Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Explore sets of GeneCards genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RPS17 Gene

protein-coding GIFtS: 61
GCID: GC15M082821

ribosomal protein S17

Explore 13 diseases affiliated with
RPS17 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ribosomal Protein S17¹ ²		DBA4² ⁵
RPS17L1¹ ² ⁵		MGC72007¹
RPS17L2¹ ² ⁵		40S Ribosomal Protein S17²
S17¹ ²		RPS17L²

External Ids:	HGNC: 10397¹	Entrez Gene: 6218²	Ensembl: ENSG00000184779⁷	OMIM: 180472⁵	UniProtKB: P08708³

Export aliases for RPS17 gene to outside databases

Previous GC identifers: GC15M079008 GC15M076138 GC15M080395 GC15M080536 GC15M080608 GC15M059476

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RPS17:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.

Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene

encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17E family of

ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are

multiple processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

Gene Wiki entry for RPS17

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RPS17 gene promoter:
COUP-TF1 COUP HNF-4alpha2 E4BP4 HNF-4alpha1 HNF-1A S8 COUP-TF HNF-1 RSRFC4
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RPS17 promoter sequence

Search SABiosciences Chromatin IP Primers for RPS17

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS17

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q Ensembl cytogenetic band: 15q25.2 HGNC cytogenetic band: 15q

RPS17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS17 gene location

GeneLoc information about chromosome 15 GeneLoc Exon Structure

GeneLoc location for GC15M082821: view genomic region (about GC identifiers)

Start:	82,821,158 bp from pter	End:	82,824,972 bp from pter
Size:	3,815 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RS17_HUMAN, P08708 (See protein sequence)

Recommended Name: 40S ribosomal protein S17

Size: 135 amino acids; 15550 Da

Secondary accessions: B2R4U4

Explore the universe of human proteins at neXtProt for RPS17: NX_P08708

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P08708

RPS17 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_001012.1

ENSEMBL proteins:

ENSP00000346045 ENSP00000453564 ENSP00000452655 ENSP00000452696

Reactome Protein details: P08708
Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for RPS17
	GenScript Custom Purified and Recombinant Proteins Services for RPS17
	Novus Biologicals RPS17 Proteins
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for RPS17

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005829	cytosol	TAS	--
GO:0005840	ribosome	NAS	3240863
GO:0022627	cytosolic small ribosomal subunit	ISS	--

RPS17 for ontologies About GeneDecksing

RPS17 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for RPS17
	GenScript Custom Superior Antibodies Services for RPS17
	Novus Biologicals RPS17 Antibodies
	Search for Antibodies for RPS17 at Abcam
	Uscn Antibodies for RPS17
	Search ThermoFisher Antibodies for RPS17

Assay Products for RPS17:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for RPS17
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for RPS17

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RPS17 for domains About GeneDecksing

2 InterPro domains/families:

IPR018273 Ribosomal_S17e_CS

IPR001210 Ribosomal_S17e

Graphical View of Domain Structure for InterPro Entry P08708

ProtoNet protein and cluster: P08708

1 Blocks protein family: IPB001210 Ribosomal protein S17e

UniProtKB/Swiss-Prot: RS17_HUMAN, P08708

Similarity: Belongs to the ribosomal protein S17e family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

Genatlas biochemistry entry for RPS17:

40S ribosomal protein S17,15kDa

miRNA Products:		OriGene 3'-UTR Clone: RPS17 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPS17
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate RPS17
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS17 (see all 7) OriGene shRNA RFP: RPS17 OriGene siRNA: RPS17
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS17

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for RPS17

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPS17 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPS17 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RPS17 (NM_001021)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPS17
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS17

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for RPS17
		Search LifeMap BioReagents cell lines for RPS17

In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS17

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003735	structural constituent of ribosome	NAS	17647292

RPS17 for ontologies About GeneDecksing

4 GenomeRNAi human phenotypes for RPS17:

Cytoplasmic 40S maturation def

Decreased viability

Increased S DNA content

Nucleolar pre-40S maturation d

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

1

Synthesis of PB1-F2

	8/26 pathways (see all 26)
	Viral Protein Synthesis	1.00			Cytoplasmic Ribosomal Proteins	0.86
	Viral mRNA Translation	1.00			CFTR translational fidelity (class I mutations)	0.83
	Influenza Viral RNA Transcription and Replication	1.00			SMG6 Cleaves mRNA with Premature Termination Codon	0.80
	Synthesis of nascent polypeptide containing signal sequence	1.00			L13a-mediated translational silencing of Ceruloplasmin expression	0.79

2

Translation initiation complex formation

	Translation initiation complex formation	1.00			Ribosomal scanning and start codon recognition	0.96
	Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	0.98			Formation of the ternary complex, and subsequently, the 43S complex	0.87

3

Metabolism of mRNA

Metabolism of mRNA

1.00

Metabolism of RNA

0.92

4

Disease

1.00

5

Generic Transcription Pathway

Gene Expression

0.46

Pathway sources
See GeneCards unified pathways
Show all pathways

1 GeneGo (Thomson Reuters) Pathway for RPS17

CFTR translational fidelity (class I mutations)

1 BioSystems Pathway for RPS17

Cytoplasmic Ribosomal Proteins

5/32 Reactome Pathways for RPS17 (see all 32)

	Formation of a pool of free 40S subunits
	Synthesis of PB1-F2
	SMG6 Cleaves mRNA with Premature Termination Codon
	Influenza Life Cycle
	Viral mRNA Translation

1 Kegg Pathway (Kegg details for RPS17):

RPS17 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RPS17

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/258 Interacting proteins for RPS17 (P08708^{2, 3} ENSP00000346045⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 258)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RPS16	P62249²^,³, ENSP00000251453⁴	MINT-8044024 I2D: score=1 STRING: ENSP00000251453
MAP3K14	Q99558²^,³	MINT-48887 I2D: score=2
RPS26	P62854²^,³	MINT-8044024 I2D: score=1
RPL17	P18621³, ENSP00000389465⁴	I2D: score=1 STRING: ENSP00000389465
RPS14	P62263²^,³, ENSP00000311028⁴	MINT-8044024 I2D: score=2 STRING: ENSP00000311028

About this table

Gene Ontology (GO): 5/17 biological process terms (GO ID links to tree view) (see all 17): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000028	ribosomal small subunit assembly	ISS	--
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	TAS	--
GO:0006364	rRNA processing	IMP	18697920
GO:0006412	translation	TAS	--
GO:0006413	translational initiation	TAS	--

RPS17 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RPS17
Search CenterWatch for drugs/clinical trials and news about RPS17 / RS17

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RPS17 gene:

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000330339(uc002bhr.1 uc021ssu.1) ENST00000560151 ENST00000559187

ENST00000560826 ENST00000560977 ENST00000559636 ENST00000560084 ENST00000560652

ENST00000559854 ENST00000560024

miRNA Products:		OriGene 3'-UTR Clone: RPS17 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPS17
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate RPS17
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS17 (see all 7) OriGene shRNA RFP: RPS17 OriGene siRNA: RPS17
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS17

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPS17 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPS17 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RPS17 (NM_001021)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPS17
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS17

Primer Products:		Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RPS17
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS17
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS17

2925 AceView cDNA sequences (see top 24):

BF475644 BM841150 BG824782 BE391134 BQ678752 F27701 BQ675511 BE277421

BQ954838 BQ130567 AW512342 BM760477 BQ942781 AA135090 AA852123 BG472362

BE295330 BU175479 BM051340 BG818710 BM512300 BM772297 BQ949090 BE256535

BF219696 BE385915 BQ894297 BG341437 BQ691933 BQ954231 W81391 BQ054079

CB114289 CD675690 AL524753 BM760610 AJ713354 BF974836 BQ685965 F19463

AA159814 BE394814 BE796626 BE905890 F22298 BG478350 BU848870 BX374654

CB143996 BG827275 BE873949 BG478391 BF794386 BU163779 BE407171 BG489964

BU931914 BE902756 BG333219 AW081847 BE383859 BG755337 AA372872 BE384845

BF182785 BQ069053 BM841504 BE256639 BE280040 BM424194 BX391083 AA321583

CN484678 BE796548 BQ933150 BQ939557 BG756848 AV655759 BE277953 AI658674

BM450191 AI826436 BE881893 AW768245 BQ687303 BQ130821 BE563749 AI431296

AI688985 CR602312 BF976176 BG684735 BG025346 BC009407 AI419450 BF683784

AI499430 T58433 BQ962750 CA389959 CD673686 BQ669873 BI335815 W44918

BE273502 BQ421161 BG110526 F32131 BG753758 BI599988 BF036643 AJ712486

BE302689 AA687779 BF128903 BF664393 BG685640 BQ420566 BU160699 BU185890

NM_001021 BM550456 BM841177 BU943511 BQ924757 CB130753 BQ653023 AW732814

N95257 CK905078 BU150079 BQ228784 BM785473 BG756701 BM913147 BU165544

BU789620 CB140079 AL515643 BQ073769 BQ787506 BE394739 AV701678 BG341413

BM762335 BF568214 BE407286 BE301795 BM661881 AA612897 BU856594 BG758081

BU159247 BM011083 BG769006 F35128 BF205868 BM911798 BQ880115 BE906991

BM801762 CB133148 BG827693 BF971774 BG331698 BM830301 BE258343 BM552555

BQ954027 BM841857 BM764388 CB117997 BM809315 BU176015 BM841024 BG489554

BM852080 BG755484 BG829929 BM761761 BE729559 BQ926152 BM990526 BU540718

BU789551 BU190372 BG283491 AW117871 BM766970 AI707578 BQ688569 BQ898885

BX349453 CF619103 CN483079 AW105259 BM760628 BG755344 BG490110 CB109597

F35543 BM556569 BM841739 BG478307 BU153629 BI333948 BU737909 BE903086

AI685870 CR618328 F30937 BG116104 CB142512 CD675171 BF309430 BM759105

AV655777 BG760610 AV712492 BE276321 BM841260 BG774758 BG248398 AW732811

BQ942805 AA327346 BC071928 BG437682 BE742486 BQ954229 BM008726 BU855666

BQ425599 BU154735 BQ279030 BG398455 F25924 BQ680766 BU522020 AI199060

BM700111 BU529097 CB117969 CD679476 BE295613 BM740689 AJ713878 AA308283

BU781597 BQ877894 BF663470 CR616208 AA329450 BQ952653 AI431617 F21567

AW675793 BG330942 AA468610 F35607 BM840591 BG683278 BG754429 BM010080

F26786 BE294653 BM693718 BQ927052 AA343969 BG754334 AA339981 BU179425

BM773282 CR595559 BQ918714 BQ683592 BC049824 BU190528 BE298525 CR609691

CN484802 BI493340 BM012797 BI195741 BU948228 BE311589 BM755562 BG757851

AA661584 BM465031 AA296571 BU152848 AA583102 AJ710727 AA303775 BM760276

BQ681767 BC062715 BE389686 BE294800 BG338952 BC020453 BQ231150 BF794220

BE901795 BG767794 BE257074 AA112000 BU175826 CB109632 AA187482 BQ684363

AA357036 BG829894 BU930906 BQ876958 BI857211 BG757919 BM787368 CB109224

AW160429 BQ051596 CD105907 BI197301 BI254651 AW602582 CB155166 BM888403

T54312 CB265752 BE312108 BE296099 BG025256 BI194360 CD105295 BG422230

BE893362 BM788251 BQ070359 AW163296 BF795910 BE901871 BM853852 BF727297

CB113570 BE266126 AI685465 BE250270 BM845597 AJ714240 BM853425 AW850714

BM761843 BG684073 BQ436185 BE273924 BM788133 CR615408 BI083853 BU071413

BF206114 BG756563 AA301936 CD107662 AW732907 CB117446 BE263207 F26559

BP429843 AA181031 BQ949354 AW085555 BG758868 BM856092 BE256918 BQ899097

BU162681 CB121816 AI770149 BM907968 BU177959 BM008913 BQ640191 AA984956

BG436757 BM760606 BE276653 BQ682981 CF129105 AI804322 AI685482 CR612555

BM841490 BG686856 BF663516 BQ072200 BM809670 BQ688164 BQ636665 BU859235

BG477805 BM556313 BF683781 BM773168 BQ440363 AA301001 BG490655 AW088896

N29382 AA306145 BG686915 BC019899 BU789131 BE386715 BE279484 BF663531

BU854822 BU164064 BE389594 BG335765 BE390384 BU787660 BG756255 CB111704

BU687786 AJ713716 BF973254 BM557192 BQ679779 BE389882 BU153351 BE270134

BG281205 BG397571 F24193 AI826747 AA583869 BM551200 BG770424 BG754205

BG164256 BQ959691 CR618357 AI818016 BM918016 BQ949434 AA371531 BG291467

AI424764 BE407190 BU845076 BE018962 BQ682440 BM841531 AW197160 AW327844

BE259635 BQ689486 AA100259 BE277510 BQ961732 CB117222 BU539343 BG291221

BM840206 BG756588 BG769557 BQ278109 AA102562 BQ653100 BF307509 BG542472

BE251759 BF975864 BM552902 AA378477 BE255327 CA455386 BF685207 CD522366

BQ278062 BQ054525 H87125 BQ066007 BE274112 BQ053299 BU071649 BM555561

F30874 BG335017 AA342566 BE785152 AW673473 BM840462 BF663979 BG397456

BM048682 BU860449 BG326673 BM017772 BI859473 BP428631 AW160442 BQ681405

BM810049 BM760547 BM018342 BX328900 BG340825 BI085304 BG754291 BQ272361

BG473849 BM511068 BQ918461 AA307349 F36590 AJ712029 BG335377 BM554422

BF313437 BG775064 BM555152 BG756791 BM466987 AW081654 BM010142 AI350773

BM010554 BG756397 BG489798 BE562876 BE901664 BG334741 BF207149 BG758588

BE300493 BQ708048 BM555661 BF976378 BE292859 BG757163 BU851971 BG611033

BE898701 BM503932 BE736000 BQ069684 BQ061975 BG759476 AA659658 BF689560

AI810776 F29135 BE255559 BG942210 BQ065179 BM810092 BG398494 BM852154

BG821401 BG751102 BQ681769 BG034163 BE900873 AJ714639 BI908397 BQ934104

BE263126 BE385936 BQ217535 BG825536 BM046083 AI735507 BG757749 AI680658

BG474935 CB109921 BG475141 BE312748 BI093437 BM008925 BM554008 BG329936

BQ055989 BG034521 F19712 BE122688 CB117869 BE388873 BG766562 AL521076

BF974597 BG333270 BF973334 BM841510 BF237834 BM018499 BU956083 F21551

AJ712718 BM762196 BU070248 AA311396 AA983365 BG424366 BF976505 BQ063805

BQ681396 BG325476 CB113723 AA948615 BU957748 BF726720 CA429344 BG758998

BU596684 BM807840 BM005961 BG165435 BF973282 AJ711771 BQ231122 BQ427515

BE727679 D55968 BM753369 BG337565 CB111047 BG326770 BE298590 BG337279

AA303168 AA878909 BM841038 AA301217 BG766591 BG333352 AW163781 AI608900

BG106379 AI708984 BQ896939 BI196669 AW409751 BG684124 BG489334 BG758908

BQ065403 BE208599 BM840451 AI708569 BU535657 BI870248 CA433901 BG323238

BM808020 BQ881810 BE265586 BE275053 BG746700 BG420666 BG828796 BG574037

BM020391 BQ054661 BQ069565 BM808057 BE734134 BQ654186 BU190339 CB962148

BU849181 BG104203 BG927244 BG767356 AA298999 T53719 CA435235 BF972867

BQ052363 AI459954 BI195124 AA071281 BM921761 BE300834 BE258261 BQ953670

BM551050 BE727434 BF242996 BM555527 BU859736 BE295553 CD246250 BM555031

BC070222 BF663048 CD679343 BG756206 AW304109 BM309972 BI160494 AA630909

BG755155 AW084974 BM558668 BU566650 BQ644189 BU789392 BG759393 BU543434

BG761618 BG757428 AI597709 AJ713103 BG758564 N67157 BM457623 BQ958464

T58552 BG828675 BF976668 BG491542 BM272638 BQ574504 BM423330 BQ054353

AI817447 BE727522 BM908496 BG331463 BE901350 AA362888 BM560825 F21529

BF026354 CA437580 AA736729 BU526832 BX368819 BU839207 BM928525 CB151700

BQ065166 AI750098 BM913310 BM788186 BQ278773 CK905079 BQ051336 BM695414

BG396908 BG759203 BU590077 AA384323 BM745059 BG569794 BU854804 BQ066681

D55840 AA587838 CF128718 BP429394 BF975719 BM009285 F28040 BE898504

CD108689 BU956995 BF128853 AA953119 BF311944 BM807363 AA971055 BG768386

BQ063926 AI186345 BE745402 BG490342 BQ267754 BF036653 BQ710119 BI115960

AA329031 BQ058468 F21337 BU538434 BG757936 BM841867 AA341719 BE313857

BE879710 AJ714331 BU156691 BE539971 BG332977 BU556540 BG765495 AW337471

BI197328 BG686516 BF975087 CD106144 BG770812 BU538730 BQ957202 BM782494

BM043913 BQ927542 BI597659 BQ672000 AA976919 BG490049 BQ064159 BM558988

AA159813 BE388842 AA352594 AU126765 AA310854 BM470159 CB151910 BE788965

F29679 BQ883260 CF129969 BQ063586 BM510078 BX473833 BM553165 BE252851

BF313728 AA973865 BF686695 BG150791 BQ054619 BG821599 CB050421 BQ682156

BG758147 BF972285 BP870711 BM915222 BU196562 BM310251 BU188798 AI082373

BU943496 BE257065 BG753934 BM551244 BG425369 BG686154 AW470620 BU543122

AA335716 BF975104 AA302289 AI633417 BG753491 BU850069 BE294076 BG490373

BE255563 BG336310 BG758750 BU856306 BM562763 BQ940122 BG758341 BG774259

BE730777 BI858412 BQ055404 BU538768 AJ706428 BM560981 CB150961 BE267794

AA877739 BU856901 AI597666 AA186422 AA643097 BU685124 AA887137 BU948497

AI027836 BM916009 BG425162 CB109504 BU956346 BI861650 BF685585 BG424015

CB107283 BE252572 BM559597 BM556040 AA315471 BF976128 BM008791 BQ051543

BF974429 BG756616 BG757391 BI113700 BF203602 BF973612 BU787935 BE280571

BE256333 BQ787730 BG335357 BG479156 BG332313 BG336378 BG758287 BF310442

BF683546 BQ061827 BG576369 BX395294 BI261487 CB110289 BF313038 BU590193

BE390350 BQ278853 AW951722 CB150774 BQ941858 BE889030 BG828099 BF975375

AA308105 CB111141 BE385074 AW328478 CR620738 AA935056 BE271465 BM842140

BU856185 BQ051778 BI195087 BI918669 BG489778 BF317022 CD106732 BG767496

BF312531 BG478034 BE910695 AI052305 BM558018 AA147118 BG684927 BM908251

BE408015 F28180 AJ710254 BQ064308 BM044975 BQ070057 AW850726 BG490510

BU542541 BQ061812 AA315822 BE384899 BX328493 BG768265 BM048336 BG491525

AI735335 BG385499 BQ641372 BG478580 AA379593 CB123398 BM810134 N26143

BG686729 BF314908 BU167142 BU164338 AW629704 BG528673 BQ933099 BE295682

BG685897 BF726403 BM050186 BQ278128 BG576789 BG758526 BG759051 BE885653

BF685487 BU856854 BE385574 AW410350 BF684469 BQ066144 BF974411 BQ066655

BQ955405 BG471641 BQ653006 BG330469 BQ648699 AW518593 F29266 AA378839

AA938215 BX328492 BG394294 BF975476 BE619202 BU859576 BF662980 BG755975

BU500355 AA564266 BQ061221 N85181 F18860 BG394329 BF311309 BM045030

BI260830 BM010584 BU955943 CB265867 BF311581 BG686331 BI198045 BM911714

BU197993 BG481631 BE280126 BG034588 AA872871 BG325136 BF973163 BQ935862

F34832 BQ642600 AA303192 BM045065 BE254080 BE515136 AA316529 BG827567

BM855846 BG469762 BG827349 BI199629 BV171058 AW571427 BE731234 BG576243

BG751266 CB117464 BQ353939 BM560880 BG756428 BU159333 BM798839 BF975295

BG249375 BE389869 BI160171 BE857350 BG341531 BE779586 BM834132 BU927696

BU854727 BG774471 BU932047 BF976160 BE785093 BF685603 BI828835 BG832076

BE260750 BQ957143 AJ713862 BE619166 CD674645 BM911519 BF663231 AA700381

BG341851 BF664411 AW377002 AA420489 BG757511 BQ054604 AI800130 BI199539

BU500770 BI754709 BG477042 AW732601 BU552551 BI861948 BM557642 AI494361

BG491673 BG757580 BE251271 BI260776 BQ888283 BU934973 BU541758 BG332743

BE301241 BM811448 D56202 BG770539 BG760897 AI954241 BM009993 BM760299

BF309117 BU539861 AV712179 BE733304 BM768310 BG490474 BG028477 CB150785

BE620770 BM840989 AA977828 BI824969 BQ064784 BM761580 BM989657 BQ061813

BQ065349 BG333531 AA469017 BI857080 BE408806 AL515642 BQ649437 F24448

AA902307 BM915947 BM841166 BM912067 BV189276 BF304486 BU539812 CD102208

AA513803 BF973597 BE613717 BM782111 BM795097 BF664277 BF663500 AA083785

AA973242 BM562048 BG323733 BU789892 BI200028 BQ876307 BQ276445 BG489370

CB107225 BU166856 BE386740 BQ054588 BM841280 BE731466 BG898237 BM810848

BQ931396 BE733801 BQ882052 BF315217 BF965656 BF026127 BE732477 BE894388

BE902747 BQ654228 BG397907 BQ643869 BM827592 BM272822 AJ706170 BG332897

BI084139 BE900913 BM811005 BM460158 BG032122 CD638505 BE385032 BF174018

BG338334 BF183918 BQ877753 BQ065022 CB123473 BF976518 BQ924183 AI564812

BG341919 BE389627 BF026467 BG341427 BU955823 BM845566 BM912252 BG686270

AA530990 AA345225 BU855813 BQ642197 BM760438 BQ931081 BE385389 BE734031

BQ919178 BM755799 BF975072 BF684974 BQ214709 BM423585 AA300565 BV171057

BQ945236 BI759866 BG758912 BM550811 CB109527 BG755211 BU165091 BQ052591

BG771886 BU541295 BQ063880 BQ070044 BQ680107 BM008988 AA503967 BU146711

BI114817 CA419946 BG489593 F20673 BQ052717 BF662968 D52796 BQ934353

F25186 AA716733 BQ058806 BG332534 BM918393 AA164544 AA228991 BQ962174

CA455425 BQ932993 BG281312 BQ670227 BE618499 BG477027 BM807851 BM915014

AW102862 AV712364 BU187499 BM826646 BF684987 BI710924 BF204897 BG684851

BU181738 CB106429 AI797962 AL701793 BQ051801 BG475409 AI168059 BF664256

BE784660 BQ678121 BF129003 BQ878822 BU856217 BU507554 BE900210 AI815861

BP372377 BQ787908 CB146185 BM850898 BE018313 BE208558 BM512554 BF182748

BU149269 BU539233 BM689852 AW270019 BE389813 BQ684502 BG759559 CB108530

AA862802 BG330375 BQ063577 BG425345 BG116450 AA369165 BF684430 BE278639

BG330463 BE258034 BG339117 BG480301 BM838430 BM047757 BM047151 AJ712873

AI192711 BU542885 BQ675776 BF204892 N26506 BG942546 BF313212 BQ278119

BG760067 BE390442 BE263632 BU553646 BF127467 AA328861 BE727817 BM915412

CB135836 CF127224 BE392694 BM911847 AA339178 BU508143 CB127171 BE395010

BQ071720 BI917566 BG754805 CB134964 BI195125 AA652822 BQ062419 BI092797

CB150414 BE281364 BG753555 BE298321 BG488731 BX384111 BF476486 AA351989

BQ055473 BG397779 BF206494 BM563105 BG490645 BM841861 BF182817 CB109463

BQ064652 CA336167 BQ917781 BG398574 BU074695 BP870994 BE252148 BF976275

BQ066314 BQ054438 AI630107 BG398061 BF976712 BQ062313 AJ712478 AI745333

BG436994 BE879893 BE908545 BM010478 BQ056372 BF182851 BG828934 BM981703

BU188698 BG490464 BM006259 BG473018 BM853901 AW572625 F25393 BE253118

BF663342 BF975325 BU844997 BQ072092 BM914888 BE904114 BG330628 BE261978

BG759320 BQ070263 BF975800 AA311747 BM914080 BE280508 BG437644 AW518438

BF688755 CB107437 AA558009 BF176151 BQ957646 BM476379 BQ676928 BF726321

BG655485 BU538165 BE728873 BX391082 BU538330 BU148517 AW337403 BG397900

BG329839 BF183175 F16778 AA659051 BQ652132 BG747044 BM048576 BG751948

BE902853 AJ715190 BQ073482 AI654263 BG025621 BG386354 H87124 BU538440

BM855533 BU558150 BG488961 BI086631 BI261665 BG474678 AA730537 BG338021

BU957568 BF221750 AL047809 BG438161 BM454338 BM811085 BG489040 BC022370

BF203479 BE879788 BG576237 BQ955149 AA329349 BG709587 BF686444 BM838345

BP870831 BQ278865 BQ057917 BU859291 BI857092 BM915807 AJ572023 AA658512

BG489235 AL539222 AA888659 BP382214 BM912340 BQ020856 BM810139 AA182931

D51425 BU146912 AA225295 BG337582 BM475283 BF316955 BG273022 AV699056

AA352513 BU957677 BM019731 BM010413 AA700677 BU939829 BU848995 BP350240

BF221738 BI085254 BE274764 AI986309 BU789824 BG477087 BU859411 BM916064

BI862080 AA329268 AJ713444 CB109971 CD173959 BU860326 BM910050 AA380284

AJ714574 AA639038 AI066627 AA876041 BG928726 BE258531 BE275069 BU500400

BM008905 BG032053 BM008998 BU957904 BM916136 BM010451 AI302159 BI907198

AA729115 BQ063900 BM048804 BF740185 BU152694 BU943448 BU595939 BQ422202

N83143 AJ713794 AA649836 F18234 AA886010 AA370438 BM912158 BF683653

AI818051 BG338860 BQ684183 BG178172 BG752925 BM019752 AW410317 AA528117

BM785079 AA503331 BQ643120 F20587 BU162614 AA326802 CD639959 BF698598

AA528752 BG684955 AA026301 AA308162 AA362338 BU537630 BU500570 BM850912

BM558592 BQ052463 AW328499 AA299022 BQ063195 BP872764 AW469877 AA687666

BF975477 AW374073 BM990277 BU535135 AA558175 BM008893 D54117 BQ054871

F32498 AA630762 AW081151 BE304660 BG476018 BQ684482 BM911078 BQ935504

BQ062254 AA482707 BE539579 AA552198 AI288850 BQ053411 BQ882717 BG682928

CD177477 BM558319 AJ715124 AA886126 AA528540 AA760934 BM562393 AA384261

AA736556 BQ056522 BE615230 BG179384 BQ650228 AA375459 BM911446 AA661463

BE548172 AA877444 BG223153 BG751331 BG496221 BG232055 BQ685951 BF238277

BQ887582 CB117910 AA311395 BF128641 BM012880 AI358755 F27746 BG685995

BQ061392 AI399651 BV184235 AA384255 F33430 BM809660 BM810187 BQ643389

BE274713 AI970790 BF307819 BF569709 BM048774 BM008960 BQ052357 AA884463

H51443 AV714311 AW328322 AI669538 BF311662 BE732579 BQ892590 F32381

BU565746 AI918262 T47173 AA977878 AA483124 AJ573601 BU856870 BF664187

CB127569 AI214843 AA531392 AA326995 CB116842 BM915091 BX353158 CA336391

AA513490 BU858140 AA746213 BF182985 BF685435 AA579124 BU860119 AA082129

CN484827 BG257674 BU956124 AJ713706 F30503 AA484315 D50982 BG754914

BM841411 BM423714 BM047813 BG471252 BF939432 BQ278904 AA359872 AA329035

BM562557 BM471640 AA324980 CD249015 AA577020 CD387902 AA558870 BG398560

BP871496 BQ059045 AW973971 BI856009 AA664539 BM044234 N35559 BI261797

AA352384 BQ063164 BF307114 BG481702 BG755749 AW515976 BQ219934 CD694856

BU860270 BQ918183 BF196829 BQ056560 BQ062552 CB050422 T58502 AI718220

N47930 BX349452 AA507533 BU860497 BQ651391 AV752425 BM969789 F27573

BI196175 BQ678537 BF797938 AA983321 AI658840 D54151 BG757998 BP429937

BI909360 BE298996 BQ943733 BQ709296 CB128425 BG755924 AW817684 AA632474

F32092 AA375892 AA576246 BQ919190 AI707689 BI115547 BM046539 BQ062773

BM746774 BM916300 BQ052827 BG327900 AA627394 BM912795 CB108548 D55302

AI969969 BI463080 BU532918 BE253649 AA569463 BI835083 AI042195 BU149529

BE732176 BU603264 AA632540 BG831891 BQ064735 AA642697 BE616201 AJ712745

AA181582 BM556582 BQ648120 BU535450 AI744513 BM838458 CD671885 M13932

BE250239 AI201141 BG481962 BP363274 AI420600 BF313554 BQ939626 BG478275

BF314969 F30989 BQ962544 N88561 BU179501 AI224544 BG755162 BQ062170

BE771999 BE251078 AA380678 F20618 AA630908 BG292425 BQ053176 BF207188

BM807778 BQ421056 AI865610 AA862657 CD385291 BM760055 BE395603 AA625713

AA737806 BE251692 AJ709633 BF685817 AW675402 BU857375 BQ948809 BF976369

BF690476 AW023891 BU859970 BM809956 BF973513 AJ712566 AA483390 AI399878

BQ061165 CF124020 BQ944323 BQ669427 AJ715069 BF662987 BM542996 CF122642

BI833348 BU196689 BE277994 BF594916 CD247758 AA714979 BG490733 CD385764

AJ714502 BM915031 BG395609 CF124297 BE408860 AW152518 BU588352 BQ053330

BQ672550 AJ714481 BE531302 BX395300 BM048211 AA526815 BQ060112 BQ876172

AA773244 CD172958 CD387900 CD385671 BP379747 BF331539 AA659583 BG771982

AA354781 AA506679 CA337444 CF122685 CD388169 AA095622 BG684198 BM558915

BU858156 BP342214 BM923178 CD386408 AA548898 AA661872 CD389430 BQ683717

BQ062033 BQ932871 BF664210 F20224 AJ713455 CA438056 BU956116 BM913085

BE902183 BE409495 AA687529 AA632431 AV693553 BE378330 AJ712441 AA862563

AA578103 CD390029 AA641609 F22146 N88907 AA570200 BU174246 CD385688

AA988333 BM909940 CB995291 AA335866 BU564633 BQ059941 CD174197 CD173941

AA505422 BQ055147 CD172591 AI359232 CD387347 BM559571 AA557748 BM810109

AJ714584 CD389752 AA229271 AA082519 BP373928 CD175446 BQ957041 BE384587

F27702 BM010022 AA506663 W79719 CB049437 CD172573 BE512808 CB127308

CD243254 BF684813 W23643 BQ372959 CD177109 BG758987 BQ212182 BM729943

BP429104 BF437646 BG685181 BQ709660 BM831698 CD176294 BE902482 T23894

CD387432 BI768074 AJ715280 CF122501 BM811365 CD389906 AA742742 CD177052

BU566668 AJ713990 BM470156 CD385944 AI926964 N88764 AA094742 CD385469

BM916767 BP379750 BM810972 BE731535 BG765195 BU527716 AA558159 AA578190

CK125969 AA211349 CD385666 CF123543 BQ927337 BG775112 CD177038 BG825878

CD175976 CF124512 CD174176 BG758875 AA339585 BM916200 AA569703 AV695787

BX347675 T25947 BM009041 BE261548 CD389155 CD385096 AW410182 CD690465

AW873375 CF995402 AJ706526 BU539089 CD388631 AA864316 CD388056 CD385159

AJ713067 AV752729 CD174599 CD387584 AJ715251 CF124874 AJ712495 BU858023

AJ712569 AA362339 BU603794 AJ714559 BG756647 BM994778 CD556216 BQ709343

BG340840 AI749943 BQ882418 BP377773 AA578164 CD247722 BU595622 AA557934

CD177086 BE261338 BQ052755 BQ957822 BM020682 BG329296 BP364251 CD386935

CF124026 D51055 BQ050042 AA564551 BG331511 BG030486 BQ062080 BQ054641

BU537764 AA632546 CD387642 BI193459 CD387337 AA230301 AA635805 BM912903

BM976537 BM850495 BE270297 CF780515 CD678183 CF124251 BI225794 BI193373

AA600923 AA657473 CD389376 BQ050002 BQ883400 CD048936 AA298682 AV687519

BP364749 CD174606 BE258396 BQ058599 AA081155 BU160311 AW328485 CD175597

CD247366 CB127258 AA355603 BE257862 CD385551 AA573728 AA384489 BG339055

BG489026 CD385059 BG389446 BQ053909 CD385305 BM807635 BU955091 CD513924

CD385005 CF124653 BQ672403 CD385931 BU557087 AW327544 BF569257 AA483772

BU535667 BG655425 BI762337 AA559181 AA095084 N83273 AI367438 AW772832

BI493341 T58465 BE408402 AI699063 AA657877 CF124363 BU598615 AA578076

BG759611 BM927537 BQ059895 CD173791 BG397658 AA593096 AW082047 BM556351

N87810 BE407608 CD176346 BG532129 AA557800 BI334243 AU126707 AA654729

CF123460 AA505487 BG470752 BG113249 AA362240 CD173471 CD250190 CD387569

BM043424 AA876558 F34208 BQ053618 BU196544 BE304456 BQ950885 AI263991

CN478599 BE252861 CB962554 CD246677 BU565681 CD175374 AA614285 BM800353

CD389739 BM551145 AJ713102 BF796787 BP870451 CD387225 BM808588 CF124129

AA372373 BM807514 CB149795 AA654829 BI752757 CD177173 BM554357 AJ714617

CB114025 BQ686794 BG397919 CD386906 BG152976 BI334307 BU589475 AV742844

CD247131 CD174001 CD174853 AA319418 BG702201 BG470557 BE559621 BF206334

T03919 CD247077 F22457 CD389335 CD385098 D57028 AV756790 BU540242

CD386222 CD386113 BU596245 BU175446 BE298317 CD555936 AA507515 AA552791

CD385141 CD387851 BE901261 CD386841 BU854721 CD175338 CD386902 BE267729

AA653883 CD177347 AA617717 CD386328 AA469328 CD387138 CD386267 CD175637

CD176169 CF995300 CD177436 BP379754 BE280064 CD246901 CD177248 BM469152

BE260668 CD248230 CD385402 CD177596 AA320906 CD386922 CD249555 AI266116

AA092967 BG480189 BI599193 CD175432 BM834066 CD387675 BE384629 AA135228

AI351130 BU500913 CD175207 BE838492 BM557478 CD386334 BI910335 BE385271

BQ896074 CD556369 CD175380 CD385166 CD385274 CD246661 BM824316 CD177498

CD175331 CD177268 BQ057782 BF203644 AA146887 CD176060 CD247195 CD556077

CD246863 BF381574 AA155895 CD388505 CD389646 CD387086 BQ222096 CD173243

BF026478 AA661561 AI682182 BQ650693 BE735674 BE877510 BE409225 BM801614

AA558745 CD385680 CD390267 BQ049993 CD384949 AA533415 BF699208 BQ057604

F33904 AJ710241 AI253523 AV739971 CD174646 BE515043 AA592972 AA935024

AI306144 BQ028635 CD388470 BE771995 BE395977 BF684723 CD250341 D56973

CD385623 BG900787 AI869198 CD174594 AI907724 CD248329 CD384845 AA316346

AJ715169 CD248623 BI818877 CD174677 AA306390 CD172642 BE838488 CD387331

CD389177 BP872245 CD388699 BE771972 BG106827 CD173544 CD174265 AA297897

CD247294 CD174119 CD174583 AA187090 AA873657 BG034564 CD173618 BE094055

AA879172 BG616267 BG755153 AA630907 BI481321 CF123501 CD387671 AA339893

BQ372957 AA091567 CD174040 CD176365 AA167246 CD387891 CD389306 BM790466

CD387188 BG490890 BG684974 BQ957824 BI254913 CF780521 CD173119 AW970048

BG519798 CD175268 CF124078 CD173038 CD556029 BU565550 BG491765 AI762814

BF173357 AV759671 CD389218 CD172854 N84542 CD386193 CD386867 AA385226

AA186859 AA559338 D20891 CD386606 BE789283 BG397502 AA031755 CD249867

CD385345 BU589447 CD386892 CD174289 BF245836 CD176170 F23549 BU596477

BM557487 AA155866 BG177262 BI600916 CD249636 CD386123 BE731993 BE274058

CD386124 AA559228 CD176503 CD390171 CD388365 BE301354 BM554039 CD386844

CD174936 CD174068 CD388968 BE531167 BQ918246 CD176481 CD105463 AA744281

CD388129 CA337527 CD249934 BE734969 BM562505 BI868428 CD173981 BE407613

BG340334 W24027 AA492433 BI906390 BF792115 BU860732 BE881077 BQ372958

AA630994 BG488849 BE408339 BI193703 BE771973 BG291004 AW572649 T28929

AI580754 AW089727 CD177323 AA318965 BE731975 AU099768 AV706474 BU596809

BU955139 BU854538 AA778088 CB997602 BX401763 CD388227 CD384972 BM465855

BG769588 AA962607 BF819101 BV202674 CB107273 BF683287 BU935079 BF127417

BG332910 W24496 BQ439011 N85467 CD389188 BG190344 BF663475 BE407588

D55082 C14003 D19803 BE298213 AA579446 BG686040 W39565 BU598352

AA578457 BF684907 BF025699 BF240209 BU599539 BG531612 BE091153 BG396710

BF690059 CK128652 BQ421793 BE818745 AA569712 CD248086 BU603397 BI093590

BE513471 F28377 AV760421 BU537672 BI457711 BG755790 AW103787 BM912236

AA552867 BQ440614 AA320859 BI521261 CA338086 BF244424 T55816 D52611

CD175004 AA491897 BQ421744 BE545831 AA938479 AJ705161 BP870813 BG502735

H87136 CD175371 BG611061 CD388109 BE731594 CD247000 AA558292 AA834715

BF222006 BF476541 AA903378 AW392185 CD386223 AA301805 AW275163 BM825263

D17278 BU566016 AA557832 BG475391 AA090578 BE905390 AI284582 AA947382

CD177629 BG424131 BM463542 AA569454 BM793748 AA603253 AA327939 N85429

AW583000 BG878452 AA559946 BE301376 BE729651 BG281659 BE271834 BG831406

CD387087 BG330821 AV764466 AI582473 BI257148 AV715580 BF241440 BG107475

BU599263 BU960442 BG339822 BG339748 CD177366 BE386897 BG760073 BG765090

BG387098 BG024742 BF104109 BF664287 BG473593 BE694784 AA747156 BE880653

BM465151 AW674251 BG394696 BG779740 BG682179 CD177654 BG753659 AA635747

BI856924 AA096069 AA094178 BG766552 BG335384 BQ312017 AV711696 BG341517

BG491548 BE275175 BG437587 CD173273 BI089254 BG831674 BE278723 AI220666

AV698400 BF791682 BE390840 CD387196 CD246308 BI856536 BM797671 BE818739

BF976579 BI856118 BE731089 BQ278513 BF103905 AA658859 BM912937 BG033132

BF182827 BG281793 BG341051 BF664186 BG397603 AV705648 BF209648 BE615422

BI822826 BG031308 AI440310 BG169951 CD388346 BG332480 BI763497 BI087505

BU941298 BF311336 BI754918 BE789883 BF980991 CF124909 BG114990 BG758907

BE265734 BF797828 BE746686 AV736787 BM914962 BE744562 BE409226 BE379113

BG686171 BF308295 BX399590 BF699947 H94369 BE271774 BG387102 BG469819

BG474699 AA304646 BM841668 BG478080 BG533661 BG472703 BF975552 BG501224

BF976060 BG613492 CD389986 BE313309 CD388035 BI762604 BF663558 BE276650

BF312601 BE383933 CA748848 AA662567 BG281237 BE280680 BE731291 BG331902

BG398181 AA559907 BG774725 BG119329 BI759836 BI199658 BU959868 BG762446

BG481014 BE732348 BE271477 BI029521 BU564237 CD174356 AV760907 BI198479

BG290072 BG282705 BF128734 BQ226741 BI909681 BG329015 F34812 BE903025

AA524770 BE389646 AV735630 BG878451 BM015885 BE621021 BI761824 BF976105

BU933286 BG180316 AA922446 BF681353 CD389237 AA627190 BI836057 BI754807

BU172990 BU954493 CB984858 BG340745 N88615 BG758126 AV697308 BE296964

BG110660 AV707055 BI457498 CD387035 AA858143 BE736166 BG329907 BG337851

BE250796 BM014785 BG328210 BE257170 CD385271 AA828863 BQ678679 CD246968

BG498827 BQ687463 BF975610 BF686275 N64055 BE694003 BF211491 BG499466

BM911212 BQ056991 BG164942 BE818716 BE301323 BE905726 BF329955 BE392604

BE280089 BF034141 CD248091 BF238036 BF663862 BG281882 BG496920 AV751480

CD388941 BG684514 BQ222422 BG285654 CD390135 AV756654 BG755061 BE771954

AV759312 BE772932 CD175479 CD248661 BF310146 N85502 AA091203 BE900219

AW949699 BG421719 BE260452 AA557884 AW157323 CD247851 AI826819 BF239298

BU537291 AW157324 CD174561 AA595310 AW409743 BF372970 AA527955 CD048017

BQ065417 AA186435 F37881 BF375458 AA640276 AJ714750 BU587219 CD389519

CD389302 N87566 AA773652 BE268358 BG397073 BG473809 AJ712493 AA186344

BG751206 BF129088 AI434756 AV711300 BE258128 BE293899 BU158533 CD390150

BE730742 BG490185 BE902086 BE393827 BE278007 AV702378 BG331330 BU557830

BQ228431 BF127774 BU553221 BG028962 CD050080 BG331875 BE279967 BE737266

BE732576 BM006596 BG330994 CD247154 BI194969 BE732087 BG281544 BE744269

BG329344 BE818719 BF131674 AV738610 BE298132 BE277128 BE567392 BE281517

BF244466 CD386990 BI769479 BG479543 BF237841 BF127884 BE313155 CD556024

AV758182 BE737775 BE252660 D57108 AA736539

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RPS17 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCCGCGTTC

About this image

RPS17 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Cells

Primary Follicle

Positive expression

Microarrays (high-throughput)

Female Gametocytes, Germ Cells

Expression:

Positive

Negative

cell-identifying gene

Selective marker

Experimental details:

Curated

High-throughput

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Protocol derived cells

Endoderm-like cells (Generation of hepato...)

Positive expression

Microarrays (high-throughput)

See RPS17 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RPS17

SABiosciences Custom PCR Arrays for RPS17

Primer Products:		Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RPS17
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS17
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS17

In Situ
Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS17

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for RPS17 gene from 9/37 species (see all 37) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	--	Uncharacterized protein	85(a)	1 → many	10(707000-709787)
lizard (Anolis carolinensis)	Reptilia	--	--	99(a)	1 → many	GL343479.1(636199-639072)
African clawed frog (Xenopus laevis)	Amphibia	Xl.8337²	Xenopus laevis transcribed sequence with strong similarity more	79.49(n)		CB943667.1
zebrafish (Danio rerio)	Actinopterygii	BQ418878.1²	--	83(n)		BQ418878.1
fruit fly (Drosophila melanogaster)	Insecta	RpS17^{1 , 3}	protein biosynthesis structural constituent of more³ Ribosomal protein S17¹	79(a)³ 72.95(n)¹ 81.15(a)¹		3 67B4³ 39088¹ NM_079278.2¹ NP_524002.1¹
worm (Caenorhabditis elegans)	Secernentea	rps-17³	40S ribosomal protein S17	71(a)		I(6228214-6228815) --
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	RPS17B(YDR447C)⁴ RPS17A¹	Ribosomal protein 51 (rp51) of the small (40s) subunit; more⁴ Rps17ap¹	63.91(n)¹ 69.72(a)¹		4(1355553-1354829)⁴ 854984¹ NP_013688.1¹ 852058⁴ NP_010735.1⁴
thale cress (Arabidopsis thaliana)	eudicotyledons	AT2G05220¹	40S ribosomal protein S17-2	58.2(n) 62.7(a)		815070 NM_126548.4 NP_565320.1
rice (Oryza sativa)	Liliopsida	Os.46371²	Transcribed sequence with weak similarity to protein more	71.13(n)		CB966919.1

ENSEMBL Gene Tree for RPS17 (if available)
TreeFam Gene Tree for RPS17 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RPS17 gene

RPS17L¹ ²

2 SIMAP similar genes for RPS17 using alignment to 2 protein entries: RS17_HUMAN (see all proteins):

RPS17L LOC392101

RPS17 for paralogs About GeneDecksing

5/26 Pseudogenes.org Pseudogenes for RPS17 (see all 26)
PGOHUM00000242480 PGOHUM00000247171 PGOHUM00000237351 PGOHUM00000244323 PGOHUM00000262142

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 15 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs116840811^1,2	C	pathogenic	82824835(-)	`CAACAG/TGGTAG`	2	R M	mis¹		0	--	--	--	--
rs148810247^1,2	--	--	82822408(+)	`GCAGGC/GAGATT`	1	--	int¹		0	--	--	--	--
rs147055789^1,2	--	--	82823632(+)	`CCCCCA/CACTCG`	1	--	int¹		0	--	--	--	--
rs141293730^1,2	--	--	82826010(+)	`TTTTTG/TTTTTT`	1	--	us2k¹		0	--	--	--	--
rs151257277^1,2	--	--	82823423(+)	`GAACAA/GTGAGA`	1	--	int¹		0	--	--	--	--
rs146994952^1,2	--	--	82826601(+)	`CCCAGG/TCTGGC`	1	--	us2k¹		0	--	--	--	--
rs140453700^1,2	--	--	82823466(+)	`ATGTGC/GATATA`	1	--	int¹		0	--	--	--	--
rs116840812^1,2	--	pathogenic	82823348(-)	`AGTAA-/GAGGTAT`	2	R	fra¹		0	--	--	--	--
rs147695112^1,2	--	--	82825597(+)	`TCAGGC/TACCTT`	1	--	us2k¹		0	--	--	--	--
rs142262304^1,2	--	--	82823390(+)	`GTGACA/GTAACT`	2	Y	syn¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for RPS17 (82821158 - 82824972 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for RPS17
8 CNVs: 0190 30716 3972 72314 72323 2197 7074 0788
Human Gene Mutation Database (HGMD): RPS17

Locus Specific Mutation Databases (LSDB): RPS17

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPS17

DNA2.0 Custom Variant and Variant Library Synthesis for RPS17

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RPS17 for disorders           About GeneDecksing

OMIM gene information: 180472
OMIM disorders: 612527
UniProtKB/Swiss-Prot: RS17_HUMAN, P08708

Defects in RPS17 are the cause of Diamond-Blackfan anemia type 4 (DBA4) [MIM:612527]. DBA4 is a form of

Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy.

Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an

increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital

anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital

anomalies

13 diseases for RPS17: About MalaCards

diamond-blackfan anemia macrocytic anemia short stature cleft palate

reactive arthritis aplastic anemia macular degeneration anemia

arthritis ataxia malaria leukemia

2 diseases from the University of Copenhagen DISEASES database for RPS17:

Diamond-Blackfan anemia Pure red-cell aplasia

GeneTests: RPS17

Diamond-Blackfan Anemia

Human Genome Epidemiology (HuGE) Navigator: RPS17 (2 documents)

Export disorders for RPS17 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RPS17 gene, integrated from 9 sources (see all 54):
(articles sorted by number of sources associating them with RPS17)

Utopia: connect your pdf to the dynamic
world of online information

[Mapping the genes for ribosomal proteins S14 and S17 on human chromosomes using cDNA from a panel of hybrid cells] (PubMed id 7661859)^{1, 3, 9} Filipenko M.L....Mertvetsov N.P. (1995)
Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients. (PubMed id 19061985)^{1, 2} Gazda H.T....Beggs A.H. (2008)
Ribosomal protein S17 gene (RPS17) is mutated in Diamond-Blackfan anemia. (PubMed id 17647292)^{1, 2} Cmejla R....Pospisilova D. (2007)
Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)^{1, 2} Zody M.C....Nusbaum C. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)^{1, 2} Vladimirov S.N.... Otto A. (1996)
The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome. (PubMed id 1577483)^{1, 3} Feo S....Fried M. (1992)
The transcriptionally active human ribosomal protein S17 gene. (PubMed id 3240863)^{1, 2} Chen I.-T. and Roufa D.J. (1988)
Homologous ribosomal proteins in bacteria, yeast, and humans. (PubMed id 3529092)^{1, 2} Chen I.-T.... Roufa D.J. (1986)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

			AND	OR
	Aliases
	Disorders
	Free Text

	Query String		PubMed OMIM NCBI Bookshelf
		(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 6218	HGNC: 10397	AceView: RPS17	Ensembl:ENSG00000184779	euGenes: HUgn6218
ECgene: RPS17	Kegg: 6218	H-InvDB: RPS17

(According to HUGE)
About This Section

--

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for RPS17	Pharmacogenomics, SNPs, Pathways
Diamond-Blackfan Anemia mutation database	http://www.dbagenes.unito.it/home.php?select_db=RPS17

Intellectual Property for RPS17 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for RPS17 gene:
Search GeneIP for patents involving RPS17

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for RPS17
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS17		Browse OriGene genome-wide validated SYBR primer pairs
	Browse OriGene Protein Over-expression Lysates		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for RPS17		OriGene 3'-UTR Clone for RPS17
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPS17		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPS17
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for RPS17		OriGene Custom Protein Services for RPS17
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RPS17
	Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPS17
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS17
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS17
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS17
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS17

	GenScript Custom Purified and Recombinant Proteins Services for RPS17		GenScript cDNA clones with any tag delivered in your preferred vector for RPS17
	GenScript Custom Assay Services for RPS17		GenScript Custom Superior Antibodies Services for RPS17
	GenScript Custom overexpressing Cell Line Services for RPS17		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in RPS17 promoter
	Search Chromatin IP Primers for RPS17
	RT² qPCR Primer Assay in human, mouse, rat RPS17
	Search GNC Networks for RPS17
	SABiosciences Custom PCR Arrays for RPS17

Search Tocris compounds for RPS17

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	RPS17 antibodies
	RPS17 proteins

	Search for Antibodies for RPS17 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for RPS17
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

RPS17 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for RPS17

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS17

	Browse SwitchGear 3'UTR luciferase reporter plasmids for RPS17
	SwitchGear Promoter luciferase reporter plasmids for RPS17

Search ThermoFisher Antibodies for RPS17

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS17

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.

Hot genes Disease genes RPS17 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4