT.100041826  DT.40113192  DT.86842257  DT.91922594  DT.95102933  DT.95142154 

    Selected AceView cDNA sequences (see all 169):

    CR601179 AK124620 CR605276 AW150763 BM703697 AU119299 AI199682 AL043347 
    AK056263 AI472169 BE732744 AW051907 CD653125 BX374154 AI275557 BX479134 
    BE221756 BM715959 AA740730 BQ428241 BM451176 AA765528 BU156611 BX362594 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RRP1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RRP1B Expression
    About this image


    RRP1B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
     
     Bone (Muscoskeletal System)
             Bone Marrow
    RRP1B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RRP1B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.565725
        Custom PCR Arrays for RRP1B
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for RRP1B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RRP1B
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    QuantiFast Probe-based Assays in human, mouse, rat RRP1B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RRP1B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RRP1B gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rrp1b1 , 5 ribosomal RNA processing 1 homolog B (S. cerevisiae)1, 5 74.65(n)1
    65.32(a)1
      17 (17.34 cM)5
    724621  NM_028244.21  NP_082520.21 
     320361005 
    chicken
    (Gallus gallus)
    Aves RRP1B1 ribosomal RNA processing 1 homolog B (S. cerevisiae) 59.26(n)
    50.34(a)
      425237  NM_001031334.1  NP_001026505.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    43(a)
    1 → many
    3(136735017-136765865)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC537432 hypothetical protein MGC53743 71.43(n)    BC047979.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.163142 Danio rerio, Similar to DNA segment on chromosome 21 more 77.14(n)    BC045402.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nnp-16
    Nnp-1
    19(a)
    1 → many
    2L(13363300-13366188)
    worm
    (Caenorhabditis elegans)
    Secernentea C47E12.76
    Protein C47E12.7 (C47E12.7) mRNA, complete cds
    24(a)
    1 → many
    IV(9980724-9982276) WBGene00008151
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RRP1(YDR087C)4 Essential evolutionarily conserved nucleolar protein more   --   4(618306-617470) 851660  NP_010372.1 


    ENSEMBL Gene Tree for RRP1B (if available)
    TreeFam Gene Tree for RRP1B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RRP1B gene
    RRP12  
    1 SIMAP similar gene for RRP1B using alignment to 2 protein entries:     RRP1B_HUMAN (see all proteins):
    RRP1

    Find genes that share paralogs with RRP1B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RRP1B (see all 831)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 21 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1467192671,2
    --45081380(+) GCCCAC/TATCCA 1 -- int10--------
    rs22825271,2
    C,F,A,H--45081426(+) GATGAA/CATAAA 1 -- int121Minor allele frequency- C:0.40NS EA NA WA CSA 2347
    rs1403585761,2
    C--45081462(+) TCACCA/GAAACT 1 -- int10--------
    rs1932914741,2
    --45081473(+) TCTGCG/TCCCGC 1 -- int10--------
    rs1842560991,2
    --45081477(+) CGCCCA/GCATAT 1 -- int10--------
    rs1480660641,2
    C--45081703(+) GGTGTA/GCAGCA 1 -- int10--------
    rs622269361,2
    C,F--45081818(+) GCCTCG/ACCTAG 1 -- int12Minor allele frequency- A:0.12NA WA 120
    rs765191481,2
    C,F--45081846(+) CCAGGG/TTTCTA 1 -- int11Minor allele frequency- T:0.11WA 118
    rs119118651,2
    C,F,H--45081922(+) CTTCTC/TCCGAA 1 -- int1 trp33Minor allele frequency- T:0.36NA WA 122
    rs1879739951,2
    --45081976(+) ACATGC/GAACCG 1 -- int10--------

    HapMap Linkage Disequilibrium report for RRP1B (45079429 - 45115960 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for RRP1B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2723615CNV Deletion23290073
    esv2723614CNV Deletion23290073
    esv999311CNV Deletion20482838
    nsv913874CNV Loss21882294
    nsv834106CNV Loss17160897
    nsv913873CNV Loss21882294

    Human Gene Mutation Database (HGMD): RRP1B
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RRP1B
    DNA2.0 Custom Variant and Variant Library Synthesis for RRP1B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610654    OMIM disorders: --


    Find genes that share disorders with RRP1B           About GenesLikeMe

    Genetic Association Database (GAD): RRP1B
    Human Genome Epidemiology (HuGE) Navigator: RRP1B (3 documents)

    Export disorders for RRP1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RRP1B gene, integrated from 10 sources (see all 50):
    (articles sorted by number of sources associating them with RRP1B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Distinct inherited metastasis susceptibility exists for different breast cancer subtypes: a prognosis study. (PubMed id 19825179)1, 4 Hsieh S.M....Hunter K.W. (Breast Cancer Res. 2009)
    3. Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis. (PubMed id 18081427)1, 4 Crawford N.P....Hunter K.W. (PLoS Genet. 2007)
    4. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    8. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8724849)1, 2 Nagase T.... Nomura N. (DNA Res. 1996)
    9. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    10. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 23076 HGNC: 23818 AceView: KIAA0179 Ensembl:ENSG00000160208 euGenes: HUgn23076
    ECgene: RRP1B H-InvDB: RRP1B

    (According to HUGE)
    About This Section

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    HUGE: KIAA0179

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RRP1B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for RRP1B gene:
    Search GeneIP for patents involving RRP1B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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