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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RRH Gene

protein-coding   GIFtS: 58
GCID: GC04P110749

Retinal Pigment Epithelium-Derived Rhodopsin Homolog

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Retinal Pigment Epithelium-Derived Rhodopsin Homolog1 2
peropsin1 2
Visual Pigment-Like Receptor Peropsin2

External Ids:    HGNC: 104501   Entrez Gene: 106922   Ensembl: ENSG000001802457   OMIM: 6052245   UniProtKB: O147183   

Export aliases for RRH gene to outside databases

Previous GC identifers: GC04U990073 GC04P111019 GC04P111142 GC04P111207 GC04P111106 GC04P110968 GC04P106481


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RRH Gene:
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene
belongs to the seven-exon subfamily of mammalian opsin genes that includes opsin 5 and retinal G protein coupled
receptor. (provided by RefSeq, Jul 2008)

GeneCards Summary for RRH Gene: 
RRH (retinal pigment epithelium-derived rhodopsin homolog) is a protein-coding gene. Diseases associated with RRH include stomach cancer, and alcohol dependence, and among its related super-pathways are Class A/1 (Rhodopsin-like receptors) and Signaling by GPCR. GO annotations related to this gene include photoreceptor activity and G-protein coupled receptor activity. An important paralog of this gene is OPN3.

UniProtKB/Swiss-Prot: OPSX_HUMAN, O14718
Function: May play a role in rpe physiology either by detecting light directly or by monitoring the concentration
of retinoids or other photoreceptor-derived compounds

Gene Wiki entry for RRH Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RRH gene promoter:
         CREB   Sp1   p53   ATF-2   STAT3   STAT5A   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRRH promoter sequence
   Search SABiosciences Chromatin IP Primers for RRH

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RRH


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q25   Ensembl cytogenetic band:  4q25   HGNC cytogenetic band: 4q25

RRH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RRH gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P110749:  view genomic region     (about GC identifiers)

Start:
110,749,150 bp from pter      End:
110,765,863 bp from pter
Size:
16,714 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: OPSX_HUMAN, O14718 (See protein sequence)
Recommended Name: Visual pigment-like receptor peropsin  
Size: 337 amino acids; 37423 Da
Subcellular location: Membrane; Multi-pass membrane protein (By similarity)
Secondary accessions: A1A4V2 Q7RTS4

Explore the universe of human proteins at neXtProt for RRH: NX_O14718

Explore proteomics data for RRH at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O14718

  • RRH Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RRH Protein Expression
    REFSEQ proteins: NP_006574.1  
    ENSEMBL proteins: 
     ENSP00000314992  
    Reactome Protein details: O14718
    Human Recombinant Protein Products for RRH: 
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for RRH 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral to plasma membrane TAS9275222
    GO:0016021integral to membrane ----

    RRH for ontologies           About GeneDecksing



    RRH Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for RRH 

    Assay Products for RRH: 
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RRH 
    Cloud-Clone Corp. CLIAs for RRH


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    OPN: GPCR / Class A : Opsin receptors

    4 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR002962 Peropsin
     IPR027430 Retinal_BS
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry O14718

    ProtoNet protein and cluster: O14718

    2 Blocks protein domains:
    IPB001760 Opsin
    IPB002962 Peropsin signature


    UniProtKB/Swiss-Prot: OPSX_HUMAN, O14718
    Similarity: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily


    RRH for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OPSX_HUMAN, O14718
    Function: May play a role in rpe physiology either by detecting light directly or by monitoring the concentration
    of retinoids or other photoreceptor-derived compounds

         Genatlas biochemistry entry for RRH:
    peropsin,retinol pigment epithelium-derived,rhodopsin homolog,located in the apical microvilli of RPE,putative
    regulator of RPE function or activity

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
    GO:0009881photoreceptor activity IEA--
         
    RRH for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for RRH:
     Increased circadian period len  Metaphase cells 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RRH 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RRH

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RRH 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RRH 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RRH
    1 QIAGEN miScript miRNA Assays for microRNA that regulate RRH:
    hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidRRH 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Clone
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    In Situ Assay
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RRH About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)0.71
    G alpha (i) signalling events0.46
    GPCR ligand binding0.71
    GPCRs, Class A Rhodopsin-like0.41
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.55
    GPCR downstream signaling0.90
    3Opsins
    Opsins

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for RRH
        GPCRs, Class A Rhodopsin-like

    5/7        Reactome Pathways for RRH (see all 7)
        GPCR downstream signaling
    Signal Transduction
    Signaling by GPCR
    G alpha (i) signalling events
    GPCR ligand binding



    RRH for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RRH

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for RRH (O147183 ENSP000003149924) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TGFBR1P368973, ENSP000003641334I2D: score=3 STRING: ENSP00000364133
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway TAS9275222
    GO:0007601visual perception IEA--
    GO:0007602phototransduction IEA--
    GO:0018298protein-chromophore linkage IEA--

    RRH for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RRH (OPSX)

    Search CenterWatch for drugs/clinical trials and news about RRH / OPSX

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RRH gene: 
    NM_006583.2  

    Unigene Cluster for RRH:

    Retinal pigment epithelium-derived rhodopsin homolog
    Hs.658310  [show with all ESTs]
    Unigene Representative Sequence: NM_006583
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000317735(uc003hzv.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RRH
    1 QIAGEN miScript miRNA Assays for microRNA that regulate RRH:
    hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidRRH 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene RNAi products in human, mouse, rat for RRH
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RRH
    Clone
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    OriGene clones in human, mouse for RRH (see all 7)
    OriGene ORF clones in mouse, rat for RRH
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RRH (NM_006583)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RRH
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RRH
    Sirion Biotech Customized lentivirus for stable overexpression of RRH 
                         Customized lentivirus expression plasmids for stable overexpression of RRH 
    Primer
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    OriGene qPCR primer pairs and template standards for RRH
    OriGene qSTAR qPCR primer pairs in human, mouse for RRH
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RRH
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RRH
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RRH

    Additional mRNA sequence: 

    AF012270.1 BC128120.1 BC128121.1 BC128401.1 

    3 DOTS entries:

    DT.40281681  DT.121268495  DT.121268496 

    4 AceView cDNA sequences:

    NM_006583 BM931227 AF012270 D59750 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RRH expression in normal human tissues (normalized intensities)      RRH embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTGTTTCTA
    RRH Expression
    About this image


    RRH expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Eye (Sensory Organs)
             Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Choroid Plexus (Nervous System)
             Mature Choroid Plexus Cells Choroid Plexus
     
     Brain (Nervous System)
             Mature Choroid Plexus Cells Choroid Plexus

    See RRH Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RRH

    SOURCE GeneReport for Unigene cluster: Hs.658310

    UniProtKB/Swiss-Prot: OPSX_HUMAN, O14718
    Tissue specificity: Found only in the eye, where it is localized to the retinal pigment epithelium (RPE). In the
    RPE, it is localized to the microvilli that surround the photoreceptor outer segments

        SABiosciences Expression via Pathway-Focused PCR Array including RRH: 
              G Protein Coupled Receptors 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RRH

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RRH gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rrh1 , 5 retinal pigment epithelium derived rhodopsin homolog1, 5 82.78(n)1
    80.24(a)1
      3 (59.09 cM)5
    201321  NM_009102.31  NP_033128.11 
     1298085755 
    chicken
    (Gallus gallus)
    Aves RRH1 retinal pigment epithelium-derived rhodopsin homolog 74.92(n)
    76.44(a)
      771805  NM_001079759.1  NP_001073227.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    74(a)
    71(a)
    1 ↔ many
    1 ↔ many
    AAWZ02038674(3545-10340)
    5(144365885-144373133)
    zebrafish
    (Danio rerio)
    Actinopterygii rrh1 retinal pigment epithelium-derived rhodopsin homolog 66.77(n)
    71.25(a)
      447916  NM_001004654.1  NP_001004654.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta ninaE6
    Rh66
    (see all 7)
    Rhodopsin 6
    (see all 7)
    23(a)
    21(a)
    (see all 7)
    many ↔ many
    many ↔ many
    (see all 7)
    3R(15711968-15713928)
    3R(11308880-11310421)


    ENSEMBL Gene Tree for RRH (if available)
    TreeFam Gene Tree for RRH (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RRH gene
    OPN32  RGR2  OPN1MW22  OPN42  OPN1LW2  OPN1MW2  OPN1SW2  RHO2  
    OPN52  
    9 SIMAP similar genes for RRH using alignment to 1 protein entry:     OPSX_HUMAN:
    OPN5    RHO    OPN1MW    OPN1MW2    DKFZp781I1948    OPN1LW
    OPN4    OPN3    RGR

    RRH for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/440 SNPs in RRH are shown (see all 440)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs102131041,2
    C,F--110747184(+) ttttgC/Ttcttg 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1898686691,2
    --110747278(+) CTCCCA/TAGTAG 1 -- us2k10--------
    rs779733051,2
    --110747654(+) TTAGAA/TATAAT 1 -- us2k10--------
    rs1396021511,2
    C--110747742(+) CAAATG/TCAAAA 1 -- us2k10--------
    rs1821712831,2
    --110747791(+) ACAAAC/GACTTT 1 -- us2k10--------
    rs100007621,2
    C,F,H--110747864(+) ACTGAC/TGAGAT 1 -- us2k17Minor allele frequency- T:0.02NS EA NA WA 542
    rs1875433431,2
    --110747883(+) CTAGTA/GTAGGT 1 -- us2k10--------
    rs1929648551,2
    --110747959(+) ACCTGG/TTCATC 1 -- us2k10--------
    rs1829761931,2
    C--110748194(+) AAAGAA/GTATGG 1 -- us2k10--------
    rs100257061,2
    C,F,H--110748205(+) GAAAAA/GAGGTA 1 -- us2k1 trp312Minor allele frequency- G:0.06NS EA NA CSA WA 1538

    HapMap Linkage Disequilibrium report for RRH (110749150 - 110765863 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RRH: --

    Human Gene Mutation Database (HGMD): RRH
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RRH
    DNA2.0 Custom Variant and Variant Library Synthesis for RRH

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605224    OMIM disorders: --

    6 diseases for RRH:    About MalaCards
    stomach cancer    alcohol dependence    retinitis    myopia
    retinitis pigmentosa    alcoholism

    1 disease from the University of Copenhagen DISEASES database for RRH:
    Retinitis pigmentosa

    RRH for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for RRH gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinitis pigmentosa 69.1 3 17167409 (2), 12542842 (1)

    Genetic Association Database (GAD): RRH
    Human Genome Epidemiology (HuGE) Navigator: RRH (1 document)

    Export disorders for RRH gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RRH gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with RRH)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Peropsin, a novel visual pigment-like protein located in the apical microvilli of the retinal pigment epithelium. (PubMed id 9275222)1, 2, 3, 9 Sun H.... Nathans J. (1997)
    2. In silico characterisation and chromosomal localisation of human RRH (peropsin) -- implications for opsin evolution. (PubMed id 12542842)1, 2, 9 Bellingham J.... Foster R.G. (2003)
    3. A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1, 4 Kalsi G....Riley B.P. (2010)
    4. Mutation screening of the peropsin gene, a retinal pigment epithelium specific rhodopsin homolog, in patients with retinitis pigmentosa and allied diseases. (PubMed id 17167409)1, 9 Rivolta C....Dryja T.P. (2006)
    5. Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. (PubMed id 18240029)1 Luttrell L.M. (2008)
    6. High-throughput mapping of a dynamic signaling network in mammalian cells. (PubMed id 15761153)1 Barrios-Rodiles M....Wrana J.L. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Creation of genome-wide protein expression libraries using random activation of gene expression. (PubMed id 11329013)1 Harrington J.J.... Ducar M. (2001)
    10. A new locus for autosomal dominant high myopia maps to 4q22-q27 between D4S1578 and D4S1612. (PubMed id 16052171)9 Zhang Q....Hejtmancik J.F. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10692 HGNC: 10450 AceView: RRH Ensembl:ENSG00000180245 euGenes: HUgn10692
    ECgene: RRH H-InvDB: RRH

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RRH Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RRH gene:
    Search GeneIP for patents involving RRH

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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