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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RRN3P2 Gene

pseudogene   GIFtS: 30
GCID: GC16P029089

RNA polymerase I transcription factor homolog (S. cerevisiae)...

  Search for RRN3P2
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
RNA Polymerase I Transcription Factor Homolog (S. Cerevisiae) Pseudogene
21 2
RNA Polymerase I Transcription Factor Homolog Pseudogene 23

External Ids:    HGNC: 376191   Entrez Gene: 6533902   Ensembl: ENSG000001034727   UniProtKB: A6NIE63   
ORGUL members:         
NONCODE:n386951 n386950 n382954 n346322 n382953    

Export aliases for RRN3P2 gene to outside databases

Previous GC identifers: GC16P028997 GC16P026953


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for RRN3P2
         Other transcription factors

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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RRN3P2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p11.2   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p11.2

RRN3P2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RRN3P2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P029089:  view genomic region     (about GC identifiers)

Start:
29,086,163 bp from pter      End:
29,128,039 bp from pter
Size:
41,877 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for RRN3P2

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RN3P2_HUMAN, A6NIE6 (See protein sequence)
Recommended Name: Putative RRN3-like protein RRN3P2  
Size: 340 amino acids; 38035 Da
Caution: Could be the product of a pseudogene

Explore the universe of human proteins at neXtProt for RRN3P2: NX_A6NIE6

RRN3P2 Protein expression data from MOPED and PaxDb: --

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RRN3P2 for domains           About GeneDecksing

1 InterPro domain/family:
 IPR007991 RNA_pol_I_trans_ini_fac_RRN3

Graphical View of Domain Structure for InterPro Entry A6NIE6

ProtoNet protein and cluster: A6NIE6

UniProtKB/Swiss-Prot: RN3P2_HUMAN, A6NIE6
Similarity: Belongs to the RRN3 family


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RRN3P2

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
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(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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About This Section

Unigene Cluster for RRN3P2:

RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2
Hs.720348  [show with all ESTs]
Unigene Representative Sequence: NR_003369
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000564580(uc002dsf.4 uc002dsg.4 uc010vdn.2) ENST00000427965
ENST00000566038 ENST00000415221(uc010vdm.1) ENST00000219758

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Additional cDNA sequence: 

AK225670.1 AK298442.1 AK301253.1 NR_003369.2 

21 DOTS entries:

DT.102841357  DT.446132  DT.120696043  DT.120691873  DT.120692454  DT.405646  DT.102841396  DT.120658548 
DT.70103418  DT.92453496  DT.120658450  DT.120696252  DT.120696844  DT.97843843  DT.102841949  DT.120658564 
DT.120658640  DT.120658978  DT.443174  DT.92453498  DT.92453504 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for RRN3P2    About this scheme

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9
SP1:                                                  -               
SP2:                    -                                             
SP3:              -     -                                             


ECgene alternative splicing isoforms for RRN3P2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RRN3P2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATATATCAA
RRN3P2 Expression
About this image
Genevestigator expression for RRN3P2

SOURCE GeneReport for Unigene cluster: Hs.720348
    SABiosciences Custom PCR Arrays for RRN3P2

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In Situ
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
  --

ENSEMBL Gene Tree for RRN3P2 (if available)
TreeFam Gene Tree for RRN3P2 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/658 NCBI SNPs in RRN3P2 are shown (see all 658    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 16 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs81821681,2
C--26954103(+) CCGGCC/TTGAGG 1 -- nc-transcript-variant0--------
rs24325131,2
C,F,H--26954249(+) TTCTGC/TGCGTC 1 -- int16Minor allele frequency- T:0.02NS NA 636
rs620353081,2
C--26954768(+) TGAAGG/CAAACC 1 -- int11Minor allele frequency- C:0.50NA 2
rs286787241,2
--26955529(+) TGTAGC/GATCTT 1 -- int10--------
rs29113581,2
H--26955532(+) aggatC/Tttaaa 1 -- int14Minor allele frequency- T:0.00NS EA 418
rs1716691,2
C,A--26956928(-) ACAAGG/AAGGGG 1 -- int1 trp31Minor allele frequency- A:0.50NA 2
rs25951811,2
C--26957193(+) cacaaC/Ttggga 1 -- int11Minor allele frequency- T:0.50NA 2
rs25417261,2
C--26957219(-) cactaG/Aatgcc 1 -- int11Minor allele frequency- A:0.50NA 2
rs2522721,2
C,F,H--26972183(-) aaaaaG/Taaatc 1 -- int112Minor allele frequency- T:0.12NS EA NA 1724
rs559579641,2
C--26972629(-) TTTGCA/GTAACT 1 -- int10--------

HapMap Linkage Disequilibrium report for RRN3P2 (29086163 - 29128039 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for RRN3P2
     2 CNVs: 5819 3999

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for RRN3P2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RRN3P2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (2004)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 653390 HGNC: 37619 Ensembl:ENSG00000103472 euGenes: HUgn653390 ECgene: RRN3P2
H-InvDB: RRN3P2

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for RRN3P2 gene:
Search GeneIP for patents involving RRN3P2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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