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Aliases for RPS10-NUDT3 Gene

Aliases for RPS10-NUDT3 Gene

  • RPS10-NUDT3 Readthrough 2 3

External Ids for RPS10-NUDT3 Gene

Previous GeneCards Identifiers for RPS10-NUDT3 Gene

  • GC06U902178
  • GC06M035243
  • GC06M035740

Summaries for RPS10-NUDT3 Gene

Entrez Gene Summary for RPS10-NUDT3 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring RPS10 (ribosomal protein S10) and NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif 3) genes on chromosome 6. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Feb 2011]

GeneCards Summary for RPS10-NUDT3 Gene

RPS10-NUDT3 (RPS10-NUDT3 Readthrough) is a Protein Coding gene. Among its related pathways are CFTR translational fidelity (class I mutations). An important paralog of this gene is RPS10.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPS10-NUDT3 Gene

Genomics for RPS10-NUDT3 Gene

Genomic Location for RPS10-NUDT3 Gene

34,287,194 bp from pter
34,426,125 bp from pter
138,932 bases
Minus strand

Genomic View for RPS10-NUDT3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RPS10-NUDT3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPS10-NUDT3 Gene

No data available for Regulatory Elements for RPS10-NUDT3 Gene

Proteins for RPS10-NUDT3 Gene

  • Protein details for RPS10-NUDT3 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein RPS10-NUDT3
    Protein Accession:
    Secondary Accessions:

    Protein attributes for RPS10-NUDT3 Gene

    286 amino acids
    Molecular mass:
    32596 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RPS10-NUDT3 Gene

Proteomics data for RPS10-NUDT3 Gene at MOPED

Post-translational modifications for RPS10-NUDT3 Gene

No Post-translational modifications

Other Protein References for RPS10-NUDT3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RPS10-NUDT3 Gene

Domains for RPS10-NUDT3 Gene

Protein Domains for RPS10-NUDT3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RPS10-NUDT3: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RPS10-NUDT3 Gene

Function for RPS10-NUDT3 Gene

Gene Ontology (GO) - Molecular Function for RPS10-NUDT3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016787 hydrolase activity --
genes like me logo Genes that share ontologies with RPS10-NUDT3: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RPS10-NUDT3 Gene

Localization for RPS10-NUDT3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RPS10-NUDT3 Gene

Pathways for RPS10-NUDT3 Gene

SuperPathways for RPS10-NUDT3 Gene

Superpath Contained pathways
1 CFTR translational fidelity (class I mutations)
genes like me logo Genes that share pathways with RPS10-NUDT3: view

Pathways by source for RPS10-NUDT3 Gene

1 KEGG pathway for RPS10-NUDT3 Gene

Interacting Proteins for RPS10-NUDT3 Gene

Gene Ontology (GO) - Biological Process for RPS10-NUDT3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process --
genes like me logo Genes that share ontologies with RPS10-NUDT3: view

Transcripts for RPS10-NUDT3 Gene

mRNA/cDNA for RPS10-NUDT3 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RPS10-NUDT3 Gene

No ASD Table

Relevant External Links for RPS10-NUDT3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RPS10-NUDT3 Gene

mRNA expression in normal human tissues for RPS10-NUDT3 Gene

Protein differential expression in normal tissues for RPS10-NUDT3 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression from for RPS10-NUDT3 Gene

genes like me logo Genes that share expressions with RPS10-NUDT3: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RPS10-NUDT3 Gene

Orthologs for RPS10-NUDT3 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RPS10-NUDT3 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RPS10 35
  • 100 (n)
  • 100 (a)
RPS10-NUDT3 36
  • 90 (a)
(Rattus norvegicus)
Mammalia LOC100361240 35
  • 88.16 (n)
  • 97.37 (a)
(Canis familiaris)
Mammalia -- 36
  • 55 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 87 (a)
(Mus musculus)
Mammalia Rps10 36
  • 93 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 63 (a)
(Gallus gallus)
Aves RPS10 36
  • 93 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 83 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rps10 35
  • 80.48 (n)
  • 96.71 (a)
(Danio rerio)
Actinopterygii rps10 35
  • 78.51 (n)
  • 92.11 (a)
rps10 36
  • 87 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000739 35
  • 63.85 (n)
  • 63.38 (a)
fruit fly
(Drosophila melanogaster)
Insecta RpS10b 35
  • 62.42 (n)
  • 63.76 (a)
RpS10a 36
  • 55 (a)
RpS10b 36
  • 61 (a)
(Caenorhabditis elegans)
Secernentea rps-10 35
  • 61.15 (n)
  • 54.14 (a)
rps-10 36
  • 50 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPS10A 36
  • 53 (a)
RPS10B 36
  • 52 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G52650 35
  • 57.45 (n)
  • 56.1 (a)
(Oryza sativa)
Liliopsida Os04g0430100 35
  • 57.26 (n)
  • 51.28 (a)
Species with no ortholog for RPS10-NUDT3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RPS10-NUDT3 Gene

Gene Tree for RPS10-NUDT3 (if available)
Gene Tree for RPS10-NUDT3 (if available)

Paralogs for RPS10-NUDT3 Gene

Paralogs for RPS10-NUDT3 Gene

(6) SIMAP similar genes for RPS10-NUDT3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RPS10-NUDT3: view

Variants for RPS10-NUDT3 Gene

Sequence variations from dbSNP and Humsavar for RPS10-NUDT3 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs368314 -- 34,416,866(+) tctga(A/G)acagg intron-variant
rs576137 -- 34,402,638(-) gtgcc(A/C)ccaca intron-variant
rs640926 -- 34,411,511(+) tagta(A/G)agacg intron-variant
rs1212156 -- 34,416,798(+) tcatc(A/C)caaaa intron-variant
rs1212513 -- 34,415,865(+) ttttg(G/T)ggaga intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RPS10-NUDT3 Gene

Variant ID Type Subtype PubMed ID
nsv5253 CNV Insertion 18451855
esv29044 CNV Loss 19812545
esv2731907 CNV Deletion 23290073
dgv1115e199 CNV Deletion 23128226
esv33496 CNV Loss 17666407
esv2674771 CNV Deletion 23128226
esv1159599 CNV Insertion 17803354
dgv1938e1 CNV Complex 17122850

Relevant External Links for RPS10-NUDT3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPS10-NUDT3 Gene

Disorders for RPS10-NUDT3 Gene

No disorders were found for RPS10-NUDT3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for RPS10-NUDT3 Gene

Publications for RPS10-NUDT3 Gene

  1. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  2. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PMID: 20935630) Speliotes E.K. … Loos R.J. (Nat. Genet. 2010) 3
  3. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3
  4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3

Products for RPS10-NUDT3 Gene

Sources for RPS10-NUDT3 Gene

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