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RPS20 Gene

protein-coding   GIFtS: 61
GCID: GC08M056982

Ribosomal Protein S20

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein S201 2
40S Ribosomal Protein S202
S202

External Ids:    HGNC: 104051   Entrez Gene: 62242   Ensembl: ENSG000000089887   OMIM: 6036825   UniProtKB: P608663   

Export aliases for RPS20 gene to outside databases

Previous GC identifers: GC08M056164 GC08M056924 GC08M056704 GC08M057035 GC08M057148


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPS20 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10P family
of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the small nucleolar RNA
gene U54, which is located in its second intron. As is typical for genes encoding ribosomal proteins, there are
multiple processed pseudogenes of this gene dispersed through the genome. Two transcript variants encoding
different isoforms have been identified for this gene. (provided by RefSeq, Apr 2009)

GeneCards Summary for RPS20 Gene:
RPS20 (ribosomal protein S20) is a protein-coding gene. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for RPS20 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NC_018919.2  NT_008183.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPS20 gene promoter:
         ISGF-3   AP-1   p53   Ik-3   AP-2gamma   RORalpha2   c-Ets-1   AP-2beta   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS20 promoter sequence
   Search Chromatin IP Primers for RPS20

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPS20


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q12   Ensembl cytogenetic band:  8q12.1   HGNC cytogenetic band: 8q12.1

RPS20 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS20 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M056982:  view genomic region     (about GC identifiers)

Start:
56,979,854 bp from pter      End:
56,987,140 bp from pter
Size:
7,287 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RS20_HUMAN, P60866 (See protein sequence)
Recommended Name: 40S ribosomal protein S20  
Size: 119 amino acids; 13373 Da
Subunit: Component of the 40S small ribosomal subunit (By similarity)
1 PDB 3D structure from and Proteopedia for RPS20:
3J3A (3D)    
Secondary accessions: B2R4F4 B4DW28 P17075 Q5M8S9
Alternative splicing: 2 isoforms:  P60866-1   P60866-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RPS20: NX_P60866

Explore proteomics data for RPS20 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys4, Lys8, Lys30, Lys34, Lys67, Lys75
  • Modification sites at PhosphoSitePlus

  • See RPS20 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001014.1  NP_001139699.1  

    ENSEMBL proteins: 
     ENSP00000429374   ENSP00000009589   ENSP00000429049   ENSP00000427788   ENSP00000427860  
     ENSP00000428104   ENSP00000429333   ENSP00000428146  
    Reactome Protein details: P60866

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    Cloud-Clone Corp. Proteins for RPS20

     
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    antibodies-online proteins for RPS20 (13 products) 

     
    antibodies-online peptides for RPS20

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPS: S ribosomal proteins

    4 InterPro protein domains:
     IPR001848 Ribosomal_S10
     IPR018268 Ribosomal_S10_CS
     IPR027486 Ribosomal_S10_dom
     IPR005729 Ribosomal_S10_euk/arc

    Graphical View of Domain Structure for InterPro Entry P60866

    ProtoNet protein and cluster: P60866

    UniProtKB/Swiss-Prot: RS20_HUMAN, P60866
    Similarity: Belongs to the ribosomal protein S10P family


    Find genes that share domains with RPS20           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPS20:
    40S ribosomal protein S20

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding NAS8479924
    GO:0003735structural constituent of ribosome NAS8479924
    GO:0005515protein binding IPI18274552
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with RPS20           About GenesLikeMe


    Phenotypes:
         8 GenomeRNAi human phenotypes for RPS20:
     Cytoplasmic 40S maturation def  Decreased Hepatitis C virus re  Decreased cell number, increas  Decreased nuclei size in G2M 
     Decreased viability of wild-ty  Increased number of mitotic ce  Nucleolar pre-40S maturation d  S arrest 

         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rps20):
     integument  limbs/digits/tail  mortality/aging  pigmentation 

    Find genes that share phenotypes with RPS20           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RPS20

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    GenScript: all cDNA clones in your preferred vector (see all 2): RPS20 (NM_001023)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS20

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS20


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RS20_HUMAN, P60866: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus2
    plasma membrane2
    chloroplast1
    endoplasmic reticulum1
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0015935small ribosomal subunit ----
    GO:0022627cytosolic small ribosomal subunit IDA15883184

    Find genes that share ontologies with RPS20           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPS20 About   (see all 6)  
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
    Translation initiation complex formation0.91
    Ribosomal scanning and start codon recognition0.91
    Formation of the ternary complex, and subsequently, the 43S complex0.91
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.90
    4Gene Expression
    Gene Expression0.40
    5Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30


    Find genes that share SuperPaths with RPS20           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS20
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS20
        Cytoplasmic Ribosomal Proteins

    Selected Reactome Pathways for RPS20 (see all 12)
        Peptide chain elongation
    Formation of the ternary complex, and subsequently, the 43S complex
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit


    1 Kegg Pathway  (Kegg details for RPS20):
        Ribosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPS20
    Interactions:

        GeneGlobe Interaction Network for RPS20

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPS20 (P608661, 2, 3 ENSP000000095894) via UniProtKB, MINT, STRING, and/or I2D (see all 505)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL23P628292, 3, ENSP000003778654MINT-6542674 MINT-6489217 MINT-6489539 I2D: score=2 STRING: ENSP00000377865
    RPS3P233962, 3, ENSP000002785724MINT-6542674 MINT-6489539 I2D: score=5 STRING: ENSP00000278572
    RPS15AP622442, 3, ENSP000003186464MINT-6542674 MINT-6489539 I2D: score=4 STRING: ENSP00000318646
    RPL11P629132, 3, ENSP000003636764MINT-6542674 MINT-6489539 I2D: score=3 STRING: ENSP00000363676
    RPL12P300502, 3, ENSP000003547394MINT-6542674 MINT-6489539 I2D: score=2 STRING: ENSP00000354739
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    Find genes that share ontologies with RPS20           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPS20 (RS20)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RPS20 gene (2 alternative transcripts): 
    NM_001023.3  NM_001146227.1  

    Unigene Cluster for RPS20:

    Ribosomal protein S20
    Hs.8102  [show with all ESTs]
    Unigene Representative Sequence: BQ053882
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000519807(uc003xsm.2) ENST00000009589(uc003xsn.2) ENST00000524349
    ENST00000520490 ENST00000521262 ENST00000520627 ENST00000523936 ENST00000519606
    ENST00000521289 ENST00000518875 ENST00000519369
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat RPS20
      QuantiFast Probe-based Assays in human, mouse, rat RPS20

    Additional mRNA sequence: 

    AK130961.1 AK301342.1 AK311808.1 BC007507.2 BC087850.1 D28358.1 L06498.1 

    Selected DOTS entries (see all 95):

    DT.100741479  DT.98083175  DT.75120818  DT.100741514  DT.91867386  DT.91949530  DT.100855793  DT.91784069 
    DT.95210310  DT.91964648  DT.121470087  DT.100893924  DT.92045974  DT.100851177  DT.91784086  DT.100741495 
    DT.91801971  DT.91995465  DT.121469955  DT.99926488  DT.101956696  DT.121470098  DT.100741492  DT.121470090 

    Selected AceView cDNA sequences (see all 2784):

    BM764012 CB124733 T91540 BE789998 AA345465 AJ573743 BQ270647 BE796034 
    BG283248 BM838385 AW769403 BE267226 BF726424 AJ713734 AA188016 CB133499 
    N88661 BQ225297 CD677627 BP430826 CF127336 AI262243 BE886991 CD107176 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RPS20 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c
    SP1:                                -                       -                     
    SP2:                                -                 -     -                     
    SP3:                                                        -                     
    SP4:                                -                                             
    SP5:                                                                              


    ECgene alternative splicing isoforms for RPS20

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPS20 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTTTTAAGG
    RPS20 Expression
    About this image


    RPS20 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 24) fully expand
     
     Ovary (Reproductive System)
             Primary Oocyte Primary Follicle
     
     Thymus (Hematopoietic System)
             Double Negative 2 Thymocytes Thymus
     
     Gonad
             Primary Oocyte Primary Follicle
     
     Blood (Cardiovascular System)
             Double Negative 2 Thymocytes Thymus
     
     Brain (Nervous System)
             Cerebral Cortex
    RPS20 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPS20 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.8102
        Custom PCR Arrays for RPS20
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat RPS20
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS20

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS20 gene from Selected species (see all 28)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rps201 , 5 ribosomal protein S201, 5 89.64(n)1
    100(a)1
      4 (2.14 cM)5
    674271  NM_026147.51  NP_080423.11 
     38313345 
    chicken
    (Gallus gallus)
    Aves RPS201 ribosomal protein S20 82.63(n)
    98.32(a)
      430990  XM_428540.4  XP_428540.3 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.17872 Xenopus laevis transcribed sequence with strong similarity more 81.61(n)    CB941110.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.2802 Danio rerio cDNA clone MGC77758 IMAGE7000995, complete more 80.54(n)    BC062282.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpS201 , 3 protein biosynthesis structural
    constituent of more3
    Ribosomal protein S201
    81(a)3
    69.23(n)1
    81.2(a)1
      93A13
    424641  NM_079697.31  NP_524421.11 
    worm
    (Caenorhabditis elegans)
    Secernentea Y105E8A.163
    rps-201
    rps-201 80(a)3
    66.01(n)1
    80.2(a)1
      I(14476520-14477058)3
    1733091  NM_170948.41  NP_740944.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPS20(YHL015W)4
    RPS201
    Protein component of the small (40S) ribosomal subunit; more4
    RPS201
    64.03(n)1
    62.38(a)1
      8(75412-75777)4
    8563711, 4  NP_011848.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G623001 AT5G62300 68.21(n)
    74.07(a)
      836351  NM_125624.3  NP_201036.1 
    rice
    (Oryza sativa)
    Liliopsida AK062184.12   -- 72.65(n)    AK062184.1 


    ENSEMBL Gene Tree for RPS20 (if available)
    TreeFam Gene Tree for RPS20 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPS20 gene

    Find genes that share paralogs with RPS20           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for RPS20 (see all 37)
    PGOHUM00000242223 PGOHUM00000242376 PGOHUM00000239311 PGOHUM00000239612 PGOHUM00000239639


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPS20 (see all 195)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1875078131,2
    --56980280(+) ATGATA/GTGGTA 1 -- ds50010--------
    rs78123371,2
    C,F,H--56980480(+) aagacA/Gaaaga 1 -- ds50015Minor allele frequency- G:0.07NS EA WA 536
    rs735923391,2
    C--56980528(+) TAATGC/TTACAG 1 -- ds50011Minor allele frequency- T:0.50WA 2
    rs1383426151,2
    C--56980540(+) CTGTT-/AAGAAA 1 -- ds50010--------
    rs29760091,2
    C,F,H--56980542(-) cttttC/Ttaaca 1 -- ds500110Minor allele frequency- T:0.29NS EA WA NA CSA 428
    rs29538971,2
    C,F--56980569(+) AGATAC/TTAGAA 1 -- ds50011Minor allele frequency- T:0.19NA 120
    rs1855183771,2
    --56980665(+) ATAAAA/GCTGGT 1 -- ds50010--------
    rs1908279271,2
    --56980679(+) AGTTGA/GCAATC 1 -- ds50010--------
    rs64740411,2
    C,F,A,H--56980715(+) ccattC/Gtctct 1 -- ds50015Minor allele frequency- G:0.08NS EA WA 536
    rs1925314151,2
    --56980735(+) TGTATA/GTTTGA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for RPS20 (56979854 - 56987140 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RPS20:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv524526CNV Loss19592680
    nsv525972CNV Loss19592680
    nsv831319CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPS20
    DNA2.0 Custom Variant and Variant Library Synthesis for RPS20

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603682    OMIM disorders: --


    Find genes that share disorders with RPS20           About GenesLikeMe

    1 Novoseek inferred disease relationship for RPS20 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 1 17373842 (1)

    Genetic Association Database (GAD): RPS20
    Human Genome Epidemiology (HuGE) Navigator: RPS20 (1 document)

    Export disorders for RPS20 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPS20 gene, integrated from 10 sources (see all 75):
    (articles sorted by number of sources associating them with RPS20)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (Genome Res. 1998)
    2. Human ribosomal protein S20 cDNA sequence. (PubMed id 8479924)1, 2, 3 Chu W.... Burns D.K. (Nucleic Acids Res. 1993)
    3. The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. (PubMed id 20546612)1, 4 Zhao J....Grant S.F. (BMC Med. Genet. 2010)
    4. Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1, 4 Gudbjartsson D.F....Stefansson K. (Nat. Genet. 2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (Genome Res. 2002)
    7. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (Eur. J. Biochem. 1996)
    8. Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8. (PubMed id 16968546)1, 9 De Bortoli M....Kim J.Y. (BMC Cancer 2006)
    9. HDM2-binding partners: interaction with translation elongation factor EF1alpha. (PubMed id 17373842)1, 9 Frum R....Deb S.P. (J. Proteome Res. 2007)
    10. A Proteomics Strategy for the Identification of FAT10-Modified Sites by Mass Spectrometry. (PubMed id 23862649)1 Leng L....Wang J. (J. Proteome Res. 2014)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6224 HGNC: 10405 AceView: RPS20 Ensembl:ENSG00000008988 euGenes: HUgn6224
    ECgene: RPS20 Kegg: 6224 H-InvDB: RPS20

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RPS20 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPS20 gene:
    Search GeneIP for patents involving RPS20

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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