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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPS18 Gene

protein-coding   GIFtS: 58
GCID: GC06P033240

Ribosomal Protein S18


(Previous symbol: D6S218E)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ribosomal Protein S181 2     KE32
D6S218E1 2 3     S182
40S Ribosomal Protein S182     Rhabdomyosarcoma Antigen MU-RMS-40.212
HKE32     Ke-33
KE-32     Ke33

External Ids:    HGNC: 104011   Entrez Gene: 62222   Ensembl: ENSG000002315007   OMIM: 1804735   UniProtKB: P622693   

Export aliases for RPS18 gene to outside databases

Previous GC identifers: GC06P033243 GC06P033236 GC06P033232 GC06P033286 GC06P033347 GC06Pf33317 GC06P032981


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RPS18 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S13P family
of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal
protein S13) is involved in the binding of fMet-tRNA, and thus, in the initiation of translation. This gene is an
ortholog of mouse Ke3. As is typical for genes encoding ribosomal proteins, there are multiple processed
pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPS18 Gene: 
RPS18 (ribosomal protein S18) is a protein-coding gene. Diseases associated with RPS18 include bowen-conradi syndrome, and pasteurellosis, and among its related super-pathways are Eukaryotic Translation Initiation and Formation of the ternary complex, and subsequently, the 43S complex. GO annotations related to this gene include rRNA binding and molecular_function.

UniProtKB/Swiss-Prot: RS18_HUMAN, P62269
Function: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA (By
similarity)

Gene Wiki entry for RPS18 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007592.15  NT_113891.2  NT_167245.1  NT_167247.1  NT_167248.1  NT_167249.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPS18 gene promoter:
         ER-alpha   TBP   p53   AP-1   Olf-1   Meis-1b   PPAR-alpha   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS18 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPS18

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.32   HGNC cytogenetic band: 6p21.3

RPS18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS18 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P033240:  view genomic region     (about GC identifiers)

Start:
33,239,787 bp from pter      End:
33,244,287 bp from pter
Size:
4,501 bases      Orientation:
plus strand

5 alternative locations:
Chr6+,NT_167249 4,720,054-4,720,712      Chr6+,NT_113891.2 4,683,662-4,688,091      Chr6+,NT_167248 4,472,088-4,476,520     
Chr6+,NT_167245 4,521,174-4,525,603      Chr6+,NT_167247 4,713,622-4,718,055     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RS18_HUMAN, P62269 (See protein sequence)
Recommended Name: 40S ribosomal protein S18  
Size: 152 amino acids; 17719 Da
Subcellular location: Cytoplasm
1 PDB 3D structure from and Proteopedia for RPS18:
3J3A (3D)    
Secondary accessions: P25232 Q5SUJ3 Q6IPF8

Explore the universe of human proteins at neXtProt for RPS18: NX_P62269

Explore proteomics data for RPS18 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P62269

  • RPS18 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RPS18 Protein Expression
    REFSEQ proteins: NP_072045.1  
    ENSEMBL proteins: 
     ENSP00000393241   ENSP00000434837  
    Reactome Protein details: P62269
    Human Recombinant Protein Products for RPS18: 
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    Cloud-Clone Corp. Proteins for RPS18 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005581collagen ----
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--
    GO:0005840ribosome NAS8441687
    GO:0015935small ribosomal subunit IDA15883184

    RPS18 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RPS: S ribosomal proteins

    4 InterPro protein domains:
     IPR027437 30s_Rbsml_prot_S13_C
     IPR010979 Ribosomal_S13-like_H2TH
     IPR001892 Ribosomal_S13
     IPR018269 Ribosomal_S13_CS

    Graphical View of Domain Structure for InterPro Entry P62269

    ProtoNet protein and cluster: P62269

    UniProtKB/Swiss-Prot: RS18_HUMAN, P62269
    Similarity: Belongs to the ribosomal protein S13P family


    RPS18 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RS18_HUMAN, P62269
    Function: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA (By
    similarity)

         Genatlas biochemistry entry for RPS18:
    40S ribosomal protein S18,17kDa

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding ----
    GO:0003735structural constituent of ribosome IBA--
    GO:0005515protein binding ----
         
    RPS18 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for RPS18:
     Decreased Hepatitis C virus re  Increased S DNA content  Increased number of cells in m 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rps18):
     normal 

    RPS18 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RPS18 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPS18 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RPS18 About   (see all 6)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Viral mRNA Translation
    Influenza Life Cycle0.95
    3' -UTR-mediated translational regulation0.93
    Influenza Infection0.95
    L13a-mediated translational silencing of Ceruloplasmin expression0.93
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Formation of a pool of free 40S subunits0.90
    Eukaryotic Translation Termination0.94
    Nonsense-Mediated Decay0.84
    2Translation initiation complex formation
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.95
    Formation of the ternary complex, and subsequently, the 43S complex0.87
    Ribosomal scanning and start codon recognition0.95
    Translation initiation complex formation0.87
    3Metabolism of mRNA
    Metabolism of mRNA0.92
    Metabolism of RNA0.92
    4Generic Transcription Pathway
    Gene Expression0.47
    5Asparagine N-linked glycosylation
    Metabolism of proteins0.35

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS18
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS18
        Cytoplasmic Ribosomal Proteins

    5/27        Reactome Pathways for RPS18 (see all 27)
        Formation of the ternary complex, and subsequently, the 43S complex
    Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane


    1         Kegg Pathway  (Kegg details for RPS18):
        Ribosome


    RPS18 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPS18

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/830 Interacting proteins for RPS18 (P622692, 3 ENSP000003932414) via UniProtKB, MINT, STRING, and/or I2D (see all 830)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPS3P233962, 3, ENSP000002785724MINT-7945693 I2D: score=4 STRING: ENSP00000278572
    KPNA2P522922, 3MINT-7945693 I2D: score=3 
    RPL8P629172, 3MINT-7945693 I2D: score=3 
    RPS17LP0CW222, 3MINT-8395092 I2D: score=3 
    RPS2P158802, 3MINT-6541718 I2D: score=3 
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPS18 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPS18 (RS18)

    Search CenterWatch for drugs/clinical trials and news about RPS18 / RS18

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPS18 gene: 
    NM_022551.2  

    Unigene Clusters for RPS18:

    Ribosomal protein S18
    Hs.448854  [show with all ESTs], Hs.627414  [show with all ESTs]
    Unigene Representative Sequences: BM807407, BM455098
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000439602(uc003odp.1) ENST00000474973 ENST00000474626 ENST00000476222(uc010jum.1)
    ENST00000496813 ENST00000490191 ENST00000472218 ENST00000479802
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS18
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS18

    Additional mRNA sequence: 

    AY536376.1 BC101786.1 BC101788.1 BC106063.1 X69150.1 

    24/89 DOTS entries (see all 89):

    DT.91998585  DT.95377286  DT.100740961  DT.95344519  DT.100740939  DT.100060011  DT.91834101  DT.86996684 
    DT.91814620  DT.120845911  DT.100740909  DT.100740951  DT.91998593  DT.100837312  DT.95376793  DT.97845755 
    DT.121308046  DT.95376571  DT.100740954  DT.421008  DT.95377868  DT.121307918  DT.121308042  DT.95376911 

    24/2732 AceView cDNA sequences (see all 2732):

    BM766209 AW188446 AI890543 BQ676420 BM423845 AA314403 BG576754 AW167536 
    AA360158 AA968842 BU627674 BX393457 AA196251 BM808309 BG108052 BU517063 
    BQ052125 BU174236 BM479799 AA311330 AA353086 AI523510 BM745371 BM740205 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPS18 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGTGTTGAG
    RPS18 Expression
    About this image


    See RPS18 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPS18

    SOURCE GeneReport for Unigene clusters: Hs.448854 Hs.627414
        SABiosciences Custom PCR Arrays for RPS18
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS18

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS18 gene from 8/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rps181 , 5 ribosomal protein S181, 5 91.89(n)1
    100(a)1
      17 (17.98 cM)5
    200841  NM_011296.21  NP_035426.11 
     339519995 
    lizard
    (Anolis carolinensis)
    Reptilia RPS186
    Uncharacterized protein
    99(a)
    1 ↔ 1
    GL343857.1(4617-12076)
    zebrafish
    (Danio rerio)
    Actinopterygii rps181 ribosomal protein S18 81.58(n)
    98.03(a)
      192300  NM_173234.1  NP_775341.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpS181 , 3 protein biosynthesis structural
    constituent of more3
    Ribosomal protein S181
    74(a)3
    72.37(n)1
    77.63(a)1
      56F133
    372921  NM_057616.51  NP_476964.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rps-181 , 3 ribosomal protein S133
    Protein RPS-181
    76(a)3
    70.61(n)1
    76.32(a)1
      IV(14825803-14826578)3
    1784081  NM_070393.31  NP_502794.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPS18B1 Rps18bp 64.55(n)
    71.83(a)
      854982   NP_013686.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons PFL1 40S ribosomal protein S18 70.18(n)
    74.34(a)
      838884  NM_102125.3  NP_173692.1 
    rice
    (Oryza sativa)
    Liliopsida Os07g01737001 hypothetical protein 68.64(n)
    71.71(a)
      4342526  NM_001065542.2  NP_001059007.2 


    ENSEMBL Gene Tree for RPS18 (if available)
    TreeFam Gene Tree for RPS18 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/36 SNPs in RPS18 are shown (see all 36)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs775372931,2
    C--33241675(+) TTAATA/TAATAA 1 -- int10--------
    rs92824851,2
    C--33241682(+) TAAAT-/AAAT  
            
    TTGAA
    1 -- int10--------
    rs105399521,2
    C--33241737(+) TCATG-/TTTA  
            
    TTTAT
    1 -- int10--------
    rs1806795581,2
    --33241740(+) TGTTTA/GTTTAT 1 -- int10--------
    rs1852528691,2
    --33241797(+) TGGTGC/TAATCT 1 -- int10--------
    rs1402696551,2
    --33241806(+) CTTATC/GTCACT 1 -- int10--------
    rs100809291,2
    C--33241851(+) gcacaC/Tgccca 1 -- int10--------
    rs1813117631,2
    --33241922(+) ACTTCC/TGACCT 1 -- int10--------
    rs1503543331,2
    C--33242361(+) CTTGGC/TGCTGG 1 -- int10--------
    rs1474914031,2
    C--33242491(+) TCGTG-/TCTCTCT 1 -- int10--------

    HapMap Linkage Disequilibrium report for RPS18 (33239787 - 33244287 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RPS18:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv830634CNV Loss17160897
    nsv830635CNV Loss17160897
    nsv5249CNV Loss18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 180473    OMIM disorders: --

    11 diseases for RPS18:    About MalaCards
    bowen-conradi syndrome    pasteurellosis    rhabdomyosarcoma    fanconi's anemia
    anemia    influenza    systemic lupus erythematosus    lupus erythematosus
    prostate cancer    prostatitis    breast cancer

    1 disease from the University of Copenhagen DISEASES database for RPS18:
    Bowen-Conradi syndrome

    RPS18 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RPS18
    Human Genome Epidemiology (HuGE) Navigator: RPS18 (3 documents)

    Export disorders for RPS18 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPS18 gene, integrated from 9 sources (see all 70):
    (articles sorted by number of sources associating them with RPS18)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human homolog of ribosomal protein S18. (PubMed id 8441687)1, 2, 3, 9 Chassin D.... Koman A. (1993)
    2. Sequential use of transcriptional profiling, expressi on quantitative trait mapping, and gene association implicates MMP20 in human k idney aging. (PubMed id 19834535)1, 4 Wheeler H.E....Kim S.K. (2009)
    3. High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1, 4 Barcellos L.F....Criswell L.A. (2009)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    5. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 3 Kenmochi N.... Page D.C. (1998)
    6. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (1996)
    7. Ribosomal protein S18 identified as a cofilin-binding protein by using phage display library. (PubMed id 15532723)1, 9 Kusui K....Suzuki K. (2004)
    8. The S18 ribosomal protein is a putative substrate for Ca2+/calmodulin-activated protein kinase II. (PubMed id 12145273)1, 9 Mishra-Gorur K....Castellot J.J. (2002)
    9. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....Yanez-Mo M. (2013)
    10. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6222 HGNC: 10401 AceView: B3GALT4andRPS18andD6S2723E Ensembl:ENSG00000231500 euGenes: HUgn6222
    ECgene: RPS18 Kegg: 6222 H-InvDB: RPS18

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPS18 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPS18 gene:
    Search GeneIP for patents involving RPS18

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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