Aliases for RRAGC Gene
External Ids for RRAGC Gene
Previous GeneCards Identifiers for RRAGC Gene
This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
GeneCards Summary for RRAGC Gene
RRAGC (Ras-Related GTP Binding C) is a Protein Coding gene. Among its related pathways are Translational Control and Insulin receptor signalling cascade. GO annotations related to this gene include protein heterodimerization activity and GTPase activity. An important paralog of this gene is RRAGD.
UniProtKB/Swiss-Prot for RRAGC Gene
Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.