Aliases for RPS2 Gene
Aliases for RPS2 Gene
External Ids for RPS2 Gene
- HGNC: 10404
- Entrez Gene: 6187
- Ensembl: ENSG00000140988
- OMIM: 603624
- UniProtKB: P15880
Previous GeneCards Identifiers for RPS2 Gene
- GC16M002029
- GC16M001952
- GC16M002012
- GC16M001967
- GC16M001975
- GC16M001983
- GC16M002007
- GC16M002045
- GC16M002056
- GC16M002066
Summaries for RPS2 Gene
-
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S5P family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with mouse LLRep3. It is co-transcribed with the small nucleolar RNA gene U64, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
GeneCards Summary for RPS2 Gene
RPS2 (Ribosomal Protein S2) is a Protein Coding gene. Diseases associated with RPS2 include Diamond-Blackfan Anemia. Among its related pathways are Viral mRNA Translation and Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S. Gene Ontology (GO) annotations related to this gene include enzyme binding.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPS2 Gene
Genomics for RPS2 Gene
GeneHancer (GH) Regulatory Elements for RPS2 Gene
Promoters and enhancers for RPS2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around RPS2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for RPS2 Gene
Genomic Locations for RPS2 Gene
- chr16:1,962,052-1,964,860
- (GRCh38/hg38)
- Size:
- 2,809 bases
- Orientation:
- Minus strand
- chr16:2,012,053-2,014,861
- (GRCh37/hg19)
Genomic View for RPS2 Gene
Genes around RPS2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p13.3 by Ensembl
- 16p13.3 by Entrez Gene
- 16p13.3 by HGNC
RPS2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RPS2 Gene
Proteins for RPS2 Gene
-
Protein details for RPS2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P15880-RS2_HUMAN
- Recommended name:
- 40S ribosomal protein S2
- Protein Accession:
- P15880
- B2R5G0
- D3DU82
- Q3MIB1
Protein attributes for RPS2 Gene
- Size:
- 293 amino acids
- Molecular mass:
- 31324 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=CAA35078.1; Type=Frameshift; Positions=14, 27, 40, 46, 48, 52; Evidence={ECO:0000305};
Protein Expression for RPS2 Gene
Post-translational modifications for RPS2 Gene
- Asymmetric arginine dimethylation by PRMT3 occurs at multiple sites in the Arg/Gly-rich region.
- Citrullinated by PADI4 in the Arg/Gly-rich region.
- Ubiquitination at isoforms=58, isoforms=65, posLast=114114, isoforms=145, posLast=212212, isoforms=238, posLast=246246, posLast=257257, isoforms=263, and posLast=275275
Other Protein References for RPS2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for RPS2
- Novus Biologicals Antibodies for RPS2
-
Abcam antibodies for RPS2
- Invitrogen Antibodies for RPS2
- GeneTex RPS2 antibody for RPS2
-
Santa Cruz Biotechnology (SCBT) Antibodies for RPS2
Protein Products
-
OriGene Purified Proteins for RPS2
- Search Origene for MassSpec and Protein Over-expression Lysates for RPS2
- Origene Custom Protein Services for RPS2
- ProSpec Recombinant Proteins for RPS2
- Search GeneTex for Proteins for RPS2
-
Abcam proteins for RPS2
Assay Products
No data available for DME Specific Peptides for RPS2 Gene
Domains & Families for RPS2 Gene
Gene Families for RPS2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted intracellular proteins
- Ribosomal proteins
Protein Domains for RPS2 Gene
Suggested Antigen Peptide Sequences for RPS2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P15880- Family:
-
- Belongs to the universal ribosomal protein uS5 family.
Function for RPS2 Gene
Molecular function for RPS2 Gene
- GENATLAS Biochemistry:
- 60S ribosomal protein S2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | HDA,IEA | 22658674 |
| GO:0003729 | mRNA binding | IDA | 18464793 |
| GO:0003735 | structural constituent of ribosome | HDA,IEA | 15883184 |
| GO:0005515 | protein binding | IPI | 15473865 |
| GO:0017134 | fibroblast growth factor binding | IPI | 16263090 |
Phenotypes for RPS2 Gene
- GenomeRNAi human phenotypes for RPS2:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Decreased NF-kappaB reporter expression
- Decreased IL-8 secretion
- Decreased viability
- Increased cell number in S
- Increased cell death HMECs cells
- Synthetic lethal with vaccinia virus (VACV) infection
- Decreased cell number
- Decreased Hepatitis C virus replication
- Decreased DCP1a protein expression and assembly in processing bodies after arsenite stimulation
- Nuclear 40S maturation defects
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for RPS2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for RPS2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RPS2 gene
- Search ViGene Biosciences for RPS2
CRISPR Products
-
OriGene CRISPR knockouts for RPS2
- genomics-online: gRNA clones - Search results for 221 available RPS2 gene related products
- Overview of 221 available RPS2 gene related products
- Applied Biological Materials CRISPR for RPS2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RPS2
- GenScript: Design CRISPR guide RNA sequences for RPS2
miRNA for RPS2 Gene
- miRTarBase miRNAs that target RPS2
-
- hsa-mir-16-5p (MIRT031671)
- hsa-mir-1250-5p (MIRT035864)
- hsa-mir-1301-3p (MIRT036012)
- hsa-mir-940 (MIRT036604)
- hsa-mir-760 (MIRT036761)
- hsa-mir-455-3p (MIRT037900)
- hsa-mir-423-5p (MIRT038055)
- hsa-mir-361-3p (MIRT038274)
- hsa-mir-25-5p (MIRT038957)
- hsa-mir-615-3p (MIRT040163)
- hsa-mir-18a-3p (MIRT040839)
- hsa-mir-423-3p (MIRT042586)
- hsa-mir-324-5p (MIRT043030)
- hsa-mir-331-3p (MIRT043266)
- hsa-mir-328-3p (MIRT043802)
- hsa-mir-330-3p (MIRT043827)
- hsa-mir-361-5p (MIRT044087)
- hsa-mir-99b-5p (MIRT044194)
- hsa-mir-186-5p (MIRT045205)
- hsa-mir-125a-5p (MIRT045736)
- hsa-mir-222-3p (MIRT046672)
- hsa-mir-34a-5p (MIRT047364)
- hsa-mir-196a-5p (MIRT048173)
- hsa-mir-22-3p (MIRT050452)
- hsa-mir-3943 (MIRT052895)
miRNA Products
- Search ViGene Biosciences for RPS2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for RPS2
- Browse OriGene Inhibitory RNA Products For RPS2
- genomics-online: shRNA clones - Search results for 221 available RPS2 gene related products
- Overview of 221 available RPS2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for RPS2 gene
Clone Products
- Sino Biological Human cDNA Clone for RPS2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RPS2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RPS2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for RPS2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for RPS2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for RPS2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RPS2 gene
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RPS2 Gene
Localization for RPS2 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 5 |
| mitochondrion | 2 |
| peroxisome | 1 |
- Cytosol (2)
- Endoplasmic reticulum (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA,HDA | 21630459 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005730 | NOT nucleolus | IDA | 16061210 |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005840 | ribosome | IEA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for RPS2 Gene
Pathways & Interactions for RPS2 Gene
Pathways by source for RPS2 Gene
1 BioSystems pathway for RPS2 Gene
1 KEGG pathway for RPS2 Gene
1 GeneGo (Thomson Reuters) pathway for RPS2 Gene
Interacting Proteins for RPS2 Gene
Selected Interacting proteins:
ENSP00000341885
P15880-RS2_HUMAN
for RPS2 Gene via
STRING
IID
UniProtKB
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | -- |
| GO:0006364 | rRNA processing | TAS | -- |
| GO:0006412 | translation | IEA,IC | 8706699 |
| GO:0006413 | translational initiation | TAS | -- |
| GO:0006479 | protein methylation | TAS | -- |
No data available for SIGNOR curated interactions for RPS2 Gene
Drugs & Compounds for RPS2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Copper | Approved, Investigational | Pharma | Target | 202 |
Transcripts for RPS2 Gene
mRNA/cDNA for RPS2 Gene
- (1) REFSEQ mRNAs :
- (40) Additional mRNA sequences :
- (260) Selected AceView cDNA sequences:
- (17) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RPS2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for RPS2
- genomics-online: gRNA clones - Search results for 221 available RPS2 gene related products
- Overview of 221 available RPS2 gene related products
- Applied Biological Materials CRISPR for RPS2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RPS2
- GenScript: Design CRISPR guide RNA sequences for RPS2
miRNA Products
- Search ViGene Biosciences for RPS2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for RPS2
- Browse OriGene Inhibitory RNA Products For RPS2
- genomics-online: shRNA clones - Search results for 221 available RPS2 gene related products
- Overview of 221 available RPS2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for RPS2 gene
Clone Products
- Sino Biological Human cDNA Clone for RPS2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RPS2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RPS2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for RPS2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | · | 1g | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||||||||
| SP9: | - | ||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP11: | - | ||||||||||||||||||||||||||||||||||||||||
| SP12: | - |
Expression for RPS2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- Presumptive Podocytes Podocyte Layer
-
Epithelial Cells
- Presumptive Podocytes Podocyte Layer
- Endoderm (Gastrulation Derivatives)
-
Prostate (Endocrine System)
-
Tonsil (Hematopoietic System)
This gene is overexpressed in Nasal epithelium (6.9) and Tlymphocyte (6.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RPS2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of RPS2 Gene:
RPS2SOURCE GeneReport for Unigene cluster for RPS2 Gene:
Hs.356366Evidence on tissue expression from TISSUES for RPS2 Gene
- Eye(5)
- Intestine(5)
- Liver(5)
- Lung(5)
- Pancreas(5)
- Skin(5)
- Nervous system(5)
- Kidney(4.9)
- Bone(4.8)
- Muscle(4.8)
- Stomach(4.8)
- Blood(4.5)
- Heart(3)
- Spleen(3)
- Lymph node(2.5)
- Bone marrow(2.4)
- Gall bladder(2.2)
- Thyroid gland(2.2)
- Adrenal gland(2.1)
Primer Products
-
OriGene qPCR primer pairs for RPS2
-
OriGene qPCR primer pairs and template standards for RPS2
- genomics-online: primer clones - Search results for 221 available RPS2 gene related products
- Overview of 221 available RPS2 gene related products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RPS2 Gene
Orthologs for RPS2 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RPS2 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Rps2-ps6 34 |
|
OneToOne | |
| Rps2 33 16 |
|
||||
| cow (Bos Taurus) |
Mammalia | RPS2 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | RPS2 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Rps2 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | RPS2 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | RPS2 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | RPS2 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | RPS2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | rps2 33 |
|
||
| Str.6712 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.29155 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | rps2 33 34 |
|
||
| wufb65c08 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.9009 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | sop 35 |
|
|
|
| RpS2 33 34 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP003768 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | rps-2 35 33 34 |
|
||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AAR177W 33 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F09812g 33 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RPS2 33 34 36 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | XW6 33 |
|
||
| Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.7153 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os03g0807800 33 |
|
||
| Os.11049 33 |
|
||||
| barley (Hordeum vulgare) |
Liliopsida | Hv.4103 33 |
|
||
| wheat (Triticum aestivum) |
Liliopsida | Ta.28855 33 |
|
||
| corn (Zea mays) |
Liliopsida | Zm.7140 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.10600 34 |
|
OneToOne | |
| bread mold (Neurospora crassa) |
Ascomycetes | NCU06047 33 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | rps2 33 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.4371 33 |
|
- Species where no ortholog for RPS2 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Paralogs for RPS2 Gene
(4) SIMAP similar genes for RPS2 Gene using alignment to 14 proteins:
Pseudogenes.org Pseudogenes for RPS2 Gene
- PGOHUM00000290547
- PGOHUM00000290692
- PGOHUM00000290835
- PGOHUM00000290848
- PGOHUM00000291466
- PGOHUM00000291565
- PGOHUM00000291632
- PGOHUM00000292408
- PGOHUM00000292412
- PGOHUM00000292445
- PGOHUM00000292457
- PGOHUM00000292679
- PGOHUM00000292727
- PGOHUM00000293347
- PGOHUM00000293604
- PGOHUM00000293616
- PGOHUM00000293894
- PGOHUM00000293984
- PGOHUM00000294088
- PGOHUM00000294089
- PGOHUM00000294141
- PGOHUM00000294156
- PGOHUM00000294288
- PGOHUM00000294819
- PGOHUM00000295162
- PGOHUM00000295205
- PGOHUM00000295225
- PGOHUM00000295651
- PGOHUM00000295674
- PGOHUM00000295693
- PGOHUM00000295795
- PGOHUM00000296273
- PGOHUM00000296287
- PGOHUM00000296292
- PGOHUM00000296322
- PGOHUM00000296616
- PGOHUM00000296626
- PGOHUM00000296713
- PGOHUM00000297014
- PGOHUM00000297109
- PGOHUM00000297817
- PGOHUM00000298495
- PGOHUM00000298839
- PGOHUM00000299250
- PGOHUM00000299807
- PGOHUM00000300002
- PGOHUM00000300017
- PGOHUM00000300719
- PGOHUM00000300934
- PGOHUM00000300974
- PGOHUM00000301024
- PGOHUM00000301044
- PGOHUM00000301352
- PGOHUM00000301359
- PGOHUM00000301784
- PGOHUM00000301799
- PGOHUM00000302084
- PGOHUM00000302552
- PGOHUM00000302915
- PGOHUM00000303313
- PGOHUM00000304007
- PGOHUM00000304348
- PGOHUM00000304564
- PGOHUM00000288265
- PGOHUM00000288266
- PGOHUM00000289968
No data available for Paralogs for RPS2 Gene
Variants for RPS2 Gene
| SNP ID | Clin | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000994330 | -- | 1,963,995(-) | G/A | intron_variant | |
| rs1001008825 | -- | 1,961,652(-) | A/C | downstream_transcript_variant | |
| rs1001274604 | -- | 1,963,822(-) | C/G/T | intron_variant | |
| rs1001537032 | -- | 1,961,599(-) | G/A | downstream_transcript_variant | |
| rs1001591131 | -- | 1,966,634(-) | G/T | upstream_transcript_variant |
Residual Variation Intolerance Score:
35.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.36;
8.03% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RPS2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RPS2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPS2 Gene
Disorders for RPS2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| diamond-blackfan anemia |
|
|
Search RPS2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RPS2
No data available for UniProtKB/Swiss-Prot and Genatlas for RPS2 Gene
Publications for RPS2 Gene
- Ribosomal protein S2 is a substrate for mammalian PRMT3 (protein arginine methyltransferase 3). (PMID: 15473865) Swiercz R … Bedford MT (The Biochemical journal 2005) 3 4 22 58
- Discovery of peptidylarginine deiminase-4 substrates by protein array: antagonistic citrullination and methylation of human ribosomal protein S2. (PMID: 21584310) Guo Q … Fast W (Molecular bioSystems 2011) 3 4 58
- PRMT3 inhibits ubiquitination of ribosomal protein S2 and together forms an active enzyme complex. (PMID: 18573314) Choi S … Im DS (Biochimica et biophysica acta 2008) 3 22 58
- Identification of an unconventional nuclear localization signal in human ribosomal protein S2. (PMID: 16061210) Antoine M … Kiefer P (Biochemical and biophysical research communications 2005) 3 22 58
- Fibroblast growth factor 3, a protein with a dual subcellular fate, is interacting with human ribosomal protein S2. (PMID: 16263090) Antoine M … Kiefer P (Biochemical and biophysical research communications 2005) 3 22 58
Products for RPS2 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
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- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody ServicesOriGene Antibodies for RPS2
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for RPS2
- Search Origene for MassSpec and Protein Over-expression Lysates for RPS2
- Origene Custom Protein Services for RPS2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RPS2
- Browse OriGene Inhibitory RNA Products For RPS2
- OriGene qPCR primer pairs and template standards for RPS2
- OriGene qPCR primer pairs for RPS2
- OriGene CRISPR knockouts for RPS2
- OriGene ORF clones in human for RPS2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RPS2
- GenScript: Next-day shipping of latest version cDNA ORF clones for RPS2 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for RPS2
- GenScript Custom Assay Services for RPS2
- GenScript Custom overexpressing Cell Line Services for RPS2
- GenScript: Design CRISPR guide RNA sequences for RPS2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for RPS2
- Sino Biological Human cDNA Clone for RPS2
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for RPS2
- Novus Biologicals lysates and proteins for RPS2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for RPS2
- Abcam proteins for RPS2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
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- Browse ELISA Kits
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- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
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- ProSpec Recombinant Proteins for RPS2
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for RPS2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for RPS2
- VectorBuilder custom plasmid, inducible vectors for RPS2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RPS2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 39 available RPS2 Antibodies ranked by validation data
- Compare Top RPS2 Antibodies
- antibodies-online: Search results for 12 available RPS2 Elisa Kits ranked by validation data
- Compare Top RPS2 Elisa Kits
- antibodies-online: Search results for 14 available RPS2 Proteins ranked by validation data
- Compare Top RPS2 Proteins
- GeneTex RPS2 antibody for RPS2
- Search GeneTex for Proteins for RPS2
- ViGene Biosciences adenoviral particle packaged cDNA for RPS2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for RPS2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for RPS2 gene
- Search ViGene Biosciences for RPS2
- Santa Cruz Biotechnology (SCBT) Antibodies for RPS2
- Search Santa Cruz Biotechnology (SCBT) for RPS2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RPS2
- genomics-online: cdna clones - Search results for 221 available RPS2 gene related products
- Overview of 221 available RPS2 gene related products
- orf clones - Search results for 221 available RPS2 gene related products
- Overview of 221 available RPS2 gene related products
- genomics-online: gRNA clones - Search results for 221 available RPS2 gene related products
- Overview of 221 available RPS2 gene related products
- genomics-online: primer clones - Search results for 221 available RPS2 gene related products
- Overview of 221 available RPS2 gene related products
- genomics-online: shRNA clones - Search results for 221 available RPS2 gene related products
- Overview of 221 available RPS2 gene related products
Sources for RPS2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42)