Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPS15A Gene

protein-coding   GIFtS: 61
GCID: GC16M018701

ribosomal protein S15a

 Explore 6 diseases affiliated with
RPS15A via our new
 Human Malady Compendium 
Biological research products
for RPS15A
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Ribosomal Protein S15a1 2
S15A1
40S Ribosomal Protein S15a2
S15a2
Up-Regulated By HBV X Protein2

External Ids:    HGNC: 103891   Entrez Gene: 62102   Ensembl: ENSG000001344197   OMIM: 6036745   UniProtKB: P622443   

Export aliases for RPS15A gene to outside databases

Previous GC identifers: GC16M018285 GC16M018721 GC16M018760 GC16M017336


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RPS15A:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene
encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8P family of ribosomal
proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple
processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

Gene Wiki entry for RPS15A


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPS15A gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   YY1   E2F-1   E2F   POU2F1   POU2F1a   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS15A promoter sequence
   Search SABiosciences Chromatin IP Primers for RPS15A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS15A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p   Ensembl cytogenetic band:  16p12.3   HGNC cytogenetic band: 16p12.3

RPS15A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS15A gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M018701:  view genomic region     (about GC identifiers)

Start:
18,792,617 bp from pter      End:
18,801,705 bp from pter
Size:
9,089 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RS15A_HUMAN, P62244 (See protein sequence)
Recommended Name: 40S ribosomal protein S15a  
Size: 130 amino acids; 14840 Da
Sequence caution: Sequence=CAA44568.1; Type=Frameshift; Positions=24, 37;
Secondary accessions: P39027 P39031 Q3MHD9 Q8C023 Q9BV24

Explore the universe of human proteins at neXtProt for RPS15A: NX_P62244

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P62244

  • RPS15A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001010.2  NP_001025180.1  

    ENSEMBL proteins: 
     ENSP00000318646   ENSP00000458528   ENSP00000457000   ENSP00000460069   ENSP00000459554  
     ENSP00000457001   ENSP00000457924   ENSP00000459373   ENSP00000458115   ENSP00000458052  
     ENSP00000460618  
    Reactome Protein details: P62244
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate (see all 2): RPS15A
    OriGene Custom Protein Services for RPS15A 
    GenScript Custom Purified and Recombinant Proteins Services for RPS15A
    Novus Biologicals RPS15A Proteins
    Novus Biologicals RPS15A Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RPS15A

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA15108328
    GO:0005739mitochondrion IEA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022627cytosolic small ribosomal subunit IDA15883184


    RPS15A for ontologies           About GeneDecksing



    RPS15A Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for RPS15A 
    GenScript Custom Superior Antibodies Services for RPS15A
    Novus Biologicals RPS15A Antibodies
    Search for Antibodies for RPS15A at Abcam  
    Uscn Antibodies for RPS15A
    ThermoFisher Antibody for RPS15A

    Assay Products for RPS15A: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RPS15A
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for RPS15A


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RPS15A for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR000630 Ribosomal_S8

    Graphical View of Domain Structure for InterPro Entry P62244

    ProtoNet protein and cluster: P62244

    1 Blocks protein family: IPB000630 Ribosomal protein S8

    UniProtKB/Swiss-Prot: RS15A_HUMAN, P62244
    Similarity: Belongs to the ribosomal protein S8P family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:
         Genatlas biochemistry entry for RPS15A:
    60S ribosomal protein S15A

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 2): RPS15A
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPS15A
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate RPS15A
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS15A (see all 6)
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS15A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RPS15A

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPS15A (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPS15A (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): RPS15A (NM_001030009)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPS15A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS15A 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RPS15A
    Search LifeMap BioReagents cell lines for RPS15A

    In Situ Assay
    Products:
       

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS15A

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding NAS9582194
    GO:0003735structural constituent of ribosome NAS9582194


    RPS15A for ontologies           About GeneDecksing


    5 GenomeRNAi human phenotypes for RPS15A:
     Decreased Hepatitis C virus re  Decreased cell number  Decreased viability  Decreased viability of wild-ty 
     Increased gamma-H2AX phosphory 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    Viral Protein Synthesis1.00
    Cytoplasmic Ribosomal Proteins0.86
    Viral mRNA Translation1.00
    CFTR translational fidelity (class I mutations)0.83
    Influenza Viral RNA Transcription and Replication1.00
    SMG6 Cleaves mRNA with Premature Termination Codon0.80
    Synthesis of nascent polypeptide containing signal sequence1.00
    L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Translation initiation complex formation
    Translation initiation complex formation1.00
    Ribosomal scanning and start codon recognition0.96
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.98
    Formation of the ternary complex, and subsequently, the 43S complex0.87
    3Metabolism of mRNA
    Metabolism of mRNA1.00
    Metabolism of RNA0.92
    4Disease
    Disease1.00
    5Generic Transcription Pathway
    Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS15A
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS15A 
        Cytoplasmic Ribosomal Proteins

    5/32        Reactome Pathways for RPS15A (see all 32)
        Formation of a pool of free 40S subunits
    Synthesis of PB1-F2
    SMG6 Cleaves mRNA with Premature Termination Codon
    Influenza Life Cycle
    Viral mRNA Translation


    1         Kegg Pathway  (Kegg details for RPS15A):
        Ribosome


    RPS15A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPS15A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/494 Interacting proteins for RPS15A (P622441, 2, 3 ENSP000003186464) via UniProtKB, MINT, STRING, and/or I2D (see all 494)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPS2P158802, 3, ENSP000003418854MINT-6542674 MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=4 STRING: ENSP00000341885
    RPS3P233962, 3, ENSP000002785724MINT-6542674 MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=4 STRING: ENSP00000278572
    RPL11P629132, 3, ENSP000003636764MINT-6542674 MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=1 STRING: ENSP00000363676
    RPL26P612542, 3MINT-6542674 MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=5 
    RPL35P427662, 3, ENSP000002594694MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=4 STRING: ENSP00000259469
    About this table

    Gene Ontology (GO): 5/16 biological process terms (GO ID links to tree view) (see all 16):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--


    RPS15A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPS15A
    Search CenterWatch for drugs/clinical trials and news about RPS15A / RS15A 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPS15A gene (2 alternative transcripts): 
    NM_001019.4  NM_001030009.1  

    Unigene Cluster for RPS15A:

    Ribosomal protein S15a
    Hs.370504  [show with all ESTs]
    Unigene Representative Sequence: BM907705
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322989(uc002dfh.1) ENST00000572008(uc002dfi.1) ENST00000563390
    ENST00000574723 ENST00000575669 ENST00000576436(uc002dfk.1) ENST00000562935
    ENST00000569365 ENST00000576008(uc002dfj.1) ENST00000565420 ENST00000563579
    ENST00000569083 ENST00000573554

    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 2): RPS15A
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPS15A
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate RPS15A
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS15A (see all 6)
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS15A
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPS15A (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPS15A (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): RPS15A (NM_001030009)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPS15A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS15A 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RPS15A
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RPS15A
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS15A
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS15A

    Additional cDNA sequence: 

    AB062400.1 AK130967.1 AK291988.1 AK311976.1 AY208299.1 BC001697.2 BC030569.1 BC032115.2 
    BC046113.1 BC068045.1 BC105273.1 BC105292.1 X84407.1 

    24/68 DOTS entries (see all 68):

    DT.100059895  DT.91696817  DT.91761690  DT.100718697  DT.100718689  DT.95090964  DT.95297912  DT.100718687 
    DT.100718699  DT.120668760  DT.85102448  DT.100718683  DT.100718696  DT.91845628  DT.100718688  DT.40312693 
    DT.101986466  DT.100758341  DT.100846745  DT.92408336  DT.87077971  DT.100718698  DT.100866116  DT.120668612 

    24/947 AceView cDNA sequences (see all 947):

    CD675175 BE779747 F13229 BE018826 AK130967 AU076529 CB111084 BG685073 
    CB150790 BP359751 BQ423201 BM472716 CR626095 AW392403 AU131595 AA372775 
    D31885 CR590895 AJ705985 BC046113 CR612657 AU132094 BM697727 BM795860 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RPS15A    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6
    SP1:        -                           
    SP2:                    -               
    SP3:                                    


    ECgene alternative splicing isoforms for RPS15A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPS15A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    RPS15A expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Endoderm-like cells (Generation of hepato...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RPS15A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPS15A

    SOURCE GeneReport for Unigene cluster: Hs.370504
        SABiosciences Custom PCR Arrays for RPS15A
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RPS15A
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RPS15A
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS15A
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS15A
    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS15A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS15A gene from 10/41 species (see all 41)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rps15a1 , 5 ribosomal protein S15A1, 5 87.69(n)1
    100(a)1
      7 (63.44 cM)5
    2670191  NM_170669.21  NP_733769.11 
     1181058285 
    chicken
    (Gallus gallus)
    Aves RPS15A1 ribosomal protein S15a 86.41(n)
    99.23(a)
      427675  XM_003642122.1  XP_003642170.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPS15A6
    --
    --
    96(a)
    93(a)
    many → 1
    many → 1
    GL343304.1(485870-486262)
    AAWZ02037778(4553-4945)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480167052   -- 83.71(n)    48016705 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb04b072 Transcribed sequence with strong similarity to protein more 82.56(n)    CK396126.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpS15A3
    RpS15Aa1
    protein biosynthesis structural constituent
    of more3
    Ribosomal protein S15Aa1
    88(a)
    (best of 2)3
    74.1(n)1
    88.46(a)1
      11E113
    441501  NM_167363.21  NP_727693.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rps-221 , 3 40S ribosomal protein3
    Protein RPS-221
    86(a)3
    69.49(n)1
    86.15(a)1
      III(2022309-2023258)3
    1753381  NM_065080.41  NP_497481.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPS22A(YJL190C)4
    RPS22A1
    Protein component of the small (40S) ribosomal subunit; more4
    Rps22ap1
    67.18(n)1
    76.92(a)1
      10(75302-74910)4
    8532491, 4  NP_012345.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RPS15AD1 40S ribosomal protein S15a-4 72.05(n)
    77.69(a)
      823747  NM_114473.5  NP_190190.1 
    rice
    (Oryza sativa)
    Liliopsida Os07g02080001 hypothetical protein 69.74(n)
    77.69(a)
      4342697  NM_001065695.1  NP_001059160.1 


    ENSEMBL Gene Tree for RPS15A (if available)
    TreeFam Gene Tree for RPS15A (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPS15A gene
    1 SIMAP similar gene for RPS15A using alignment to 7 protein entries:     RS15A_HUMAN (see all proteins):
    APOPT1

    RPS15A for paralogs           About GeneDecksing


    5/44 Pseudogenes.org Pseudogenes for RPS15A (see all 44)
    PGOHUM00000238515 PGOHUM00000238618 PGOHUM00000238924 PGOHUM00000238942 PGOHUM00000262181


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/170 NCBI SNPs in RPS15A are shown (see all 170    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1846521461,2
    --18793829(+) CACTTG/TAGGCC 2 -- ds50010--------
    rs26065651,2
    C,F,A,--18793843(-) GGTCTT/CGAGTT 2 -- ds500110Minor allele frequency- C:0.25NA WA CSA EA 372
    rs26065641,2
    C,F,A,H,--18793903(-) CCACAT/CCCGGC 2 -- ds50019Minor allele frequency- C:0.27NA WA CSA EA 370
    rs1436622981,2
    --18794000(+) GATCGC/TGCCAC 2 -- ds50010--------
    rs560085651,2
    C--18794052(+) AAAAA-/ACTGAA 2 -- ds50011Minor allele frequency- A:0.00NA 2
    rs129267691,2
    C,F,H--18794080(+) TACAAC/TTAAAA 2 -- ds50017Minor allele frequency- T:0.01NS EA NA 696
    rs1894169011,2
    --18794127(+) GGGGTA/GACTGT 2 -- ds50010--------
    rs561389381,2
    C--18794248(+) GGCTAC/TACTGC 2 -- ds50010--------
    rs1471864741,2
    C,--18794453(+) CTGGTA/GAGTTT 2 -- int10--------
    rs772487881,2
    --18794498(+) ACATCA/TACACT 2 -- int11Minor allele frequency- T:0.01WA 118

    HapMap Linkage Disequilibrium report for RPS15A (18792617 - 18801705 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for RPS15A
         3 CNVs: 3994 8816 3112

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPS15A
    DNA2.0 Custom Variant and Variant Library Synthesis for RPS15A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RPS15A for disorders           About GeneDecksing

    OMIM gene information: 603674    OMIM disorders: --

    6 diseases for RPS15A:    About MalaCards
    diamond-blackfan anemia    newcastle disease    hepatitis b    anemia
    hepatitis    malaria

    1 disease from the University of Copenhagen DISEASES database for RPS15A:
    Newcastle disease

    Export disorders for RPS15A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPS15A gene, integrated from 9 sources (see all 43):
    (articles sorted by number of sources associating them with RPS15A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (1996)
    4. The primary structure of rat ribosomal protein S15a. (PubMed id 8185605)1, 2 Chan Y.-L.... Wool I.G. (1994)
    5. Human S15a expression is upregulated by hepatitis B virus X protein. (PubMed id 15108328)1, 9 Lian Z....Feitelson M.A. (2004)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    10. The interaction of the von Hippel-Lindau tumor suppres sor and heterochromatin protein 1. (PubMed id 22234250)1 Lai Y....Shiio Y. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6210 HGNC: 10389 AceView: RPS15AandARL6IP Ensembl:ENSG00000134419 euGenes: HUgn6210
    ECgene: RPS15A Kegg: 6210 H-InvDB: RPS15A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPS15A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPS15A gene:
    Search GeneIP for patents involving RPS15A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   Browse OriGene shRNA RFPs  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS15A   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RPS15A  
     OriGene Protein Over-expression Lysate for RPS15A   Browse OriGene Fluorogenic Cell Assay Kits  
     Browse OriGene siRNAs   OriGene 3'-UTR Clone for RPS15A  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPS15A   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPS15A  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RPS15A   OriGene Custom Protein Services for RPS15A  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RPS15A
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPS15A
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS15A
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS15A
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS15A
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS15A
     GenScript Custom Purified and Recombinant Proteins Services for RPS15A GenScript cDNA clones with any tag delivered in your preferred vector for RPS15A
     GenScript Custom Assay Services for RPS15A GenScript Custom Superior Antibodies Services for RPS15A
     GenScript Custom overexpressing Cell Line Services for RPS15A CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in RPS15A promoter
     Search Chromatin IP Primers for RPS15A
     RT2 qPCR Primer Assay in human, mouse, rat RPS15A
     Search GNC Networks for RPS15A
     SABiosciences Custom PCR Arrays for RPS15A
     Search Tocris compounds for RPS15A
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     RPS15A antibodies
     RPS15A proteins
     RPS15A lysates
     Search for Antibodies for RPS15A at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for RPS15A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     RPS15A Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for RPS15A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPS15A
     Browse SwitchGear 3'UTR luciferase reporter plasmids for RPS15A
     SwitchGear Promoter luciferase reporter plasmids for RPS15A
     ThermoFisher Antibody for RPS15A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPS15A
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RPS15A gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4