Aliases for RPS4Y1 Gene
External Ids for RPS4Y1 Gene
Previous HGNC Symbols for RPS4Y1 Gene
Previous GeneCards Identifiers for RPS4Y1 Gene
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
GeneCards Summary for RPS4Y1 Gene
RPS4Y1 (Ribosomal Protein S4, Y-Linked 1) is a Protein Coding gene. Diseases associated with RPS4Y1 include Turner Syndrome. Among its related pathways are Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S and Metabolism. GO annotations related to this gene include RNA binding and rRNA binding. An important paralog of this gene is RPS4Y2.