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Aliases for RPS29 Gene

Aliases for RPS29 Gene

  • Ribosomal Protein S29 2 3
  • 40S Ribosomal Protein S29 3
  • DBA13 3
  • S29 3

External Ids for RPS29 Gene

Previous GeneCards Identifiers for RPS29 Gene

  • GC14M047365
  • GC14M043840
  • GC14M048034
  • GC14M048040
  • GC14M049114
  • GC14M049120
  • GC14M049119
  • GC14M050043
  • GC14M030161

Summaries for RPS29 Gene

Entrez Gene Summary for RPS29 Gene

  • Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit and a member of the S14P family of ribosomal proteins. The protein, which contains a C2-C2 zinc finger-like domain that can bind to zinc, can enhance the tumor suppressor activity of Ras-related protein 1A (KREV1). It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]

GeneCards Summary for RPS29 Gene

RPS29 (Ribosomal Protein S29) is a Protein Coding gene. Diseases associated with RPS29 include diamond-blackfan anemia 13 and diamond-blackfan anemia. Among its related pathways are Disease and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include structural constituent of ribosome.

Gene Wiki entry for RPS29 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPS29 Gene

Genomics for RPS29 Gene

Regulatory Elements for RPS29 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for RPS29 Gene

49,570,984 bp from pter
49,599,164 bp from pter
28,181 bases
Minus strand

Genomic View for RPS29 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RPS29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPS29 Gene

Proteins for RPS29 Gene

  • Protein details for RPS29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    40S ribosomal protein S29
    Protein Accession:
    Secondary Accessions:
    • A8MZ73
    • P30054

    Protein attributes for RPS29 Gene

    56 amino acids
    Molecular mass:
    6677 Da
    Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.;
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RPS29 Gene

    Alternative splice isoforms for RPS29 Gene


neXtProt entry for RPS29 Gene

Proteomics data for RPS29 Gene at MOPED

Post-translational modifications for RPS29 Gene

  • Ubiquitination at Lys33 and Lys48
  • Modification sites at PhosphoSitePlus

Other Protein References for RPS29 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for RPS29 Gene

Domains for RPS29 Gene

Gene Families for RPS29 Gene

Protein Domains for RPS29 Gene


Suggested Antigen Peptide Sequences for RPS29 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ribosomal protein S14P family.
  • Belongs to the ribosomal protein S14P family.
genes like me logo Genes that share domains with RPS29: view

Function for RPS29 Gene

Molecular function for RPS29 Gene

GENATLAS Biochemistry:
40S ribosomal protein S29

Gene Ontology (GO) - Molecular Function for RPS29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003735 structural constituent of ribosome IDA 15883184
GO:0008270 zinc ion binding IDA 8781548
genes like me logo Genes that share ontologies with RPS29: view
genes like me logo Genes that share phenotypes with RPS29: view

miRNA for RPS29 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RPS29

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for RPS29 Gene

Localization for RPS29 Gene

Subcellular locations from

Jensen Localization Image for RPS29 Gene COMPARTMENTS Subcellular localization image for RPS29 gene
Compartment Confidence
cytosol 5
extracellular 2
mitochondrion 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for RPS29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005737 cytoplasm IDA --
GO:0005829 cytosol TAS --
GO:0005840 ribosome --
GO:0005925 focal adhesion IDA 21423176
genes like me logo Genes that share ontologies with RPS29: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RPS29 Gene

Pathways for RPS29 Gene

SuperPathways for RPS29 Gene

Superpath Contained pathways
1 Influenza Viral RNA Transcription and Replication
2 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
3 CFTR translational fidelity (class I mutations)
4 Disease
5 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
genes like me logo Genes that share pathways with RPS29: view

Pathways by source for RPS29 Gene

1 KEGG pathway for RPS29 Gene
1 GeneGo (Thomson Reuters) pathway for RPS29 Gene

Gene Ontology (GO) - Biological Process for RPS29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS --
GO:0006412 translation TAS --
GO:0006413 translational initiation TAS --
GO:0006414 translational elongation TAS --
GO:0006415 translational termination TAS --
genes like me logo Genes that share ontologies with RPS29: view

Transcripts for RPS29 Gene

Unigene Clusters for RPS29 Gene

Ribosomal protein S29:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RPS29

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RPS29 Gene

No ASD Table

Relevant External Links for RPS29 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RPS29 Gene

mRNA expression in normal human tissues for RPS29 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for RPS29 Gene

This gene is overexpressed in Tlymphocyte (9.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RPS29 Gene

SOURCE GeneReport for Unigene cluster for RPS29 Gene Hs.156367

genes like me logo Genes that share expressions with RPS29: view

Expression partners for RPS29 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RPS29 Gene

Orthologs for RPS29 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RPS29 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RPS29 35
  • 91.07 (n)
  • 98.21 (a)
RPS29 36
  • 96 (a)
(Canis familiaris)
Mammalia RPS29 35
  • 89.29 (n)
  • 98.21 (a)
(Mus musculus)
Mammalia Rps29 35
  • 85.71 (n)
  • 98.21 (a)
Rps29 16
Gm10126 36
  • 85 (a)
Rps29 36
  • 96 (a)
(Pan troglodytes)
Mammalia RPS29 35
  • 98.99 (n)
  • 100 (a)
RPS29 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Rps29 35
  • 86.9 (n)
  • 98.21 (a)
(Monodelphis domestica)
Mammalia RPS29 36
  • 96 (a)
(Gallus gallus)
Aves RPS29 35
  • 80.95 (n)
  • 98.21 (a)
RPS29 36
  • 90 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rps29 35
  • 80.95 (n)
  • 98.21 (a)
(Danio rerio)
Actinopterygii wufa11f02 35
rps29 36
  • 93 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.8386 35
fruit fly
(Drosophila melanogaster)
Insecta RpS29 36
  • 75 (a)
(Caenorhabditis elegans)
Secernentea rps-29 36
  • 71 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPS29A 36
  • 64 (a)
RPS29B 36
  • 63 (a)
RPS29A 38
(Triticum aestivum)
Liliopsida Ta.17501 35
Species with no ortholog for RPS29:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for RPS29 Gene

Gene Tree for RPS29 (if available)
Gene Tree for RPS29 (if available)

Paralogs for RPS29 Gene

genes like me logo Genes that share paralogs with RPS29: view

No data available for Paralogs for RPS29 Gene

Variants for RPS29 Gene

Sequence variations from dbSNP and Humsavar for RPS29 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs578087562 -- 49,578,739(+) TATTT(G/T)TAACA intron-variant
rs578053260 -- 49,584,095(+) TCCCA(C/T)CTCAA intron-variant
rs577955037 -- 49,577,131(+) AGCCA(C/G)TTGGG utr-variant-3-prime
rs577814270 -- 49,576,715(+) GTGGG(A/C)GATAA utr-variant-3-prime
rs577746576 -- 49,580,430(+) CACCA(A/T)CTTTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RPS29 Gene

Variant ID Type Subtype PubMed ID
esv28926 CNV Gain+Loss 19812545

Relevant External Links for RPS29 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPS29 Gene

Disorders for RPS29 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for RPS29 Gene in MalaCards »

(2) Diseases for RPS29 Gene


  • Diamond-Blackfan anemia 13 (DBA13) [MIM:615909]: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. {ECO:0000269 PubMed:24829207}. Note=The disease is caused by mutations affecting the gene represented in this entry.

(1) University of Copenhagen DISEASES for RPS29 Gene

genes like me logo Genes that share disorders with RPS29: view

No data available for OMIM , Novoseek inferred disease relationships , Genatlas and External Links for RPS29 Gene

Publications for RPS29 Gene

  1. The S29 ribosomal protein increases tumor suppressor activity of K rev-1 gene on v-K ras-transformed NIH3T3 cells. (PMID: 8781548) Kondoh N. … Oikawa T. (Biochim. Biophys. Acta 1996) 2 3 4 23
  2. Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs. (PMID: 7772601) Frigerio J.-M. … Iovanna J.L. (Biochim. Biophys. Acta 1995) 2 3 4
  3. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PMID: 8706699) Vladimirov S.N. … Otto A. (Eur. J. Biochem. 1996) 3 4
  4. Regulation of the quiescence-induced genes: quiescin Q6, decorin, and ribosomal protein S29. (PMID: 10708601) Coppock D.L. … Cina-Poppe D.A. (Biochem. Biophys. Res. Commun. 2000) 3 23
  5. A map of 75 human ribosomal protein genes. (PMID: 9582194) Kenmochi N. … Page D.C. (Genome Res. 1998) 3 4

Products for RPS29 Gene

Sources for RPS29 Gene

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