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RPS23 Gene

protein-coding   GIFtS: 60
GCID: GC05M081569

Ribosomal Protein S23

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein S231 2
40S Ribosomal Protein S232
S232
Homolog Of Yeast Ribosomal Protein S282

External Ids:    HGNC: 104101   Entrez Gene: 62282   Ensembl: ENSG000001864687   OMIM: 6036835   UniProtKB: P622663   

Export aliases for RPS23 gene to outside databases

Previous GC identifers: GC05M080389 GC05M081796 GC05M081608 GC05M081655 GC05M081607 GC05M076778


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPS23 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12P family
of ribosomal proteins. It is located in the cytoplasm. The protein shares significant amino acid similarity with
S. cerevisiae ribosomal protein S28. As is typical for genes encoding ribosomal proteins, there are multiple
processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPS23 Gene:
RPS23 (ribosomal protein S23) is a protein-coding gene. Diseases associated with RPS23 include pasteurellosis, and cancer progression/metastasis. GO annotations related to this gene include structural constituent of ribosome.

Gene Wiki entry for RPS23 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000005.10  NC_018916.2  NT_034772.7  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPS23 gene promoter:
         Elk-1   Nkx2-2   SREBP-1c   Olf-1   SREBP-1b   MEF-2A   SREBP-1a   FOXO1a   aMEF-2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS23 promoter sequence
   Search Chromatin IP Primers for RPS23

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPS23


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q14.2   Ensembl cytogenetic band:  5q14.2   HGNC cytogenetic band: 5q14.2

RPS23 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS23 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M081569:  view genomic region     (about GC identifiers)

Start:
81,569,139 bp from pter      End:
81,574,396 bp from pter
Size:
5,258 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RS23_HUMAN, P62266 (See protein sequence)
Recommended Name: 40S ribosomal protein S23  
Size: 143 amino acids; 15808 Da
1 PDB 3D structure from and Proteopedia for RPS23:
3J3A (3D)    
Secondary accessions: P39028 Q6IB08

Explore the universe of human proteins at neXtProt for RPS23: NX_P62266

Explore proteomics data for RPS23 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys37, Lys48, Lys54
  • Modification sites at PhosphoSitePlus

  • See RPS23 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001016.1  
    ENSEMBL proteins: 
     ENSP00000296674   ENSP00000427043   ENSP00000425865   ENSP00000425833   ENSP00000422071  
     ENSP00000420900  
    Reactome Protein details: P62266

    RPS23 Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for RPS23


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPS: S ribosomal proteins

    3 InterPro protein domains:
     IPR006032 Ribosomal_S12/S23
     IPR012340 NA-bd_OB-fold
     IPR005680 Ribosomal_S23_euk/arc

    Graphical View of Domain Structure for InterPro Entry P62266

    ProtoNet protein and cluster: P62266

    UniProtKB/Swiss-Prot: RS23_HUMAN, P62266
    Similarity: Belongs to the ribosomal protein S12P family


    RPS23 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPS23:
    60S ribosomal protein S23

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0003735structural constituent of ribosome IEA--
    GO:0005515protein binding IPI--
    GO:0044822poly(A) RNA binding IDA--
         
    RPS23 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for RPS23:
     Decreased Hepatitis C virus re  Increased S DNA content  Increased gamma-H2AX phosphory  Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPS23
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    miRNA
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    miRTarBase miRNAs that target RPS23:
    hsa-mir-92a-3p (MIRT049724), hsa-mir-484 (MIRT042095), hsa-mir-33a-5p (MIRT049851), hsa-mir-1274a (MIRT035842), hsa-mir-1915-5p (MIRT035773)

    Block miRNA regulation of human, mouse, rat RPS23 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate RPS23:
    hsa-miR-556-3p hsa-miR-3647-3p hsa-miR-4282
    SwitchGear 3'UTR luciferase reporter plasmidRPS23 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RPS23
    Predesigned siRNA for gene silencing in human, mouse, rat RPS23

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS23

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS23


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    mitochondrion2
    nucleus1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome NAS8415000

    RPS23 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPS23 About   (see all 6)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
    Translation initiation complex formation0.91
    Ribosomal scanning and start codon recognition0.91
    Formation of the ternary complex, and subsequently, the 43S complex0.91
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.90
    4Gene Expression
    Gene Expression0.40
    5Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS23
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS23
        Cytoplasmic Ribosomal Proteins

    Selected Reactome Pathways for RPS23 (see all 12)
        Peptide chain elongation
    Formation of the ternary complex, and subsequently, the 43S complex
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit


    1 Kegg Pathway  (Kegg details for RPS23):
        Ribosome


    RPS23 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPS23
    Interactions:

        Search GeneGlobe Interaction Network for RPS23

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPS23 (P622661, 2, 3 ENSP000002966744) via UniProtKB, MINT, STRING, and/or I2D (see all 450)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPS2P158802, 3, ENSP000003418854MINT-6542674 MINT-6488590 I2D: score=3 STRING: ENSP00000341885
    RPS3P233962, 3, ENSP000002785724MINT-6542674 MINT-6488590 I2D: score=3 STRING: ENSP00000278572
    RPS6P627532, 3, ENSP000003697574MINT-6542674 MINT-6488590 I2D: score=2 STRING: ENSP00000369757
    RPL35P427662, 3, ENSP000002594694MINT-6488590 I2D: score=5 STRING: ENSP00000259469
    RPL26P612542, 3MINT-6542674 MINT-6488590 I2D: score=4 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPS23 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPS23 (RS23)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RPS23 gene: 
    NM_001025.4  

    Unigene Cluster for RPS23:

    Ribosomal protein S23
    Hs.527193  [show with all ESTs]
    Unigene Representative Sequence: AK125939
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296674(uc003khu.3) ENST00000510210 ENST00000512493 ENST00000510019
    ENST00000507980 ENST00000504293 ENST00000503605 ENST00000511844
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    Block miRNA regulation of human, mouse, rat RPS23 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate RPS23:
    hsa-miR-556-3p hsa-miR-3647-3p hsa-miR-4282
    SwitchGear 3'UTR luciferase reporter plasmidRPS23 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: RPS23 (NM_001025)
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      QuantiTect SYBR Green Assays in human, mouse, rat RPS23
      QuantiFast Probe-based Assays in human, mouse, rat RPS23

    Additional mRNA sequence: 

    AK092335.1 AK125939.1 AK291132.1 AK311772.1 BC046998.1 BC070221.1 BX647563.1 CR456996.1 
    D14530.1 M32219.1 

    Selected DOTS entries (see all 50):

    DT.91866256  DT.100706557  DT.100706570  DT.100706573  DT.100869920  DT.95280798  DT.100706560  DT.95109956 
    DT.100706558  DT.100868645  DT.100801358  DT.95280794  DT.100861683  DT.450305  DT.120863112  DT.100059971 
    DT.75147562  DT.120863261  DT.101955245  DT.120863207  DT.120863352  DT.86997486  DT.97759859  DT.100706559 

    Selected AceView cDNA sequences (see all 1379):

    BG109842 AA363500 BQ061674 BF055148 AW327840 AI189988 CB117391 CB139054 
    CB108234 BM711226 BM874099 CB137260 AA307553 CB111614 CB126119 CB130779 
    BQ214950 CD676540 AW043594 BG875793 BM855895 BG577053 BM830873 BQ934490 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RPS23    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6 ^ 7
    SP1:                                            -     -     -               
    SP2:              -     -                                                   
    SP3:                                                                        
    SP4:              -     -                                                   
    SP5:                                                                        


    ECgene alternative splicing isoforms for RPS23

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPS23 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGTTGGTGA
    RPS23 Expression
    About this image

    RPS23 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPS23 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.527193
        Custom PCR Arrays for RPS23
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat RPS23
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS23

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS23 gene from Selected species (see all 30)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rps231 , 5 ribosomal protein S231, 5 89.74(n)1
    100(a)1
      13 (46.46 cM)5
    664751  NM_024175.31  NP_077137.11 
     909231225 
    chicken
    (Gallus gallus)
    Aves RPS231 ribosomal protein S23 83.92(n)
    100(a)
      427323  XM_424903.4  XP_424903.3 
    lizard
    (Anolis carolinensis)
    Reptilia RPS236
    ribosomal protein S23
    100(a)
    1 ↔ 1
    2(17979516-17986997)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.258362 Xenopus laevis transcribed sequence with strong similarity more 82.87(n)    CB591090.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rps231 ribosomal protein S23 84.15(n)
    98.6(a)
      100000341  NM_001110121.1  NP_001103591.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG84153
    RpS231
    protein biosynthesis structural
    constituent of more3
    Ribosomal protein S231
    90(a)3
    76.46(n)1
    90.91(a)1
      50E43
    365761  NM_137095.21  NP_610939.21 
    worm
    (Caenorhabditis elegans)
    Secernentea rps-231 , 3 ribosomal protein S233
    rps-231
    84(a)3
    71.79(n)1
    84.62(a)1
      IV(12390368-12391480)3
    1781881  NM_069964.51  NP_502365.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPS23A(YGR118W)4
    RPS23A1
    Ribosomal protein 28 (rp28) of the small (40S) ribosomal more4
    RPS23A1
    68.31(n)1
    78.17(a)1
      7(726974-727730)4
    8530151, 4  NP_011633.31  NP_011633.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G096801 AT3G09680 69.95(n)
    76.06(a)
      820125  NM_111802.1  NP_566351.1 
    rice
    (Oryza sativa)
    Liliopsida Os.90752 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 76.15(n)    AK102675.1 


    ENSEMBL Gene Tree for RPS23 (if available)
    TreeFam Gene Tree for RPS23 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPS23 gene

    RPS23 for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for RPS23 (see all 11)
    PGOHUM00000248985 PGOHUM00000250844 PGOHUM00000244312 PGOHUM00000244313 PGOHUM00000245616


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPS23 (see all 186)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1133916091,2
    C,F--81568850(+) CTGGAC/TTCCAA 1 -- ds50011Minor allele frequency- T:0.50NA 2
    rs1121459571,2
    C,F--81568895(+) ACTGTG/ATTAAT 1 -- ds50012Minor allele frequency- A:0.07WA 120
    rs1874584411,2
    --81568905(+) TCCTCC/TGCAGG 1 -- ds50010--------
    rs1474011261,2
    --81568906(+) CCTCCA/GCAGGG 1 -- ds50010--------
    rs731387871,2
    C,F--81568934(+) CTGGCG/AAGGCG 1 -- ds50016Minor allele frequency- A:0.32NA WA CSA NS 393
    rs716362981,2
    C,F--81568947(+) CCACCG/AGGGCA 1 -- ds50012Minor allele frequency- A:0.50NA 4
    rs1831497661,2
    --81568953(+) GGGCAA/GCTGCC 1 -- ds50010--------
    rs606015871,2
    C,F--81568966(+) CCCAGG/CAGCAC 1 -- ds50013Minor allele frequency- C:0.02WA NS 270
    rs1381304341,2
    C--81568998(+) GCTGGC/TCGGAG 1 -- ds50010--------
    rs1161511411,2
    C,F--81569000(+) TGGCCG/AGAGTC 1 -- ds50011Minor allele frequency- A:0.04WA 118

    HapMap Linkage Disequilibrium report for RPS23 (81569139 - 81574396 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RPS23:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2676657CNV Deletion23128226
    nsv830364CNV Loss17160897
    nsv520938CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPS23
    DNA2.0 Custom Variant and Variant Library Synthesis for RPS23

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603683    OMIM disorders: --

    12 diseases for RPS23:    About MalaCards
    pasteurellosis    cancer progression/metastasis    ascariasis    trichuriasis
    diamond-blackfan anemia    endometriosis    influenza    hiv-1
    colorectal cancer    prostate cancer    breast cancer    prostatitis

    1 disease from the University of Copenhagen DISEASES database for RPS23:
    Pasteurellosis

    RPS23 for disorders           About GeneDecksing


    Export disorders for RPS23 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPS23 gene, integrated from 10 sources (see all 53):
    (articles sorted by number of sources associating them with RPS23)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (Genome Res. 1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (Eur. J. Biochem. 1996)
    4. A cDNA sequence of human ribosomal protein, homologue of yeast S28. (PubMed id 8415000)1, 2 Hori N.... Matsubara K. (Nucleic Acids Res. 1993)
    5. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....YA!A+ez-MA^ M. (J. Biol. Chem. 2013)
    6. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    7. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (Biochem. J. 2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6228 HGNC: 10410 AceView: RPS23 Ensembl:ENSG00000186468 euGenes: HUgn6228
    ECgene: RPS23 Kegg: 6228 H-InvDB: RPS23

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RPS23 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPS23 gene:
    Search GeneIP for patents involving RPS23

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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