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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RRBP1 Gene

protein-coding   GIFtS: 61
GCID: GC20M017594

Ribosome Binding Protein 1

(Previous names: ribosome binding protein 1 (dog 180kD homolog), ribosome...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ribosome Binding Protein 11 2     ES1302 5
Ribosome Binding Protein 1 Homolog 180kDa (Dog)1 2     Ribosome Binding Protein 1 (Dog 180kD Homolog)1
Ribosome Receptor Protein2 3     ES/1302
180 KDa Ribosome Receptor Homolog2 3     hES2
RRp2 3     Ribosome-Binding Protein 12
ES/130-Related Protein2 3     KIAA13983

External Ids:    HGNC: 104481   Entrez Gene: 62382   Ensembl: ENSG000001258447   OMIM: 6014185   UniProtKB: Q9P2E93   

Export aliases for RRBP1 gene to outside databases

Previous GC identifers: GC20M017582 GC20M017589 GC20M017542 GC20M017557


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RRBP1 Gene:
This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this
gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of
ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by
regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in
variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ
in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7,
and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a
nearby gene on chromosome 20p12. (provided by RefSeq, Apr 2012)

GeneCards Summary for RRBP1 Gene: 
RRBP1 (ribosome binding protein 1) is a protein-coding gene. Diseases associated with RRBP1 include anuria, and alagille syndrome. GO annotations related to this gene include receptor activity. An important paralog of this gene is KTN1.

UniProtKB/Swiss-Prot: RRBP1_HUMAN, Q9P2E9
Function: Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum
membrane (By similarity)

Gene Wiki entry for RRBP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NT_011387.8  NC_018931.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RRBP1 gene promoter:
         c-Fos   AhR   GR   AP-1   ATF-2   STAT3   c-Jun   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRRBP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for RRBP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RRBP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p12   Ensembl cytogenetic band:  20p12.1   HGNC cytogenetic band: 20p12

RRBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RRBP1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M017594:  view genomic region     (about GC identifiers)

Start:
17,594,323 bp from pter      End:
17,662,940 bp from pter
Size:
68,618 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RRBP1_HUMAN, Q9P2E9 (See protein sequence)
Recommended Name: Ribosome-binding protein 1  
Size: 1410 amino acids; 152472 Da
Subcellular location: Endoplasmic reticulum membrane; Single-pass type III membrane protein (By similarity)
Sequence caution: Sequence=BAA92636.2; Type=Erroneous initiation;
Secondary accessions: A2A2S6 A6NCN6 O75300 O75301 Q5W165 Q96SB2 Q9BWP1 Q9H476
Alternative splicing: 3 isoforms:  Q9P2E9-1   Q9P2E9-2   Q9P2E9-3   

Explore the universe of human proteins at neXtProt for RRBP1: NX_Q9P2E9

Explore proteomics data for RRBP1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9P2E9

  • RRBP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RRBP1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001036041.1  NP_004578.2  

    ENSEMBL proteins: 
     ENSP00000367044   ENSP00000354045   ENSP00000381762   ENSP00000367038   ENSP00000246043  
     ENSP00000401206  

    Human Recombinant Protein Products for RRBP1: 
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    Cloud-Clone Corp. Proteins for RRBP1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IDA--
    GO:0005840ribosome TAS9628588
    GO:0030176integral to endoplasmic reticulum membrane NAS--

    RRBP1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR007794 Rib_rcpt_KP

    Graphical View of Domain Structure for InterPro Entry Q9P2E9

    ProtoNet protein and cluster: Q9P2E9


    RRBP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RRBP1_HUMAN, Q9P2E9
    Function: Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum
    membrane (By similarity)

         Genatlas biochemistry entry for RRBP1:
    ribosome binding protein 1

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity TAS9628588
         
    RRBP1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RRBP1:
     Decreased circadian period len 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RRBP1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RRBP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RRBP1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RRBP1 

    miRNA
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    miRTarBase miRNAs that target RRBP1:
    hsa-mir-1 (MIRT005285)

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    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate RRBP1 (see all 18):
    hsa-miR-3910 hsa-miR-25 hsa-miR-124 hsa-miR-4325 hsa-miR-3116 hsa-miR-506 hsa-miR-613 hsa-miR-92b
    SwitchGear 3'UTR luciferase reporter plasmidRRBP1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RRBP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RRBP1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Protein processing in endoplasmic reticulum
    Protein processing in endoplasmic reticulum

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for RRBP1):
        Protein processing in endoplasmic reticulum


    RRBP1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RRBP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/19 Interacting proteins for RRBP1 (Q9P2E92, 3 ENSP000003540454) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATF7IPQ6VMQ62, 3MINT-61929 I2D: score=3 
    SMAD9O151982, 3MINT-62150 I2D: score=3 
    PRKD2Q9BZL62, 3MINT-61763 I2D: score=2 
    ZWINTO952293, ENSP000003630554I2D: score=2 STRING: ENSP00000363055
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation TAS9628588
    GO:0007165signal transduction NAS--
    GO:0015031protein transport IEA--

    RRBP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RRBP1

    Search CenterWatch for drugs/clinical trials and news about RRBP1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RRBP1 gene (2 alternative transcripts): 
    NM_001042576.1  NM_004587.2  

    Unigene Cluster for RRBP1:

    Ribosome binding protein 1
    Hs.472213  [show with all ESTs]
    Unigene Representative Sequence: AB037819
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000468428(uc010zrp.1) ENST00000470422(uc002wpt.1) ENST00000377813(uc010zrq.1 uc010zrr.1)
    ENST00000360807(uc002wpw.1) ENST00000495501 ENST00000398782 ENST00000377807(uc002wpv.1 uc010gcl.1)
    ENST00000246043(uc002wpu.3) ENST00000455029(uc010gcm.1)
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RRBP1
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate RRBP1 (see all 18):
    hsa-miR-3910 hsa-miR-25 hsa-miR-124 hsa-miR-4325 hsa-miR-3116 hsa-miR-506 hsa-miR-613 hsa-miR-92b
    SwitchGear 3'UTR luciferase reporter plasmidRRBP1 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RRBP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RRBP1

    Additional mRNA sequence: 

    AB037819.2 AB287347.2 AF006751.1 AF007575.1 AK093465.1 AK098319.1 AK309197.1 AL833822.1 
    BC000099.2 BC009700.1 BC020482.1 BC080526.1 BC108741.1 BC128577.1 BC128578.1 

    24/26 DOTS entries (see all 26):

    DT.95368057  DT.213446  DT.91669694  DT.100842247  DT.95368060  DT.75121014  DT.91742123  DT.99956110 
    DT.100842239  DT.100842236  DT.100044602  DT.120834813  DT.120834857  DT.100842233  DT.120834876  DT.100842240 
    DT.120834828  DT.120834878  DT.95368058  DT.100044605  DT.100842234  DT.91705773  DT.92448940  DT.95099927 

    24/428 AceView cDNA sequences (see all 428):

    AI669213 AW118981 BQ685801 AI074124 BQ931525 BI712830 AL712146 CA447002 
    BU854882 AA745923 AI810890 BG326657 BQ002959 BF514727 BF508366 BQ070387 
    BI793160 BC000099 BQ424709 BU902078 AA158569 BM797951 D31117 R81516 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for RRBP1 (see all 13)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^
    SP1:                                                                                                                          -                 -               
    SP2:                                                                    -                                                     -                 -               
    SP3:                                                                                                                                                            
    SP4:                                                                    -                                                                                       
    SP5:                                                                                                                                                            

    ExUns: 19 ^ 20 ^ 21 ^ 22a · 22b ^ 23 ^ 24a · 24b ^ 25 ^ 26 ^ 27 ^ 28a · 28b · 28c
    SP1:                    -                                                               
    SP2:                    -                                                               
    SP3:                    -                                                               
    SP4:                                                                                    
    SP5:                                                                                    


    ECgene alternative splicing isoforms for RRBP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RRBP1 expression in normal human tissues (normalized intensities)      RRBP1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAGACAAGT
    RRBP1 Expression
    About this image


    RRBP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/33 selected tissues (see all 33) fully expand
     
     Uterus
             uterus, post-menopause ; glandular cells   
             endometrial endothelial cell   
     
     Epithelium (Reproductive System)    fully expand to see all 5 entries
             vagina ; squamous epithelial cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Lung (Respiratory System)    fully expand to see all 4 entries
             lung ; pneumocytes   
             trachea   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   

    See RRBP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RRBP1

    SOURCE GeneReport for Unigene cluster: Hs.472213
        SABiosciences Custom PCR Arrays for RRBP1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RRBP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RRBP1 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rrbp15 ribosome binding protein 1   --   2 (70.89 cM) 143947395 
    chicken
    (Gallus gallus)
    Aves RRBP16
    ribosome-binding protein 1
    62(a)
    1 ↔ 1
    3(14871338-14889265)
    lizard
    (Anolis carolinensis)
    Reptilia RRBP16
    Uncharacterized protein
    45(a)
    1 ↔ 1
    4(74337579-74374986)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC059298.12   -- 73.08(n)    BC059298.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC054580.12   -- 75.06(n)   368324  BC054580.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta alt1 aluminum tubes 42.57(n)
    27.41(a)
      42127  NM_206505.1  NP_996227.1 
    A. gossypii yeast
    (Ashbya gossypii)
    Saccharomycetes AGOS_AGR229W1 AGR229Wp 44.69(n)
    26.69(a)
      4623197  NM_211957.1  NP_986895.1 


    ENSEMBL Gene Tree for RRBP1 (if available)
    TreeFam Gene Tree for RRBP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RRBP1 gene
    KTN12  
    1 SIMAP similar gene for RRBP1 using alignment to 8 protein entries:     RRBP1_HUMAN (see all proteins):
    KTN1

    RRBP1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for RRBP1
    PGOHUM00000259820 PGOHUM00000233229


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1889 SNPs in RRBP1 are shown (see all 1889)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs777652711,2
    C,F--17593833(+) GGGTCG/ATGGCA 2 -- ds50011Minor allele frequency- A:0.03WA 118
    rs1174700441,2
    F--17593849(+) AAGCTG/CGTTTC 2 -- ds50011Minor allele frequency- C:0.01NA 120
    rs1881123631,2
    --17593971(+) TTCCCA/GGACCT 2 -- ds50010--------
    rs1397984851,2
    C--17593978(+) ACCTC-/CATCACGC 2 -- ds50010--------
    rs2003930161,2
    --17593980(+) CTCCA-/TCACGC 2 -- ds50010--------
    rs18850821,2
    C,F,O,A,H--17593984(+) ATCACA/GCAACA 2 -- ds500133Minor allele frequency- N:0.00NS EA NA WA CSA 2880
    rs580784621,2
    C,F--17594006(+) CAGCCG/ACGCTC 2 -- ds50012Minor allele frequency- A:0.04WA 120
    rs60449081,2
    C,F,H--17594007(+) AGCCGC/TGCTCA 2 -- ds500113Minor allele frequency- T:0.14NS EA NA WA CSA 553
    rs61361491,2
    C,F,A,H--17594030(+) CCTCCA/GGGATG 2 -- ds500116Minor allele frequency- G:0.44NS EA NA WA CSA 743
    rs758765871,2
    F--17594036(+) GGATGC/TGGGGC 2 -- ds50011Minor allele frequency- T:0.02WA 118

    HapMap Linkage Disequilibrium report for RRBP1 (17594323 - 17662940 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for RRBP1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1521395CNV Insertion17803354
    nsv3311CNV Insertion18451855
    dgv4556n71CNV Loss21882294
    dgv4557n71CNV Loss21882294
    nsv458943CNV Loss19166990
    nsv180652CNV Loss16902084
    nsv519542CNV Loss19592680
    nsv527274CNV Loss19592680
    nsv828695CNV Gain20364138
    esv23450CNV Gain19812545

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 601418    OMIM disorders: --

    5 diseases for RRBP1:    About MalaCards
    anuria    alagille syndrome    colorectal cancer    glioblastoma
    neuronitis

    2 diseases from the University of Copenhagen DISEASES database for RRBP1:
    Anuria     Kidney failure

    RRBP1 for disorders           About GeneDecksing


    Export disorders for RRBP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RRBP1 gene, integrated from 9 sources (see all 65):
    (articles sorted by number of sources associating them with RRBP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    6. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (2000)
    7. Identification of multiple forms of 180-kDa ribosome receptor in human cells. (PubMed id 9628588)1, 2 Langley R.... Krissansen G.W. (1998)
    8. Identification, characterization, and chromosomal localization of the human homolog (hES) of ES/130. (PubMed id 8812507)1, 3 Basson C.T....Seidman C.E. (1996)
    9. Autophagy negatively regulates cancer cell proliferati on via selectively targeting VPRBP. (PubMed id 22963397)1 Wang B.S....Wang M.R. (2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6238 HGNC: 10448 AceView: RRBP1 Ensembl:ENSG00000125844 euGenes: HUgn6238
    ECgene: RRBP1 Kegg: 6238 H-InvDB: RRBP1

    (According to HUGE)
    About This Section
    HUGE: KIAA1398

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RRBP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RRBP1 gene:
    Search GeneIP for patents involving RRBP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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