Aliases for RRAGD Gene
External Ids for RRAGD Gene
Previous GeneCards Identifiers for RRAGD Gene
RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004]
GeneCards Summary for RRAGD Gene
RRAGD (Ras Related GTP Binding D) is a Protein Coding gene. Diseases associated with RRAGD include Omenn Syndrome. Among its related pathways are Cellular Senescence and mTOR signalling. GO annotations related to this gene include protein heterodimerization activity and GTPase activity. An important paralog of this gene is RRAGC.
UniProtKB/Swiss-Prot for RRAGD Gene
Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.