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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPS25 Gene

protein-coding   GIFtS: 54
GCID: GC11M118886

ribosomal protein S25
 Explore 5 diseases affiliated with
RPS25 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RPS25    

Aliases
for RPS25 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Ribosomal Protein S251 2
S251 2
40S Ribosomal Protein S252

External Ids:    HGNC: 104131   Entrez Gene: 62302   Ensembl: ENSG000001181817   OMIM: 1804655   UniProtKB: P628513   

Export aliases for RPS25 gene to outside databases

Previous GC identifers: GC11M134077 GC11M120398 GC11M118917 GC11M118424 GC11M118391 GC11M114826


Summaries
for RPS25 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RPS25:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene
encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S25E family of
ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are
multiple processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

Gene Wiki entry for RPS25


Genomic Views
for RPS25 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_033899.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPS25 gene promoter:
         NF-1/L   NF-1   AML1a   Tal-1beta   HNF-4alpha1   Gfi-1   S8   Ik-2   Nkx6-1   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RPS25 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPS25

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS25


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.3   Ensembl cytogenetic band:  11q23.3   HGNC cytogenetic band: 11q23.3

RPS25 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS25 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M118886:  view genomic region     (about GC identifiers)

Start:
 118,886,422 bp from pter      End:
 118,889,401 bp from pter
Size:
 2,980 bases      Orientation:
 minus strand

Proteins
for RPS25 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RS25_HUMAN, P62851 (See protein sequence)
Recommended Name: 40S ribosomal protein S25  
Size: 125 amino acids; 13742 Da
Secondary accessions: B2R4M7 P25111

Explore the universe of human proteins at neXtProt for RPS25: NX_P62851

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P62851

    • RPS25 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001019.1  
    ENSEMBL proteins: 
     ENSP00000431634   ENSP00000436193   ENSP00000435096   ENSP00000436345  
    Reactome Protein details: P62851
    Human Recombinant Protein Products: 
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: RPS25
    OriGene Protein Over-expression Lysate: RPS25
    OriGene Custom Protein Services for RPS25 
    GenScript Custom Purified and Recombinant Proteins Services for RPS25
    Novus Biologicals RPS25 Protein
    Novus Biologicals RPS25 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RPS25

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA10050887
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome NAS8020948
    GO:0015935small ribosomal subunit IDA15883184


    RPS25 for ontologies           About GeneDecksing



    RPS25 Antibody Products: 
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    Uscn Antibodies for RPS25
    ThermoFisher Antibodies for RPS25

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    Uscn ELISAs and CLIAs for RPS25

    Protein Domains /
    Families
    for RPS25 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RPS25 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR004977 Ribosomal_S25

    Graphical View of Domain Structure for InterPro Entry P62851

    ProtoNet protein and cluster: P62851

    UniProtKB/Swiss-Prot: RS25_HUMAN, P62851
    Similarity: Belongs to the ribosomal protein S25e family


    Function
    for RPS25 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
         Genatlas biochemistry entry for RPS25:
    40S ribosomal protein S25,13kDa

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPS25
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    SwitchGear 3'UTR luciferase reporter plasmid: RPS25 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS25 (see all 7)
    OriGene shRNA RFP: RPS25
    OriGene siRNA: RPS25
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS25

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for RPS25

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPS25 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPS25
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    GenScript: all cDNA clones in your preferred vector: RPS25 (NM_001028)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPS25
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS25 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for RPS25
    Search LifeMap BioReagents cell lines for RPS25

    In Situ Assay
    Products:       
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS25

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding NAS10050887
    GO:0003735structural constituent of ribosome IEA--


    RPS25 for ontologies           About GeneDecksing


    4 GenomeRNAi human phenotypes for RPS25:
     Decreased Hepatitis C virus re  Decreased number of cells in m  Decreased viability  Synthetic lethal with Ras 


    Pathways & Interactions
    for RPS25 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    		Viral Protein Synthesis1.00
    		Cytoplasmic Ribosomal Proteins0.86
    		Viral mRNA Translation1.00
    		CFTR translational fidelity (class I mutations)0.83
    		Influenza Viral RNA Transcription and Replication1.00
    		SMG6 Cleaves mRNA with Premature Termination Codon0.80
    		Synthesis of nascent polypeptide containing signal sequence1.00
    		L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Translation initiation complex formation
    		Translation initiation complex formation1.00
    		Ribosomal scanning and start codon recognition0.96
    		Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.98
    		Formation of the ternary complex, and subsequently, the 43S complex0.87
    3Metabolism of mRNA
    		Metabolism of mRNA1.00
    		Metabolism of RNA0.92
    4Disease
    		Disease1.00
    5Generic Transcription Pathway
    		Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS25
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS25 
        Cytoplasmic Ribosomal Proteins

    5/32        Reactome Pathways for RPS25 (see all 32)
        Formation of a pool of free 40S subunits
    Synthesis of PB1-F2
    SMG6 Cleaves mRNA with Premature Termination Codon
    Influenza Life Cycle
    Viral mRNA Translation


    1         Kegg Pathway  (Kegg details for RPS25):
        Ribosome


    RPS25 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPS25

    5/608 Interacting proteins for RPS25 (P628511, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 608)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UPF2Q9HAU51, 2, 3EBI-353054,EBI-372073 MINT-7945693 I2D: score=4 
    SGSM2O431472, 3MINT-64869 I2D: score=4 
    HAP1P542572, 3MINT-63978 I2D: score=3 
    CDC5LQ994592, 3MINT-7945693 I2D: score=1 
    HNRNPKP619782, 3MINT-7945693 I2D: score=1 
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000028ribosomal small subunit assembly IEA--
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--


    RPS25 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RPS25 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPS25
    Search CenterWatch for drugs/clinical trials and news about RPS25 / RS25 

    Transcripts
    for RPS25 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RPS25 gene: 
    NM_001028.2  

    Unigene Cluster for RPS25:

    Ribosomal protein S25
    Hs.512676  [show with all ESTs]
    Unigene Representative Sequence: BE896735
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000532567 ENST00000527791 ENST00000527673(uc001pun.2) ENST00000530602
    ENST00000527853 ENST00000524864 ENST00000528547

    miRNA
    Products:             		 OriGene 3'-UTR Clone: RPS25
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPS25
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    SwitchGear 3'UTR luciferase reporter plasmid: RPS25 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS25 (see all 7)
    OriGene shRNA RFP: RPS25
    OriGene siRNA: RPS25
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS25
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPS25 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPS25
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    GenScript: all cDNA clones in your preferred vector: RPS25 (NM_001028)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPS25
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS25 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RPS25
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS25
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS25

    Additional cDNA sequence: 

    AK311883.1 BC004294.1 BC004986.1 M64716.1 

    24/70 DOTS entries (see all 70):

    DT.100856812  DT.100741008  DT.95285703  DT.100704842  DT.100773074  DT.100704826  DT.120718572  DT.120718579 
    DT.100823290  DT.95248460  DT.100037918  DT.92041427  DT.100849948  DT.120718638  DT.100704838  DT.101962932 
    DT.100823294  DT.100704829  DT.120718706  DT.100704827  DT.120718701  DT.220747  DT.120718715  DT.97818376 

    24/820 AceView cDNA sequences (see all 820):

    BE302551 BM695340 BP368245 BE047794 BU741826 BU070474 BM671259 BX352994 
    BU500632 H46084 BM711610 AA488565 AL555504 BM710095 CB243355 R71282 
    BQ007464 AA405314 BG749640 BQ447976 AA076312 BQ614145 CD672174 AA079062 

    GeneLoc Exon Structure


    Expression
    for RPS25 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPS25 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AATAGGTCCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    RPS25 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Endoderm-like cells (Generation of hepato...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RPS25 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPS25

    SOURCE GeneReport for Unigene cluster: Hs.512676
        SABiosciences Custom PCR Arrays for RPS25
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS25
    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS25

    Orthologs
    for RPS25 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS25 gene from 10/37 species (see all 37)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Rps251 , 5 ribosomal protein S251, 5 88.53(n)1
    100(a)1    		   9 (24.84 cM)5
    756171  NM_024266.31  NP_077228.11 
     444077145 
    chicken
    (Gallus gallus)    		 Aves RPS251 ribosomal protein S25 82.13(n)
    99.2(a)    		   770722  XM_001234051.2  XP_001234052.1 
    lizard
    (Anolis carolinensis)    		 Reptilia RPS256
    		 --
    		 98(a)
    		 1 ↔ 1
    		 GL344273.1(10844-12029)
    African clawed frog
    (Xenopus laevis)    		 Amphibia CD301620.12   -- 81.44(n)    CD301620.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc733912 hypothetical protein MGC73391 77.48(n)   393788  BC059695.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta RpS251 Ribosomal protein S25 66.95(n)
    70.94(a)    		   41343  NM_079591.5  NP_524315.2 
    worm
    (Caenorhabditis elegans)    		 Secernentea rps-251 Protein RPS-25 62.24(n)
    69.03(a)    		   177365  NM_068494.4  NP_500895.1 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes RPS25A1 Rps25ap 53.33(n)
    49.52(a)    		   852911   NP_011541.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT4G345551 40S ribosomal protein S25-3 56.48(n)
    60.19(a)    		   829607  NM_119621.2  NP_567968.1 
    rice
    (Oryza sativa)    		 Liliopsida Os.229782 Transcribed sequence with weak similarity to protein more 76.22(n)    CA755026.1 


    ENSEMBL Gene Tree for RPS25 (if available)
    TreeFam Gene Tree for RPS25 (if available) 

    Paralogs
    for RPS25 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPS25 gene

    RPS25 for paralogs           About GeneDecksing


    5/8 Pseudogenes.org Pseudogenes for RPS25 (see all 8)
    PGOHUM00000238523 PGOHUM00000245196 PGOHUM00000246601 PGOHUM00000239987 PGOHUM00000237631


    Genomic Variants
    for RPS25 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/160 NCBI SNPs in RPS25 are shown (see all 160)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 11 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1395022161,2
    		F--118885945(+) AGCCTG/CGACAA 2 -- ds5001 int11Minor allele frequency- C:0.03NS 128
    rs2019110901,2
    		--118885977(+) TATTCG/TTCAAT 2 -- int1 ds50010--------
    rs1391273361,2
    		--118885993(+) AAAAT-/AAAAGTT 2 -- ds5001 int10--------
    rs2010124351,2
    		--118886007(+) CCTATC/TATTGT 2 -- ds5001 int10--------
    rs2010527531,2
    		--118886226(+) TCGTGA/TTAACC 2 -- int1 ds50010--------
    rs1392037131,2
    		C,--118886358(+) AACCC-/CTACTATT 2 -- ut31 ds50010--------
    rs769046531,2
    		C,F,--118886401(+) TCTTAG/AGAAAC 2 -- ut31 ds50012Minor allele frequency- A:0.05WA NS 266
    rs1447763711,2
    		--118886485(+) AATTAA/TAAGAA 2 -- int1 ds50010--------
    rs1830370531,2
    		C,--118886580(+) CTGGAA/GCATCT 3 A V ds5001 mis10--------
    rs1498253231,2
    		C,F,--118886603(+) TTTCTG/AGTGTA 3 /T syn1 ds50013Minor allele frequency- A:0.02NS NA EU 6021

    HapMap Linkage Disequilibrium report for RPS25 (118886422 - 118889401 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RPS25: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPS25
    DNA2.0 Custom Variant and Variant Library Synthesis for RPS25

    Disorders / Diseases
    for RPS25 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RPS25 for disorders           About GeneDecksing

    OMIM gene information: 180465    OMIM disorders: --

    5 diseases for RPS25:    About MalaCards
    diamond-blackfan anemia    pandas    anemia    malaria
    alcoholism

    1 disease from the University of Copenhagen DISEASES database for RPS25:
    Diamond-Blackfan anemia

    Export disorders for RPS25 gene to outside databases

    Publications
    for RPS25 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPS25 gene, integrated from 9 sources (see all 49):
    (articles sorted by number of sources associating them with RPS25)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and sequencing a cDNA encoding human ribosomal protein S25. (PubMed id 1748303)1, 2, 3, 9 Li M.... Center M.S. (1991)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (2002)
    4. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (1996)
    5. Nuclear and nucleolar targeting of human ribosomal protein S25: common features shared with HIV-1 regulatory proteins. (PubMed id 10050887)1, 9 Kubota S....Pomerantz R.J. (1999)
    6. Assignment of the human ribosomal protein S25 gene (RPS25) to chromosome 11q23.3 by sequence analysis of the marker D11S456. (PubMed id 8020948)1, 9 Imai T....Miwa T. (1994)
    7. Regulation of ribosomal protein S25 in HL60 cells isolated for resistance to adriamycin. (PubMed id 1544436)1, 9 Li M. and Center M.S. (1992)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
    10. A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)

    External Searches for RPS25 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing RPS25 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6230 HGNC: 10413 AceView: RPS25.1 Ensembl:ENSG00000118181 euGenes: HUgn6230
    ECgene: RPS25 Kegg: 6230 H-InvDB: RPS25

    Other Databases showing RPS25 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RPS25 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPS25 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for RPS25 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RPS25 gene:
    Search GeneIP for patents involving RPS25

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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