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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPS12 Gene

protein-coding   GIFtS: 62
GCID: GC06P133136

Ribosomal Protein S12

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ribosomal Protein S121 2
40S Ribosomal Protein S122
S122

External Ids:    HGNC: 103851   Entrez Gene: 62062   Ensembl: ENSG000001123067   OMIM: 6036605   UniProtKB: P253983   

Export aliases for RPS12 gene to outside databases

Previous GC identifers: GC06P132758 GC06P132982 GC06P133116 GC06P133177 GC06P130710


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RPS12 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12E family
of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal cancers
compared to matched normal colonic mucosa has been observed. As is typical for genes encoding ribosomal proteins,
there are multiple processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul
2008)

GeneCards Summary for RPS12 Gene: 
RPS12 (ribosomal protein S12) is a protein-coding gene. Diseases associated with RPS12 include colorectal cancer, and diphtheria, and among its related super-pathways are Eukaryotic Translation Initiation and Formation of the ternary complex, and subsequently, the 43S complex. GO annotations related to this gene include structural constituent of ribosome and molecular_function.

Gene Wiki entry for RPS12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_025741.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPS12 gene promoter:
         GR   Brachyury   FOXO3   FOXO3b   YY1   PPAR-gamma1   FOXO3a   c-Myb   GR-alpha   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS12 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPS12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q23.2   Ensembl cytogenetic band:  6q23.2   HGNC cytogenetic band: 6q23

RPS12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS12 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P133136:  view genomic region     (about GC identifiers)

Start:
133,135,580 bp from pter      End:
133,138,703 bp from pter
Size:
3,124 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RS12_HUMAN, P25398 (See protein sequence)
Recommended Name: 40S ribosomal protein S12  
Size: 132 amino acids; 14515 Da
Subcellular location: Cytoplasm
1 PDB 3D structure from and Proteopedia for RPS12:
3J3A (3D)    
Secondary accessions: Q76M58

Explore the universe of human proteins at neXtProt for RPS12: NX_P25398

Explore proteomics data for RPS12 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P25398

  • RPS12 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RPS12 Protein Expression
    REFSEQ proteins: NP_001007.2  
    ENSEMBL proteins: 
     ENSP00000230050  
    Reactome Protein details: P25398
    Human Recombinant Protein Products for RPS12: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RPS12 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0022627cytosolic small ribosomal subunit NAS1861993

    RPS12 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RPS: S ribosomal proteins

    2 InterPro protein domains:
     IPR000530 Ribosomal_S12e
     IPR004038 Ribosomal_L7Ae/L30e/S12e/Gad45

    Graphical View of Domain Structure for InterPro Entry P25398

    ProtoNet protein and cluster: P25398

    2 Blocks protein domains:
    IPB000530 Ribosomal protein S12E
    IPB004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45


    UniProtKB/Swiss-Prot: RS12_HUMAN, P25398
    Similarity: Belongs to the ribosomal protein S12e family


    RPS12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for RPS12:
    60S ribosomal protein S12

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0003735structural constituent of ribosome IEA--
         
    RPS12 for ontologies           About GeneDecksing


    Phenotypes:
         7 GenomeRNAi human phenotypes for RPS12:
     Cytoplasmic 40S maturation def  Decreased Hepatitis C virus re  Decreased cell number  Decreased viability of wild-ty 
     Nucleolar pre-40S maturation d  S arrest  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RPS12 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RPS12

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RPS12 About   (see all 6)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Viral mRNA Translation
    Influenza Life Cycle0.95
    3' -UTR-mediated translational regulation0.93
    Influenza Infection0.95
    L13a-mediated translational silencing of Ceruloplasmin expression0.93
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Formation of a pool of free 40S subunits0.90
    Eukaryotic Translation Termination0.94
    Nonsense-Mediated Decay0.84
    2Translation initiation complex formation
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.95
    Formation of the ternary complex, and subsequently, the 43S complex0.87
    Ribosomal scanning and start codon recognition0.95
    Translation initiation complex formation0.87
    3Metabolism of mRNA
    Metabolism of mRNA0.92
    Metabolism of RNA0.92
    4Generic Transcription Pathway
    Gene Expression0.47
    5Asparagine N-linked glycosylation
    Metabolism of proteins0.35

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS12
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS12
        Cytoplasmic Ribosomal Proteins

    5/27        Reactome Pathways for RPS12 (see all 27)
        Formation of the ternary complex, and subsequently, the 43S complex
    Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane


    1         Kegg Pathway  (Kegg details for RPS12):
        Ribosome


    RPS12 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPS12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/201 Interacting proteins for RPS12 (P253982, 3 ENSP000002300504) via UniProtKB, MINT, STRING, and/or I2D (see all 201)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPS17P087082, 3, ENSP000003460454MINT-8044024 I2D: score=2 STRING: ENSP00000346045
    MAP3K14Q995582, 3MINT-48843 I2D: score=2 
    ENSG00000096150P622692, 3, ENSP000002113724MINT-8395092 I2D: score=1 STRING: ENSP00000211372
    ENSG00000223367P622692, 3, ENSP000004125834MINT-8395092 I2D: score=1 STRING: ENSP00000412583
    ENSG00000226225P622692, 3, ENSP000004031754MINT-8395092 I2D: score=1 STRING: ENSP00000403175
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPS12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RPS12 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPS12 (RS12)

    4 Novoseek inferred chemical compound relationships for RPS12 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    streptomycin 73.2 8 1725261 (1), 17238915 (1), 9634793 (1), 10645439 (1) (see all 6)
    kanamycin 52.2 1 17052696 (1)
    nadh 49.7 6 11920594 (2), 1865874 (1), 10355121 (1), 7476853 (1) (see all 5)
    glucose 0 1 9747975 (1)

    Search CenterWatch for drugs/clinical trials and news about RPS12 / RS12

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPS12 gene: 
    NM_001016.3  

    Unigene Cluster for RPS12:

    Ribosomal protein S12
    Hs.546289  [show with all ESTs]
    Unigene Representative Sequence: BC002550
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000230050(uc003qdx.3) ENST00000484616
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    Inhib. RNA
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    Additional mRNA sequence: 

    AK311826.1 BC002550.1 BC017321.2 BC071930.1 BC095424.1 X53505.1 

    24/61 DOTS entries (see all 61):

    DT.220499  DT.100711172  DT.100711162  DT.100711165  DT.92325986  DT.95156505  DT.100060132  DT.121388367 
    DT.95156600  DT.121388343  DT.121388399  DT.121388364  DT.40291319  DT.101987342  DT.91650205  DT.100061025 
    DT.100711164  DT.121388401  DT.121388332  DT.87017203  DT.121406732  DT.121388337  DT.91692616  DT.121388349 

    24/1384 AceView cDNA sequences (see all 1384):

    BE874227 CB109349 BU783986 AI339367 CF129175 CF129435 AA974080 AW172641 
    AI707628 CB117458 BP429460 AI720850 N23271 BQ637243 CB110683 BQ066962 
    BU183610 CB149864 BQ643165 AA911050 BM820796 BQ709547 CB109452 CB111677 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for RPS12 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6
    SP1:                                      -                           
    SP2:                          -     -     -                           
    SP3:                                                                  
    SP4:                                      -     -     -     -         
    SP5:                          -     -     -                           


    ECgene alternative splicing isoforms for RPS12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPS12 expression in normal human tissues (normalized intensities)      RPS12 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCGAGGAAG
    RPS12 Expression
    About this image


    RPS12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/22 selected tissues (see all 22) fully expand
     
     Epithelium (Reproductive System)    fully expand to see all 5 entries
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Tonsil (Hematopoietic System)    fully expand to see all 3 entries
             tonsil ; squamous epithelial cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 2 entries
             rectum ; glandular cells   

    See RPS12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPS12

    SOURCE GeneReport for Unigene cluster: Hs.546289
        SABiosciences Custom PCR Arrays for RPS12
    Primer
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS12 gene from 9/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rps121 , 5 ribosomal protein S121, 5 91.41(n)1
    100(a)1
      10 (11.10 cM)5
    200421  NM_011295.61  NP_035425.21 
     237852115 
    chicken
    (Gallus gallus)
    Aves RPS121 ribosomal protein S12 84.34(n)
    99.24(a)
      421698  XM_419736.3  XP_419736.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPS126
    ribosomal protein S12
    98(a)
    1 ↔ 1
    GL343200.1(4366532-4375672)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC685292 hypothetical protein MGC68529 84.49(n)    BC056655.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa95a022 wufa95a02 81.64(n)   337007  BC059433.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpS123 protein biosynthesis structural
    constituent of more
    67(a)     --
    worm
    (Caenorhabditis elegans)
    Secernentea rps-121 , 3 Protein RPS-121 65(a)3
    58.06(n)1
    61.29(a)1
      III(5751105-5751923)3
    1757861  NM_065820.41  NP_498221.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPS12(YOR369C)4
    RPS121
    Protein component of the small (40S) ribosomal subunit; more4
    Rps12p1
    55.36(n)1
    55.65(a)1
      15(1028625-1028194)4
    8545511, 4  NP_015014.31  NP_015014.14 
    rice
    (Oryza sativa)
    Liliopsida Os.229932 Transcribed sequence with weak similarity to protein more 71.1(n)    CA755296.1 


    ENSEMBL Gene Tree for RPS12 (if available)
    TreeFam Gene Tree for RPS12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPS12 gene

    RPS12 for paralogs           About GeneDecksing


    5/33 Pseudogenes.org Pseudogenes for RPS12 (see all 33)
    PGOHUM00000238405 PGOHUM00000238514 PGOHUM00000238561 PGOHUM00000238852 PGOHUM00000242381


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/46 SNPs in RPS12 are shown (see all 46)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1823978991,2
    --133133828(+) GTCTTC/TAGATA 1 -- us2k10--------
    rs1466622561,2
    --133133847(+) TGCGCG/TGAAAG 1 -- us2k10--------
    rs737729611,2
    C,F--133133906(+) CTCCAA/GAAAAG 1 -- us2k13Minor allele frequency- G:0.12WA CSA 122
    rs793338411,2
    C,F--133133938(+) TGCCCC/GTACAC 1 -- us2k11Minor allele frequency- G:0.02NA 120
    rs1403121041,2
    --133133949(+) TTTCAC/TCCATT 1 -- us2k10--------
    rs1501381651,2
    F--133133963(+) AATACC/ACTCCT 1 -- us2k11Minor allele frequency- A:0.03NS 140
    rs1161059471,2
    C,F--133134001(+) CTCTTA/CGTTTT 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1440293501,2
    --133134041(+) AAGCCC/TGAGGT 1 -- us2k10--------
    rs104575941,2
    C,F,A--133134100(+) GTATCT/GCCTCT 1 -- us2k112Minor allele frequency- G:0.35NA WA CSA EA NS 592
    rs1464975721,2
    C--133134136(+) GTCTAA/CAATCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RPS12 (133135580 - 133138703 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for RPS12:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv886676CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603660    OMIM disorders: --

    8 diseases for RPS12:    About MalaCards
    colorectal cancer    diphtheria    tuberculosis    cervicitis
    influenza    retinitis    squamous cell carcinoma    breast cancer


    RPS12 for disorders           About GeneDecksing

    3 Novoseek inferred disease relationships for RPS12 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sterility male 63.8 2 1865874 (1), 10355121 (1)
    tuberculosis 31.4 2 17238915 (1), 19519851 (1)
    cervical cancer 15.1 1 11920594 (1)

    Human Genome Epidemiology (HuGE) Navigator: RPS12 (2 documents)

    Export disorders for RPS12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPS12 gene, integrated from 9 sources (see all 86):
    (articles sorted by number of sources associating them with RPS12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (1998)
    2. cDNA and predicted amino acid sequences of the human ribosomal protein genes rpS12 and rpL17. (PubMed id 1861993)1, 2, 3 Herault Y.... Brun G. (1991)
    3. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (2002)
    4. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (1996)
    5. Identification of molecular markers for the early detection of human squamous cell carcinoma of the uterine cervix. (PubMed id 11870519)1, 9 Cheng Q....Hui K.M. (2002)
    6. Quantitative study of the interactome of PKCz involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (2013)
    7. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (2013)
    8. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    9. Deubiquitinase FAM/USP9X interacts with the E3 ubiquit in ligase SMURF1 protein and protects it from ligase activity-dependent self-deg radation. (PubMed id 23184937)1 Xie Y....Cong F. (2013)
    10. Bcl2-associated Athanogene 3 Interactome Analysis Reve als a New Role in Modulating Proteasome Activity. (PubMed id 23824909)1 Chen Y....Ge F. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6206 HGNC: 10385 AceView: RPS12 Ensembl:ENSG00000112306 euGenes: HUgn6206
    ECgene: RPS12 Kegg: 6206 H-InvDB: RPS12

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPS12 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RPS12 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPS12 gene:
    Search GeneIP for patents involving RPS12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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