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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPS6KC1 Gene

protein-coding   GIFtS: 53
GCID: GC01P213224

Ribosomal Protein S6 Kinase, 52kDa, Polypeptide 1

(Previous names: ribosomal protein S6 kinase, 52kD, polypeptide 1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ribosomal Protein S6 Kinase, 52kDa, Polypeptide 11 2     SPHK1-Binding Protein2 3
Ribosomal S6 Kinase-Like Protein With Two PSK Domains 118 KDa Protein2 3     Ribosomal Protein S6 Kinase, 52kD, Polypeptide 11
52 KDa Ribosomal Protein S6 Kinase2 3     humS6PKh12
RPK1182 3     Ribosomal Protein S6 Kinase Delta-12
S6K-delta-12 3     EC 2.7.11.13

External Ids:    HGNC: 104391   Entrez Gene: 267502   Ensembl: ENSG000001366437   UniProtKB: Q96S383   

Export aliases for RPS6KC1 gene to outside databases

Previous GC identifers: GC01P212070 GC01P209067 GC01P209840 GC01P210281 GC01P209612 GC01P211291 GC01P183899


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RPS6KC1 Gene: 
RPS6KC1 (ribosomal protein S6 kinase, 52kDa, polypeptide 1) is a protein-coding gene. Diseases associated with RPS6KC1 include paraplegia, and spasticity, and among its related super-pathways are Nanog in Mammalian ESC Pluripotency and CNTF Signaling. GO annotations related to this gene include protein serine/threonine kinase activity and phosphatidylinositol binding. An important paralog of this gene is RPS6KL1.

UniProtKB/Swiss-Prot: KS6C1_HUMAN, Q96S38
Function: May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell

Gene Wiki entry for RPS6KC1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_167186.1  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPS6KC1 gene promoter:
         MEF-2A   Elk-1   NRF-2   MEF-2   Olf-1   LCR-F1   Egr-4   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS6KC1 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPS6KC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS6KC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q41   Ensembl cytogenetic band:  1q32.3   HGNC cytogenetic band: 1q41

RPS6KC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS6KC1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P213224:  view genomic region     (about GC identifiers)

Start:
213,224,588 bp from pter      End:
213,448,116 bp from pter
Size:
223,529 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KS6C1_HUMAN, Q96S38 (See protein sequence)
Recommended Name: Ribosomal protein S6 kinase delta-1  
Size: 1066 amino acids; 118682 Da
Subunit: Interacts with SPHK1 and phosphatidylinositol 3-phosphate
Subcellular location: Cytoplasm. Membrane. Note=Also found in some small dot-like or ring-shaped early endosome
structures
Caution: Instead of Lys-820, Arg-820 is found at the binding site
Sequence caution: Sequence=CAB92850.1; Type=Erroneous initiation;
Secondary accessions: B1APS8 B3KVM4 D3DTA4 Q8TDD3 Q9NSF4 Q9UL66
Alternative splicing: 2 isoforms:  Q96S38-1   Q96S38-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RPS6KC1: NX_Q96S38

Explore proteomics data for RPS6KC1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96S38

  • RPS6KC1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RPS6KC1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001129610.1  NP_036556.2  

    ENSEMBL proteins: 
     ENSP00000355927   ENSP00000355926   ENSP00000442306   ENSP00000439282  

    Human Recombinant Protein Products for RPS6KC1: 
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    Cloud-Clone Corp. Proteins for RPS6KC1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005769early endosome IDA15750338
    GO:0005840ribosome ----
    GO:0016020membrane IEA--

    RPS6KC1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: ribosomal protein S6 kinase, 52kDa, polypeptide 1 
    RSKL family
    Other AGC kinases

    4 InterPro protein domains:
     IPR001683 Phox
     IPR011009 Kinase-like_dom
     IPR000719 Prot_kinase_cat_dom
     IPR007330 MIT

    Graphical View of Domain Structure for InterPro Entry Q96S38

    ProtoNet protein and cluster: Q96S38

    1 Blocks protein domain: IPB001683 Phox-like

    UniProtKB/Swiss-Prot: KS6C1_HUMAN, Q96S38
    Domain: The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical
    characteristics, such as the ATP-binding motif, ATP-binding site and active site
    Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily
    Similarity: Contains 1 MIT domain
    Similarity: Contains 2 protein kinase domains
    Similarity: Contains 1 PX (phox homology) domain


    RPS6KC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KS6C1_HUMAN, Q96S38
    Function: May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

         Genatlas biochemistry entry for RPS6KC1:
    ribosomal protein S6 kinase,polypeptide 1,expressed highly in testis,skeletal muscle,brain and pancreas,not
    involved in vivo in the phosphorylation of RPS6,mediating protein synthesis initiation and elongation induced by
    hormones or growth factors,maybe playing an essentilal regulatory role in protein synthesis during cell
    proliferation

         Enzyme Number (IUBMB): EC 2.7.11.11

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0005515protein binding IPI15750338
    GO:0005524ATP binding IEA--
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
         
    RPS6KC1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for RPS6KC1:
     Decreased Wnt reporter activit  Elongated cells 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RPS6KC1 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPS6KC1 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RPS6KC1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Nanog in Mammalian ESC Pluripotency
    14-3-3 Induced Intracellular Signaling0.59
    2CNTF Signaling
    FLT3 Signaling0.50

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for RPS6KC1
        FLT3 Signaling
    14-3-3 Induced Intracellular Signaling


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RPS6KC1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/16 Interacting proteins for RPS6KC1 (Q96S382, 3 ENSP000003559274) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000225987P404252, 3, ENSP000004039484MINT-62747 MINT-62671 MINT-62573 I2D: score=4 STRING: ENSP00000403948
    ENSG00000237344P404252, 3, ENSP000003971774MINT-62747 MINT-62671 MINT-62573 I2D: score=4 STRING: ENSP00000397177
    PBX2P404252, 3, ENSP000003641904MINT-62747 MINT-62671 MINT-62573 I2D: score=4 STRING: ENSP00000364190
    ENSG00000206315P404252, 3MINT-62747 MINT-62671 MINT-62573 I2D: score=4 
    ENSG00000224952P404252, 3MINT-62747 MINT-62671 MINT-62573 I2D: score=4 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----
    GO:0007154cell communication ----
    GO:0007165signal transduction TAS10552933

    RPS6KC1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPS6KC1 (KS6C1)

    Search CenterWatch for drugs/clinical trials and news about RPS6KC1 / KS6C1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPS6KC1 gene (2 alternative transcripts): 
    NM_001136138.1  NM_012424.3  

    Unigene Cluster for RPS6KC1:

    Ribosomal protein S6 kinase, 52kDa, polypeptide 1
    Hs.591416  [show with all ESTs]
    Unigene Representative Sequence: NM_012424
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000366960(uc010ptr.2 uc010pts.2 uc010ptt.2 uc010ptu.2 uc010ptv.2)
    ENST00000366959(uc001hkd.3) ENST00000490299(uc001hke.3) ENST00000468069
    ENST00000491616 ENST00000543470(uc009xdh.2 uc009xdi.1) ENST00000543354

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    Additional mRNA sequence: 

    AB070706.1 AF037447.1 AF477978.1 AK122921.1 AK122989.1 AK130279.1 AK295053.1 AK299298.1 
    AL356893.1 BC104769.1 BC143449.1 BC143473.1 BC143474.1 BX647303.1 EF491805.1 EF491820.1 

    9 DOTS entries:

    DT.213470  DT.92334640  DT.101971020  DT.101969674  DT.40275803  DT.121362049  DT.75151904  DT.100749650 
    DT.40266310 

    24/108 AceView cDNA sequences (see all 108):

    AA774170 CA771867 CB529015 AI874333 BQ183843 AA788825 CA773539 AI740675 
    BM678614 AA670286 CA772736 BF439060 BP378802 AW591866 CA436918 AI190238 
    BX098178 AI370125 BM793456 BM452011 BQ446176 W21053 AA102718 BI915114 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RPS6KC1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b
    SP1:              -                                                     -                                             
    SP2:        -     -                                                     -                                             
    SP3:                                -                                   -                                             
    SP4:                                                                                                                  


    ECgene alternative splicing isoforms for RPS6KC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPS6KC1 expression in normal human tissues (normalized intensities)      RPS6KC1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGAAACATT
    RPS6KC1 Expression
    About this image


    RPS6KC1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Nose (Sensory Organs)    fully expand to see all 2 entries
             sensory organ/nose/nasal cavity   
     
     Neural Crest (Sensory Organs)
             sensory organ/nose/vomeronasal organ   
     
     Testis (Reproductive System)
             sperm   
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood

    See RPS6KC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPS6KC1

    SOURCE GeneReport for Unigene cluster: Hs.591416

    UniProtKB/Swiss-Prot: KS6C1_HUMAN, Q96S38
    Tissue specificity: Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and
    weakly expressed in thymus, small intestine, lung and colon

        SABiosciences Custom PCR Arrays for RPS6KC1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS6KC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RPS6KC1 gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rps6kc11 , 5 ribosomal protein S6 kinase polypeptide 11, 5 79.81(n)1
    79.34(a)1
      1 (96.20 cM)5
    3201191  NM_178775.41  NP_848890.31 
     1907002025 
    chicken
    (Gallus gallus)
    Aves RPS6KC11 ribosomal protein S6 kinase, 52kDa, polypeptide 1 74.94(n)
    71.92(a)
      421362  XM_419422.3  XP_419422.3 
    lizard
    (Anolis carolinensis)
    Reptilia RPS6KC16
    Uncharacterized protein
    68(a)
    1 ↔ 1
    1(238840457-238968557)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ626358.12   -- 76.8(n)    BJ626358.1 
    zebrafish
    (Danio rerio)
    Actinopterygii RPS6KC16
    ribosomal protein S6 kinase, 52kDa, polypeptide 1
    50(a)
    1 ↔ 1
    20(3267516-3315107)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG71561 CG7156 43.2(n)
    33.75(a)
      42187  NM_142440.2  NP_650697.1 
    worm
    (Caenorhabditis elegans)
    Secernentea rskd-16
    Protein RSKD-1, isoform a
    14(a)
    1 → many
    V(12284058-12288617)


    ENSEMBL Gene Tree for RPS6KC1 (if available)
    TreeFam Gene Tree for RPS6KC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPS6KC1 gene
    RPS6KL12  SNX152  
    4 SIMAP similar genes for RPS6KC1 using alignment to 3 protein entries:     KS6C1_HUMAN (see all proteins):
    RPS6KA1    RPS6KL1    RPS6KA2    SNX15

    RPS6KC1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3905 SNPs in RPS6KC1 are shown (see all 3905)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0406544
    An ovarian mucinous carcinoma sample4--see VAR_0406542 G A mis40--------
    VAR_0406574
    A breast infiltrating ductal carcinoma sample4--see VAR_0406572 E K mis40--------
    VAR_0406524
    A lung neuroendocrine carcinoma sample4--see VAR_0406522 L I mis40--------
    VAR_0406564
    A lung adenocarcinoma sample4--see VAR_0406562 C Y mis40--------
    rs105248841,2
    C--183967596(+) tatat-/ATATATATATATATATATATATATATATATATATAT/ATATATATATATATATATATATAT
    ATATATATATATATAT
    /ATATATATATATATATATATATATATATATATATATATATATATAT
    GAGAG
    4 -- int1 cds11NA 2
    rs741405551,2
    C,F--213222635(+) AAAAAG/AAGCAA 2 -- us2k12Minor allele frequency- A:0.08WA 120
    rs798857311,2
    C,F--213222690(+) ATGCTA/GAGAAT 2 -- us2k11Minor allele frequency- G:0.02EA 120
    rs1467815131,2
    --213223128(+) CTAGAC/TGGTAC 2 -- us2k10--------
    rs3686963881,2
    C--213223153(+) TATCT-/CCTTTT 2 -- us2k10--------
    rs113955551,2
    C,F--213223156(+) CTACCC/TTTTTT 2 -- us2k1 trp36Minor allele frequency- T:0.36NA WA CSA 11

    HapMap Linkage Disequilibrium report for RPS6KC1 (213224588 - 213448116 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for RPS6KC1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2671923CNV Deletion23128226
    esv2666633CNV Deletion23128226
    esv2675698CNV Deletion23128226
    nsv4476CNV Insertion18451855
    nsv508693CNV Loss20534489
    nsv826598CNV Loss20364138
    nsv508692CNV Loss20534489
    esv28931CNV Loss19812545
    esv1004277CNV Gain20482838
    esv275574CNV Gain+Loss21479260

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for RPS6KC1:    About MalaCards
    paraplegia    spasticity


    RPS6KC1 for disorders           About GeneDecksing


    Export disorders for RPS6KC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPS6KC1 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with RPS6KC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, characterization, and chromosome mapping of RPS6KC1, a novel putative member of the ribosome protein S6 kinase family, to chromosome 12q12-q13.1. (PubMed id 10552933)1, 2, 3 Zhang H.... Zhao S. (1999)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein. (PubMed id 12077123)1, 2 Hayashi S....Nakamura S. (2002)
    6. Quantitative analysis of HSP90-client interactions rev eals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (2012)
    7. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    8. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    9. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26750 HGNC: 10439 AceView: RPS6KC1 Ensembl:ENSG00000136643 euGenes: HUgn26750
    ECgene: RPS6KC1 H-InvDB: RPS6KC1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPS6KC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPS6KC1 gene:
    Search GeneIP for patents involving RPS6KC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

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