RPS17L Gene
protein-coding GIFtS: 39
GCID: GC15M083202
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ribosomal protein S17-like
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Aliases
for RPS17L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ribosomal Protein S17-Like1 2 | | 40S Ribosomal Protein S17-Like2 |
Export aliases for RPS17L gene to outside databases |
Summaries
for RPS17L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for RPS17L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_077661.3
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for RPS17L
Other transcription factors
Search SABiosciences Chromatin IP Primers for RPS17L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS17L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Ensembl cytogenetic band: 15q25.2 HGNC cytogenetic band: 15q25.2RPS17L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M083202: view genomic region
(about GC identifiers)
Start:
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83,201,932 bp from pter |
End:
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83,210,007 bp from pter |
Size:
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8,076 bases |
Orientation:
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minus strand |
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Proteins
for RPS17L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RS17L_HUMAN, P0CW22 (See
protein sequence)Recommended Name: 40S ribosomal protein S17-like Size: 135 amino acids; 15550 DaExplore the universe of human proteins at neXtProt for RPS17L: NX_P0CW22
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P0CW22
RPS17L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001185986.1
ENSEMBL proteins: ENSP00000346046 ENSP00000453910 ENSP00000452889 ENSP00000453894
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
RPS17L for ontologies About GeneDecksing
RPS17L Antibody Products:
Assay Products for RPS17L: |
Protein
Domains /
Families
for RPS17L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RPS17L for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P0CW22ProtoNet protein and cluster: P0CW22 UniProtKB/Swiss-Prot: RS17L_HUMAN, P0CW22Similarity: Belongs to the ribosomal protein S17e family |
Function
for RPS17L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003735 | structural constituent of ribosome |
IEA | -- |
RPS17L for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for RPS17L:
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Pathways & Interactions
for RPS17L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table 
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Synthesis of PB1-F2 | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for RPS17L
1 
Kegg Pathway (Kegg details for RPS17L):
RPS17L for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPS17L
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/229 Interacting proteins for RPS17L (P0CW222, 3 ENSP000003460464) via UniProtKB, MINT, STRING, and/or I2D (see all 229)About this table
Gene Ontology (GO): 5/17 biological process terms (GO ID links to tree view) (see all 17): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000028 | ribosomal small subunit assembly |
-- | -- | | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
-- | -- | | GO:0006364 | rRNA processing |
-- | -- | | GO:0006412 | translation |
IEA | -- | | GO:0006413 | translational initiation |
-- | -- |
RPS17L for ontologies About GeneDecksing
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Drugs & Compounds
for RPS17L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RPS17L
Search CenterWatch for drugs/clinical trials and news about RPS17L / RS17L
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Transcripts
for RPS17L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RPS17L gene: NM_001199057.1 Unigene Cluster for RPS17L: Ribosomal protein S17-like Hs.433427 [show with all ESTs]Unigene Representative Sequence: BM91875210 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000330244(uc002bio.1) ENST00000560229 ENST00000561157 ENST00000558397
ENST00000561068 ENST00000560612 ENST00000561440 ENST00000560639 ENST00000559776
ENST00000559273
Additional cDNA sequence: AK311951.1 BC009407.2 BC019899.1 BC020453.1 BC022370.1 BC049824.1 BC062715.1 BC070222.1 BC071928.1 M13932.1 24/69 DOTS entries (see all 69): DT.95231387 DT.95378808 DT.98081977 DT.100060125 DT.92469637 DT.100739925 DT.100638918 DT.92469644 DT.92469626 DT.92469622 DT.121021573 DT.100739953 DT.100739968 DT.121021874 DT.100739938 DT.91869254 DT.100876268 DT.91651851 DT.100868623 DT.95252543 DT.121022024 DT.100739912 DT.121021845 DT.100739963
GeneLoc Exon Structure
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Expression
for RPS17L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RPS17L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See RPS17L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RPS17L
SOURCE GeneReport for Unigene cluster: Hs.433427
SABiosciences Custom PCR Arrays for RPS17L
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat RPS17L | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS17L | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS17L |
Orthologs
for RPS17L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of eukaryotes.
Orthologs for RPS17L gene from 8/31 species (see all 31) About this table
ENSEMBL Gene Tree for RPS17L (if available)
TreeFam Gene Tree for RPS17L (if available) |
Paralogs
for RPS17L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RPS17L gene
- RPS171 2
2 SIMAP similar genes for RPS17L using alignment to 3 protein entries: RS17L_HUMAN (see all proteins):RPS17 LOC392101
RPS17L for paralogs About GeneDecksing
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Genomic Variants
for RPS17L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RPS17L (83201932 - 83210007 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for RPS17L: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPS17L |
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Disorders
/ Diseases
for RPS17L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RPS17L for disorders About GeneDecksing
1  disease for RPS17L: About MalaCardsmalaria
Export disorders for RPS17L gene to outside databases
|
Publications
for RPS17L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RPS17L gene integrated from 9 sources:
(articles sorted by number of sources associating them with RPS17L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)
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External Searches for RPS17L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing RPS17L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RPS17L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RPS17L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
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About This Section
| Patent Information for RPS17L gene:
Search GeneIP for patents involving RPS17L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RPS17L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RPS17L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPS17L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS17L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS17L | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS17L | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS17L |
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| | | | Search Tocris compounds for RPS17L |
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 | | | RPS17L Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for RPS17L |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RPS17L |
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