Aliases for RRAGC Gene
External Ids for RRAGC Gene
Previous GeneCards Identifiers for RRAGC Gene
This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
GeneCards Summary for RRAGC Gene
RRAGC (Ras Related GTP Binding C) is a Protein Coding gene. Among its related pathways are Gene Expression and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include protein heterodimerization activity and GTPase activity. An important paralog of this gene is RRAGD.
UniProtKB/Swiss-Prot for RRAGC Gene
Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.