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Aliases for RRP15 Gene

Aliases for RRP15 Gene

  • Ribosomal RNA Processing 15 Homolog (S. Cerevisiae) 2 3
  • KIAA0507 2 3 4
  • Ribosomal RNA-Processing Protein 15 3 4
  • RRP15-Like Protein 3
  • CGI-115 3

External Ids for RRP15 Gene

Previous HGNC Symbols for RRP15 Gene

  • KIAA0507

Previous GeneCards Identifiers for RRP15 Gene

  • GC01P216526
  • GC01P218458
  • GC01P189126

Summaries for RRP15 Gene

Entrez Gene Summary for RRP15 Gene

  • This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit. [provided by RefSeq, Jul 2008]

GeneCards Summary for RRP15 Gene

RRP15 (Ribosomal RNA Processing 15 Homolog (S. Cerevisiae)) is a Protein Coding gene.

Gene Wiki entry for RRP15 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RRP15 Gene

Genomics for RRP15 Gene

Regulatory Elements for RRP15 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for RRP15 Gene

218,285,287 bp from pter
218,337,983 bp from pter
52,697 bases
Plus strand

Genomic View for RRP15 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RRP15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RRP15 Gene

Proteins for RRP15 Gene

  • Protein details for RRP15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RRP15-like protein
    Protein Accession:
    Secondary Accessions:

    Protein attributes for RRP15 Gene

    282 amino acids
    Molecular mass:
    31484 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAD34110.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH20641.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for RRP15 Gene

Proteomics data for RRP15 Gene at MOPED

Post-translational modifications for RRP15 Gene

Other Protein References for RRP15 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for RRP15 Gene

Domains for RRP15 Gene

Protein Domains for RRP15 Gene


Suggested Antigen Peptide Sequences for RRP15 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the RRP15 family.
  • Belongs to the RRP15 family.
genes like me logo Genes that share domains with RRP15: view

No data available for Gene Families for RRP15 Gene

Function for RRP15 Gene

Animal Model Products

miRNA for RRP15 Gene

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RRP15

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for RRP15 Gene

Localization for RRP15 Gene

Subcellular locations from

Jensen Localization Image for RRP15 Gene COMPARTMENTS Subcellular localization image for RRP15 gene
Compartment Confidence
mitochondrion 4
nucleus 4
cytoskeleton 1
cytosol 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for RRP15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
GO:0005739 mitochondrion IDA --
genes like me logo Genes that share ontologies with RRP15: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RRP15 Gene

Pathways for RRP15 Gene

SuperPathways for RRP15 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RRP15 Gene


No data available for Pathways by source for RRP15 Gene

Transcripts for RRP15 Gene

mRNA/cDNA for RRP15 Gene

Unigene Clusters for RRP15 Gene

Ribosomal RNA processing 15 homolog (S. cerevisiae):
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RRP15

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RRP15 Gene

No ASD Table

Relevant External Links for RRP15 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RRP15 Gene

mRNA expression in normal human tissues for RRP15 Gene

Protein differential expression in normal tissues for RRP15 Gene

This gene is overexpressed in Lung (34.8) and Adrenal (7.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RRP15 Gene

SOURCE GeneReport for Unigene cluster for RRP15 Gene Hs.660109

genes like me logo Genes that share expressions with RRP15: view

Expression partners for RRP15 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RRP15 Gene

Orthologs for RRP15 Gene

This gene was present in the common ancestor of animals.

Orthologs for RRP15 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RRP15 35
  • 82.51 (n)
  • 75.89 (a)
-- 36
  • 68 (a)
RRP15 36
  • 74 (a)
(Canis familiaris)
Mammalia RRP15 35
  • 83.51 (n)
  • 77.94 (a)
RRP15 36
  • 76 (a)
(Mus musculus)
Mammalia Rrp15 35
  • 77.45 (n)
  • 75.64 (a)
Rrp15 16
Rrp15 36
  • 73 (a)
(Pan troglodytes)
Mammalia RRP15 35
  • 99.29 (n)
  • 98.23 (a)
RRP15 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Rrp15 35
  • 76.24 (n)
  • 74.91 (a)
(Monodelphis domestica)
Mammalia RRP15 36
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia RRP15 36
  • 59 (a)
(Gallus gallus)
Aves RRP15 35
  • 70.93 (n)
  • 65.2 (a)
RRP15 36
  • 60 (a)
(Anolis carolinensis)
Reptilia RRP15 36
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rrp15 35
  • 66 (n)
  • 67.16 (a)
Str.6662 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.18622 35
(Danio rerio)
Actinopterygii rrp15 35
  • 63.78 (n)
  • 61.06 (a)
wufa20e10 35
rrp15 36
  • 53 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13265 35
fruit fly
(Drosophila melanogaster)
Insecta CG3817 36
  • 26 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 39 (a)
Species with no ortholog for RRP15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RRP15 Gene

Gene Tree for RRP15 (if available)
Gene Tree for RRP15 (if available)

Paralogs for RRP15 Gene

No data available for Paralogs for RRP15 Gene

Variants for RRP15 Gene

Sequence variations from dbSNP and Humsavar for RRP15 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs12063438 -- 218,292,422(+) GCACA(C/G)AAATG intron-variant
rs12060734 -- 218,336,110(+) ACTTA(C/T)ATCTA utr-variant-3-prime
rs11805823 -- 218,284,961(+) AGGAC(A/G)CTAAA upstream-variant-2KB
rs11802635 -- 218,295,620(+) CTAGC(A/G)GATAA intron-variant
rs11800974 -- 218,333,937(+) GAACT(A/G)TGGAA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for RRP15 Gene

Variant ID Type Subtype PubMed ID
nsv873192 CNV Gain 21882294
nsv4598 CNV Loss 18451855

Relevant External Links for RRP15 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RRP15 Gene

Disorders for RRP15 Gene

No disorders were found for RRP15 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for RRP15 Gene

Publications for RRP15 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 3 4
  3. Rrp15p, a novel component of pre-ribosomal particles required for 60S ribosome subunit maturation. (PMID: 15769876) De Marchis M.L. … Fatica A. (RNA 2005) 2 3
  4. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PMID: 9455484) Seki N. … Ohara O. (DNA Res. 1997) 3
  5. Directed proteomic analysis of the human nucleolus. (PMID: 11790298) Andersen J.S. … Lamond A.I. (Curr. Biol. 2002) 3

Products for RRP15 Gene

Sources for RRP15 Gene

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