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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPS13 Gene

protein-coding   GIFtS: 60
GCID: GC11M017055

ribosomal protein S13
 Explore 2 diseases affiliated with
RPS13 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RPS13    

Aliases
for RPS13 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Ribosomal Protein S131 2
S131 2
40S Ribosomal Protein S132

External Ids:    HGNC: 103861   Entrez Gene: 62072   Ensembl: ENSG000001107007   OMIM: 1804765   UniProtKB: P622773   

Export aliases for RPS13 gene to outside databases

Previous GC identifers: GC11M018166 GC11M018039 GC11M017135 GC11M017060 GC11M017054 GC11M016780


Summaries
for RPS13 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RPS13:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene
encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S15P family of
ribosomal proteins. It is located in the cytoplasm. The protein has been shown to bind to the 5.8S rRNA in rat. The
gene product of the E. coli ortholog (ribosomal protein S15) functions at early steps in ribosome assembly. This gene
is co-transcribed with two U14 small nucleolar RNA genes, which are located in its third and fifth introns. As is
typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through
the genome. (provided by RefSeq, Jul 2008)

Gene Wiki entry for RPS13


Genomic Views
for RPS13 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_009237.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPS13 gene promoter:
         Nkx3-1   AP-2rep   p53   AP-1   Nkx3-1 v1   YY1   GATA-1   Nkx3-1 v2   Ik-2   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RPS13 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPS13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15   Ensembl cytogenetic band:  11p15.1   HGNC cytogenetic band: 11p

RPS13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS13 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M017055:  view genomic region     (about GC identifiers)

Start:
 17,095,936 bp from pter      End:
 17,099,334 bp from pter
Size:
 3,399 bases      Orientation:
 minus strand

Proteins
for RPS13 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RS13_HUMAN, P62277 (See protein sequence)
Recommended Name: 40S ribosomal protein S13  
Size: 151 amino acids; 17222 Da
Secondary accessions: B2R549 P19116 Q02546 Q29200 Q498Y0

Explore the universe of human proteins at neXtProt for RPS13: NX_P62277

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P62277

    • RPS13 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001008.1  
    ENSEMBL proteins: 
     ENSP00000228140   ENSP00000435777   ENSP00000432096  
    Reactome Protein details: P62277
    Human Recombinant Protein Products: 
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    Novus Biologicals RPS13 Protein
    Browse Sino Biological Recombinant Proteins
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    Uscn Proteins for RPS13

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view) (see first 5):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA17881366
    GO:0005730nucleolus IDA17881366
    GO:0005829cytosol TAS--
    GO:0005840ribosome NAS8332508
    GO:0022627cytosolic small ribosomal subunit IDA8706699


    RPS13 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for RPS13

    Protein Domains /
    Families
    for RPS13 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RPS13 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR023029 Ribosomal_S15P
     IPR012606 Ribosomal_S13/S15_N
     IPR000589 Ribosomal_S15
     IPR009068 S15_NS1_RNA-bd

    Graphical View of Domain Structure for InterPro Entry P62277

    ProtoNet protein and cluster: P62277

    1 Blocks protein family: IPB012606 Ribosomal S13S15 N-terminal

    UniProtKB/Swiss-Prot: RS13_HUMAN, P62277
    Similarity: Belongs to the ribosomal protein S15P family


    Function
    for RPS13 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
         Genatlas biochemistry entry for RPS13:
    60S ribosomal protein S13

    miRNA
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    Gene Editing
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    Clone
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    Search LifeMap BioReagents cell lines for RPS13

    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003729mRNA binding IDA17881366
    GO:0003735structural constituent of ribosome IEA--
    GO:0005515protein binding IPI12054647


    RPS13 for ontologies           About GeneDecksing


    7 GenomeRNAi human phenotypes for RPS13:
     Decreased Hepatitis C virus re  Decreased cell number  Decreased viability  Decreased viability of wild-ty 
     Increased cell number in G2M,   Nuclear 40S maturation defects  Nucleolar pre-40S maturation d 


    Pathways & Interactions
    for RPS13 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    		Viral Protein Synthesis1.00
    		Cytoplasmic Ribosomal Proteins0.86
    		Viral mRNA Translation1.00
    		CFTR translational fidelity (class I mutations)0.83
    		Influenza Viral RNA Transcription and Replication1.00
    		SMG6 Cleaves mRNA with Premature Termination Codon0.80
    		Synthesis of nascent polypeptide containing signal sequence1.00
    		L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Translation initiation complex formation
    		Translation initiation complex formation1.00
    		Ribosomal scanning and start codon recognition0.96
    		Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.98
    		Formation of the ternary complex, and subsequently, the 43S complex0.87
    3Metabolism of mRNA
    		Metabolism of mRNA1.00
    		Metabolism of RNA0.92
    4Disease
    		Disease1.00
    5TNF-alpha/NF-kB Signaling Pathway
    		TNF-alpha/NF-kB Signaling Pathway1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS13
        CFTR translational fidelity (class I mutations)

    2 BioSystems Pathways for RPS13 
        Cytoplasmic Ribosomal Proteins
    TNF-alpha/NF-kB Signaling Pathway

    5/32        Reactome Pathways for RPS13 (see all 32)
        Formation of a pool of free 40S subunits
    Synthesis of PB1-F2
    SMG6 Cleaves mRNA with Premature Termination Codon
    Influenza Life Cycle
    Viral mRNA Translation


    1         Kegg Pathway  (Kegg details for RPS13):
        Ribosome


    RPS13 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RPS13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/953 Interacting proteins for RPS13 (P622771, 2, 3 ENSP000002281404) via UniProtKB, MINT, STRING, and/or I2D (see all 953)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL8P629172, 3, ENSP000002625844MINT-6542674 MINT-6489539 MINT-6488791 I2D: score=2 STRING: ENSP00000262584
    RPL11P629132, 3, ENSP000003636764MINT-6542674 MINT-6489539 MINT-6488791 I2D: score=1 STRING: ENSP00000363676
    RPL12P300502, 3, ENSP000003547394MINT-6542674 MINT-6489539 MINT-6488791 I2D: score=1 STRING: ENSP00000354739
    RPL13P263732, 3, ENSP000003078894MINT-6542674 MINT-7947479 MINT-6488791 I2D: score=1 STRING: ENSP00000307889
    RPL26P612542, 3, ENSP000002938424MINT-6542674 MINT-6489539 MINT-6488791 I2D: score=1 STRING: ENSP00000293842
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--


    RPS13 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RPS13 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPS13
    Search CenterWatch for drugs/clinical trials and news about RPS13 / RS13 

    Transcripts
    for RPS13 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RPS13 gene: 
    NM_001017.2  

    Unigene Cluster for RPS13:

    Ribosomal protein S13
    Hs.446588  [show with all ESTs]
    Unigene Representative Sequence: BE621497
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000531008 ENST00000531908 ENST00000228140 ENST00000526895 ENST00000525634(uc001mmp.3)
    ENST00000525828 ENST00000533969 ENST00000527571 ENST00000534329 ENST00000528074


    miRNA
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPS13 (see all 7)
    OriGene shRNA RFP: RPS13
    OriGene siRNA: RPS13
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPS13
    Clone
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    Additional cDNA sequence: 

    AK312060.1 BC000475.1 BC006772.1 BC029732.1 BC066322.1 BC100032.1 L01124.1 L05090.1 
    X79239.1 

    24/45 DOTS entries (see all 45):

    DT.100034195  DT.91780893  DT.91780905  DT.100060141  DT.95377158  DT.97814138  DT.100689183  DT.120736380 
    DT.100689171  DT.120736387  DT.100689181  DT.120736393  DT.100060137  DT.121431383  DT.100689168  DT.100689186 
    DT.120736385  DT.120736420  DT.121431378  DT.421641  DT.85101328  DT.91780895  DT.100689175  DT.120736415 

    24/1408 AceView cDNA sequences (see all 1408):

    BM841621 BQ277838 T69927 AA381436 BM006169 CN485114 AI124967 NR_001452 
    F21917 CD677360 BG686936 CA843734 BM758837 AA317959 AW474405 CB113644 
    AV712079 AA353627 BQ353162 BF032207 BM817860 BG289197 BG474759 H80045 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RPS13    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5 ^ 6
    SP1:                                                                        
    SP2:                                      -     -     -                     
    SP3:                                                                        
    SP4:                                                                        
    SP5:                                                                        


    ECgene alternative splicing isoforms for RPS13

    Expression
    for RPS13 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPS13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTGTTGCACA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    RPS13 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryPrimary FolliclePrimary OocyteFemale Gametocytes, Germ Cells
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RPS13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPS13

    SOURCE GeneReport for Unigene cluster: Hs.446588
        SABiosciences Custom PCR Arrays for RPS13
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    In Situ
    Assay Products:     
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    Orthologs
    for RPS13 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS13 gene from 9/38 species (see all 38)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Rps131 , 5 ribosomal protein S131, 5 86.98(n)1
    100(a)1    		   7 (61.61 cM)5
    680521  NM_026533.31  NP_080809.11 
     1163315075 
    chicken
    (Gallus gallus)    		 Aves RPS131 ribosomal protein S13 81.68(n)
    100(a)    		   414782  NM_001001783.1  NP_001001783.1 
    lizard
    (Anolis carolinensis)    		 Reptilia RPS136
    		 --
    		 100(a)
    		 1 ↔ 1
    		 1(66624651-66629484)
    African clawed frog
    (Xenopus laevis)    		 Amphibia rps13-prov2 ribosomal protein S13 81.14(n)    BC056028.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii 570848262   -- 78.84(n)    57084826 
    fruit fly
    (Drosophila melanogaster)    		 Insecta RpS131 , 3 protein biosynthesis structural constituent
    of more3
    Ribosomal protein S131    		 87(a)3
    71.08(n)1
    87.42(a)1    		   2 29B23
    341491  NM_001038796.21  NP_001033885.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea rps-131 , 3 40S ribosomal protein S133
    Protein RPS-131    		 76(a)3
    68.43(n)1
    76.16(a)1    		   III(6445813-6446906)3
    1759011  NM_065992.41  NP_498393.11 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons ATRPS13A6
    AT3G607706
    		 40S ribosomal protein S13-1
    		 79(a)
    78(a)
    		 many → 1
    many → 1
    		 4(37084-38312)
    3(22460189-22461779)
    rice
    (Oryza sativa)    		 Liliopsida Os.151682 Oryza sativa (japonica cultivar-group) cDNA clone0 more 71.08(n)    AK059505.1 


    ENSEMBL Gene Tree for RPS13 (if available)
    TreeFam Gene Tree for RPS13 (if available) 

    Paralogs
    for RPS13 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPS13 gene
    18/41 SIMAP similar genes for RPS13 using alignment to 3 protein entries:     RS13_HUMAN (see all proteins) (see all similar genes):
    RRM2B    EIF3G    LSM12    C12orf76    UBXN4    ADCK1
    EIF3K    DOCK8    FLJ00047    EEF1E1    GALK2    PFKFB3
    C21orf37    DYNC2LI1    COQ5    NCKAP1L    SH2B3    RHBG

    RPS13 for paralogs           About GeneDecksing


    5/11 Pseudogenes.org Pseudogenes for RPS13 (see all 11)
    PGOHUM00000246797 PGOHUM00000247118 PGOHUM00000244031 PGOHUM00000245058 PGOHUM00000239991


    Genomic Variants
    for RPS13 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/109 NCBI SNPs in RPS13 are shown (see all 109)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 11 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1169620131,2
    		--17095486(+) CCTCCA/GGTGAC 1 -- ds50011Minor allele frequency- G:0.01NA 120
    rs110241471,2
    		C,F,A,H,--17095565(+) ATTACT/GTTTGC 1 -- ds500110Minor allele frequency- G:0.20NS EA WA CSA 786
    rs169248991,2
    		C,F,H,--17095596(+) TCTGAT/CGCTAC 1 -- ds500127Minor allele frequency- C:0.18NA NS EA CSA WA EU 3425
    rs1882470661,2
    		--17095686(+) ATGACA/GCCAAA 1 -- ds50010--------
    rs1168494251,2
    		C,F,--17095699(+) AAACAC/AAAAGG 1 -- ds50011Minor allele frequency- A:0.02EA 120
    rs1917830571,2
    		C,--17095934(+) AACATC/GCTTTT 2 -- ds50010--------
    rs1474523421,2
    		C,F,--17095967(+) TTGAGT/AACACA 2 -- ut31 ds50011Minor allele frequency- A:0.01EU 1291
    rs110241481,2
    		C,F,A,H,--17096059(+) ATACTG/AGTCCC 2 -- int1 ds500127Minor allele frequency- A:0.35NA NS EA WA CSA 2727
    rs1840953791,2
    		--17096084(+) CAGAAG/TCTCCC 2 -- ds5001 int10--------
    rs71256071,2
    		C,F,A,H,--17096150(+) AAACTA/TCTGAA 2 -- ds5001 int123Minor allele frequency- T:0.31EA NA NS WA CSA 1509

    HapMap Linkage Disequilibrium report for RPS13 (17095936 - 17099334 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RPS13: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPS13
    DNA2.0 Custom Variant and Variant Library Synthesis for RPS13

    Disorders / Diseases
    for RPS13 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RPS13 for disorders           About GeneDecksing

    OMIM gene information: 180476    OMIM disorders: --

    2 diseases for RPS13:    About MalaCards
    gastric cancer    malaria

    1 Novoseek disease relationship for RPS13 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 2 16761435 (2)


    Export disorders for RPS13 gene to outside databases

    Publications
    for RPS13 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPS13 gene, integrated from 9 sources (see all 70):
    (articles sorted by number of sources associating them with RPS13)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and analysis of the human S13 ribosomal protein cDNA. (PubMed id 8332508)1, 2, 3 Chadeneau C.... Denis M.G. (1993)
    2. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 3 Kenmochi N.... Page D.C. (1998)
    5. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (1996)
    6. U14 snoRNAs are encoded in introns of human ribosomal protein S13 gene. (PubMed id 8920921)1, 2 Kenmochi N.... Tanaka T. (1996)
    7. Human ribosomal protein S13 regulates expression of its own gene at the splicing step by a feedback mechanism. (PubMed id 17881366)1, 9 Malygin A.A....Karpova G.G. (2007)
    8. Human ribosomal protein S13: cloning, expression, refolding, and structural stability. (PubMed id 15680243)1, 9 Malygin A....Karpova G. (2005)
    9. Ribosomal proteins S13 and L23 promote multidrug resistance in gastric cancer cells by suppressing drug-induced apoptosis. (PubMed id 15149863)1, 9 Shi Y....Fan D. (2004)
    10. The human EKC/KEOPS complex is recruited to Cullin2 ub iquitin ligases by the human tumour antigen PRAME. (PubMed id 22912744)1 Costessi A....Stunnenberg H.G. (2012)

    External Searches for RPS13 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing RPS13 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6207 HGNC: 10386 AceView: RPS13 Ensembl:ENSG00000110700 euGenes: HUgn6207
    ECgene: RPS13 Kegg: 6207 H-InvDB: RPS13

    Other Databases showing RPS13 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RPS13 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPS13 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for RPS13 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RPS13 gene:
    Search GeneIP for patents involving RPS13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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