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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPS27 Gene

protein-coding   GIFtS: 58
GCID: GC01P153963

Ribosomal Protein S27

(Previous name: ribosomal protein S27 (metallopanstimulin 1))
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ribosomal Protein S271 2     MPS-12 3
MPS12 3 5     Ribosomal Protein S27 (Metallopanstimulin 1)1
Metallopanstimulin 11 2     40S Ribosomal Protein S272
Metallopan-Stimulin 12 3     S272

External Ids:    HGNC: 104161   Entrez Gene: 62322   Ensembl: ENSG000001779547   OMIM: 6037025   UniProtKB: P426773   

Export aliases for RPS27 gene to outside databases

Previous GC identifers: GC01P151780 GC01P149694 GC01P150738 GC01P151181 GC01P151182 GC01P150777 GC01P152229 GC01P125325


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RPS27 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family
of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has
been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it
has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near
ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is
typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed
through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPS27 Gene: 
RPS27 (ribosomal protein S27) is a protein-coding gene. Diseases associated with RPS27 include papilloma, and gastric cancer, and among its related super-pathways are Eukaryotic Translation Initiation and Mitotic Anaphase. GO annotations related to this gene include structural constituent of ribosome and DNA binding. An important paralog of this gene is RPS27L.

Gene Wiki entry for RPS27 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPS27 gene promoter:
         AP-2gamma   C/EBPalpha   PPAR-gamma1   POU2F1   POU2F1a   AP-2beta   ZIC2/Zic2   PPAR-gamma2   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS27 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPS27

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS27


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21

RPS27 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS27 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P153963:  view genomic region     (about GC identifiers)

Start:
153,963,235 bp from pter      End:
153,964,631 bp from pter
Size:
1,397 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RS27_HUMAN, P42677 (See protein sequence)
Recommended Name: 40S ribosomal protein S27  
Size: 84 amino acids; 9461 Da
Cofactor: Binds 1 zinc ion per subunit (Potential)
Caution: Was originally (PubMed:8407955) thought to be a protein that could have played a role as a potentially
important mediator of cellular proliferative responses to various growth factors and other environmental signals.
Capable of specific binding to a cAMP response element in DNA
1 PDB 3D structure from and Proteopedia for RPS27:
3J3A (3D)    
Secondary accessions: Q5T4L6

Explore the universe of human proteins at neXtProt for RPS27: NX_P42677

Explore proteomics data for RPS27 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P42677

  • RPS27 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RPS27 Protein Expression
    REFSEQ proteins: NP_001021.1  
    ENSEMBL proteins: 
     ENSP00000357555   ENSP00000376341  
    Reactome Protein details: P42677
    Human Recombinant Protein Products for RPS27: 
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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA8407955
    GO:0005829cytosol TAS--
    GO:0005840ribosome NAS8908372
    GO:0022627cytosolic small ribosomal subunit IDA15883184

    RPS27 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RPS: S ribosomal proteins

    3 InterPro protein domains:
     IPR000592 Ribosomal_S27e
     IPR011332 Ribosomal_zn-bd_dom
     IPR023407 Ribosomal_S27e_Zn-bd_dom

    Graphical View of Domain Structure for InterPro Entry P42677

    ProtoNet protein and cluster: P42677

    1 Blocks protein domain: IPB000592 Ribosomal protein S27E

    UniProtKB/Swiss-Prot: RS27_HUMAN, P42677
    Similarity: Belongs to the ribosomal protein S27e family


    RPS27 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for RPS27:
    60S ribosomal protein S27

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding NAS8908372
    GO:0003735structural constituent of ribosome IEA--
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding NAS8407955
    GO:0046872metal ion binding ----
         
    RPS27 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for RPS27:
     Nuclear pre-40S maturation def  Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RPS27 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RPS27 About   (see all 9)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Viral mRNA Translation
    Influenza Life Cycle0.95
    3' -UTR-mediated translational regulation0.93
    Influenza Infection0.95
    L13a-mediated translational silencing of Ceruloplasmin expression0.93
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Formation of a pool of free 40S subunits0.90
    Eukaryotic Translation Termination0.94
    Nonsense-Mediated Decay0.84
    2M Phase
    Mitotic Anaphase0.94
    M Phase0.88
    Separation of Sister Chromatids0.94
    Mitotic M-M/G1 phases0.88
    Mitotic Metaphase and Anaphase0.94
    3Translation initiation complex formation
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.95
    Formation of the ternary complex, and subsequently, the 43S complex0.87
    Ribosomal scanning and start codon recognition0.95
    Translation initiation complex formation0.87
    4Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion0.93
    Mitotic Prometaphase0.93
    5Metabolism of mRNA
    Metabolism of mRNA0.92
    Metabolism of RNA0.92

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS27
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS27
        Cytoplasmic Ribosomal Proteins

    5/36        Reactome Pathways for RPS27 (see all 36)
        Mitotic Prometaphase
    Formation of a pool of free 40S subunits
    Influenza Life Cycle
    Mitotic Metaphase and Anaphase
    Viral mRNA Translation


    1         Kegg Pathway  (Kegg details for RPS27):
        Ribosome


    RPS27 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RPS27

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/148 Interacting proteins for RPS27 (P426771, 2, 3 ENSP000003575554) via UniProtKB, MINT, STRING, and/or I2D (see all 148)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MARSP561922, 3, ENSP000002620274MINT-8269340 I2D: score=2 STRING: ENSP00000262027
    RTN4Q9NQC32, 3, ENSP000003378384MINT-8269373 I2D: score=2 STRING: ENSP00000337838
    MDM2Q009871, 3, ENSP000004172814EBI-356336,EBI-389668 I2D: score=1 STRING: ENSP00000417281
    C2orf44Q9H6R72, 3MINT-8269307 I2D: score=2 
    HMP19Q9Y3282, 3MINT-8269329 I2D: score=2 
    About this table

    Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0000278mitotic cell cycle TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--

    RPS27 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RPS27 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPS27 (RS27)

    1 HMDB Compound for RPS27    About this table
    CompoundSynonyms CAS #PubMed Ids
    Cyclic AMPCyclic AMP (see all 19)60-92-4--

    1 Novoseek inferred chemical compound relationship for RPS27 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zinc 55.8 12 9404850 (1), 10556717 (1), 9179190 (1), 9216656 (1) (see all 10)

    Search CenterWatch for drugs/clinical trials and news about RPS27 / RS27

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPS27 gene: 
    NM_001030.4  

    Unigene Clusters for RPS27:

    Ribosomal protein S27
    Hs.546291  [show with all ESTs], Hs.654475  [show with all ESTs]
    Unigene Representative Sequences: BQ278503, CD556147
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368567(uc001fdv.3) ENST00000392558 ENST00000493224 ENST00000477151

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    Additional mRNA sequence: 

    AK312070.1 BC002658.2 L19739.1 

    24/104 DOTS entries (see all 104):

    DT.121136986  DT.40227959  DT.95143195  DT.100739076  DT.97849623  DT.95115492  DT.100739067  DT.100739063 
    DT.101955243  DT.102843142  DT.100739085  DT.120925364  DT.100739080  DT.92007476  DT.91649976  DT.120925355 
    DT.85101639  DT.121136915  DT.121353864  DT.121403566  DT.121353935  DT.121353870  DT.91741299  DT.100739062 

    24/1610 AceView cDNA sequences (see all 1610):

    AI707591 AA857413 AJ572025 AW089382 AA423843 T50144 BM772889 BM761763 
    AA670078 CB112554 AA302544 BC002658 AA156051 AA316014 AA357642 BM832849 
    F28017 AA541659 AA679211 AA687626 AA295965 CB152484 AA365937 U57847 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPS27 expression in normal human tissues (normalized intensities)      RPS27 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACAAACGGT
    RPS27 Expression
    About this image


    RPS27 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Bone (Muscoskeletal System)
             BONE MARROW   
     
     Blood (Muscoskeletal System)
             BONE MARROW   
     
     Brain (Nervous System)
             Adult Dopaminergic Neurons Ventral Tegmental Area
     
     Thymus (Hematopoietic System)

     -- (Endocrine System)
             pituitary   

    See RPS27 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPS27

    SOURCE GeneReport for Unigene clusters: Hs.546291 Hs.654475

    UniProtKB/Swiss-Prot: RS27_HUMAN, P42677
    Tissue specificity: Expressed in a wide variety of actively proliferating cells and tumor tissues

        SABiosciences Custom PCR Arrays for RPS27
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS27

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS27 gene from 9/26 species (see all 26)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rps271 , 5 ribosomal protein S271, 5 96.43(n)1
    100(a)1
      3 (39.21 cM)5
    572941  NM_027015.41  NP_081291.11 
     902127255 
    lizard
    (Anolis carolinensis)
    Reptilia RPS276
    40S ribosomal protein S27
    100(a)
    1 ↔ 1
    GL343805.1(101551-103790)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC053815.12   -- 83.39(n)    BC053815.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC059595.12   -- 81.54(n)   393738  BC059595.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG104233
    RpS271
    structural constituent of ribosome3
    Ribosomal protein S271
    85(a)3
    73.98(n)1
    85.37(a)1
      96C83
    430391  NM_143102.21  NP_651359.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rps-271 Protein RPS-27 68.27(n)
    79.52(a)
      178538  NM_070733.4  NP_503134.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPS27B1 Rps27bp 62.6(n)
    71.95(a)
      856415   NP_011885.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G479301 40S ribosomal protein S27-3 71.86(n)
    81.82(a)
      834844  NM_124167.3  NP_199604.1 
    rice
    (Oryza sativa)
    Liliopsida CA755866.12   -- 76.22(n)    CA755866.1 


    ENSEMBL Gene Tree for RPS27 (if available)
    TreeFam Gene Tree for RPS27 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPS27 gene
    RPS27L2  
    2 SIMAP similar genes for RPS27 using alignment to 2 protein entries:     RS27_HUMAN (see all proteins):
    RPS27L    LOC392748

    RPS27 for paralogs           About GeneDecksing


    5/14 Pseudogenes.org Pseudogenes for RPS27 (see all 14)
    PGOHUM00000238887 PGOHUM00000242928 PGOHUM00000239423 PGOHUM00000239492 PGOHUM00000246677


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/97 SNPs in RPS27 are shown (see all 97)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1399199471,2
    --153961388(+) CAACCG/TTTGTT 1 -- us2k10--------
    rs125635391,2
    C,F,H--153961784(+) gcagcG/Agcgcg 1 -- us2k11Minor allele frequency- A:0.50NA 4
    rs1842140931,2
    --153961955(+) CTCCTA/GACCTC 1 -- us2k10--------
    rs1891363831,2
    --153962200(+) CCCGTC/TTCTAC 1 -- us2k10--------
    rs125637721,2
    H--153962225(+) tagccA/Gggcat 1 -- us2k10--------
    rs125649211,2
    H--153962229(+) cgggcA/Gtggtg 1 -- us2k10--------
    rs1458903161,2
    --153962299(+) GGAGGC/TGGAGG 1 -- us2k10--------
    rs1484004771,2
    --153962327(+) GGCGCC/TATCAC 1 -- us2k10--------
    rs1439939031,2
    --153962372(+) TAAAAA/TAAAAA 1 -- us2k10--------
    rs1464398891,2
    --153962468(+) CTATTC/TAATCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RPS27 (153963235 - 153964631 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RPS27: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RPS27
    DNA2.0 Custom Variant and Variant Library Synthesis for RPS27

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603702    OMIM disorders: --

    9 diseases for RPS27:    About MalaCards
    papilloma    gastric cancer    periodontitis    influenza
    melanoma    squamous cell carcinoma    prostatitis    hepatitis
    breast cancer


    RPS27 for disorders           About GeneDecksing

    7 Novoseek inferred disease relationships for RPS27 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hnscc 58.6 9 15598348 (3), 14732777 (2), 19642098 (2)
    tumors 19.9 14 19642098 (3), 9404850 (1), 9179190 (1), 9216656 (1) (see all 9)
    carcinoma squamous cell 17.8 3 19642098 (2), 15598348 (1)
    cancer 17.2 13 19642098 (2), 12175529 (2), 16299651 (2), 10556717 (1) (see all 8)
    melanoma 17.2 7 9404850 (3), 18071315 (3), 8407955 (1)
    gastric cancer 14.4 19 16914586 (7), 16299651 (4)
    carcinoma 0 1 8407955 (1)


    Export disorders for RPS27 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPS27 gene, integrated from 9 sources (see all 74):
    (articles sorted by number of sources associating them with RPS27)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure. (PubMed id 8407955)1, 2, 3, 9 Fernandez-Pol J.A.... Hamilton P.D. (1993)
    2. Primary structures and sequence analysis of human ribosomal proteins L39 and S27. (PubMed id 8908372)1, 2, 3, 9 Tsui S.K.W.... Lee C.Y. (1996)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (2002)
    6. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2 Kenmochi N.... Page D.C. (1998)
    7. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (1996)
    8. In vitro and in vivo evidence of metallopanstimulin-1 in gastric cancer progression and tumorigenicity. (PubMed id 16914586)1, 9 Wang Y.W....Zhu Z.G. (2006)
    9. Extraribosomal function of metallopanstimulin-1: redu cing paxillin in head and neck squamous cell carcinoma and inhibiting tumor gro wth. (PubMed id 19642098)1, 9 Dai Y....Stack B.C. (2010)
    10. Metallopanstimulin gene product produced in a baculovirus expression system is a nuclear phosphoprotein that binds to DNA. (PubMed id 7986747)1, 9 Fernandez-Pol J.A....Hamilton P.D. (1994)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6232 HGNC: 10416 AceView: RPS27 Ensembl:ENSG00000177954 euGenes: HUgn6232
    ECgene: RPS27 Kegg: 6232 H-InvDB: RPS27

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPS27 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RPS27 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPS27 gene:
    Search GeneIP for patents involving RPS27

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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