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RPS15A Gene

protein-coding   GIFtS: 62
GCID: GC16M018701

Ribosomal Protein S15a

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein S15a1 2
40S Ribosomal Protein S15a2
S15a2
Up-Regulated By HBV X Protein2

External Ids:    HGNC: 103891   Entrez Gene: 62102   Ensembl: ENSG000001344197   OMIM: 6036745   UniProtKB: P622443   

Export aliases for RPS15A gene to outside databases

Previous GC identifers: GC16M018285 GC16M018721 GC16M018760 GC16M017336


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPS15A Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8P family of
ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there
are multiple processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPS15A Gene:
RPS15A (ribosomal protein S15a) is a protein-coding gene. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for RPS15A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_187260.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPS15A gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   YY1   E2F-1   E2F   POU2F1   POU2F1a   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS15A promoter sequence
   Search Chromatin IP Primers for RPS15A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPS15A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p   Ensembl cytogenetic band:  16p12.3   HGNC cytogenetic band: 16p12.3

RPS15A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS15A gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M018701:  view genomic region     (about GC identifiers)

Start:
18,792,617 bp from pter      End:
18,801,705 bp from pter
Size:
9,089 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RS15A_HUMAN, P62244 (See protein sequence)
Recommended Name: 40S ribosomal protein S15a  
Size: 130 amino acids; 14840 Da
Sequence caution: Sequence=CAA44568.1; Type=Frameshift; Positions=24, 37;
1 PDB 3D structure from and Proteopedia for RPS15A:
3J3A (3D)    
Secondary accessions: P39027 P39031 Q3MHD9 Q8C023 Q9BV24

Explore the universe of human proteins at neXtProt for RPS15A: NX_P62244

Explore proteomics data for RPS15A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys12, Lys19, Lys32, Lys60, Lys71, Lys84, Lys88, Lys124
  • Modification sites at PhosphoSitePlus

  • See RPS15A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001010.2  NP_001025180.1  

    ENSEMBL proteins: 
     ENSP00000318646   ENSP00000458528   ENSP00000457000   ENSP00000460069   ENSP00000459554  
     ENSP00000457001   ENSP00000457924   ENSP00000459373   ENSP00000458115   ENSP00000458052  
     ENSP00000460618  
    Reactome Protein details: P62244

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPS: S ribosomal proteins

    1 InterPro protein domain:
     IPR000630 Ribosomal_S8

    Graphical View of Domain Structure for InterPro Entry P62244

    ProtoNet protein and cluster: P62244

    1 Blocks protein domain: IPB000630 Ribosomal protein S8

    UniProtKB/Swiss-Prot: RS15A_HUMAN, P62244
    Similarity: Belongs to the ribosomal protein S8P family


    Find genes that share domains with RPS15A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPS15A:
    60S ribosomal protein S15A

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding NAS9582194
    GO:0003735structural constituent of ribosome NAS9582194
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with RPS15A           About GenesLikeMe


    Phenotypes:
         5 GenomeRNAi human phenotypes for RPS15A:
     Decreased Hepatitis C virus re  Decreased cell number  Decreased viability  Decreased viability of wild-ty 
     Increased gamma-H2AX phosphory 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RPS15A

    miRNA
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    hsa-mir-100-5p (MIRT048568), hsa-mir-27b-3p (MIRT046168), hsa-mir-17-5p (MIRT050832), hsa-mir-455-3p (MIRT037867), hsa-let-7a-5p (MIRT052449), hsa-mir-423-5p (MIRT038026), hsa-mir-92a-3p (MIRT049566)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    mitochondrion2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA15108328
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022627cytosolic small ribosomal subunit IDA15883184
    GO:0070062extracellular vesicular exosome IDA--

    Find genes that share ontologies with RPS15A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPS15A About   (see all 6)  
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
    Translation initiation complex formation0.91
    Ribosomal scanning and start codon recognition0.91
    Formation of the ternary complex, and subsequently, the 43S complex0.91
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.90
    4Gene Expression
    Gene Expression0.40
    5Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30


    Find genes that share SuperPaths with RPS15A           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS15A
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS15A
        Cytoplasmic Ribosomal Proteins

    Selected Reactome Pathways for RPS15A (see all 12)
        Peptide chain elongation
    Formation of the ternary complex, and subsequently, the 43S complex
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit


    1 Kegg Pathway  (Kegg details for RPS15A):
        Ribosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPS15A
    Interactions:

        Search GeneGlobe Interaction Network for RPS15A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPS15A (P622441, 2, 3 ENSP000003186464) via UniProtKB, MINT, STRING, and/or I2D (see all 624)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000215425Q138381, 2, 3EBI-347895,EBI-348622 MINT-62817 MINT-62741 MINT-62643 I2D: score=4 
    ENSG00000225859Q138381, 2, 3EBI-347895,EBI-348622 MINT-62817 MINT-62741 MINT-62643 I2D: score=4 
    ENSG00000229496Q138381, 2, 3EBI-347895,EBI-348622 MINT-62817 MINT-62741 MINT-62643 I2D: score=4 
    ENSG00000230624Q138381, 2, 3EBI-347895,EBI-348622 MINT-62817 MINT-62741 MINT-62643 I2D: score=4 
    ENSG00000235439Q138381, 2, 3EBI-347895,EBI-348622 MINT-62817 MINT-62741 MINT-62643 I2D: score=4 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 16):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    Find genes that share ontologies with RPS15A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPS15A (RS15A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RPS15A gene (2 alternative transcripts): 
    NM_001019.4  NM_001030009.1  

    Unigene Cluster for RPS15A:

    Ribosomal protein S15a
    Hs.370504  [show with all ESTs]
    Unigene Representative Sequence: BM907705
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322989(uc002dfh.1) ENST00000572008(uc002dfi.1) ENST00000563390
    ENST00000574723 ENST00000575669 ENST00000576436(uc002dfk.1) ENST00000562935
    ENST00000569365 ENST00000576008(uc002dfj.1) ENST00000565420 ENST00000563579
    ENST00000569083 ENST00000573554
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      QuantiTect SYBR Green Assays in human, mouse, rat RPS15A
      QuantiFast Probe-based Assays in human, mouse, rat RPS15A

    Additional mRNA sequence: 

    AB062400.1 AK130967.1 AK291988.1 AK311976.1 AY208299.1 BC001697.2 BC030569.1 BC032115.2 
    BC046113.1 BC068045.1 BC105273.1 BC105292.1 X84407.1 

    Selected DOTS entries (see all 67):

    DT.100059895  DT.91696817  DT.91761690  DT.100718697  DT.100718689  DT.95090964  DT.95297912  DT.100718687 
    DT.100718699  DT.120668760  DT.85102448  DT.100718683  DT.100718696  DT.91845628  DT.100718688  DT.40312693 
    DT.100758341  DT.100846745  DT.92408336  DT.101986466  DT.87077971  DT.100718698  DT.100866116  DT.120668612 

    Selected AceView cDNA sequences (see all 947):

    F27245 D31244 AW273036 BU675196 BX488101 BM828034 BG106205 BQ348961 
    BE780109 CB132453 AL119666 AU118040 AA378363 BM833709 BG924545 AI735235 
    CF272418 AW263138 AA595626 F25746 CB143494 AA843976 AI566340 BU155963 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RPS15A    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6
    SP1:        -                           
    SP2:                    -               
    SP3:                                    


    ECgene alternative splicing isoforms for RPS15A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPS15A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RPS15A Expression
    About this image


    RPS15A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Endoderm (Gastrulation Derivatives)
             Endoderm-like cells
    RPS15A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPS15A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.370504
        Custom PCR Arrays for RPS15A
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS15A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS15A gene from Selected species (see all 28)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rps15a1 , 5 ribosomal protein S15A1, 5 87.69(n)1
    100(a)1
      7 (63.44 cM)5
    2670191  NM_170669.21  NP_733769.11 
     1181058285 
    chicken
    (Gallus gallus)
    Aves RPS15A1 ribosomal protein S15a 86.41(n)
    99.23(a)
      427675  XM_003642122.2  XP_003642170.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    96(a)
    1 → many
    GL343304.1(485870-486262)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480167052   -- 83.71(n)    48016705 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb04b072 Transcribed sequence with strong similarity to protein more 82.56(n)    CK396126.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpS15A3
    RpS15Aa1
    protein biosynthesis structural
    constituent of more3
    Ribosomal protein S15Aa1
    88(a)
    (best of 2)3
    74.1(n)1
    88.46(a)1
      11E113
    441501  NM_167363.21  NP_727693.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rps-221 , 3 40S ribosomal protein3
    rps-221
    86(a)3
    69.49(n)1
    86.15(a)1
      III(2022309-2023258)3
    1753381  NM_065080.51  NP_497481.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPS22A(YJL190C)4
    RPS22A1
    Protein component of the small (40S) ribosomal subunit; more4
    RPS22A1
    67.18(n)1
    76.92(a)1
      10(75302-74910)4
    8532491, 4  NP_012345.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G395901 AT2G39590 68.97(n)
    73.08(a)
      818544  NM_129517.1  NP_181491.1 
    barley
    (Hordeum vulgare)
    Liliopsida AJ464968.12   -- 77.87(n)    AJ464968.1 


    ENSEMBL Gene Tree for RPS15A (if available)
    TreeFam Gene Tree for RPS15A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPS15A gene
    1 SIMAP similar gene for RPS15A using alignment to 7 protein entries:     RS15A_HUMAN (see all proteins):
    APOPT1

    Find genes that share paralogs with RPS15A           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for RPS15A (see all 44)
    PGOHUM00000238515 PGOHUM00000238618 PGOHUM00000238924 PGOHUM00000238942 PGOHUM00000262181


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPS15A (see all 208)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1846521461,2
    --18793829(+) CACTTG/TAGGCC 2 -- ds50010--------
    rs26065651,2
    C,F,A--18793843(-) GGTCTT/CGAGTT 2 -- ds500110Minor allele frequency- C:0.25NA WA CSA EA 372
    rs26065641,2
    C,F,A,H--18793903(-) CCACAT/CCCGGC 2 -- ds50019Minor allele frequency- C:0.27NA WA CSA EA 370
    rs1436622981,2
    --18794000(+) GATCGC/TGCCAC 2 -- ds50010--------
    rs560085651,2
    C--18794052(+) AAAAG-/A/AA  
            
    AAAAA
    2 -- ds50012NA 4
    rs129267691,2
    C,F,H--18794080(+) TACAAC/TTAAAA 2 -- ds50017Minor allele frequency- T:0.01NS EA NA 696
    rs1894169011,2
    --18794127(+) GGGGTA/GACTGT 2 -- ds50010--------
    rs561389381,2
    C--18794248(+) GGCTAC/TACTGC 2 -- ds50010--------
    rs2010616441,2
    C--18794328(+) TTACAT/ACCCTA 2 -- ut311Minor allele frequency- A:0.00EU 1163
    rs1471864741,2
    C--18794453(+) CTGGTA/GAGTTT 2 -- int10--------

    HapMap Linkage Disequilibrium report for RPS15A (18792617 - 18801705 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for RPS15A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv428320CNV Loss18775914
    nsv833161CNV Loss17160897
    nsv469598CNV Gain16826518
    esv34419CNV Gain17911159
    esv587CNV CNV17122850
    dgv823e1CNV Complex17122850
    dgv822e1CNV Complex17122850
    dgv825e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPS15A
    DNA2.0 Custom Variant and Variant Library Synthesis for RPS15A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603674    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for RPS15A:
    Newcastle disease

    Find genes that share disorders with RPS15A           About GenesLikeMe


    Export disorders for RPS15A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPS15A gene, integrated from 10 sources (see all 53):
    (articles sorted by number of sources associating them with RPS15A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (Genome Res. 1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (Eur. J. Biochem. 1996)
    4. The primary structure of rat ribosomal protein S15a. (PubMed id 8185605)1, 2 Chan Y.-L.... Wool I.G. (Biochem. Biophys. Res. Commun. 1994)
    5. Human S15a expression is upregulated by hepatitis B virus X protein. (PubMed id 15108328)1, 9 Lian Z....Feitelson M.A. (Mol. Carcinog. 2004)
    6. Down-regulation of ribosomal protein S15A mRNA with a short hairpin RNA inhibits human hepatic cancer cell growth in vitro. (PubMed id 24334120)1 Xu M....Chen G. (Gene 2014)
    7. A Proteomics Strategy for the Identification of FAT10-Modified Sites by Mass Spectrometry. (PubMed id 23862649)1 Leng L....Wang J. (J. Proteome Res. 2014)
    8. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    9. Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation. (PubMed id 23184937)1 Xie Y....Cong F. (J. Biol. Chem. 2013)
    10. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6210 HGNC: 10389 AceView: RPS15AandARL6IP Ensembl:ENSG00000134419 euGenes: HUgn6210
    ECgene: RPS15A Kegg: 6210 H-InvDB: RPS15A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RPS15A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPS15A gene:
    Search GeneIP for patents involving RPS15A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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