Aliases for RRAGD Gene
External Ids for RRAGD Gene
Previous GeneCards Identifiers for RRAGD Gene
RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004]
GeneCards Summary for RRAGD Gene
RRAGD (Ras Related GTP Binding D) is a Protein Coding gene. Diseases associated with RRAGD include Omenn Syndrome. Among its related pathways are Gene Expression and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include protein heterodimerization activity and GTPase activity. An important paralog of this gene is RRAGC.
UniProtKB/Swiss-Prot for RRAGD Gene
Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.