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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPS16 Gene

protein-coding   GIFtS: 60
GCID: GC19M039923

ribosomal protein S16
 Explore 8 diseases affiliated with
RPS16 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RPS16    

Aliases
for RPS16 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Ribosomal Protein S161 2
S161 2
40S Ribosomal Protein S162

External Ids:    HGNC: 103961   Entrez Gene: 62172   Ensembl: ENSG000001051937   OMIM: 6036755   UniProtKB: P622493   

Export aliases for RPS16 gene to outside databases

Previous GC identifers: GC19M040561 GC19M040315 GC19M044596 GC19M044615 GC19M036370


Summaries
for RPS16 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RPS16:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene
encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S9P family of ribosomal
proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple
processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

Gene Wiki entry for RPS16


Genomic Views
for RPS16 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPS16 gene promoter:
         ISGF-3   p53   GATA-2   YY1   GATA-1   Ik-2   HSF2   ZIC2/Zic2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RPS16 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPS16

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.1   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.1

RPS16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS16 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M039923:  view genomic region     (about GC identifiers)

Start:
 39,923,847 bp from pter      End:
 39,926,618 bp from pter
Size:
 2,772 bases      Orientation:
 minus strand

Proteins
for RPS16 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RS16_HUMAN, P62249 (See protein sequence)
Recommended Name: 40S ribosomal protein S16  
Size: 146 amino acids; 16445 Da
Secondary accessions: B2RDD5 P17008

Explore the universe of human proteins at neXtProt for RPS16: NX_P62249

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P62249

    • RPS16 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001011.1  
    ENSEMBL proteins: 
     ENSP00000251453   ENSP00000367806  
    Reactome Protein details: P62249
    Human Recombinant Protein Products: 
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    Novus Biologicals RPS16 Proteins
    Novus Biologicals RPS16 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RPS16

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0015935small ribosomal subunit IDA15883184
    GO:0022627cytosolic small ribosomal subunit NAS2016298


    RPS16 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for RPS16

    Protein Domains /
    Families
    for RPS16 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RPS16 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR020574 Ribosomal_S9_CS
     IPR020568 Ribosomal_S5_D2-typ_fold
     IPR000754 Ribosomal_S9
     IPR014721 Ribosomal_S5_D2-typ_fold_subgr

    Graphical View of Domain Structure for InterPro Entry P62249

    ProtoNet protein and cluster: P62249

    UniProtKB/Swiss-Prot: RS16_HUMAN, P62249
    Similarity: Belongs to the ribosomal protein S9P family


    Function
    for RPS16 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
         Genatlas biochemistry entry for RPS16:
    40S ribosomal protein S16,16kDa

    miRNA
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS16 (see all 4)
    OriGene shRNA RFP: RPS16
    OriGene siRNA: RPS16
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS16

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for RPS16

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPS16 (see all 2)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS16 

    Cell Line
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    Search LifeMap BioReagents cell lines for RPS16

    In Situ Assay
    Products:       
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS16

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IDA17881366
    GO:0003735structural constituent of ribosome IEA--


    RPS16 for ontologies           About GeneDecksing


    10 GenomeRNAi human phenotypes for RPS16:
     Decreased Hepatitis C virus re  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Decreased viability of wild-ty 
     Elongated cells  G2 arrest  Increased S DNA content  Increased gamma-H2AX phosphory 
     Nuclear 40S maturation defects  Nucleolar pre-40S maturation d 


    Pathways & Interactions
    for RPS16 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    		Viral Protein Synthesis1.00
    		Cytoplasmic Ribosomal Proteins0.86
    		Viral mRNA Translation1.00
    		CFTR translational fidelity (class I mutations)0.83
    		Influenza Viral RNA Transcription and Replication1.00
    		SMG6 Cleaves mRNA with Premature Termination Codon0.80
    		Synthesis of nascent polypeptide containing signal sequence1.00
    		L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Translation initiation complex formation
    		Translation initiation complex formation1.00
    		Ribosomal scanning and start codon recognition0.96
    		Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.98
    		Formation of the ternary complex, and subsequently, the 43S complex0.87
    3Metabolism of mRNA
    		Metabolism of mRNA1.00
    		Metabolism of RNA0.92
    4Disease
    		Disease1.00
    5Generic Transcription Pathway
    		Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS16
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS16 
        Cytoplasmic Ribosomal Proteins

    5/32        Reactome Pathways for RPS16 (see all 32)
        Formation of a pool of free 40S subunits
    Synthesis of PB1-F2
    SMG6 Cleaves mRNA with Premature Termination Codon
    Influenza Life Cycle
    Viral mRNA Translation


    1         Kegg Pathway  (Kegg details for RPS16):
        Ribosome


    RPS16 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPS16

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/517 Interacting proteins for RPS16 (P622492, 3 ENSP000002514534) via UniProtKB, MINT, STRING, and/or I2D (see all 517)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPS4XP627012, 3, ENSP000003627444MINT-6542674 MINT-8395092 I2D: score=2 STRING: ENSP00000362744
    RPL12P300502, 3, ENSP000003547394MINT-6542674 MINT-8395092 I2D: score=1 STRING: ENSP00000354739
    RPL26P612542, 3, ENSP000002938424MINT-6542674 I2D: score=5 STRING: ENSP00000293842
    RPL8P629172, 3, ENSP000002625844MINT-6542674 I2D: score=4 STRING: ENSP00000262584
    RPS2P158802, 3, ENSP000003418854MINT-6542674 I2D: score=4 STRING: ENSP00000341885
    About this table

    Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006364rRNA processing IMP18697920
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--


    RPS16 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RPS16 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPS16
    Search CenterWatch for drugs/clinical trials and news about RPS16 / RS16 

    Transcripts
    for RPS16 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RPS16 gene: 
    NM_001020.4  

    Unigene Cluster for RPS16:

    Ribosomal protein S16
    Hs.397609  [show with all ESTs]
    Unigene Representative Sequence: AK055869
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000251453(uc002olk.3 uc002oll.3) ENST00000339471(uc002olm.3)


    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPS16
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    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS16 (see all 4)
    OriGene shRNA RFP: RPS16
    OriGene siRNA: RPS16
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS16
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPS16 (see all 2)
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    GenScript: all cDNA clones in your preferred vector: RPS16 (NM_001020)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPS16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS16 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS16
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS16

    Additional cDNA sequence: 

    AK055869.1 AK315498.1 BC004324.2 BC007977.2 BC024970.1 BC071674.1 BC095429.1 M60854.1 

    24/67 DOTS entries (see all 67):

    DT.450891  DT.95150319  DT.91779566  DT.101956204  DT.101985755  DT.95297234  DT.92057789  DT.100739929 
    DT.97869259  DT.100739956  DT.100739936  DT.121504318  DT.100739962  DT.100867295  DT.100739967  DT.121504302 
    DT.91779557  DT.97869279  DT.100841456  DT.91787375  DT.100739965  DT.121504287  DT.121504322  DT.100739913 

    24/2309 AceView cDNA sequences (see all 2309):

    AA309818 AV648691 BF976680 BE383049 BM810885 BE394125 BE390753 BI856709 
    BQ056727 BQ303768 BQ682272 BG754991 BQ055575 AI459651 BM708622 BQ675607 
    AA324156 AI240337 CB108758 F33618 BU542798 AI626108 BP368635 AJ705425 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for RPS16 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c
    SP1:                                            -     -                 -                     
    SP2:                                            -     -                 -                     
    SP3:                                            -     -                 -                     
    SP4:                                      -     -     -                 -                     
    SP5:                                            -     -                                       


    ECgene alternative splicing isoforms for RPS16

    Expression
    for RPS16 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPS16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCGTCCAAGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    RPS16 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Endoderm-like cells (Generation of hepato...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RPS16 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPS16

    SOURCE GeneReport for Unigene cluster: Hs.397609
        SABiosciences Custom PCR Arrays for RPS16
    Primer
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    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS16

    Orthologs
    for RPS16 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS16 gene from 10/40 species (see all 40)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Rps161 , 5 ribosomal protein S161, 5 89.5(n)1
    100(a)1    		   7 (16.70 cM)5
    200551  NM_013647.21  NP_038675.21 
     283506525 
    chicken
    (Gallus gallus)    		 Aves RPS161 ribosomal protein S16 79.91(n)
    98.63(a)    		   417871  XM_416113.3  XP_416113.1 
    lizard
    (Anolis carolinensis)    		 Reptilia RPS166
    		 --
    		 85(a)
    		 1 ↔ 1
    		 5(37294046-37297765)
    African clawed frog
    (Xenopus laevis)    		 Amphibia CF271176.12   -- 80.97(n)    CF271176.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii rps161 ribosomal protein S16 82.65(n)
    96.58(a)    		   767765  NM_001076732.1  NP_001070200.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG40463
    RpS161    		 protein biosynthesis structural constituent
    of more3
    Ribosomal protein S161    		 88(a)3
    78.49(n)1
    88.65(a)1    		   58F13
    375801  NM_137841.31  NP_611685.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea rps-161 , 3 40S ribosomal protein S163
    Protein RPS-161    		 77(a)3
    71.43(n)1
    77.14(a)1    		   V(15002275-15003212)3
    1799981  NM_074289.41  NP_506690.11 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes RPS16B(YDL083C)4
    RPS16A1    		 Protein component of the small (40S) ribosomal subunit; more4
    Rps16ap1    		 57.97(n)1
    65.94(a)1    		   4(307789-306926)4
    8551741  NP_013863.21  8514764 
     NP_010200.14 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G183801 40S ribosomal protein S16-3 68.26(n)
    73.97(a)    		   831956  NM_121843.2  NP_197339.1 
    rice
    (Oryza sativa)    		 Liliopsida AK058697.12   -- 75.54(n)    AK058697.1 


    ENSEMBL Gene Tree for RPS16 (if available)
    TreeFam Gene Tree for RPS16 (if available) 

    Paralogs
    for RPS16 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPS16 gene

    RPS16 for paralogs           About GeneDecksing


    5/11 Pseudogenes.org Pseudogenes for RPS16 (see all 11)
    PGOHUM00000242766 PGOHUM00000242871 PGOHUM00000248698 PGOHUM00000237327 PGOHUM00000234356


    Genomic Variants
    for RPS16 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/119 NCBI SNPs in RPS16 are shown (see all 119)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1133811831,2
    		C,--36374811(+) CACCGC/GGCCCA 1 -- us2k12Minor allele frequency- G:0.04NA NS 150
    rs758973851,2
    		C,--36374883(+) CTCCAC/TTTAAG 1 -- us2k13Minor allele frequency- T:0.03NA NS 272
    rs576894421,2
    		--36375088(+) GGGATG/CCAGGG 1 -- us2k11Minor allele frequency- C:0.50CSA 2
    rs1906094621,2
    		--39923366(+) GTCTCC/TACAAA 1 -- ds50010--------
    rs789794301,2
    		C,--39923369(+) AAAAC-/AAAAAA 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs616395591,2
    		--39923402(+) GCTCTG/CGCCTG 1 -- ds50011Minor allele frequency- C:0.00CSA 1
    rs1133742431,2
    		C,--39923403(+) CTCTCG/ACCTGT 1 -- ds50011Minor allele frequency- A:0.50NA 2
    rs104152791,2
    		C,F,A,--39923432(+) ggcccG/Aggaag 1 -- ds50013Minor allele frequency- A:0.40NA WA CSA 5
    rs735479911,2
    		C,--39923496(+) CCATCG/CATACT 1 -- ds50011Minor allele frequency- C:0.50WA 2
    rs1809256021,2
    		--39923546(+) TAATCC/TAAGCT 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for RPS16 (39923847 - 39926618 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RPS16: --

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    Disorders / Diseases
    for RPS16 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RPS16 for disorders           About GeneDecksing

    OMIM gene information: 603675    OMIM disorders: --

    8 diseases for RPS16:    About MalaCards
    diamond-blackfan anemia    treacher collins syndrome    intrahepatic cholangiocarcinoma    cholangiocarcinoma
    anemia    prostate cancer    prostatitis    malaria

    1 disease from the University of Copenhagen DISEASES database for RPS16:
    Diamond-Blackfan anemia
    Human Genome Epidemiology (HuGE) Navigator: RPS16 (1 document)

    Export disorders for RPS16 gene to outside databases

    Publications
    for RPS16 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPS16 gene, integrated from 9 sources (see all 67):
    (articles sorted by number of sources associating them with RPS16)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and sequence analysis of the human ribosomal protein S16. (PubMed id 2016298)1, 2, 3, 9 Batra S.K.... Hollingsworth M.A. (1991)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (2002)
    5. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 3 Kenmochi N.... Page D.C. (1998)
    6. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (1996)
    7. [Human ribosomal protein S16 inhibites excision of th e first intron from its own] (PubMed id 20198863)1, 9 Ivanov A.V....Karpova G.G. (2010)
    8. Interactions of human ribosomal proteins S16 and S5 w ith an 18S rRNA fragment containing their binding sites. (PubMed id 19559069)1, 9 Malygin A.A....Karpova G.G. (2009)
    9. [Binding of human ribosomal protein S16 with the 18S rRNA fragment 1203-1236/1521-1698] (PubMed id 18318121)1, 9 Ian'shina D.D....Karpova G.G. (2007)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    External Searches for RPS16 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing RPS16 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6217 HGNC: 10396 AceView: RPS16 Ensembl:ENSG00000105193 euGenes: HUgn6217
    ECgene: RPS16 Kegg: 6217 H-InvDB: RPS16

    Other Databases showing RPS16 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RPS16 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPS16 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for RPS16 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RPS16 gene:
    Search GeneIP for patents involving RPS16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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