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RRP12 Gene

protein-coding   GIFtS: 55
GCID: GC10M099107

Ribosomal RNA Processing 12 Homolog (S. Cerevisiae)

(Previous name: KIAA0690)
(Previous symbol: KIAA0690)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal RNA Processing 12 Homolog (S. Cerevisiae)1 2     SCAF115
KIAA06901 2 3     SFRS2IP5
RRP12-Like Protein2     SIP15
CASP115     SRRP1295

External Ids:    HGNC: 291001   Entrez Gene: 232232   Ensembl: ENSG000000527497   OMIM: 6036685   UniProtKB: Q5JTH93   

Export aliases for RRP12 gene to outside databases

Previous GC identifer: GC10M092741


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RRP12 Gene:
RRP12 (ribosomal RNA processing 12 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with RRP12 include alzheimer's disease, and multiple myeloma.

Gene Wiki entry for RRP12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the RRP12 gene promoter:
         COUP-TF1   COUP   HNF-4alpha2   AP-4   NF-kappaB   HNF-4alpha1   IRF-2   COUP-TF   NF-kappaB2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRRP12 promoter sequence
   Search Chromatin IP Primers for RRP12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RRP12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.1   Ensembl cytogenetic band:  10q24.1   HGNC cytogenetic band: 10q24.2

RRP12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RRP12 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M099107:  view genomic region     (about GC identifiers)

Start:
99,116,115 bp from pter      End:
99,161,127 bp from pter
Size:
45,013 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RRP12_HUMAN, Q5JTH9 (See protein sequence)
Recommended Name: RRP12-like protein  
Size: 1297 amino acids; 143702 Da
Sequence caution: Sequence=BAA31665.1; Type=Erroneous initiation;
Secondary accessions: B4DK00 E9PCK7 Q5JTH8 Q69YK4 Q96E87 Q9BUH3 Q9Y4C7
Alternative splicing: 3 isoforms:  Q5JTH9-1   Q5JTH9-2   Q5JTH9-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RRP12: NX_Q5JTH9

Explore proteomics data for RRP12 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RRP12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001138586.1  NP_001271266.1  NP_055994.2  

    ENSEMBL proteins: 
     ENSP00000360031   ENSP00000324315   ENSP00000414863   ENSP00000446184  

    RRP12 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR011989 ARM-like
     IPR016024 ARM-type_fold
     IPR012978 Uncharacterised_NUC173

    Graphical View of Domain Structure for InterPro Entry Q5JTH9

    ProtoNet protein and cluster: Q5JTH9

    2 Blocks protein domains:
    IPB000357 HEAT repeat
    IPB012978 Protein of unknown function


    UniProtKB/Swiss-Prot: RRP12_HUMAN, Q5JTH9
    Similarity: Belongs to the RRP12 family


    RRP12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    RRP12 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for RRP12:
     Decreased viability of wild-ty  Increased circadian period len  Nucleolar pre-40S maturation d 

    Animal Models:
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    miRNA
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    miRTarBase miRNAs that target RRP12:
    hsa-mir-328-3p (MIRT043788), hsa-mir-24-3p (MIRT030475), hsa-mir-16-5p (MIRT031543), hsa-mir-93-3p (MIRT038758)

    Block miRNA regulation of human, mouse, rat RRP12 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate RRP12:
    hsa-miR-3155 hsa-miR-3155b hsa-miR-484
    SwitchGear 3'UTR luciferase reporter plasmidRRP12 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat RRP12

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RRP12


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RRP12_HUMAN, Q5JTH9: Nucleus, nucleolus. Nucleus membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    mitochondrion2
    cytosol1
    endoplasmic reticulum1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--
    GO:0016021integral component of membrane IEA--
    GO:0031965nuclear membrane IEA--

    RRP12 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RRP12
    Interactions:

        Search GeneGlobe Interaction Network for RRP12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RRP12 (Q5JTH91, 2, 3 ENSP000003600314) via UniProtKB, MINT, STRING, and/or I2D (see all 271)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP3K14Q995582, 3MINT-48842 I2D: score=2 
    ENSG00000204221O152133I2D: score=4 
    ENSG00000206284O152133I2D: score=4 
    ENSG00000226916O152133I2D: score=4 
    ENSG00000236222O152133I2D: score=4 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RRP12



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RRP12 gene (3 alternative transcripts): 
    NM_001145114.1  NM_001284337.1  NM_015179.3  

    Unigene Cluster for RRP12:

    Ribosomal RNA processing 12 homolog (S. cerevisiae)
    Hs.434251  [show with all ESTs]
    Unigene Representative Sequence: NM_015179
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000491313(uc001kne.3) ENST00000479481(uc009xvl.3) ENST00000370992(uc009xvm.3 uc001knf.3)
    ENST00000315563 ENST00000465394 ENST00000487612 ENST00000490815 ENST00000479317
    ENST00000414986(uc010qou.2 uc009xvn.3) ENST00000536831
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RRP12 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate RRP12:
    hsa-miR-3155 hsa-miR-3155b hsa-miR-484
    SwitchGear 3'UTR luciferase reporter plasmidRRP12 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RRP12
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    GenScript: all cDNA clones in your preferred vector (see all 2): RRP12 (NM_015179)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RRP12
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RRP12
    Primer
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    OriGene qPCR primer pairs and template standards for RRP12
    OriGene qSTAR qPCR primer pairs in human, mouse for RRP12
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RRP12
      QuantiTect SYBR Green Assays in human, mouse, rat RRP12
      QuantiFast Probe-based Assays in human, mouse, rat RRP12

    Additional mRNA sequence: 

    AB014590.1 AK000238.1 AK021460.1 AK022496.1 AK056614.1 AK131283.1 AK296315.1 AL832924.1 
    BC002621.2 BC012745.2 

    17 DOTS entries:

    DT.412314  DT.100786125  DT.121278595  DT.101973641  DT.121278757  DT.92033156  DT.121278745  DT.92428900 
    DT.121278607  DT.97782200  DT.95094901  DT.95207694  DT.121626954  DT.91654613  DT.95094905  DT.121278606 
    DT.91985246 

    Selected AceView cDNA sequences (see all 220):

    NM_015179 C01502 BQ642392 BF109332 AB014590 BU623443 BM831458 AI143242 
    BM561277 BM726231 AU117088 BU632608 BU839396 AI052651 BQ683355 BE894395 
    AL043253 AL832924 BQ061752 BU838193 BM970164 BU626086 AI678987 CA426412 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RRP12 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b · 14c ^ 15a · 15b ^ 16 ^ 17a · 17b ^
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                    -                                                                                                                                       
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 18 ^ 19 ^ 20a · 20b ^ 21a · 21b
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:              -                     
    SP5:                                    


    ECgene alternative splicing isoforms for RRP12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RRP12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCACCAGAA
    RRP12 Expression
    About this image

    RRP12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RRP12 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.434251

    UniProtKB/Swiss-Prot: RRP12_HUMAN, Q5JTH9
    Tissue specificity: Weakly expressed. Expressed at intermediate level in testis and ovary

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RRP12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RRP12 gene from Selected species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rrp121 , 5 ribosomal RNA processing 12 homolog (S. cerevisiae)1, 5 87.1(n)1
    90.48(a)1
      19 (35.36 cM)5
    1070941  NM_199447.21  NP_955518.11 
     418628525 
    chicken
    (Gallus gallus)
    Aves RRP121 ribosomal RNA processing 12 homolog (S. cerevisiae) 73.16(n)
    71.37(a)
      423845  NM_001012908.1  NP_001012926.1 
    lizard
    (Anolis carolinensis)
    Reptilia RRP126
    ribosomal RNA processing 12 homolog (S. cerevisiae...
    66(a)
    1 ↔ 1
    GL343810.1(105543-134379)
    African clawed frog
    (Xenopus laevis)
    Amphibia CF285805.12   -- 75.48(n)    CF285805.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rrp121 ribosomal RNA processing 12 homolog (S. cerevisiae) 63.98(n)
    62.33(a)
      563195  NM_001030276.2  NP_001025447.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG26911 CG2691 46.05(n)
    32.72(a)
      32320  NM_132678.2  NP_572906.2 
    worm
    (Caenorhabditis elegans)
    Secernentea Y46E12BL.21 Y46E12BL.2 42.72(n)
    29.62(a)
      266878  NM_064918.4  NP_497319.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RRP12(YPL012W)4
    RRP121
    Protein required for export of the ribosomal subunits; more4
    RRP121
    38.92(n)1
    28.63(a)1
      16(529723-533409)4
    8560951, 4  NP_015313.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G343571 AT2G34357 40.66(n)
    28.3(a)
      2745580  NM_201868.2  NP_973597.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g07821001 Os02g0782100 41.31(n)
    28.11(a)
      4330930  NM_001054849.1  NP_001048314.1 


    ENSEMBL Gene Tree for RRP12 (if available)
    TreeFam Gene Tree for RRP12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RRP12 (see all 1313)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1815803191,2
    C--99116054(+) GTGAAA/TCACAT 2 -- int10--------
    rs1427740261,2
    --99116083(+) TGTCT-/GGGAAA 2 -- int10--------
    rs782698541,2
    C,F--99116172(+) GAATCA/GATGAA 2 -- int13Minor allele frequency- G:0.07WA NA EA 358
    rs1424732211,2
    C--99116220(+) GGCAGA/TCCCTG 2 -- int10--------
    rs1852885981,2
    --99116313(+) AAAGCC/TTGTCC 2 -- int10--------
    rs1885454421,2
    C--99116376(+) GAAGAC/GGTCAG 2 -- int10--------
    rs1813402631,2
    --99116466(+) AGGATA/GAGACA 2 -- ut310--------
    rs1858947141,2
    --99116655(+) CCAGGA/CACCAG 2 -- ut310--------
    rs1513216641,2
    C--99116801(+) TGGGGA/GCTGAA 2 -- ut310--------
    rs2002576791,2
    --99116814(+) GGCCTC/TAGACT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for RRP12 (99116115 - 99161127 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for RRP12:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2739895CNV Deletion23290073
    esv2739884CNV Deletion23290073
    nsv467440CNV Loss19166990
    dgv119n27CNV Loss19166990
    nsv831952CNV Loss17160897
    nsv825535CNV Gain20364138
    nsv895914CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RRP12
    DNA2.0 Custom Variant and Variant Library Synthesis for RRP12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603668    OMIM disorders: --

    5 diseases for RRP12:    
    About MalaCards
    alzheimer's disease    multiple myeloma    myeloma    breast cancer
    malaria


    RRP12 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RRP12
    Human Genome Epidemiology (HuGE) Navigator: RRP12 (2 documents)

    Export disorders for RRP12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RRP12 gene, integrated from 10 sources (see all 40):
    (articles sorted by number of sources associating them with RRP12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (DNA Res. 1998)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    8. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    9. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    10. The functional interactome landscape of the human histone deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (Mol. Syst. Biol. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23223 HGNC: 29100 AceView: KIAA0690 Ensembl:ENSG00000052749 euGenes: HUgn23223
    ECgene: RRP12 H-InvDB: RRP12

    (According to HUGE)
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    HUGE: KIAA0690

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RRP12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RRP12 gene:
    Search GeneIP for patents involving RRP12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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