Aliases for RRAS Gene
External Ids for RRAS Gene
Previous GeneCards Identifiers for RRAS Gene
The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015]
GeneCards Summary for RRAS Gene
RRAS (RAS Related) is a Protein Coding gene. Diseases associated with RRAS include Noonan Syndrome 1 and Juvenile Myelomonocytic Leukemia. Among its related pathways are Arrhythmogenic right ventricular cardiomyopathy (ARVC) and Semaphorin interactions. GO annotations related to this gene include GTP binding and protein complex binding. An important paralog of this gene is RRAS2.
UniProtKB/Swiss-Prot for RRAS Gene
Regulates the organization of the actin cytoskeleton (PubMed:16537651, PubMed:18270267). With OSPBL3, modulates integrin beta-1 (ITGB1) activity (PubMed:18270267).