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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPS5 Gene

protein-coding   GIFtS: 60
GCID: GC19P059205

ribosomal protein S5
 Explore 4 diseases affiliated with
RPS5 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RPS5    

Aliases
for RPS5 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Ribosomal Protein S51 2
S51 2
40S Ribosomal Protein S52

External Ids:    HGNC: 104261   Entrez Gene: 61932   Ensembl: ENSG000000838457   OMIM: 6036305   UniProtKB: P467823   

Export aliases for RPS5 gene to outside databases

Previous GC identifers: GC19P059797 GC19P059352 GC19P063574 GC19P063590 GC19P059040 GC19P059053 GC19P055207 GC19P059076 GC19P059095 GC19P059106 GC19P059149


Summaries
for RPS5 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RPS5:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene
encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal
proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent
normal tissues has been observed, although no correlation between the level of expression and the severity of the
disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes
of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

Gene Wiki entry for RPS5


Genomic Views
for RPS5 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPS5 gene promoter:
         AhR   TBP   CUTL1   Arnt   E47   AREB6   STAT3   SEF-1 (1)   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RPS5 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPS5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.4   Ensembl cytogenetic band:  19q13.43   HGNC cytogenetic band: 19q13.4

RPS5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS5 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P059205:  view genomic region     (about GC identifiers)

Start:
 58,898,636 bp from pter      End:
 58,906,171 bp from pter
Size:
 7,536 bases      Orientation:
 plus strand

Proteins
for RPS5 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RS5_HUMAN, P46782 (See protein sequence)
Recommended Name: 40S ribosomal protein S5  
Size: 204 amino acids; 22876 Da
Secondary accessions: B2R4T2 Q96BN0

Explore the universe of human proteins at neXtProt for RPS5: NX_P46782

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P46782

    • RPS5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001000.2  
    ENSEMBL proteins: 
     ENSP00000196551  
    Reactome Protein details: P46782
    Human Recombinant Protein Products: 
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    Novus Biologicals RPS5 Proteins
    Novus Biologicals RPS5 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RPS5

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0022627cytosolic small ribosomal subunit IDA8706699
    GO:0030529ribonucleoprotein complex IDA18809582


    RPS5 for ontologies           About GeneDecksing



    RPS5 Antibody Products: 
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    Uscn ELISAs and CLIAs for RPS5

    Protein Domains /
    Families
    for RPS5 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RPS5 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR005716 Ribosomal_S5/S7_euk/arc
     IPR000235 Ribosomal_S5/S7
     IPR023798 Ribosomal_S7_dom
     IPR020606 Ribosomal_S7_CS

    Graphical View of Domain Structure for InterPro Entry P46782

    ProtoNet protein and cluster: P46782

    1 Blocks protein family: IPB000235 Ribosomal protein S7

    UniProtKB/Swiss-Prot: RS5_HUMAN, P46782
    Similarity: Belongs to the ribosomal protein S7P family


    Function
    for RPS5 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
         Genatlas biochemistry entry for RPS5:
    40S ribosomal protein S5

    miRNA
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS5 (see all 7)
    OriGene shRNA RFP: RPS5
    OriGene siRNA: RPS5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS5

    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPS5 (see all 3)
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    GenScript: all cDNA clones in your preferred vector: RPS5 (NM_001009)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS5 

    Cell Line
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    Search LifeMap BioReagents cell lines for RPS5

    In Situ Assay
    Products:       
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS5

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding NAS7772601
    GO:0003729mRNA binding IDA18464793
    GO:0003735structural constituent of ribosome IDA15883184


    RPS5 for ontologies           About GeneDecksing


    9 GenomeRNAi human phenotypes for RPS5:
     Decreased cell number, increas  Decreased influenza A H1N1 (A/  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r 
     Decreased viability of wild-ty  Increased gamma-H2AX phosphory  Nuclear 40S maturation defects  Nucleolar pre-40S maturation d 
     S arrest 


    Pathways & Interactions
    for RPS5 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    		Viral Protein Synthesis1.00
    		Cytoplasmic Ribosomal Proteins0.86
    		Viral mRNA Translation1.00
    		CFTR translational fidelity (class I mutations)0.83
    		Influenza Viral RNA Transcription and Replication1.00
    		SMG6 Cleaves mRNA with Premature Termination Codon0.80
    		Synthesis of nascent polypeptide containing signal sequence1.00
    		L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Translation initiation complex formation
    		Translation initiation complex formation1.00
    		Ribosomal scanning and start codon recognition0.96
    		Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.98
    		Formation of the ternary complex, and subsequently, the 43S complex0.87
    3Metabolism of mRNA
    		Metabolism of mRNA1.00
    		Metabolism of RNA0.92
    4Disease
    		Disease1.00
    5Generic Transcription Pathway
    		Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS5
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS5 
        Cytoplasmic Ribosomal Proteins

    5/32        Reactome Pathways for RPS5 (see all 32)
        Formation of a pool of free 40S subunits
    Synthesis of PB1-F2
    SMG6 Cleaves mRNA with Premature Termination Codon
    Influenza Life Cycle
    Viral mRNA Translation


    1         Kegg Pathway  (Kegg details for RPS5):
        Ribosome


    RPS5 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPS5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/532 Interacting proteins for RPS5 (P467822, 3 ENSP000001965514) via UniProtKB, MINT, STRING, and/or I2D (see all 532)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--


    RPS5 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RPS5 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPS5
    Search CenterWatch for drugs/clinical trials and news about RPS5 / RS5 

    Transcripts
    for RPS5 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RPS5 gene: 
    NM_001009.3  

    Unigene Cluster for RPS5:

    Ribosomal protein S5
    Hs.378103  [show with all ESTs]
    Unigene Representative Sequence: BG165682
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000196551(uc002qsn.3)

    miRNA
    Products:             		 OriGene 3'-UTR Clone: RPS5
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPS5
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS5 (see all 7)
    OriGene shRNA RFP: RPS5
    OriGene siRNA: RPS5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS5
    Clone
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    GenScript: all cDNA clones in your preferred vector: RPS5 (NM_001009)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS5 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RPS5
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS5

    Additional cDNA sequence: 

    AB209803.1 AK223106.1 AK311938.1 BC015405.1 BC018151.1 BC018828.2 BC035830.1 U14970.1 

    24/50 DOTS entries (see all 50):

    DT.100060249  DT.100709181  DT.100060251  DT.87017105  DT.97870393  DT.91890461  DT.100042463  DT.100851953 
    DT.102840970  DT.100709191  DT.97870395  DT.100709193  DT.121466589  DT.91927774  DT.95356807  DT.100033996 
    DT.100872459  DT.121403362  DT.121466554  DT.75191784  DT.92377009  DT.95356720  DT.100709175  DT.100709192 

    24/2786 AceView cDNA sequences (see all 2786):

    AA860864 BE795762 BE263684 CN484759 BF036858 BM708256 BG036658 BG490412 
    BG874932 BI335045 AJ713781 BM843288 BQ064878 BM564925 BM852547 BX333264 
    BE796943 BM994929 BQ229635 BU527670 BI227108 AW405353 BE409451 BE395653 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RPS5    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7
    SP1:                                                        -               
    SP2:                          -                             -               
    SP3:                                                                        
    SP4:                                                                        
    SP5:                                                                        


    ECgene alternative splicing isoforms for RPS5

    Expression
    for RPS5 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPS5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCTTCGAGAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    RPS5 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Endoderm-like cells (Generation of hepato...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RPS5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPS5

    SOURCE GeneReport for Unigene cluster: Hs.378103
        SABiosciences Custom PCR Arrays for RPS5
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS5
    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS5

    Orthologs
    for RPS5 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS5 gene from 9/39 species (see all 39)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Rps51 , 5 ribosomal protein S51, 5 90.52(n)1
    99.02(a)1    		   7 (7.69 cM)5
    201031  NM_009095.21  NP_033121.21 
     129222905 
    lizard
    (Anolis carolinensis)    		 Reptilia RPS56
    		 --
    		 99(a)
    		 1 ↔ 1
    		 2(189658292-189662572)
    African clawed frog
    (Xenopus laevis)    		 Amphibia MGC644902 hypothetical protein MGC64490 81.11(n)    BC041523.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii BC059443.12   -- 84.29(n)   192297  BC059443.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta RpS53
    RpS5a1    		 protein biosynthesis structural constituent
    of more3
    Ribosomal protein S5a1    		 88(a)
    (best of 2)3
    78.17(n)1
    88.5(a)1    		   327001  NM_078658.21  NP_523382.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea rps-51 , 3 40S ribosomal protein S53
    Protein RPS-51    		 86(a)3
    73.6(n)1
    86.8(a)1    		   IV(11110391-11111219)3
    1780121  NM_069676.21  NP_502077.11 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes RPS5(YJR123W)4
    RPS51    		 Protein component of the small (40S) ribosomal subunit, more4
    Rps5p1    		 63.97(n)1
    71.21(a)1    		   10(651901-652578)4
    8535871, 4  NP_012657.11, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons RPS5B1 40S ribosomal protein S5-1 68.59(n)
    79.58(a)    		   818304  NM_001036425.2  NP_001031502.1 
    rice
    (Oryza sativa)    		 Liliopsida AK059558.12   -- 78(n)    AK059558.1 


    ENSEMBL Gene Tree for RPS5 (if available)
    TreeFam Gene Tree for RPS5 (if available) 

    Paralogs
    for RPS5 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPS5 gene

    RPS5 for paralogs           About GeneDecksing


    5/8 Pseudogenes.org Pseudogenes for RPS5 (see all 8)
    PGOHUM00000245202 PGOHUM00000239068 PGOHUM00000239070 PGOHUM00000249721 PGOHUM00000235948


    Genomic Variants
    for RPS5 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/221 NCBI SNPs in RPS5 are shown (see all 221)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs37645361,2
    		C,F,H,--58896712(-) TGAGGG/AGCATG 1 -- us2k121Minor allele frequency- A:0.26EA NS NA WA 3970
    rs2020016601,2
    		--58896919(+) GAGCT-/GTGACT 1 -- us2k10--------
    rs1174445351,2
    		F,--58897016(+) GTCAGG/TCAGTG 1 -- us2k11Minor allele frequency- T:0.02NA 120
    rs1140194951,2
    		F,--58897401(+) GGGCAC/GTCACT 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1885021461,2
    		--58897451(+) AAGGCC/TCACAT 1 -- us2k10--------
    rs1930855501,2
    		--58897541(+) CCTACC/TTGTTC 1 -- us2k10--------
    rs1857325591,2
    		--58897599(+) TGCTGA/GCGGGA 1 -- us2k10--------
    rs1906411761,2
    		--58897601(+) CTGGCA/G/TGGAAT 1 -- us2k10--------
    rs1146678531,2
    		F,--58897638(+) TTCCAT/ACCCTC 2 -- ds5001 us2k11Minor allele frequency- A:0.12WA 118
    rs37949741,2
    		C,F,H,--58897652(-) CCAAAG/AGTTGA 2 -- ds5001 us2k126Minor allele frequency- A:0.18EA NS NA WA 4412

    HapMap Linkage Disequilibrium report for RPS5 (58898636 - 58906171 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for RPS5
         7 CNVs: 3204 50240 50238 50237 10572 50239 5119

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    Disorders / Diseases
    for RPS5 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RPS5 for disorders           About GeneDecksing

    OMIM gene information: 603630    OMIM disorders: --

    4 diseases for RPS5:    About MalaCards
    colorectal cancer    hepatitis c    hepatitis    malaria

    1 Novoseek disease relationship for RPS5 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    erythroleukemia 51.1 1 10821535 (1)


    Export disorders for RPS5 gene to outside databases

    Publications
    for RPS5 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPS5 gene, integrated from 9 sources (see all 65):
    (articles sorted by number of sources associating them with RPS5)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (1998)
    2. Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs. (PubMed id 7772601)1, 2, 3 Frigerio J.-M.... Iovanna J.L. (1995)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (2002)
    5. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (1996)
    6. [Mutual effect of human ribosomal proteins S5 and S16 on their binding with 18S rRNA fragment 1203-1236/1521-1698] (PubMed id 19807034)1, 9 Ian'shina D.D....Karpova G.G. (2009)
    7. Roles of the negatively charged N-terminal extension of Saccharomyces cerevisiae ribosomal protein S5 revealed by characterization of a yeast strain containing human ribosomal protein S5. (PubMed id 17901157)1, 9 Galkin O....Komar A.A. (2007)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    10. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)

    External Searches for RPS5 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing RPS5 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6193 HGNC: 10426 AceView: RPS5andZNF584 Ensembl:ENSG00000083845 euGenes: HUgn6193
    ECgene: RPS5 Kegg: 6193 H-InvDB: RPS5

    Other Databases showing RPS5 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RPS5 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPS5 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RPS5 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for RPS5 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RPS5 gene:
    Search GeneIP for patents involving RPS5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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