Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RPSAP58 Gene

Aliases for RPSAP58 Gene

  • Ribosomal Protein SA Pseudogene 58 2 3 5
  • RPSA_30_1642 3

External Ids for RPSAP58 Gene

Previous GeneCards Identifiers for RPSAP58 Gene

  • GC19U901020
  • GC19P023946
  • GC19P023490

Summaries for RPSAP58 Gene

GeneCards Summary for RPSAP58 Gene

RPSAP58 (Ribosomal Protein SA Pseudogene 58) is a Pseudogene. GO annotations related to this gene include structural constituent of ribosome and laminin receptor activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPSAP58 Gene

Genomics for RPSAP58 Gene

Regulatory Elements for RPSAP58 Gene

Enhancers for RPSAP58 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F023762 0.9 ENCODE 0.8 +0.7 745 2.8 TBP CREB3L1 NFRKB RAD21 YY1 CHAMP1 ZNF121 FOS ZBTB2 SMAD5 ENSG00000233836 LINC01224 RPSAP58 GC19M023775
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around RPSAP58 on UCSC Golden Path with GeneCards custom track

Promoters for RPSAP58 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000141528 686 2600 TBP CREB3L1 NFRKB RAD21 YY1 CHAMP1 ZNF121 FOS ZBTB2 SMAD5

Genomic Location for RPSAP58 Gene

23,763,014 bp from pter
23,828,135 bp from pter
65,122 bases
Plus strand

Genomic View for RPSAP58 Gene

Genes around RPSAP58 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RPSAP58 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RPSAP58 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPSAP58 Gene

Proteins for RPSAP58 Gene

Post-translational modifications for RPSAP58 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RPSAP58 Gene

Domains & Families for RPSAP58 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RPSAP58 Gene

Function for RPSAP58 Gene

Phenotypes for RPSAP58 Gene

genes like me logo Genes that share phenotypes with RPSAP58: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RPSAP58 Gene

Localization for RPSAP58 Gene

Subcellular locations from

Jensen Localization Image for RPSAP58 Gene COMPARTMENTS Subcellular localization image for RPSAP58 gene
Compartment Confidence
cytosol 3
extracellular 2
nucleus 2
cytoskeleton 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RPSAP58 Gene

Pathways & Interactions for RPSAP58 Gene

SuperPathways for RPSAP58 Gene

No Data Available

Interacting Proteins for RPSAP58 Gene

Gene Ontology (GO) - Biological Process for RPSAP58 Gene


No data available for Pathways by source and SIGNOR curated interactions for RPSAP58 Gene

Transcripts for RPSAP58 Gene

mRNA/cDNA for RPSAP58 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2931) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RPSAP58 Gene

Ribosomal protein SA pseudogene 58:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RPSAP58 Gene

No ASD Table

Relevant External Links for RPSAP58 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RPSAP58 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RPSAP58 Gene

Protein differential expression in normal tissues from HIPED for RPSAP58 Gene

This gene is overexpressed in Skin (41.1), Heart (17.0), and Saliva (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for RPSAP58 Gene

Protein tissue co-expression partners for RPSAP58 Gene

NURSA nuclear receptor signaling pathways regulating expression of RPSAP58 Gene:


SOURCE GeneReport for Unigene cluster for RPSAP58 Gene:

genes like me logo Genes that share expression patterns with RPSAP58: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RPSAP58 Gene

Orthologs for RPSAP58 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RPSAP58 Gene

Organism Taxonomy Gene Similarity Type Details
(Danio rerio)
Actinopterygii zgc55831 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.508 34
(Glycine max)
eudicotyledons Gma.3328 34
Species where no ortholog for RPSAP58 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RPSAP58 Gene

Gene Tree for RPSAP58 (if available)
Gene Tree for RPSAP58 (if available)

Paralogs for RPSAP58 Gene

(2) SIMAP similar genes for RPSAP58 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with RPSAP58: view

No data available for Paralogs for RPSAP58 Gene

Variants for RPSAP58 Gene

Sequence variations from dbSNP and Humsavar for RPSAP58 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10404600 -- 23,811,633(+) TTTAC(A/G)TGTTG intron-variant
rs10405273 -- 23,811,921(+) TTAAA(A/G)GTTTC intron-variant
rs10405659 -- 23,766,271(+) ccgca(A/G)cctcc intron-variant
rs10405957 -- 23,775,135(+) ggtac(A/G)gagag intron-variant
rs10406852 -- 23,791,198(+) aattt(A/G)tggtc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RPSAP58 Gene

Variant ID Type Subtype PubMed ID
dgv1741n106 OTHER inversion 24896259
dgv1743n106 CNV deletion 24896259
dgv3479n100 CNV loss 25217958
dgv3481n100 CNV gain 25217958
dgv3482n100 CNV loss 25217958
dgv515e201 CNV deletion 23290073
dgv6344n54 CNV loss 21841781
esv2268001 CNV deletion 18987734
esv2619335 CNV deletion 19546169
esv2670676 CNV deletion 23128226
esv2677185 CNV deletion 23128226
esv2718381 CNV deletion 23290073
esv2718383 CNV deletion 23290073
esv2718386 CNV deletion 23290073
esv2751784 CNV gain 17911159
esv2762030 CNV gain 21179565
esv3556216 CNV deletion 23714750
esv3574386 CNV gain 25503493
esv3583313 CNV loss 25503493
esv3644015 CNV loss 21293372
esv3644021 CNV loss 21293372
esv3644022 CNV loss 21293372
esv3644023 CNV gain 21293372
esv3893187 CNV gain 25118596
esv4296 OTHER complex 18987735
esv9336 CNV loss 19470904
nsv1057420 CNV gain 25217958
nsv1057423 CNV gain 25217958
nsv1058651 CNV loss 25217958
nsv1059501 CNV loss 25217958
nsv1072874 CNV deletion 25765185
nsv1078888 OTHER inversion 25765185
nsv1116315 CNV deletion 24896259
nsv1134777 CNV deletion 24896259
nsv1153393 OTHER inversion 26484159
nsv138104 CNV deletion 16902084
nsv138127 CNV deletion 16902084
nsv2448 CNV insertion 18451855
nsv524183 CNV gain 19592680
nsv956591 CNV deletion 24416366
nsv960819 CNV duplication 23825009

Variation tolerance for RPSAP58 Gene

Gene Damage Index Score: 11.48; 92.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RPSAP58 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPSAP58 Gene

Disorders for RPSAP58 Gene

Relevant External Links for RPSAP58

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RPSAP58 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RPSAP58 Gene

Publications for RPSAP58 Gene

  1. Comparative analysis of processed ribosomal protein pseudogenes in four mammalian genomes. (PMID: 19123937) Balasubramanian S. … Gerstein M. (Genome Biol. 2009) 2 3 64
  2. Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. (PMID: 25963833) Drissi R. … Boisvert F.M. (Mol. Cell Proteomics 2015) 3 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover. (PMID: 24999758) Elzi D.J. … Shiio Y. (J. Proteome Res. 2014) 3 64
  5. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3 64

Products for RPSAP58 Gene

Sources for RPSAP58 Gene

Loading form....