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RPS5 Gene

protein-coding   GIFtS: 63
GCID: GC19P059295

Ribosomal Protein S5

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein S51 2
40S Ribosomal Protein S51 2
S52

External Ids:    HGNC: 104261   Entrez Gene: 61932   Ensembl: ENSG000000838457   OMIM: 6036305   UniProtKB: P467823   

Export aliases for RPS5 gene to outside databases

Previous GC identifers: GC19P059797 GC19P059352 GC19P063574 GC19P063590 GC19P059040 GC19P059053 GC19P055207 GC19P059076 GC19P059095 GC19P059106 GC19P059149 GC19P059205 GC19P059246


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPS5 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of
ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers
compared to adjacent normal tissues has been observed, although no correlation between the level of expression
and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are
multiple processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPS5 Gene:
RPS5 (ribosomal protein S5) is a protein-coding gene. Diseases associated with RPS5 include colorectal cancer, and influenza. GO annotations related to this gene include mRNA binding and RNA binding.

Gene Wiki entry for RPS5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NC_018930.2  NT_011109.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPS5 gene promoter:
         AhR   TBP   CUTL1   Arnt   E47   AREB6   STAT3   SEF-1 (1)   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS5 promoter sequence
   Search Chromatin IP Primers for RPS5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPS5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.4   Ensembl cytogenetic band:  19q13.43   HGNC cytogenetic band: 19q13.4

RPS5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS5 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P059295:  view genomic region     (about GC identifiers)

Start:
58,897,767 bp from pter      End:
58,906,173 bp from pter
Size:
8,407 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RS5_HUMAN, P46782 (See protein sequence)
Recommended Name: 40S ribosomal protein S5  
Size: 204 amino acids; 22876 Da
1 PDB 3D structure from and Proteopedia for RPS5:
3J3A (3D)    
Secondary accessions: B2R4T2 Q96BN0

Explore the universe of human proteins at neXtProt for RPS5: NX_P46782

Explore proteomics data for RPS5 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys18, Lys22, Lys47, Lys63, Lys167, Lys182
  • Modification sites at PhosphoSitePlus

  • See RPS5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001000.2  
    ENSEMBL proteins: 
     ENSP00000470114   ENSP00000471185   ENSP00000470660   ENSP00000471388   ENSP00000472985  
     ENSP00000196551  
    Reactome Protein details: P46782

    RPS5 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPS: S ribosomal proteins

    4 InterPro protein domains:
     IPR005716 Ribosomal_S5/S7_euk/arc
     IPR000235 Ribosomal_S5/S7
     IPR023798 Ribosomal_S7_dom
     IPR020606 Ribosomal_S7_CS

    Graphical View of Domain Structure for InterPro Entry P46782

    ProtoNet protein and cluster: P46782

    1 Blocks protein domain: IPB000235 Ribosomal protein S7

    UniProtKB/Swiss-Prot: RS5_HUMAN, P46782
    Similarity: Belongs to the ribosomal protein S7P family


    RPS5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPS5:
    40S ribosomal protein S5

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding NAS7772601
    GO:0003729mRNA binding IDA18464793
    GO:0003735structural constituent of ribosome IDA15883184
    GO:0044822poly(A) RNA binding IDA--
         
    RPS5 for ontologies           About GeneDecksing


    Phenotypes:
         9 GenomeRNAi human phenotypes for RPS5:
     Decreased cell number, increas  Decreased influenza A H1N1 (A/  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r 
     Decreased viability of wild-ty  Increased gamma-H2AX phosphory  Nuclear 40S maturation defects  Nucleolar pre-40S maturation d 
     S arrest 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPS5
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPS5

    miRNA
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    miRTarBase miRNAs that target RPS5:
    hsa-mir-324-3p (MIRT043015), hsa-mir-503-5p (MIRT041103), hsa-mir-132-3p (MIRT045846), hsa-mir-23a-3p (MIRT050401), hsa-mir-92a-3p (MIRT049510), hsa-mir-1301-3p (MIRT035988), hsa-mir-455-3p (MIRT037868)

    Block miRNA regulation of human, mouse, rat RPS5 using miScript Target Protectors
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    Sino Biological Human cDNA Clone for RPS5
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0015935small ribosomal subunit ----
    GO:0022627cytosolic small ribosomal subunit IDA15883184
    GO:0030529ribonucleoprotein complex IDA18809582
    GO:0070062extracellular vesicular exosome IDA--

    RPS5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPS5 About   (see all 6)  
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
    Translation initiation complex formation0.91
    Ribosomal scanning and start codon recognition0.91
    Formation of the ternary complex, and subsequently, the 43S complex0.91
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.90
    4Gene Expression
    Gene Expression0.40
    5Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS5
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS5
        Cytoplasmic Ribosomal Proteins


    Selected Reactome Pathways for RPS5 (see all 12)
        Peptide chain elongation
    Formation of the ternary complex, and subsequently, the 43S complex
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit


    1 Kegg Pathway  (Kegg details for RPS5):
        Ribosome


    RPS5 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPS5
    Interactions:

        Search GeneGlobe Interaction Network for RPS5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPS5 (P467822, 3 ENSP000001965514) via UniProtKB, MINT, STRING, and/or I2D (see all 634)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPS5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPS5 (RS5)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RPS5 gene: 
    NM_001009.3  

    Unigene Cluster for RPS5:

    Ribosomal protein S5
    Hs.378103  [show with all ESTs]
    Unigene Representative Sequence: BG165682
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000601521 ENST00000596314 ENST00000598098 ENST00000598495 ENST00000599909
    ENST00000598807 ENST00000596046 ENST00000599232 ENST00000196551(uc002qsn.3)

    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPS5
      QuantiTect SYBR Green Assays in human, mouse, rat RPS5
      QuantiFast Probe-based Assays in human, mouse, rat RPS5

    Additional mRNA sequence: 

    AB209803.1 AK223106.1 AK311938.1 BC015405.1 BC018151.1 BC018828.2 BC035830.1 U14970.1 

    Selected DOTS entries (see all 50):

    DT.100060249  DT.100709181  DT.100060251  DT.87017105  DT.91890461  DT.97870393  DT.100042463  DT.100851953 
    DT.102840970  DT.100709191  DT.97870395  DT.100709193  DT.121466589  DT.91927774  DT.95356807  DT.100033996 
    DT.100872459  DT.121403362  DT.121466554  DT.75191784  DT.92377009  DT.95356720  DT.100709175  DT.100709192 

    Selected AceView cDNA sequences (see all 2786):

    BQ424555 CA442349 BQ943142 BE378459 AA339853 BQ361134 BM008812 AA714201 
    BM693192 BQ362278 BM823607 BE797138 BM724564 BU538296 BQ424988 AA378352 
    AU107609 BQ445877 BM480106 BM810743 BU956462 AI094331 AA374233 BG386674 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RPS5    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7
    SP1:                                                        -               
    SP2:                          -                             -               
    SP3:                                                                        
    SP4:                                                                        
    SP5:                                                                        


    ECgene alternative splicing isoforms for RPS5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPS5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTTCGAGAT
    RPS5 Expression
    About this image


    RPS5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 23) fully expand
     
     Tonsil (Hematopoietic System)    fully expand to see all 3 entries
             tonsil ; non-germinal center cells   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Epithelial Cells (Uncategorized)
             tonsil ; squamous epithelial cells   
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    RPS5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPS5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.378103
        Custom PCR Arrays for RPS5
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS5 gene from Selected species (see all 28)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rps51 , 5 ribosomal protein S51, 5 90.52(n)1
    99.02(a)1
      7 (7.69 cM)5
    201031  NM_009095.21  NP_033121.21 
     129222905 
    lizard
    (Anolis carolinensis)
    Reptilia RPS56
    ribosomal protein S5
    99(a)
    1 ↔ 1
    2(189658291-189667266)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC644902 hypothetical protein MGC64490 81.11(n)    BC041523.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC059443.12   -- 84.29(n)   192297  BC059443.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpS53
    RpS5a1
    protein biosynthesis structural
    constituent of more3
    Ribosomal protein S5a1
    88(a)
    (best of 2)3
    77.5(n)1
    87.68(a)1
      327001  NM_078658.21  NP_523382.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rps-51 , 3 40S ribosomal protein S53
    rps-51
    86(a)3
    73.6(n)1
    86.8(a)1
      IV(11110391-11111219)3
    1780121  NM_069676.31  NP_502077.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPS5(YJR123W)4
    RPS51
    Protein component of the small (40S) ribosomal subunit, more4
    RPS51
    63.97(n)1
    71.21(a)1
      10(651901-652578)4
    8535871, 4  NP_012657.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RPS5B1 RPS5B 68.59(n)
    79.58(a)
      818304  NM_129283.3  NP_181264.1 
    rice
    (Oryza sativa)
    Liliopsida AK059558.12   -- 78(n)    AK059558.1 


    ENSEMBL Gene Tree for RPS5 (if available)
    TreeFam Gene Tree for RPS5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPS5 gene

    RPS5 for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for RPS5 (see all 8)
    PGOHUM00000245202 PGOHUM00000239068 PGOHUM00000239070 PGOHUM00000249721 PGOHUM00000235948


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPS5 (see all 169)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs37645361,2
    C,F,H--58896712(-) TGAGGG/AGCATG 1 -- us2k121Minor allele frequency- A:0.26EA NS NA WA 3970
    rs2020016601,2
    --58896919(+) GAGCT-/GTGACT 1 -- us2k10--------
    rs1174445351,2
    C,F--58897016(+) GTCAGG/TCAGTG 1 -- us2k11Minor allele frequency- T:0.02NA 120
    rs1140194951,2
    F--58897401(+) GGGCAC/GTCACT 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1885021461,2
    --58897451(+) AAGGCC/TCACAT 1 -- us2k10--------
    rs1930855501,2
    --58897541(+) CCTACC/TTGTTC 1 -- us2k10--------
    rs1857325591,2
    --58897599(+) TGCTGA/GCGGGA 1 -- us2k10--------
    rs1906411761,2
    --58897601(+) CTGGCA/G/TGGAAT 1 -- us2k10--------
    rs1385789621,2
    C--58898176(+) GGCGGC/TGGTGA 1 -- us2k10--------
    rs9759471,2
    C,F,A,H--58898193(-) GGAGTG/AAGGCC 1 -- us2k112Minor allele frequency- A:0.19NS EA NA WA 928

    HapMap Linkage Disequilibrium report for RPS5 (58897767 - 58906173 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for RPS5:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833887CNV Loss17160897
    nsv817878CNV Loss17921354
    nsv833888CNV Loss17160897
    dgv4030n71CNV Loss21882294
    nsv515731CNV Gain+Loss19592680
    essv17855CNV CNV17122850
    dgv1136e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603630    OMIM disorders: --

    11 diseases for RPS5:    
    About MalaCards
    colorectal cancer    influenza    hepatitis c virus    hepatitis c
    tonsillitis    hepatitis    hiv-1    thyroiditis
    malaria    cerebritis    prostatitis


    RPS5 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for RPS5 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    erythroleukemia 51.1 1 10821535 (1)


    Export disorders for RPS5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPS5 gene, integrated from 10 sources (see all 82):
    (articles sorted by number of sources associating them with RPS5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (Genome Res. 1998)
    2. Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs. (PubMed id 7772601)1, 2, 3 Frigerio J.-M.... Iovanna J.L. (Biochim. Biophys. Acta 1995)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (Genome Res. 2002)
    5. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (Eur. J. Biochem. 1996)
    6. [Mutual effect of human ribosomal proteins S5 and S16 on their binding with 18S rRNA fragment 1203-1236/1521-1698]. (PubMed id 19807034)1, 9 Ian'shina D.D....Karpova G.G. (Mol. Biol. (Mosk.) 2009)
    7. Roles of the negatively charged N-terminal extension of Saccharomyces cerevisiae ribosomal protein S5 revealed by characterization of a yeast strain containing human ribosomal protein S5. (PubMed id 17901157)1, 9 Galkin O....Komar A.A. (RNA 2007)
    8. A Proteomics Strategy for the Identification of FAT10-Modified Sites by Mass Spectrometry. (PubMed id 23862649)1 Leng L....Wang J. (J. Proteome Res. 2014)
    9. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    10. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6193 HGNC: 10426 AceView: RPS5andZNF584 Ensembl:ENSG00000083845 euGenes: HUgn6193
    ECgene: RPS5 Kegg: 6193 H-InvDB: RPS5

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RPS5 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RPS5 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPS5 gene:
    Search GeneIP for patents involving RPS5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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