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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPS4Y1 Gene

protein-coding   GIFtS: 57
GCID: GC0YP002709

Ribosomal Protein S4, Y-Linked 1

(Previous names: ribosomal protein S4, Y-linked)
(Previous symbol: RPS4Y)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ribosomal Protein S4, Y-Linked 11 2     Ribosomal Protein S4, Y-Linked1
RPS4Y1 2 3     40S Ribosomal Protein S4, Y2
Ribosomal Protein S4Y1 2     40S Ribosomal Protein S4, Y Isoform 12
40S Ribosomal Protein S41     S42
Y1     

External Ids:    HGNC: 104251   Entrez Gene: 61922   Ensembl: ENSG000001298247   OMIM: 4700005   UniProtKB: P220903   

Export aliases for RPS4Y1 gene to outside databases

Previous GC identifers: GC0YP002356 GC0YP002753 GC0YP002769 GC0YP000062


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RPS4Y1 Gene:
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S
subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct
proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the
only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4,
X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent.
Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that
haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is
controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of
this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPS4Y1 Gene: 
RPS4Y1 (ribosomal protein S4, Y-linked 1) is a protein-coding gene. Diseases associated with RPS4Y1 include turner syndrome, and gonadoblastoma, and among its related super-pathways are Eukaryotic Translation Initiation and Formation of the ternary complex, and subsequently, the 43S complex. GO annotations related to this gene include RNA binding and rRNA binding. An important paralog of this gene is RPS4Y2.

Gene Wiki entry for RPS4Y1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000024.9  NT_011896.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPS4Y1 gene promoter:
         Elk-1   Pax-6   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   Tal-1beta   Evi-1   GATA-1   STAT3   ITF-2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS4Y1 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPS4Y1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS4Y1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Yp11.3   Ensembl cytogenetic band:  Yp11.31   HGNC cytogenetic band: Yp11.3

RPS4Y1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS4Y1 gene location

GeneLoc information about chromosome Y         GeneLoc Exon Structure

GeneLoc location for GC0YP002709:  view genomic region     (about GC identifiers)

Start:
2,709,527 bp from pter      End:
2,735,309 bp from pter
Size:
25,783 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RS4Y1_HUMAN, P22090 (See protein sequence)
Recommended Name: 40S ribosomal protein S4, Y isoform 1  
Size: 263 amino acids; 29456 Da
Secondary accessions: A8K9V4

Explore the universe of human proteins at neXtProt for RPS4Y1: NX_P22090

Explore proteomics data for RPS4Y1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P22090

  • RPS4Y1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RPS4Y1 Protein Expression
    REFSEQ proteins: NP_000999.1  
    ENSEMBL proteins: 
     ENSP00000250784   ENSP00000415317  
    Reactome Protein details: P22090
    Human Recombinant Protein Products for RPS4Y1: 
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RPS4Y1 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0005844polysome IDA8139551
    GO:0022627cytosolic small ribosomal subunit NAS8358435

    RPS4Y1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RPS: S ribosomal proteins

    5/6 InterPro protein domains (see all 6):
     IPR013845 Ribosomal_S4e_central_region
     IPR002942 S4_RNA-bd
     IPR013843 Ribosomal_S4e_N
     IPR000876 Ribosomal_S4e
     IPR018199 Ribosomal_S4e_N_CS

    Graphical View of Domain Structure for InterPro Entry P22090

    ProtoNet protein and cluster: P22090

    2 Blocks protein domains:
    IPB000876 Ribosomal protein S4E
    IPB002942 RNA-binding S4


    UniProtKB/Swiss-Prot: RS4Y1_HUMAN, P22090
    Similarity: Belongs to the ribosomal protein S4e family
    Similarity: Contains 1 S4 RNA-binding domain


    RPS4Y1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS2124517
    GO:0003735structural constituent of ribosome IMP8358435
    GO:0019843rRNA binding IEA--
         
    RPS4Y1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for RPS4Y1:
     Increased cell death HMECs cel  Increased cell death in breast 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RPS4Y1 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPS4Y1 
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    Gene Editing
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    Clone
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RPS4Y1 About   (see all 6)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Viral mRNA Translation
    Influenza Life Cycle0.95
    3' -UTR-mediated translational regulation0.93
    Influenza Infection0.95
    L13a-mediated translational silencing of Ceruloplasmin expression0.93
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Formation of a pool of free 40S subunits0.90
    Eukaryotic Translation Termination0.94
    Nonsense-Mediated Decay0.84
    2Translation initiation complex formation
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.95
    Formation of the ternary complex, and subsequently, the 43S complex0.87
    Ribosomal scanning and start codon recognition0.95
    Translation initiation complex formation0.87
    3Metabolism of mRNA
    Metabolism of mRNA0.92
    Metabolism of RNA0.92
    4Generic Transcription Pathway
    Gene Expression0.47
    5Asparagine N-linked glycosylation
    Metabolism of proteins0.35

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS4Y1
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS4Y1
        Cytoplasmic Ribosomal Proteins

    5/27        Reactome Pathways for RPS4Y1 (see all 27)
        Formation of the ternary complex, and subsequently, the 43S complex
    Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane


    1         Kegg Pathway  (Kegg details for RPS4Y1):
        Ribosome


    RPS4Y1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPS4Y1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/106 Interacting proteins for RPS4Y1 (P220903 ENSP000002507844) via UniProtKB, MINT, STRING, and/or I2D (see all 106)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALM1P621583I2D: score=1 
    CALM2P621583I2D: score=1 
    CALM3P621583I2D: score=1 
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    RPS13ENSP000002281404STRING: ENSP00000228140
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPS4Y1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPS4Y1 (RS4Y1)

    Search CenterWatch for drugs/clinical trials and news about RPS4Y1 / RS4Y1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPS4Y1 gene: 
    NM_001008.3  

    Unigene Cluster for RPS4Y1:

    Ribosomal protein S4, Y-linked 1
    Hs.282376  [show with all ESTs]
    Unigene Representative Sequence: BQ050176
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000250784(uc004fqe.1 uc004fqi.3) ENST00000430575(uc004fqf.1)
    ENST00000477725
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    Clone
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPS4Y1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS4Y1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS4Y1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS4Y1

    Additional mRNA sequence: 

    AK222594.1 AK292819.1 BC010286.1 BC100905.2 BC100906.1 M58459.1 Z48516.1 

    20 DOTS entries:

    DT.100827736  DT.75167842  DT.120652327  DT.91777953  DT.100827733  DT.120652318  DT.120652320  DT.91855742 
    DT.99947498  DT.91777975  DT.91843605  DT.91787021  DT.91777983  DT.95290574  DT.100827739  DT.101987268 
    DT.120652344  DT.100731609  DT.120653212  DT.91747179 

    24/558 AceView cDNA sequences (see all 558):

    BQ302163 BQ374912 BM973258 BQ950830 BF092414 CB123821 BM907692 BM831452 
    BE018626 AI815615 AW382361 AA352870 CR591112 AV649174 BG896265 BQ302271 
    BQ925129 BF888335 BU730658 AW239555 BM834721 BM834685 AA180328 NM_001008 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPS4Y1 expression in normal human tissues (normalized intensities)      RPS4Y1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGAAGGATGC
    RPS4Y1 Expression
    About this image


    RPS4Y1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/25 selected tissues (see all 25) fully expand
     
     Fibroblast
             Human Prostate Fibroblasts (HPrF)   
     
     Smooth Muscle (Muscoskeletal System)    fully expand to see all 6 entries
             Human umbilical Smooth Muscle (HUSM)   
     
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 4 entries
             Human umbilical Smooth Muscle (HUSM)   
     
     Dermis (Uncategorized)    fully expand to see all 4 entries
             Human Hair Outer Root Sheath Cells (HHORSC)   
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Human Brain Vascular Pericyte (HBVP)   

    See RPS4Y1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPS4Y1

    SOURCE GeneReport for Unigene cluster: Hs.282376
        SABiosciences Custom PCR Arrays for RPS4Y1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS4Y1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS4Y1 gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves RPS46
    40S ribosomal protein S4
    94(a)
    possible ortholog
    4(1867724-1871061)
    lizard
    (Anolis carolinensis)
    Reptilia RPS4X6
    ribosomal protein S4, X-linked
    94(a)
    possible ortholog
    GL343686.1(237404-240652)
    zebrafish
    (Danio rerio)
    Actinopterygii rps4x6
    ribosomal protein S4, X-linked
    88(a)
    1 → many
    7(53088995-53094879)
    fruit fly
    (Drosophila melanogaster)
    Insecta RpS46
    Ribosomal protein S4
    74(a)
    1 → many
    3L(13034856-13037005)
    worm
    (Caenorhabditis elegans)
    Secernentea rps-46
    40S ribosomal protein S4
    63(a)
    1 → many
    IV(7083694-7084684)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPS4B6
    RPS4A6
    Protein component of the small (40S) ribosomal sub...
    Protein component of the small (40S) ribosomal sub...
    70(a)
    70(a)
    many ↔ many
    many ↔ many
    VIII(504476-505530)
    X(702027-703068)
    Alicante grape
    (Vitis vinifera)
    eudicotyledons Vvi.28192 Vitis vinifera transcribed sequence with strong similarity more 74.52(n)    CA818207.1 
    rice
    (Oryza sativa)
    Liliopsida Os.122382 Oryza sativa SS620 mRNA for scar protein, partial cds 75.85(n)    AK061776.1 
            Species with no ortholog for RPS4Y1

    ENSEMBL Gene Tree for RPS4Y1 (if available)
    TreeFam Gene Tree for RPS4Y1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPS4Y1 gene
    RPS4Y22  RPS4X2  
    3 SIMAP similar genes for RPS4Y1 using alignment to 4 protein entries:     RS4Y1_HUMAN (see all proteins):
    RPS4Y2    RPS4X    RPS4XP21

    RPS4Y1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for RPS4Y1
    PGOHUM00000248935 PGOHUM00000247432


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/128 SNPs in RPS4Y1 are shown (see all 128)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr Y posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs736251001,2
    C--2707859(+) TCCATC/GTGCAC 1 -- us2k12Minor allele frequency- G:0.00WA CSA 3
    rs726253681,2
    C--2710154(+) TGAGGA/GCATTT 1 -- int10--------
    rs344027621,2
    C--2710309(+) TGTGGT/GTTTTT 1 -- int12Minor allele frequency- G:0.02MN NA 48
    rs1128875921,2
    C--2711408(+) AGAGAG/CAAAGC 1 -- int11Minor allele frequency- C:0.00CSA 1
    rs753512251,2
    C--2719706(+) TGTTAA/TATCAT 1 -- int10--------
    rs775182941,2
    C--2722005(+) AGTAGC/GTGGGA 1 -- int10--------
    rs133051961,2
    C--2722413(+) CCAGAA/GGGTTC 1 -- int10--------
    rs20756401,2
    C,F,O,A,H--2722506(+) TTAATA/GTAGTT 1 -- int112Minor allele frequency- G:0.43NA EA NS WA CSA 475
    rs3723847371,2
    C--2722516(+) TTTTCC/TAAGAG 1 -- int10--------
    rs115383081,2
    C--2722707(+) CTCATG/CATGCT 2 /H /D mis1 ese31Minor allele frequency- C:0.00NA 2

    HapMap Linkage Disequilibrium report for RPS4Y1 (2709527 - 2735309 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RPS4Y1: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RPS4Y1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 470000    OMIM disorders: --

    4 diseases for RPS4Y1:    About MalaCards
    turner syndrome    gonadoblastoma    azoospermia    influenza

    2 diseases from the University of Copenhagen DISEASES database for RPS4Y1:
    Turner syndrome     Gonadoblastoma

    RPS4Y1 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for RPS4Y1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    turners syndrome 82 1 2124517 (1)


    Export disorders for RPS4Y1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPS4Y1 gene, integrated from 9 sources (see all 37):
    (articles sorted by number of sources associating them with RPS4Y1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome. (PubMed id 2124517)1, 2, 9 Fisher E.M.C.... Page D.C. (1990)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes. (PubMed id 8139551)1, 9 Zinn A.R....Page D.C. (1994)
    4. Relationship between the monosomy X phenotype and Y-linked ribosomal protein S4 (Rps4) in several species of mammals: a molecular evolutionary analysis of Rps4 homologs. (PubMed id 8808278)1, 9 Omoe K. and Endo A. (1996)
    5. Functional equivalence of human X- and Y-encoded isoforms of ribosomal protein S4 consistent with a role in Turner syndrome. (PubMed id 8358435)1, 9 Watanabe M....Nishimoto T. (1993)
    6. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....Yanez-Mo M. (2013)
    7. Isolation of human CD4/CD8 double-positive, graft-vers us-host disease-protective, minor histocompatibility antigen-specific regulatory T cells and of a novel HLA-DR7-restricted HY-specific CD4 clone. (PubMed id 23225889)1 Eljaafari A....Scott D. (2013)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction. (PubMed id 22708584)1 Ye J....Madden T.L. (2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6192 HGNC: 10425 AceView: RPS4Y1 Ensembl:ENSG00000129824 euGenes: HUgn6192
    ECgene: RPS4Y1 Kegg: 6192 H-InvDB: RPS4Y1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPS4Y1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPS4Y1 gene:
    Search GeneIP for patents involving RPS4Y1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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