Aliases for RRAGA Gene
External Ids for RRAGA Gene
GeneCards Summary for RRAGA Gene
RRAGA (Ras-Related GTP Binding A) is a Protein Coding gene. Among its related pathways are Translational Control and Insulin receptor signalling cascade. GO annotations related to this gene include protein homodimerization activity and GTP binding. An important paralog of this gene is RRAGB.
UniProtKB/Swiss-Prot for RRAGA Gene
Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.