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Aliases for RRP15 Gene

Aliases for RRP15 Gene

  • Ribosomal RNA Processing 15 Homolog 2 3 5
  • KIAA0507 2 3 4
  • Ribosomal RNA-Processing Protein 15 3 4
  • Ribosomal RNA Processing 15 Homolog (S. Cerevisiae) 2
  • CGI-115 3

External Ids for RRP15 Gene

Previous HGNC Symbols for RRP15 Gene

  • KIAA0507

Previous GeneCards Identifiers for RRP15 Gene

  • GC01P216526
  • GC01P218458
  • GC01P189126

Summaries for RRP15 Gene

Entrez Gene Summary for RRP15 Gene

  • This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit. [provided by RefSeq, Jul 2008]

GeneCards Summary for RRP15 Gene

RRP15 (Ribosomal RNA Processing 15 Homolog) is a Protein Coding gene.

Gene Wiki entry for RRP15 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RRP15 Gene

Genomics for RRP15 Gene

Regulatory Elements for RRP15 Gene

Enhancers for RRP15 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RRP15 on UCSC Golden Path with GeneCards custom track

Promoters for RRP15 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RRP15 on UCSC Golden Path with GeneCards custom track

Genomic Location for RRP15 Gene

218,285,285 bp from pter
218,337,983 bp from pter
52,699 bases
Plus strand

Genomic View for RRP15 Gene

Genes around RRP15 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RRP15 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RRP15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RRP15 Gene

Proteins for RRP15 Gene

  • Protein details for RRP15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RRP15-like protein
    Protein Accession:

    Protein attributes for RRP15 Gene

    282 amino acids
    Molecular mass:
    31484 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAD34110.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH20641.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for RRP15 Gene

Proteomics data for RRP15 Gene at MOPED

Post-translational modifications for RRP15 Gene

Other Protein References for RRP15 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RRP15 Gene

Domains & Families for RRP15 Gene

Protein Domains for RRP15 Gene


Suggested Antigen Peptide Sequences for RRP15 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the RRP15 family.
  • Belongs to the RRP15 family.
genes like me logo Genes that share domains with RRP15: view

No data available for Gene Families for RRP15 Gene

Function for RRP15 Gene

Phenotypes for RRP15 Gene

genes like me logo Genes that share phenotypes with RRP15: view

Animal Model Products

miRNA for RRP15 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RRP15 Gene

Localization for RRP15 Gene

Subcellular locations from

Jensen Localization Image for RRP15 Gene COMPARTMENTS Subcellular localization image for RRP15 gene
Compartment Confidence
mitochondrion 5
nucleus 5
cytoskeleton 1
cytosol 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for RRP15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IDA --
GO:0005739 mitochondrion IDA --
genes like me logo Genes that share ontologies with RRP15: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RRP15 Gene

Pathways & Interactions for RRP15 Gene

SuperPathways for RRP15 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RRP15 Gene


No data available for Pathways by source and SIGNOR curated interactions for RRP15 Gene

Drugs & Compounds for RRP15 Gene

No Compound Related Data Available

Transcripts for RRP15 Gene

mRNA/cDNA for RRP15 Gene

Unigene Clusters for RRP15 Gene

Ribosomal RNA processing 15 homolog (S. cerevisiae):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RRP15 Gene

No ASD Table

Relevant External Links for RRP15 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RRP15 Gene

mRNA expression in normal human tissues for RRP15 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for RRP15 Gene

This gene is overexpressed in Lung (34.8) and Adrenal (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for RRP15 Gene

SOURCE GeneReport for Unigene cluster for RRP15 Gene Hs.660109

genes like me logo Genes that share expression patterns with RRP15: view

Protein tissue co-expression partners for RRP15 Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RRP15 Gene

Orthologs for RRP15 Gene

This gene was present in the common ancestor of animals.

Orthologs for RRP15 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RRP15 35
  • 82.51 (n)
  • 75.89 (a)
-- 36
  • 68 (a)
RRP15 36
  • 74 (a)
(Canis familiaris)
Mammalia RRP15 35
  • 83.51 (n)
  • 77.94 (a)
RRP15 36
  • 76 (a)
(Mus musculus)
Mammalia Rrp15 35
  • 77.45 (n)
  • 75.64 (a)
Rrp15 16
Rrp15 36
  • 73 (a)
(Pan troglodytes)
Mammalia RRP15 35
  • 99.29 (n)
  • 98.23 (a)
RRP15 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Rrp15 35
  • 76.24 (n)
  • 74.91 (a)
(Monodelphis domestica)
Mammalia RRP15 36
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia RRP15 36
  • 59 (a)
(Gallus gallus)
Aves RRP15 35
  • 70.93 (n)
  • 65.2 (a)
RRP15 36
  • 60 (a)
(Anolis carolinensis)
Reptilia RRP15 36
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rrp15 35
  • 66 (n)
  • 67.16 (a)
Str.6662 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.18622 35
(Danio rerio)
Actinopterygii rrp15 35
  • 63.78 (n)
  • 61.06 (a)
wufa20e10 35
rrp15 36
  • 53 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13265 35
fruit fly
(Drosophila melanogaster)
Insecta CG3817 36
  • 26 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 39 (a)
Species with no ortholog for RRP15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RRP15 Gene

Gene Tree for RRP15 (if available)
Gene Tree for RRP15 (if available)

Paralogs for RRP15 Gene

No data available for Paralogs for RRP15 Gene

Variants for RRP15 Gene

Sequence variations from dbSNP and Humsavar for RRP15 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs11118075 - 218,305,069(+) GTAAA(C/G)CCAGA reference, missense
rs3737978 - 218,307,616(-) TTGGT(C/T)TCTTC reference, missense
rs34358288 - 218,285,411(-) CCGAC(A/G)CTACG reference, missense
rs946213 -- 218,285,209(+) AACTC(C/T)GGGCT upstream-variant-2KB
rs952817 -- 218,337,699(+) TGAGA(A/C/G/T)AAATG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for RRP15 Gene

Variant ID Type Subtype PubMed ID
nsv873192 CNV Gain 21882294
nsv4598 CNV Loss 18451855

Variation tolerance for RRP15 Gene

Residual Variation Intolerance Score: 76.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.77; 66.68% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for RRP15 Gene

Disorders for RRP15 Gene

Relevant External Links for RRP15

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RRP15 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RRP15 Gene

Publications for RRP15 Gene

  1. Rrp15p, a novel component of pre-ribosomal particles required for 60S ribosome subunit maturation. (PMID: 15769876) De Marchis M.L. … Fatica A. (RNA 2005) 2 3 67
  2. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  4. Identifying biological pathways that underlie primordial short stature using network analysis. (PMID: 24711643) Hanson D. … Clayton P.E. (J. Mol. Endocrinol. 2014) 3
  5. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini A.A. … Barker J.N. (Nat Commun 2014) 3

Products for RRP15 Gene

Sources for RRP15 Gene