Aliases for RPS6KC1 Gene
Aliases for RPS6KC1 Gene
External Ids for RPS6KC1 Gene
- HGNC: 10439
- Entrez Gene: 26750
- Ensembl: ENSG00000136643
- UniProtKB: Q96S38
Previous GeneCards Identifiers for RPS6KC1 Gene
- GC01P212070
- GC01P209067
- GC01P209840
- GC01P210281
- GC01P209612
- GC01P211291
- GC01P213224
- GC01P183899
Summaries for RPS6KC1 Gene
-
Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017]
GeneCards Summary for RPS6KC1 Gene
RPS6KC1 (Ribosomal Protein S6 Kinase C1) is a Protein Coding gene. Among its related pathways are Nanog in Mammalian ESC Pluripotency and CNTF Signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein serine/threonine kinase activity. An important paralog of this gene is RPS6KL1.
UniProtKB/Swiss-Prot for RPS6KC1 Gene
-
May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPS6KC1 Gene
Genomics for RPS6KC1 Gene
Regulatory Elements for RPS6KC1 Gene
Enhancers for RPS6KC1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G213050 | 1.1 | ENCODE | 39.5 | +0.5 | 489 | 3.1 | HDGF PKNOX1 MLX CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 ZNF766 | RPS6KC1 ANGEL2 PPP2R5A GC01P213058 |
| GH01G212977 | 1.7 | FANTOM5 Ensembl ENCODE dbSUPER | 20.8 | -71.1 | -71085 | 5.6 | HDAC1 TBP FOXA2 CBX3 TBL1XR1 WRNIP1 BMI1 EGR1 ZNF207 RELB | RPS6KC1 VASH2 BATF3 ANGEL2 TATDN3 |
| GH01G213008 | 0.6 | ENCODE | 37.1 | -42.5 | -42480 | 0.2 | PKNOX1 MTA2 RELB DPF2 NFE2 TBX21 SPI1 | RPS6KC1 VASH2 ANGEL2 |
| GH01G212634 | 1.9 | FANTOM5 Ensembl ENCODE dbSUPER | 6.5 | -413.9 | -413861 | 5.7 | ATF1 CREB3L1 ARNT SIN3A FEZF1 TCF12 ZNF766 GLIS2 ELK1 GATA2 | ATF3 BATF3 RPS6KC1 FLVCR1-AS1 TATDN3 PPP2R5A VASH2 LOC105372909 ENSG00000235862 |
| GH01G212949 | 1.8 | FANTOM5 Ensembl ENCODE dbSUPER | 6 | -97.9 | -97948 | 6.6 | HDGF PKNOX1 ATF1 ARNT WRNIP1 ZNF2 TCF12 GLIS2 GATA2 FOS | VASH2 RPS6KC1 TATDN3 ANGEL2 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around RPS6KC1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the RPS6KC1 gene promoter:
Regulatory Element Products
Genomic Location for RPS6KC1 Gene
- Chromosome:
- 1
- Start:
- 213,051,233 bp from pter
- End:
- 213,274,773 bp from pter
- Size:
- 223,541 bases
- Orientation:
- Plus strand
Genomic View for RPS6KC1 Gene
Genes around RPS6KC1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q32.3 by Ensembl
- 1q32.3 by Entrez Gene
- 1q32.3 by HGNC
RPS6KC1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RPS6KC1 Gene
Proteins for RPS6KC1 Gene
-
Protein details for RPS6KC1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96S38-KS6C1_HUMAN
- Recommended name:
- Ribosomal protein S6 kinase delta-1
- Protein Accession:
- Q96S38
- B1APS8
- B3KVM4
- D3DTA4
- Q8TDD3
- Q9NSF4
- Q9UL66
Protein attributes for RPS6KC1 Gene
- Size:
- 1066 amino acids
- Molecular mass:
- 118682 Da
- Quaternary structure:
-
- Interacts with SPHK1 and phosphatidylinositol 3-phosphate.
- SequenceCaution:
-
- Sequence=CAB92850.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for RPS6KC1 Gene
Post-translational modifications for RPS6KC1 Gene
Other Protein References for RPS6KC1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- NP_001129610.1
- NP_001274147.1
- NP_001274148.1
- NP_001274149.1
- NP_001274150.1
- NP_001336575.1
- NP_001336576.1
- NP_001336577.1
- NP_001336578.1
- NP_001336579.1
- NP_001336580.1
- NP_001336581.1
- NP_001336582.1
- NP_001336583.1
- NP_001336586.1
- NP_001336587.1
- NP_001336588.1
- NP_001336589.1
- NP_001336590.1
- NP_001336591.1
- NP_001336592.1
- NP_001336593.1
- NP_001336594.1
- NP_001336595.1
- NP_001336596.1
- NP_001336597.1
- NP_001336598.1
- NP_001336599.1
- NP_001336600.1
- NP_001336601.1
- NP_036556.2
- XP_005273152.1
- XP_005273153.1
- XP_006711335.1
- XP_016856513.1
- XP_016856514.1
- XP_016856515.1
- XP_016856516.1
- XP_016856517.1
- XP_016856518.1
- XP_016856519.1
- XP_016856520.1
- XP_016856521.1
- XP_016856522.1
- XP_016856523.1
Antibody Products
-
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-
Abcam antibodies for RPS6KC1
- Invitrogen Antibodies for RPS6KC1
- antibodies-online Antibodies for RPS6KC1: See all 38
- Search GeneTex for Antibodies for RPS6KC1
Protein Products
-
OriGene Purified Proteins for RPS6KC1
- Search Origene for MassSpec and Protein Over-expression Lysates for RPS6KC1
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- antibodies-online Proteins for RPS6KC1: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for RPS6KC1
-
Abcam proteins for RPS6KC1
Assay Products
- antibodies-online Kits for RPS6KC1: See all 1
No data available for DME Specific Peptides for RPS6KC1 Gene
Domains & Families for RPS6KC1 Gene
Gene Families for RPS6KC1 Gene
Protein Domains for RPS6KC1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for RPS6KC1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q96S38UniProtKB/Swiss-Prot:
KS6C1_HUMAN :- The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site.
- Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily.
- Domain:
-
- The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site.
- Family:
-
- Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily.
Function for RPS6KC1 Gene
Molecular function for RPS6KC1 Gene
- GENATLAS Biochemistry:
- ribosomal protein S6 kinase,polypeptide 1,expressed highly in testis,skeletal muscle,brain and pancreas,not involved in vivo in the phosphorylation of RPS6,mediating protein synthesis initiation and elongation induced by hormones or growth factors,maybe playing an essentilal regulatory role in protein synthesis during cell proliferation
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + a protein = ADP + a phosphoprotein.
- UniProtKB/Swiss-Prot Function:
- May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.
Enzyme Numbers (IUBMB) for RPS6KC1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004672 | protein kinase activity | IEA | -- |
| GO:0004674 | protein serine/threonine kinase activity | TAS,IEA | -- |
| GO:0005515 | protein binding | IPI | 15750338 |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0016301 | kinase activity | IEA | -- |
Phenotypes for RPS6KC1 Gene
- GenomeRNAi human phenotypes for RPS6KC1:
-
- Lamellipodia cells
- Decreased NF-kappaB reporter expression
- Increased transferrin (TF) endocytosis
- Decreased shRNA abundance (Z-score < -2)
- Increased shRNA abundance (Z-score > 2)
- Decreased viability
- Decreased cell migration
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Decreased human cytomegalovirus (HCMV) strain AD169 replication
- Increased epidermal growth factor receptor (EGFR) surface abundance
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for RPS6KC1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RPS6KC1 gene
- Search ViGene Biosciences for RPS6KC1
CRISPR Products
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-
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- GenScript: Design CRISPR guide RNA sequences for RPS6KC1
miRNA for RPS6KC1 Gene
- miRTarBase miRNAs that target RPS6KC1
miRNA Products
- Search ViGene Biosciences for RPS6KC1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for RPS6KC1
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Clone Products
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- Addgene plasmids for RPS6KC1
- VectorBuilder custom plasmid, inducible vectors for RPS6KC1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RPS6KC1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for RPS6KC1
-
ViGene Biosciences adenoviral particle packaged cDNA for RPS6KC1 gene
-
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-
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No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RPS6KC1 Gene
Localization for RPS6KC1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RPS6KC1 Gene
- Cytoplasm. Membrane. Note=Also found in some small dot-like or ring-shaped early endosome structures.
| Compartment | Confidence |
|---|---|
| endosome | 5 |
| cytosol | 4 |
| nucleus | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005769 | early endosome | IDA | 15750338 |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for RPS6KC1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Nanog in Mammalian ESC Pluripotency | ||
| 2 | CNTF Signaling |
.50
|
|
Pathways by source for RPS6KC1 Gene
2 Qiagen pathways for RPS6KC1 Gene
Interacting Proteins for RPS6KC1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006468 | protein phosphorylation | IEA | -- |
| GO:0007165 | signal transduction | TAS | 10552933 |
| GO:0016310 | phosphorylation | IEA | -- |
No data available for SIGNOR curated interactions for RPS6KC1 Gene
Transcripts for RPS6KC1 Gene
mRNA/cDNA for RPS6KC1 Gene
- (45) REFSEQ mRNAs :
- (16) Additional mRNA sequences :
- (108) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RPS6KC1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for RPS6KC1
-
Santa Cruz Biotechnology (SCBT) CRISPR for RPS6KC1
- GenScript: Design CRISPR guide RNA sequences for RPS6KC1
miRNA Products
- Search ViGene Biosciences for RPS6KC1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for RPS6KC1
- Browse OriGene Inhibitory RNA Products For RPS6KC1
-
ViGene Biosciences ready-to-package AAV shRNAs for RPS6KC1 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for RPS6KC1
- VectorBuilder custom plasmid, inducible vectors for RPS6KC1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RPS6KC1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||
| SP4: |
Expression for RPS6KC1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
This gene is overexpressed in Adipocyte (57.5) and Monocytes (9.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RPS6KC1 Gene
NURSA nuclear receptor signaling pathways regulating expression of RPS6KC1 Gene:
RPS6KC1SOURCE GeneReport for Unigene cluster for RPS6KC1 Gene:
Hs.591416mRNA Expression by UniProt/SwissProt for RPS6KC1 Gene:
Q96S38-KS6C1_HUMAN
Tissue specificity:
Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.
Evidence on tissue expression from TISSUES for RPS6KC1 Gene
- Nervous system(4.7)
- Heart(4.6)
- Liver(4.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for RPS6KC1
-
OriGene qPCR primer pairs for RPS6KC1
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for RPS6KC1 Gene
Orthologs for RPS6KC1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RPS6KC1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | RPS6KC1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | RPS6KC1 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Rps6kc1 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | RPS6KC1 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Rps6kc1 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | RPS6KC1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | RPS6KC1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | RPS6KC1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | rps6kc1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | RPS6KC1 35 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | CG7156 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP001909 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | rskd-1 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for RPS6KC1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for RPS6KC1 Gene
Paralogs for RPS6KC1 Gene
(4) SIMAP similar genes for RPS6KC1 Gene using alignment to 3 proteins:
Variants for RPS6KC1 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_040652 | A lung neuroendocrine carcinoma sample | ||||
| VAR_040654 | An ovarian mucinous carcinoma sample | ||||
| VAR_040656 | A lung adenocarcinoma sample | ||||
| VAR_040657 | A breast infiltrating ductal carcinoma sample | ||||
| rs193921071 | Uncertain significance | 213,272,596(+) | ATCCA(C/T)TTTTT | intron-variant, reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv573n100 | CNV | gain | 25217958 |
| esv1004277 | CNV | gain | 20482838 |
| esv2666633 | CNV | deletion | 23128226 |
| esv2671923 | CNV | deletion | 23128226 |
| esv2675698 | CNV | deletion | 23128226 |
| esv275574 | CNV | gain+loss | 21479260 |
| esv28931 | CNV | loss | 19812545 |
| esv3546288 | CNV | deletion | 23714750 |
| esv3588764 | CNV | loss | 21293372 |
| esv3588765 | CNV | loss | 21293372 |
| nsv4476 | CNV | insertion | 18451855 |
| nsv508692 | CNV | deletion | 20534489 |
| nsv508693 | CNV | deletion | 20534489 |
| nsv549178 | CNV | loss | 21841781 |
| nsv826598 | CNV | loss | 20364138 |
Residual Variation Intolerance Score:
20.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.32;
62.98% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for RPS6KC1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPS6KC1 Gene
Disorders for RPS6KC1 Gene
Relevant External Links for RPS6KC1
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- RPS6KC1
No disorders were found for RPS6KC1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RPS6KC1 Gene
Publications for RPS6KC1 Gene
- Cloning, characterization, and chromosome mapping of RPS6KC1, a novel putative member of the ribosome protein S6 kinase family, to chromosome 12q12-q13.1. (PMID: 10552933) Zhang H. … Zhao S. (Genomics 1999) 2 3 4 64
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein. (PMID: 12077123) Hayashi S. … Nakamura S. (J. Biol. Chem. 2002) 3 4 64
Products for RPS6KC1 Gene
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- ViGene Biosciences lentiviral particle packaged cDNA for RPS6KC1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for RPS6KC1 gene
- Search ViGene Biosciences for RPS6KC1
- Search Santa Cruz Biotechnology (SCBT) for RPS6KC1 Antibodies
- Search Santa Cruz Biotechnology (SCBT) for RPS6KC1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RPS6KC1
- Horizon Cell Lines for RPS6KC1
- Cyagen custom Knockout/knockin (KOKI) mouse models for RPS6KC1
- VectorBuilder custom plasmid, inducible vectors for RPS6KC1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RPS6KC1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for RPS6KC1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer