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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RRP12 Gene

protein-coding GIFtS: 51
GCID: GC10M099107

ribosomal RNA processing 12 homolog (S. cerevisiae)

(Previous name: KIAA0690 )
(Previous symbol: KIAA0690)

Explore 1 disease affiliated with
RRP12 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ribosomal RNA Processing 12 Homolog (S. Cerevisiae)¹ ²
KIAA0690¹ ² ³
RRP12-Like Protein²

External Ids:	HGNC: 29100¹	Entrez Gene: 23223²	Ensembl: ENSG00000052749⁷	UniProtKB: Q5JTH9³

Export aliases for RRP12 gene to outside databases

Previous GC identifer: GC10M092741

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Gene Wiki entry for RRP12

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_030059.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RRP12 gene promoter:
COUP-TF1 COUP HNF-4alpha2 AP-4 NF-kappaB HNF-4alpha1 IRF-2 COUP-TF NF-kappaB2 NF-kappaB1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RRP12 promoter sequence

Search SABiosciences Chromatin IP Primers for RRP12

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RRP12

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.1 Ensembl cytogenetic band: 10q24.1 HGNC cytogenetic band: 10q24.2

RRP12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RRP12 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M099107: view genomic region (about GC identifiers)

Start:	99,116,115 bp from pter	End:	99,161,127 bp from pter
Size:	45,013 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RRP12_HUMAN, Q5JTH9 (See protein sequence)

Recommended Name: RRP12-like protein

Size: 1297 amino acids; 143702 Da

Subcellular location: Nucleus, nucleolus. Nucleus membrane; Single-pass membrane protein (Potential)

Sequence caution: Sequence=BAA31665.1; Type=Erroneous initiation;

Secondary accessions: B4DK00 E9PCK7 Q5JTH8 Q69YK4 Q96E87 Q9BUH3 Q9Y4C7

Alternative splicing: 3 isoforms: Q5JTH9-1 Q5JTH9-2 Q5JTH9-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RRP12: NX_Q5JTH9

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q5JTH9

RRP12 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001138586.1 NP_055994.2

ENSEMBL proteins:

ENSP00000360031 ENSP00000324315 ENSP00000414863 ENSP00000446184

Human Recombinant Protein Products:

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	Novus Biologicals RRP12 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for RRP12

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005730	nucleolus	IEA	--
GO:0016021	integral to membrane	IEA	--
GO:0031965	nuclear membrane	IEA	--

RRP12 for ontologies About GeneDecksing

RRP12 Antibody Products:

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	Novus Biologicals RRP12 Antibodies
	Search for Antibodies for RRP12 at Abcam
	Uscn Antibodies for RRP12
	ThermoFisher Antibodies for RRP12

Assay Products for RRP12:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for RRP12
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for RRP12

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RRP12 for domains About GeneDecksing

3 InterPro domains/families:

IPR011989 ARM-like

IPR016024 ARM-type_fold

IPR012978 Uncharacterised_NUC173

Graphical View of Domain Structure for InterPro Entry Q5JTH9

ProtoNet protein and cluster: Q5JTH9

2 Blocks protein families:

IPB000357 HEAT repeat

IPB012978 Protein of unknown function

UniProtKB/Swiss-Prot: RRP12_HUMAN, Q5JTH9

Similarity: Belongs to the RRP12 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone (see all 2): RRP12 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RRP12
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate RRP12:
		hsa-miR-3155 hsa-miR-3155b hsa-miR-484
		SwitchGear 3'UTR luciferase reporter plasmid: RRP12 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RRP12 (see all 4) OriGene shRNA RFP: RRP12 OriGene siRNA: RRP12
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RRP12

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for RRP12

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RRP12 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RRP12 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): RRP12 (NM_015179)
		Browse Sino Biological Human cDNA Clones
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RRP12

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for RRP12
		Search LifeMap BioReagents cell lines for RRP12

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RRP12

3 GenomeRNAi human phenotypes for RRP12:

Decreased viability of wild-ty

Increased circadian period len

Nucleolar pre-40S maturation d

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RRP12

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/156 Interacting proteins for RRP12 (Q5JTH9^{1, 2, 3} ENSP00000360031⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 156)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MAP3K14	Q99558²^,³	MINT-48842 I2D: score=2
DDX56	Q9NY93¹^,³, ENSP00000258772⁴	EBI-310743,EBI-372376 I2D: score=5 STRING: ENSP00000258772
BYSL	Q13895³, ENSP00000230340⁴	I2D: score=4 STRING: ENSP00000230340
RIOK2	Q9BVS4³, ENSP00000283109⁴	I2D: score=4 STRING: ENSP00000283109
TSR1	Q2NL82³, ENSP00000301364⁴	I2D: score=4 STRING: ENSP00000301364

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RRP12
Search CenterWatch for drugs/clinical trials and news about RRP12

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RRP12 gene (2 alternative transcripts):

NM_001145114.1 NM_015179.3

Unigene Cluster for RRP12:

Ribosomal RNA processing 12 homolog (S. cerevisiae)

Hs.434251 [show with all ESTs]

Unigene Representative Sequence: NM_015179

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000491313(uc001kne.3) ENST00000479481(uc009xvl.3) ENST00000370992(uc009xvm.3 uc001knf.3)

ENST00000315563 ENST00000465394 ENST00000487612 ENST00000490815 ENST00000479317

ENST00000414986(uc010qou.2 uc009xvn.3) ENST00000536831

miRNA Products:		OriGene 3'-UTR Clone (see all 2): RRP12 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RRP12
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate RRP12:
		hsa-miR-3155 hsa-miR-3155b hsa-miR-484
		SwitchGear 3'UTR luciferase reporter plasmid: RRP12 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RRP12 (see all 4) OriGene shRNA RFP: RRP12 OriGene siRNA: RRP12
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RRP12

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RRP12 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RRP12 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): RRP12 (NM_015179)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RRP12
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RRP12

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RRP12 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RRP12
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RRP12
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RRP12

Additional cDNA sequence:

AB014590.1 AK000238.1 AK021460.1 AK022496.1 AK056614.1 AK131283.1 AK296315.1 AL832924.1

BC002621.2 BC012745.2

17 DOTS entries:

DT.412314 DT.100786125 DT.121278595 DT.101973641 DT.121278757 DT.92033156 DT.121278745 DT.92428900

DT.121278607 DT.97782200 DT.95094901 DT.95207694 DT.121626954 DT.91654613 DT.95094905 DT.121278606

DT.91985246

24/220 AceView cDNA sequences (see all 220):

BQ642392 BF109332 C01502 NM_015179 AB014590 BU623443 BM831458 AI143242

BM561277 BQ683355 BU632608 BU839396 BE894395 AI052651 AU117088 BM726231

AL832924 AL043253 BQ061752 BU838193 BM970164 BU626086 AI678987 CA426412

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for RRP12 (see all 9) About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4a	·	4b	^	5a	·	5b	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13a	·	13b	^	14a	·	14b	·	14c	^	15a	·	15b	^	16	^	17a	·	17b	^
SP1:
SP2:
SP3:							-
SP4:
SP5:

ExUns:	18	^	19	^	20a	·	20b	^	21a	·	21b
SP1:
SP2:
SP3:
SP4:					-
SP5:

ECgene alternative splicing isoforms for RRP12

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RRP12 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCACCAGAA

About this image
See RRP12 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RRP12

SOURCE GeneReport for Unigene cluster: Hs.434251

UniProtKB/Swiss-Prot: RRP12_HUMAN, Q5JTH9

Tissue specificity: Weakly expressed. Expressed at intermediate level in testis and ovary

SABiosciences Custom PCR Arrays for RRP12

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RRP12 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RRP12
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RRP12
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RRP12

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RRP12

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for RRP12 gene from 10/31 species (see all 31) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Rrp12^{1 , 5}	ribosomal RNA processing 12 homolog (S. cerevisiae) less^{1, 5}	87.28(n)¹ 90.94(a)¹		19 (35.36 cM)⁵ 107094¹ NM_199447.2¹ NP_955518.1¹ 41862852⁵
chicken (Gallus gallus)	Aves	RRP12¹	ribosomal RNA processing 12 homolog (S. cerevisiae) less	73.44(n) 71.61(a)		423845 NM_001012908.1 NP_001012926.1
lizard (Anolis carolinensis)	Reptilia	RRP12⁶	--	66(a)	1 ↔ 1	GL343810.1(105815-133195)
African clawed frog (Xenopus laevis)	Amphibia	CF285805.1²	--	75.48(n)		CF285805.1
zebrafish (Danio rerio)	Actinopterygii	rrp12¹	ribosomal RNA processing 12 homolog (S. cerevisiae) less	63.9(n) 62.18(a)		563195 NM_001030276.1 NP_001025447.1
fruit fly (Drosophila melanogaster)	Insecta	CG2691¹	CG2691	46.43(n) 32.88(a)		32320 NM_132678.2 NP_572906.2
worm (Caenorhabditis elegans)	Secernentea	Y46E12BL.2¹	Protein Y46E12BL.2	42.51(n) 29.32(a)		266878 NM_064918.3 NP_497319.1
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	RRP12(YPL012W)⁴ RRP12¹	Protein required for export of the ribosomal subunits; associates with the RNA components of the pre-ribosomes; has a role in nuclear import in association with Pse1p; contains HEAT-repeats less⁴ Rrp12p¹	38.81(n)¹ 28.61(a)¹		16(529723-533409)⁴ 856095^{1, 4} NP_015313.1^{1, 4}
thale cress (Arabidopsis thaliana)	eudicotyledons	AT2G34357¹	NUC173 domain-containing protein	40.54(n) 28.2(a)		2745580 NM_201868.2 NP_973597.1
rice (Oryza sativa)	Liliopsida	Os02g0782100¹	hypothetical protein	41.37(n) 26.96(a)		4330930 NM_001054849.1 NP_001048314.1

ENSEMBL Gene Tree for RRP12 (if available)
TreeFam Gene Tree for RRP12 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs181580319^1,2		--	99116054(+)	`GTGAAA/TCACAT`	2	--	int¹		0	--	--	--	--
rs142774026^1,2		--	99116083(+)	`TGTCT-/GGGAAA`	2	--	int¹		0	--	--	--	--
rs78269854^1,2	F,	--	99116172(+)	`GAATCA/GATGAA`	2	--	int¹		3		WA NA EA	358
rs142473221^1,2		--	99116220(+)	`GGCAGA/TCCCTG`	2	--	int¹		0	--	--	--	--
rs185288598^1,2		--	99116313(+)	`AAAGCC/TTGTCC`	2	--	int¹		0	--	--	--	--
rs188545442^1,2		--	99116376(+)	`GAAGAC/GGTCAG`	2	--	int¹		0	--	--	--	--
rs181340263^1,2		--	99116466(+)	`AGGATA/GAGACA`	2	--	ut3¹		0	--	--	--	--
rs185894714^1,2		--	99116655(+)	`CCAGGA/CACCAG`	2	--	ut3¹		0	--	--	--	--
rs151321664^1,2	C,	--	99116801(+)	`TGGGGA/GCTGAA`	2	--	ut3¹		0	--	--	--	--
rs200257679^1,2		--	99116814(+)	`GGCCTC/TAGACT`	2	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for RRP12 (99116115 - 99161127 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for RRP12
2 CNVs: 53133 4709

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RRP12

DNA2.0 Custom Variant and Variant Library Synthesis for RRP12

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RRP12 for disorders About GeneDecksing

1 disease for RRP12: About MalaCards

alzheimer's disease

Human Genome Epidemiology (HuGE) Navigator: RRP12 (2 documents)

Export disorders for RRP12 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RRP12 gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with RRP12)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)^{1, 2, 3} Ishikawa K.... Ohara O. (1998)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)^{1, 2} Deloukas P.... Rogers J. (2004)
Functional proteomic analysis of human nucleolus. (PubMed id 12429849)^{1, 2} Scherl A.... Diaz J.-J. (2002)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)¹ Tsai Y.C....Cristea I.M. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Integrative analysis of the ubiquitin proteome isolat ed using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)¹ Lopitz-Otsoa F....Rodriguez M.S. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 23223	HGNC: 29100	AceView: KIAA0690	Ensembl:ENSG00000052749	euGenes: HUgn23223
ECgene: RRP12	H-InvDB: RRP12

(According to HUGE)
About This Section

HUGE: KIAA0690

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for RRP12	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RRP12 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for RRP12 gene:
Search GeneIP for patents involving RRP12

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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RRP12 Gene

ribosomal RNA processing 12 homolog (S. cerevisiae)

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RRP12 Gene

ribosomal RNA processing 12 homolog (S. cerevisiae)

Aliasesfor RRP12 gene

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Genomic Viewsfor RRP12 gene

Proteinsfor RRP12 gene

Protein Domains /Familiesfor RRP12 gene

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Genome Databases showing RRP12 gene

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Specialized Databases showing RRP12 gene

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Summaries
for RRP12 gene

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Protein Domains /
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for RRP12 gene

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for RRP12 gene

Pathways & Interactions
for RRP12 gene

Drugs & Compounds
for RRP12 gene

Transcripts
for RRP12 gene

Expression
for RRP12 gene

Orthologs
for RRP12 gene

Paralogs
for RRP12 gene

Genomic Variants
for RRP12 gene

Disorders / Diseases
for RRP12 gene

Publications
for RRP12 gene

Intellectual Property
for RRP12 gene

Products
for RRP12 gene