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RPS26 Gene

protein-coding   GIFtS: 64
GCID: GC12P056438

Ribosomal Protein S26

  See RPS26-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein S261 2
40S Ribosomal Protein S261 2
DBA102 5
S262

External Ids:    HGNC: 104141   Entrez Gene: 62312   Ensembl: ENSG000001977287   OMIM: 6037015   UniProtKB: P628543   

Export aliases for RPS26 gene to outside databases

Previous GC identifers: GC13M099552 GC12P056999 GC12P056152 GC12P054721 GC12P054722 GC07P121716


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPS26 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S26E family
of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there
are multiple processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPS26 Gene:
RPS26 (ribosomal protein S26) is a protein-coding gene. Diseases associated with RPS26 include diamond-blackfan anemia 10, and rps26-related diamond-blackfan anemia. GO annotations related to this gene include structural constituent of ribosome and mRNA binding.

Gene Wiki entry for RPS26 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPS26 gene promoter:
         GATA-3   MAZR   FOXD1   STAT5A   Nkx2-5   AP-2gamma   AP-2beta   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS26 promoter sequence
   Search Chromatin IP Primers for RPS26

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPS26


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13   Ensembl cytogenetic band:  12q13.2   HGNC cytogenetic band: 12q13

RPS26 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS26 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P056438:  view genomic region     (about GC identifiers)

Start:
56,435,637 bp from pter      End:
56,438,116 bp from pter
Size:
2,480 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RS26_HUMAN, P62854 (See protein sequence)
Recommended Name: 40S ribosomal protein S26  
Size: 115 amino acids; 13015 Da
1 PDB 3D structure from and Proteopedia for RPS26:
3J3A (3D)    
Secondary accessions: P02383 P70394 Q06722 Q3MHD8 Q6IRY4

Explore the universe of human proteins at neXtProt for RPS26: NX_P62854

Explore proteomics data for RPS26 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys66
  • Modification sites at PhosphoSitePlus

  • See RPS26 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001020.2  
    ENSEMBL proteins: 
     ENSP00000348849   ENSP00000450339  
    Reactome Protein details: P62854

    RPS26 Human Recombinant Protein Products:

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    antibodies-online antibodies for RPS26 (12 products) 

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    antibodies-online kits for RPS26 (23 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPS: S ribosomal proteins

    1 InterPro protein domain:
     IPR000892 Ribosomal_S26e

    Graphical View of Domain Structure for InterPro Entry P62854

    ProtoNet protein and cluster: P62854

    UniProtKB/Swiss-Prot: RS26_HUMAN, P62854
    Similarity: Belongs to the ribosomal protein S26e family


    Find genes that share domains with RPS26           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPS26:
    40S ribosomal protein S26,12kDa

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003729mRNA binding IDA15716004
    GO:0003735structural constituent of ribosome IEA--
    GO:0005515protein binding IPI16189514
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with RPS26           About GenesLikeMe


    Phenotypes:
         9 GenomeRNAi human phenotypes for RPS26:
     Cytoplasmic 40S maturation def  Decreased Hepatitis C virus re  Decreased homologous recombina  Decreased viability of wild-ty 
     Increased S DNA content  Increased gamma-H2AX phosphory  Increased number of mitotic ce  Nucleolar pre-40S maturation d 
     S arrest 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RPS26

    miRNA
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    miRTarBase miRNAs that target RPS26:
    hsa-mir-196a-3p (MIRT038666), hsa-mir-26a-5p (MIRT050095), hsa-mir-139-5p (MIRT047775), hsa-mir-99a-5p (MIRT048619), hsa-mir-186-5p (MIRT045055)

    Block miRNA regulation of human, mouse, rat RPS26 using miScript Target Protectors
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    Predesigned siRNA for gene silencing in human, mouse, rat RPS26

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS26


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----

    Find genes that share ontologies with RPS26           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPS26 About   (see all 6)  
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
    Translation initiation complex formation0.91
    Ribosomal scanning and start codon recognition0.91
    Formation of the ternary complex, and subsequently, the 43S complex0.91
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.90
    4Gene Expression
    Gene Expression0.40
    5Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30


    Find genes that share SuperPaths with RPS26           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS26
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS26
        Cytoplasmic Ribosomal Proteins


    Selected Reactome Pathways for RPS26 (see all 12)
        Peptide chain elongation
    Formation of the ternary complex, and subsequently, the 43S complex
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit


    1 Kegg Pathway  (Kegg details for RPS26):
        Ribosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPS26
    Interactions:

        Search GeneGlobe Interaction Network for RPS26

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPS26 (P628541, 2, 3 ENSP000003488494) via UniProtKB, MINT, STRING, and/or I2D (see all 343)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL26P612542, 3, ENSP000002938424MINT-6542674 MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=2 STRING: ENSP00000293842
    RPL13AP404292, 3MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=1 
    RPS16P622492, 3, ENSP000002514534MINT-6542674 MINT-8044024 I2D: score=1 STRING: ENSP00000251453
    RPS12P253982, 3, ENSP000002300504MINT-8044024 I2D: score=1 STRING: ENSP00000230050
    DDX18Q9NVP12, 3MINT-6488791 I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    Find genes that share ontologies with RPS26           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPS26 (RS26)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RPS26 gene: 
    NM_001029.3  

    Unigene Clusters for RPS26:

    Ribosomal protein S26
    Hs.447562  [show with all ESTs], Hs.567235  [show with all ESTs]
    Unigene Representative Sequences: HY000542, BG254525
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000356464(uc001sjf.3) ENST00000552361 ENST00000548590
    miRNA
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    Primer
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    OriGene qPCR primer pairs and template standards for RPS26
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    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat RPS26
      QuantiTect SYBR Green Assays in human, mouse, rat RPS26
      Search QuantiFast Probe-based Assays in human, mouse, rat RPS26

    Additional mRNA sequence: 

    BC002604.1 BC013215.2 BC015832.1 X77770.1 

    Selected DOTS entries (see all 34):

    DT.100045806  DT.100693259  DT.87017935  DT.100845352  DT.99954821  DT.95367132  DT.100845353  DT.120895400 
    DT.100845351  DT.97862472  DT.100045813  DT.121257901  DT.100845348  DT.121147978  DT.121308519  DT.91742026 
    DT.100845356  DT.101986392  DT.120895608  DT.121147930  DT.121416498  DT.100845354  DT.120804222  DT.120895286 

    Selected AceView cDNA sequences (see all 86):

    CA413381 BU623060 CR611958 BQ773828 AA360942 BP354227 BU839421 BU508554 
    BG110689 BM507057 BG777482 BU954276 BV174302 BM826435 BX370921 AA346106 
    BU928418 BM553510 BE612409 BU930916 BU935543 BU602548 AA778380 T95159 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPS26 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAGGAGCTG
    RPS26 Expression
    About this image

    RPS26 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPS26 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.447562 Hs.567235
        Custom PCR Arrays for RPS26
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS26

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS26 gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rps261 , 5 ribosomal protein S261, 5 86.09(n)1
    100(a)1
      10 (77.11 cM)5
    273701  NM_013765.21  NP_038793.21 
     1286245305 
    chicken
    (Gallus gallus)
    Aves RPS261 ribosomal protein S26 82.32(n)
    98.26(a)
      100857770  XM_003643542.1  XP_003643590.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPS266
    ribosomal protein S26
    98(a)
    1 ↔ 1
    GL343198.1(3574028-3575446)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.83812 Xenopus laevis transcribed sequence with strong similarity to protein spP02383 (H.sapiens) RS26_HUMAN 40S ribosomal protein S26 less 79.17(n)    CB984062.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC059532.12   -- 81.01(n)   393715  BC059532.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpS261 , 3 protein biosynthesis structural
    constituent of ribosome less3
    Ribosomal protein S261
    83(a)3
    71.67(n)1
    86(a)1
      36E23
    350981  NM_001273608.11  NP_001260537.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rps-261 rps-26 66.67(n)
    79.21(a)
      173342  NM_061170.5  NP_493571.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPS26A(YGL189C)4
    RPS26B1
    Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Bp and has similarity to rat S26 ribosomal protein less4
    RPS26B1
    63.7(n)1
    72.28(a)1
      7(148588-148229)4
    8568681  NP_011057.11  8526864 
     NP_011326.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G405101 AT2G40510 62.71(n)
    70.3(a)
      818646  NM_129613.4  NP_181583.1 
    rice
    (Oryza sativa)
    Liliopsida CA753743.12   -- 72.88(n)    CA753743.1 


    ENSEMBL Gene Tree for RPS26 (if available)
    TreeFam Gene Tree for RPS26 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPS26 gene
    1 SIMAP similar gene for RPS26 using alignment to 2 protein entries:     RS26_HUMAN (see all proteins):
    RPS26P11

    Find genes that share paralogs with RPS26           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for RPS26 (see all 41)
    PGOHUM00000238525 PGOHUM00000238643 PGOHUM00000238846 PGOHUM00000238874 PGOHUM00000242514


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPS26 (see all 150)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0635814
    Diamond-Blackfan anemia 10 (DBA10)4--see VAR_0635812 M T mis40--------
    VAR_0635804
    Diamond-Blackfan anemia 10 (DBA10)4--see VAR_0635802 D N mis40--------
    rs1439512671,2
    C,Fpathogenic156269844(+) CCAAGA/G/TTGGTG 3 M V L mis11NS 146
    rs1450382951,2
    --56267779(+) TACTCA/GGGAGG 1 -- us2k10--------
    rs1835627631,2
    --56267979(+) AACCAC/TGATGG 1 -- us2k10--------
    rs788654651,2
    C,F--56268040(+) TAAATG/AAACAA 1 -- us2k11Minor allele frequency- A:0.08NA 120
    rs714593341,2
    C,F--56268104(+) CCTAGT/CGTCTT 1 -- us2k16Minor allele frequency- C:0.06NA CSA WA NS 354
    rs1870805231,2
    --56268122(+) GGAGAC/TAACTG 1 -- us2k10--------
    rs798395811,2
    C,F--56268157(+) CCTGCC/GAGGCT 1 -- us2k12Minor allele frequency- G:0.12WA 120
    rs594050801,2
    C,F--56268254(+) CACTGC/AAACTT 1 -- us2k11Minor allele frequency- A:0.50WA 2

    HapMap Linkage Disequilibrium report for RPS26 (56435637 - 56438116 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for RPS26:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv832427CNV Loss17160897
    nsv832424CNV Loss17160897

    Human Gene Mutation Database (HGMD): RPS26
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPS26
    DNA2.0 Custom Variant and Variant Library Synthesis for RPS26

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603701   
    OMIM disorders: 613309  
    UniProtKB/Swiss-Prot: RS26_HUMAN, P62854
  • Diamond-Blackfan anemia 10 (DBA10) [MIM:613309]: A form of Diamond-Blackfan anemia, a congenital
    non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is
    characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy.
    30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most
    frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Note=The
    disease is caused by mutations affecting the gene represented in this entry

  • 5 diseases for RPS26:    
    About MalaCards
    diamond-blackfan anemia 10    rps26-related diamond-blackfan anemia    diamond-blackfan anemia    klippel-feil syndrome
    diamond-blackfan anemia 1

    2 diseases from the University of Copenhagen DISEASES database for RPS26:
    Aplastic anemia     Klippel-Feil syndrome

    Find genes that share disorders with RPS26           About GenesLikeMe

    Genetic Association Database (GAD): RPS26

    Export disorders for RPS26 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPS26 gene, integrated from 10 sources (see all 60):
    (articles sorted by number of sources associating them with RPS26)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation, structural analysis and mapping of the functional gene of human ribosomal protein S26. (PubMed id 9602156)1, 2, 9 Filipenko M.L....Amaldi F. (Gene 1998)
    2. Cloning cDNA of human S26 ribosomal protein and determination of its primary structure. (PubMed id 7945460)1, 2, 9 Filipenko M.L....Mertvetsov N.P. (Bioorg. Khim. 1994)
    3. [Mapping of the genes for ribosomal proteins S26, L19, and L32 on human chromosomes]. (PubMed id 8670309)1, 3, 9 Filipenko M.L....Mertvetsov N.P. (Bioorg. Khim. 1995)
    4. Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia. (PubMed id 20116044)1, 2 Doherty L.... Gazda H.T. (Am. J. Hum. Genet. 2010)
    5. Genome-wide association analysis identifies three psoriasis susceptibility loci. (PubMed id 20953189)1, 4 Stuart P.E....Elder J.T. (Nat. Genet. 2010)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 3 Kenmochi N.... Page D.C. (Genome Res. 1998)
    8. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (Eur. J. Biochem. 1996)
    9. S26 ribosomal protein RNA: an invariant control for gene regulation experiments in eucaryotic cells and tissues. (PubMed id 8464749)1, 2 Vincent S.... Fort P. (Nucleic Acids Res. 1993)
    10. Human ribosomal protein S26 suppresses the splicing of its pre-mRNA. (PubMed id 15716004)1, 9 Ivanov A.V....Karpova G.G. (Biochim. Biophys. Acta 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6231 HGNC: 10414 AceView: RPS26 Ensembl:ENSG00000197728 euGenes: HUgn6231
    ECgene: RPS26 Kegg: 6231 H-InvDB: RPS26

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RPS26 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for RPS26 gene:
    Search GeneIP for patents involving RPS26

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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