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Aliases for RRP12 Gene

Aliases for RRP12 Gene

  • Ribosomal RNA Processing 12 Homolog (S. Cerevisiae) 2 3
  • KIAA0690 2 3 4
  • RRP12-Like Protein 3
  • SFRS2IP 6
  • SRRP129 6
  • SCAF11 6
  • CASP11 6
  • SIP1 6

External Ids for RRP12 Gene

Previous HGNC Symbols for RRP12 Gene

  • KIAA0690

Previous GeneCards Identifiers for RRP12 Gene

  • GC10M099107
  • GC10M092741

Summaries for RRP12 Gene

GeneCards Summary for RRP12 Gene

RRP12 (Ribosomal RNA Processing 12 Homolog (S. Cerevisiae)) is a Protein Coding gene.

Gene Wiki entry for RRP12 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RRP12 Gene

Genomics for RRP12 Gene

Genomic Location for RRP12 Gene

97,356,358 bp from pter
97,426,076 bp from pter
69,719 bases
Minus strand

Genomic View for RRP12 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RRP12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RRP12 Gene

Proteins for RRP12 Gene

  • Protein details for RRP12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RRP12-like protein
    Protein Accession:
    Secondary Accessions:
    • B4DK00
    • E9PCK7
    • Q5JTH8
    • Q69YK4
    • Q96E87
    • Q9BUH3
    • Q9Y4C7

    Protein attributes for RRP12 Gene

    1297 amino acids
    Molecular mass:
    143702 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA31665.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for RRP12 Gene


neXtProt entry for RRP12 Gene

Proteomics data for RRP12 Gene at MOPED

Post-translational modifications for RRP12 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for RRP12 Gene

Domains for RRP12 Gene

Protein Domains for RRP12 Gene

Suggested Antigen Peptide Sequences for RRP12 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the RRP12 family.
  • Belongs to the RRP12 family.
genes like me logo Genes that share domains with RRP12: view

No data available for Gene Families for RRP12 Gene

Function for RRP12 Gene

Gene Ontology (GO) - Molecular Function for RRP12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005488 binding --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RRP12: view
genes like me logo Genes that share phenotypes with RRP12: view

Animal Model Products

miRNA for RRP12 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RRP12

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for RRP12 Gene

Localization for RRP12 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RRP12 Gene

Nucleus, nucleolus. Nucleus membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for RRP12 Gene COMPARTMENTS Subcellular localization image for RRP12 gene
Compartment Confidence
nucleus 5
mitochondrion 2
cytosol 1
endoplasmic reticulum 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for RRP12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IDA --
GO:0016021 integral component of membrane IEA --
GO:0031965 nuclear membrane IEA --
genes like me logo Genes that share ontologies with RRP12: view

Pathways for RRP12 Gene

SuperPathways for RRP12 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RRP12 Gene


No data available for Pathways by source for RRP12 Gene

Transcripts for RRP12 Gene

Unigene Clusters for RRP12 Gene

Ribosomal RNA processing 12 homolog (S. cerevisiae):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RRP12

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RRP12 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b · 14c ^ 15a · 15b ^ 16 ^ 17a · 17b ^
SP3: -
SP6: - -
SP8: -

ExUns: 18 ^ 19 ^ 20a · 20b ^ 21a · 21b
SP4: -

Relevant External Links for RRP12 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RRP12 Gene

mRNA expression in normal human tissues for RRP12 Gene

mRNA differential expression in normal tissues according to GTEx for RRP12 Gene

This gene is overexpressed in Whole Blood (4.9) and Muscle - Skeletal (4.3).

Protein differential expression in normal tissues for RRP12 Gene

This gene is overexpressed in Bone (11.8) and Peripheral blood mononuclear cells (8.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RRP12 Gene

SOURCE GeneReport for Unigene cluster for RRP12 Gene Hs.434251

mRNA Expression by UniProt/SwissProt for RRP12 Gene

Tissue specificity: Weakly expressed. Expressed at intermediate level in testis and ovary.
genes like me logo Genes that share expressions with RRP12: view

Expression partners for RRP12 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for RRP12 Gene

Orthologs for RRP12 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RRP12 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RRP12 35
  • 87.72 (n)
  • 90.32 (a)
RRP12 36
  • 92 (a)
(Canis familiaris)
Mammalia RRP12 35
  • 89.17 (n)
  • 92.05 (a)
RRP12 36
  • 92 (a)
(Mus musculus)
Mammalia Rrp12 35
  • 87.1 (n)
  • 90.48 (a)
Rrp12 16
Rrp12 36
  • 91 (a)
(Pan troglodytes)
Mammalia RRP12 35
  • 99.2 (n)
  • 99.23 (a)
RRP12 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Rrp12 35
  • 86.89 (n)
  • 89.71 (a)
(Monodelphis domestica)
Mammalia RRP12 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia RRP12 36
  • 75 (a)
(Gallus gallus)
Aves RRP12 35
  • 73.16 (n)
  • 71.37 (a)
RRP12 36
  • 71 (a)
(Anolis carolinensis)
Reptilia RRP12 36
  • 66 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rrp12 35
  • 66.56 (n)
  • 68.85 (a)
(Danio rerio)
Actinopterygii rrp12 35
  • 63.98 (n)
  • 62.33 (a)
rrp12 36
  • 61 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002961 35
  • 46.91 (n)
  • 34.08 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG2691 35
  • 46.05 (n)
  • 32.72 (a)
CG2691 36
  • 29 (a)
(Caenorhabditis elegans)
Secernentea Y46E12BL.2 35
  • 42.72 (n)
  • 29.62 (a)
Y46E12BL.2 36
  • 25 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AGL014C 35
  • 40.78 (n)
  • 27.52 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F27269g 35
  • 40.15 (n)
  • 29.13 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RRP12 35
  • 38.92 (n)
  • 28.63 (a)
RRP12 36
  • 24 (a)
RRP12 38
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G34357 35
  • 40.66 (n)
  • 28.3 (a)
(Oryza sativa)
Liliopsida Os02g0782100 35
  • 41.31 (n)
  • 28.11 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU01675 35
  • 44.98 (n)
  • 29.05 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 40 (a)
Species with no ortholog for RRP12:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RRP12 Gene

Gene Tree for RRP12 (if available)
Gene Tree for RRP12 (if available)

Paralogs for RRP12 Gene

No data available for Paralogs for RRP12 Gene

Variants for RRP12 Gene

Sequence variations from dbSNP and Humsavar for RRP12 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs3814553 -- 97,396,227(-) TACTT(C/T)GCTGC reference, synonymous-codon
rs3737194 -- 97,370,370(+) GGCAC(A/G)GAGCT intron-variant
rs2297990 -- 97,367,166(+) GAGGC(A/G)AGCCT intron-variant
rs2297989 -- 97,366,962(+) CGACC(C/T)AGATG intron-variant
rs2297988 -- 97,358,625(+) CTGCT(C/T)GCCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RRP12 Gene

Variant ID Type Subtype PubMed ID
nsv831952 CNV Loss 17160897
nsv895914 CNV Gain 21882294
dgv119n27 CNV Loss 19166990
nsv825535 CNV Gain 20364138
nsv467440 CNV Loss 19166990
esv2739884 CNV Deletion 23290073
esv2739895 CNV Deletion 23290073

Relevant External Links for RRP12 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RRP12 Gene

Disorders for RRP12 Gene

Relevant External Links for RRP12

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for RRP12 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for RRP12 Gene

Publications for RRP12 Gene

  1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9734811) Ishikawa K. … Ohara O. (DNA Res. 1998) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 48

Products for RRP12 Gene

Sources for RRP12 Gene

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